sevoflurane has been researched along with Cognition Disorders in 58 studies
Sevoflurane: A non-explosive inhalation anesthetic used in the induction and maintenance of general anesthesia. It does not cause respiratory irritation and may also prevent PLATELET AGGREGATION.
sevoflurane : An ether compound having fluoromethyl and 1,1,1,3,3,3-hexafluoroisopropyl as the two alkyl groups.
Cognition Disorders: Disorders characterized by disturbances in mental processes related to learning, thinking, reasoning, and judgment.
| Excerpt | Relevance | Reference |
|---|---|---|
| " This study was designed to compare the effects of propofol and sevoflurane anesthesia on recovery characteristics and the incidence of post-operative delirium (POD) in long-duration laparoscopic surgery for elderly patients." | 9.11 | Recovery characteristics and post-operative delirium after long-duration laparoscope-assisted surgery in elderly patients: propofol-based vs. sevoflurane-based anesthesia. ( Nakayama, M; Namiki, A; Nishikawa, K; Omote, K, 2004) |
| " Therefore, the present study evaluates cognitive and behavioral function as well as hippocampal damage in rats subjected to cerebral ischemia under sevoflurane compared with fentanyl/nitrous oxide (N(2)O)/O(2) anesthesia." | 7.75 | Effects of sevoflurane on cognitive deficit, motor function, and histopathology after cerebral ischemia in rats. ( Blobner, M; Eberspächer, E; Eckel, B; Engelhard, K; Hoffman, WE; Müller, K; Werner, C, 2009) |
| "Although preoperative sleep deprivation is known to be an independent risk factor for postoperative cognitive dysfunction (POCD) after inhalation anesthesia, the circadian mechanisms involved are currently unclear." | 5.51 | REM sleep deprivation-induced circadian clock gene abnormalities participate in hippocampal-dependent memory impairment by enhancing inflammation in rats undergoing sevoflurane inhalation. ( Hou, J; Shen, Q; Wan, X; Wu, Y; Xia, Z; Zhao, B, 2019) |
| " Recently, we have found that sevoflurane anesthesia during pregnancy in mice-induced cognitive impairment in the offspring by causing iron deficiency and inhibiting myelinogenesis." | 5.12 | Prenatal sevoflurane exposure: Effects of iron metabolic dysfunction on offspring cognition and potential mechanism. ( Chang, Y; Shi, Z; Thirupathi, A; Zhou, C; Zuo, Y, 2021) |
| " This study was designed to compare the effects of propofol and sevoflurane anesthesia on recovery characteristics and the incidence of post-operative delirium (POD) in long-duration laparoscopic surgery for elderly patients." | 5.11 | Recovery characteristics and post-operative delirium after long-duration laparoscope-assisted surgery in elderly patients: propofol-based vs. sevoflurane-based anesthesia. ( Nakayama, M; Namiki, A; Nishikawa, K; Omote, K, 2004) |
| "We are uncertain whether maintenance with propofol-based TIVA or with inhalational agents affect incidences of postoperative delirium, mortality, or length of hospital stay because certainty of the evidence was very low." | 4.98 | Intravenous versus inhalational maintenance of anaesthesia for postoperative cognitive outcomes in elderly people undergoing non-cardiac surgery. ( Alderson, P; Lewis, SR; Miller, D; Pritchard, MW; Schofield-Robinson, OJ; Shelton, CL; Smith, AF, 2018) |
| " Therefore, the present study evaluates cognitive and behavioral function as well as hippocampal damage in rats subjected to cerebral ischemia under sevoflurane compared with fentanyl/nitrous oxide (N(2)O)/O(2) anesthesia." | 3.75 | Effects of sevoflurane on cognitive deficit, motor function, and histopathology after cerebral ischemia in rats. ( Blobner, M; Eberspächer, E; Eckel, B; Engelhard, K; Hoffman, WE; Müller, K; Werner, C, 2009) |
| "To explore the effect of general anesthesia combined with epidural anesthesia and patient-controlled epidural analgesia on the incidence of the post-operative cognitive dysfunction (POCD) in elderly patients." | 2.82 | [Incidence of the post-operative cognitive dysfunction in elderly patients with general anesthesia combined with epidural anesthesia and patient-controlled epidural analgesia]. ( Li, H; Liu, X; Wang, Y, 2016) |
| "Desflurane was associated with a faster early recovery than sevoflurane in elderly patients." | 2.78 | Post-operative cognitive functions after general anesthesia with sevoflurane and desflurane in South Asian elderly. ( Deepak, TS; Kempegowda, P; Kumar, KS; Vadlamani, S, 2013) |
| "Sevoflurane is a widely used general anaesthetic in paediatric patients." | 1.91 | Repeated sevoflurane exposures inhibit neurogenesis by inducing the upregulation of glutamate transporter 1 in astrocytes. ( Feng, C; Kong, F; Wang, T; Wu, Y; Zhang, Y; Zhong, L, 2023) |
| "Although preoperative sleep deprivation is known to be an independent risk factor for postoperative cognitive dysfunction (POCD) after inhalation anesthesia, the circadian mechanisms involved are currently unclear." | 1.51 | REM sleep deprivation-induced circadian clock gene abnormalities participate in hippocampal-dependent memory impairment by enhancing inflammation in rats undergoing sevoflurane inhalation. ( Hou, J; Shen, Q; Wan, X; Wu, Y; Xia, Z; Zhao, B, 2019) |
| "Sevoflurane is a commonly used anesthetic in children." | 1.40 | Sevoflurane induces tau phosphorylation and glycogen synthase kinase 3β activation in young mice. ( Crosby, G; Culley, DJ; Dong, Y; Tao, G; Xie, Z; Yu, B; Zhang, J; Zhang, L; Zhang, Y, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 11 (18.97) | 29.6817 |
| 2010's | 41 (70.69) | 24.3611 |
| 2020's | 6 (10.34) | 2.80 |
| Authors | Studies |
|---|---|
| Kong, F | 3 |
| Zhang, Y | 7 |
| Wang, T | 3 |
| Zhong, L | 3 |
| Feng, C | 3 |
| Wu, Y | 5 |
| Chastain-Potts, SE | 1 |
| Tesic, V | 1 |
| Tat, QL | 1 |
| Cabrera, OH | 1 |
| Quillinan, N | 1 |
| Jevtovic-Todorovic, V | 1 |
| Song, SY | 1 |
| Meng, XW | 1 |
| Xia, Z | 2 |
| Liu, H | 1 |
| Zhang, J | 2 |
| Chen, QC | 1 |
| Liu, HY | 1 |
| Ji, FH | 1 |
| Peng, K | 1 |
| Nir, T | 1 |
| Jacob, Y | 1 |
| Huang, KH | 1 |
| Schwartz, AE | 1 |
| Brallier, JW | 1 |
| Ahn, H | 1 |
| Kundu, P | 1 |
| Tang, CY | 1 |
| Delman, BN | 1 |
| McCormick, PJ | 1 |
| Sano, M | 1 |
| Deiner, S | 1 |
| Baxter, MG | 2 |
| Mincer, JS | 1 |
| Neymark, MI | 1 |
| Shmelev, VV | 2 |
| Rakhmonov, AA | 1 |
| Zuo, Y | 1 |
| Chang, Y | 1 |
| Thirupathi, A | 1 |
| Zhou, C | 1 |
| Shi, Z | 1 |
| Qu, Y | 1 |
| Li, H | 2 |
| Shi, C | 1 |
| Qian, M | 1 |
| Yang, N | 1 |
| Wang, L | 2 |
| Gao, X | 1 |
| Ni, C | 2 |
| Xia, Y | 1 |
| Xu, H | 1 |
| Jia, C | 1 |
| Hu, X | 1 |
| Kang, Y | 1 |
| Yang, X | 1 |
| Xue, Q | 1 |
| Tao, G | 2 |
| Yu, B | 2 |
| Xu, G | 1 |
| Lu, H | 1 |
| Dong, Y | 3 |
| Shapoval, D | 1 |
| Soriano, SG | 2 |
| Liu, X | 2 |
| Xie, Z | 3 |
| Lv, X | 1 |
| Yan, J | 1 |
| Jiang, J | 1 |
| Zhou, X | 1 |
| Lu, Y | 1 |
| Jiang, H | 1 |
| Miller, D | 1 |
| Lewis, SR | 1 |
| Pritchard, MW | 1 |
| Schofield-Robinson, OJ | 1 |
| Shelton, CL | 1 |
| Alderson, P | 1 |
| Smith, AF | 1 |
| Liang, LQ | 1 |
| Jiao, YQ | 1 |
| Guo, SL | 1 |
| Hou, J | 1 |
| Shen, Q | 1 |
| Wan, X | 1 |
| Zhao, B | 1 |
| Xu, JH | 1 |
| Zhang, TZ | 1 |
| Peng, XF | 1 |
| Jin, CJ | 1 |
| Zhou, J | 1 |
| Zhang, YN | 1 |
| Neimark, MI | 1 |
| Deepak, TS | 1 |
| Vadlamani, S | 1 |
| Kumar, KS | 1 |
| Kempegowda, P | 1 |
| Rong, YL | 1 |
| Jia, DL | 1 |
| Li, G | 1 |
| Yu, C | 1 |
| Li, N | 1 |
| Wang, J | 1 |
| Guo, XY | 1 |
| Hu, N | 3 |
| Guo, D | 1 |
| Wang, H | 4 |
| Xie, K | 3 |
| Wang, C | 8 |
| Li, Y | 3 |
| Yu, Y | 3 |
| Wang, G | 3 |
| Pellegrini, L | 1 |
| Bennis, Y | 1 |
| Velly, L | 1 |
| Grandvuillemin, I | 1 |
| Pisano, P | 1 |
| Bruder, N | 1 |
| Guillet, B | 1 |
| Zhang, L | 1 |
| Crosby, G | 1 |
| Culley, DJ | 1 |
| Tian, Y | 1 |
| Guo, S | 1 |
| Wu, X | 1 |
| Ma, L | 1 |
| Zhao, X | 2 |
| Xie, H | 1 |
| She, GM | 1 |
| Zhang, LY | 1 |
| Liu, CF | 1 |
| Acharya, NK | 1 |
| Goldwaser, EL | 1 |
| Forsberg, MM | 1 |
| Godsey, GA | 1 |
| Johnson, CA | 1 |
| Sarkar, A | 1 |
| DeMarshall, C | 1 |
| Kosciuk, MC | 1 |
| Dash, JM | 1 |
| Hale, CP | 1 |
| Leonard, DM | 1 |
| Appelt, DM | 1 |
| Nagele, RG | 1 |
| Wang, M | 1 |
| Ji, MH | 3 |
| Wang, XM | 1 |
| Sun, XR | 2 |
| Zhang, H | 3 |
| Ju, LS | 2 |
| Qiu, LL | 2 |
| Yang, JJ | 4 |
| Jia, M | 3 |
| Wu, J | 1 |
| Yang, J | 2 |
| Zhao, Y | 2 |
| Chen, K | 1 |
| Shen, X | 2 |
| Ling, YZ | 1 |
| Ma, W | 1 |
| Yu, L | 1 |
| Liang, QS | 1 |
| Zhang, MQ | 1 |
| Zhao, QS | 1 |
| Peng, YG | 1 |
| Martynyuk, AE | 1 |
| Qiao, Y | 1 |
| Feng, H | 1 |
| Zhao, T | 1 |
| Yan, H | 1 |
| Yue, T | 1 |
| Shanbin, G | 1 |
| Ling, M | 1 |
| Yuan, W | 1 |
| Ying, X | 1 |
| Ping, Z | 1 |
| Sun, J | 1 |
| Wang, ZY | 1 |
| Zheng, Y | 1 |
| Ao, J | 1 |
| Zhang, C | 1 |
| Zhang, X | 2 |
| Zhou, Y | 1 |
| Xu, M | 1 |
| Chen, G | 2 |
| Poor Zamany Nejat Kermany, M | 1 |
| Roodneshin, F | 1 |
| Ahmadi Dizgah, N | 1 |
| Gerami, E | 1 |
| Riahi, E | 1 |
| Egawa, J | 1 |
| Inoue, S | 1 |
| Nishiwada, T | 1 |
| Tojo, T | 1 |
| Kimura, M | 1 |
| Kawaguchi, T | 1 |
| Taniguchi, S | 1 |
| Furuya, H | 1 |
| Kawaguchi, M | 1 |
| Fang, F | 1 |
| Lin, W | 1 |
| Ling, X | 1 |
| Song, R | 1 |
| Liu, Q | 1 |
| Lai, B | 1 |
| Cang, J | 1 |
| Wang, Y | 2 |
| Liu, J | 1 |
| Zhang, W | 1 |
| Wang, P | 1 |
| Zhu, Y | 1 |
| Yao, R | 1 |
| Hao, T | 1 |
| Cao, J | 1 |
| Huang, H | 1 |
| Li, XH | 1 |
| Zuo, YX | 1 |
| Mandal, PK | 1 |
| Schifilliti, D | 1 |
| Mafrica, F | 1 |
| Fodale, V | 1 |
| Eberspächer, E | 1 |
| Eckel, B | 1 |
| Engelhard, K | 1 |
| Müller, K | 1 |
| Hoffman, WE | 1 |
| Blobner, M | 1 |
| Werner, C | 1 |
| Sanders, RD | 1 |
| Maze, M | 1 |
| Rörtgen, D | 1 |
| Kloos, J | 1 |
| Fries, M | 1 |
| Grottke, O | 1 |
| Rex, S | 1 |
| Rossaint, R | 1 |
| Coburn, M | 1 |
| Bilotta, F | 1 |
| Doronzio, A | 1 |
| Stazi, E | 1 |
| Titi, L | 1 |
| Zeppa, IO | 1 |
| Cianchi, A | 1 |
| Rosa, G | 1 |
| Paoloni, FP | 1 |
| Bergese, S | 1 |
| Asouhidou, I | 1 |
| Ioannou, P | 1 |
| Abramowicz, AE | 1 |
| Spinelli, A | 1 |
| Delphin, E | 1 |
| Ayrian, E | 1 |
| Zelman, V | 1 |
| Lumb, P | 1 |
| Eckenhoff, RG | 1 |
| Planel, E | 1 |
| Le Freche, H | 1 |
| Brouillette, J | 1 |
| Fernandez-Gomez, FJ | 1 |
| Patin, P | 1 |
| Caillierez, R | 1 |
| Zommer, N | 1 |
| Sergeant, N | 1 |
| Buée-Scherrer, V | 1 |
| Lebuffe, G | 1 |
| Blum, D | 1 |
| Buée, L | 1 |
| Gong, M | 1 |
| Zhang, XM | 1 |
| Xu, LH | 1 |
| Wang, HM | 1 |
| Yan, M | 1 |
| Xu, Z | 1 |
| Miao, C | 1 |
| Sun, D | 1 |
| Nishikawa, K | 1 |
| Nakayama, M | 1 |
| Omote, K | 1 |
| Namiki, A | 1 |
| Iohom, G | 1 |
| Szarvas, S | 1 |
| Larney, V | 1 |
| O'Brien, J | 1 |
| Buckley, E | 1 |
| Butler, M | 1 |
| Shorten, G | 1 |
| Rohan, D | 1 |
| Buggy, DJ | 1 |
| Crowley, S | 1 |
| Ling, FK | 1 |
| Gallagher, H | 1 |
| Regan, C | 1 |
| Moriarty, DC | 1 |
| Millar, K | 1 |
| Asbury, AJ | 1 |
| Bowman, AW | 1 |
| Hosey, MT | 1 |
| Musiello, T | 1 |
| Welbury, RR | 1 |
| Stanford, J | 1 |
| Kanbak, M | 1 |
| Saricaoglu, F | 1 |
| Akinci, SB | 1 |
| Oc, B | 1 |
| Balci, H | 1 |
| Celebioglu, B | 1 |
| Aypar, U | 1 |
| Mahajan, VA | 1 |
| Ni Chonghaile, M | 1 |
| Bokhari, SA | 1 |
| Harte, BH | 1 |
| Flynn, NM | 1 |
| Laffey, JG | 1 |
| Kadoi, Y | 1 |
| Goto, F | 1 |
| Biedler, A | 1 |
| Juckenhöfel, S | 1 |
| Feisel, C | 1 |
| Wilhelm, W | 1 |
| Larsen, R | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Trajectory of Recovery in the Elderly[NCT02275026] | 104 participants (Actual) | Interventional | 2015-07-31 | Completed | |||
| Comparison of the Effects of Total Intravenous Anesthesia and Inhalation Anesthesia on Lymphocytes in Patients Undergoing Colorectal Cancer Resection and the Mechanism Involved: a Single-center, Randomized, Prospective Study[NCT03193710] | 260 participants (Anticipated) | Observational | 2017-09-01 | Recruiting | |||
| [NCT02909413] | 600 participants (Anticipated) | Interventional | 2016-10-31 | Not yet recruiting | |||
| Post Operative Cognitive Recovery and Neuropsychological Complications After General Anesthesia. A Comparison Between Different Techniques of Anesthesia: A Multi-Center Observational Study[NCT00507195] | 1,200 participants (Anticipated) | Observational | 2007-05-31 | Recruiting | |||
| Could Music be an Alternative to Sedation in Patients Treated Total Knee Arthroplasty With Regional Anesthesia?: A Randomized Clinical Trial[NCT03882541] | 85 participants (Actual) | Interventional | 2017-01-08 | Completed | |||
| Namenda as Prevention for Post-Operative Delirium[NCT00303433] | Phase 4 | 30 participants | Interventional | 2006-03-31 | Terminated | ||
| Impact of Inhalational Versus Intravenous Anesthesia Maintenance Methods on Incidence of Postoperative Delirium in Elderly Patients After Cancer Surgery: An Open-label, Randomized Controlled Trial[NCT02662257] | 1,228 participants (Actual) | Interventional | 2015-04-01 | Completed | |||
| Effect of Remifentanil on Postoperative Cognitive Function in Patients Undergoing Major Abdominal Surgery[NCT01627873] | Phase 4 | 622 participants (Actual) | Interventional | 2009-08-31 | Completed | ||
| Prospective Randomised Controled Trial: Comparison of Volatile Anaesthetics Sevoflurane vs. Isoflurane for Low-Flow General Anaesthesia for Abdominal Surgery[NCT00521612] | 82 participants (Actual) | Interventional | 2007-09-30 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
NIH Toolbox Cognitive Battery is a multidimensional set of brief measures assessing cognitive (as well as emotional, motor and sensory) function. There is no score range, but mean score is 100 with standard deviation 15. A score at or near 100 indicates average ability compared with others. Scores around 115 suggest above-average ability. Scores around 130 suggest superior ability (in the top 2 percent nationally). A score around 85 suggests below-average ability. A score in the range of 70 or below suggests significant impairment. (NCT02275026)
Timeframe: Baseline, 1 day, 7 days, 30 days
| Intervention | score on a scale (Least Squares Mean) | |||
|---|---|---|---|---|
| Baseline | 1 day | 7 days | 30 days | |
| Age Decade 40-49 | 48.1 | 52.2 | 54.8 | 54.5 |
| Age Decade 50-59 | 53.3 | 57.2 | 59.4 | 59.5 |
| Age Decade 60-69 | 50.1 | 53.2 | 54.6 | 54.4 |
| Age Decade 70-80 | 54 | 57.4 | 54.4 | 59.6 |
Cognitive Function using scales of the PQRS to test whether age is associated with the time of return to baseline cognitive function. The PQRS is a brief measurement tool to assess multiple domains of recovery, including cognition, over time. It is scored as recovered / not recovered based on level of performance, within a certain tolerance range, relative to preoperative (baseline) performance - before the general anesthesia / MRI scanning session. Postoperative Quality of Recovery Cognitive Scale at each study timepoint by age decade. Postoperative Quality of Recovery Cognitive (NCT02275026)
Timeframe: 15 min, 60 min, 1 day, 3 days, 7 days, 30 days, 6 months
| Intervention | Participants (Count of Participants) | ||||||
|---|---|---|---|---|---|---|---|
| at 15 min | at 60 min | 1 day | 3 days | 7 days | 30 days | 6 months | |
| Age Decade 40-49 | 3 | 8 | 17 | 18 | 18 | 18 | 19 |
| Age Decade 50-59 | 5 | 11 | 18 | 19 | 19 | 19 | 19 |
| Age Decade 60-69 | 1 | 8 | 12 | 12 | 12 | 12 | 13 |
| Age Decade 70-80 | 3 | 9 | 16 | 17 | 17 | 18 | 18 |
3 reviews available for sevoflurane and Cognition Disorders
| Article | Year |
|---|---|
Prenatal sevoflurane exposure: Effects of iron metabolic dysfunction on offspring cognition and potential mechanism.
Topics: Adult; Anesthesia, General; Anesthetics, Inhalation; Animals; Cognition Disorders; Female; Humans; I | 2021 |
Intravenous versus inhalational maintenance of anaesthesia for postoperative cognitive outcomes in elderly people undergoing non-cardiac surgery.
Topics: Aged; Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthetics, Inhalation; Anesthetics, Intrave | 2018 |
Inhaled anesthesia and cognitive performance.
Topics: Age Factors; Aged; Anesthetics, Inhalation; Cognition Disorders; Desflurane; Humans; Isoflurane; Met | 2009 |
14 trials available for sevoflurane and Cognition Disorders
| Article | Year |
|---|---|
Effects of sevoflurane before cardiopulmonary bypass on cerebral oxygen balance and early postoperative cognitive dysfunction.
Topics: Anesthetics, Inhalation; Brain; Cardiopulmonary Bypass; Cognition Disorders; Female; Humans; Male; M | 2013 |
Post-operative cognitive functions after general anesthesia with sevoflurane and desflurane in South Asian elderly.
Topics: Aged; Aged, 80 and over; Anesthesia Recovery Period; Anesthesia, General; Anesthetics, Inhalation; C | 2013 |
Postoperative cognitive dysfunction after inhalational anesthesia in elderly patients undergoing major surgery: the influence of anesthetic technique, cerebral injury and systemic inflammation.
Topics: Aged; Anesthetics, Inhalation; Anesthetics, Intravenous; Cognition Disorders; Double-Blind Method; E | 2015 |
Effects of anesthetics on early postoperative cognitive outcome and intraoperative cerebral oxygen balance in patients undergoing lung surgery: a randomized clinical trial.
Topics: Age Factors; Aged; Anesthetics, Inhalation; Anesthetics, Intravenous; Brain Chemistry; Cognition Dis | 2016 |
[Incidence of the post-operative cognitive dysfunction in elderly patients with general anesthesia combined with epidural anesthesia and patient-controlled epidural analgesia].
Topics: Analgesia, Epidural; Analgesia, Patient-Controlled; Anesthesia, Epidural; Anesthesia, General; Cogni | 2016 |
Comparison of early cognitive function and recovery after desflurane or sevoflurane anaesthesia in the elderly: a double-blinded randomized controlled trial.
Topics: Aged; Anesthesia Recovery Period; Anesthetics, Inhalation; Cognition Disorders; Desflurane; Double-B | 2010 |
Early postoperative cognitive dysfunction and postoperative delirium after anaesthesia with various hypnotics: study protocol for a randomised controlled trial--the PINOCCHIO trial.
Topics: Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intravenous; Cognition; Cognition Disorde | 2011 |
Recovery characteristics and post-operative delirium after long-duration laparoscope-assisted surgery in elderly patients: propofol-based vs. sevoflurane-based anesthesia.
Topics: Aged; Analgesia, Epidural; Cognition Disorders; Delirium; Female; Humans; Incidence; Laparoscopy; Ma | 2004 |
Recovery characteristics and post-operative delirium after long-duration laparoscope-assisted surgery in elderly patients: propofol-based vs. sevoflurane-based anesthesia.
Topics: Aged; Analgesia, Epidural; Cognition Disorders; Delirium; Female; Humans; Incidence; Laparoscopy; Ma | 2004 |
Recovery characteristics and post-operative delirium after long-duration laparoscope-assisted surgery in elderly patients: propofol-based vs. sevoflurane-based anesthesia.
Topics: Aged; Analgesia, Epidural; Cognition Disorders; Delirium; Female; Humans; Incidence; Laparoscopy; Ma | 2004 |
Recovery characteristics and post-operative delirium after long-duration laparoscope-assisted surgery in elderly patients: propofol-based vs. sevoflurane-based anesthesia.
Topics: Aged; Analgesia, Epidural; Cognition Disorders; Delirium; Female; Humans; Incidence; Laparoscopy; Ma | 2004 |
Perioperative plasma concentrations of stable nitric oxide products are predictive of cognitive dysfunction after laparoscopic cholecystectomy.
Topics: Adult; Affect; Aged; Aged, 80 and over; Algorithms; Anesthesia, Inhalation; Anesthetics, Inhalation; | 2004 |
Increased incidence of postoperative cognitive dysfunction 24 hr after minor surgery in the elderly.
Topics: Aged; Aged, 80 and over; Anesthetics, Inhalation; Anesthetics, Intravenous; Biomarkers; Cognition Di | 2005 |
The effects of brief sevoflurane-nitrous oxide anaesthesia upon children's postoperative cognition and behaviour.
Topics: Ambulatory Surgical Procedures; Anesthetics, Combined; Anesthetics, Inhalation; Child; Child Behavio | 2006 |
The effects of isoflurane, sevoflurane, and desflurane anesthesia on neurocognitive outcome after cardiac surgery: a pilot study.
Topics: Anesthesia, Inhalation; Biomarkers; Cardiac Surgical Procedures; Cardiopulmonary Bypass; Cognition D | 2007 |
Recovery of older patients undergoing ambulatory anaesthesia with isoflurane or sevoflurane.
Topics: Aged; Ambulatory Surgical Procedures; Analysis of Variance; Anesthesia, Inhalation; Anesthetics, Inh | 2007 |
[Cognitive impairment in the early postoperative period after remifentanil-propofol and sevoflurane-fentanyl anesthesia].
Topics: Adult; Anesthesia, Inhalation; Anesthetics, Inhalation; Anesthetics, Intravenous; Cognition Disorder | 2000 |
41 other studies available for sevoflurane and Cognition Disorders
| Article | Year |
|---|---|
Repeated sevoflurane exposures inhibit neurogenesis by inducing the upregulation of glutamate transporter 1 in astrocytes.
Topics: Anesthetics, Inhalation; Animals; Astrocytes; Cognition Disorders; Excitatory Amino Acid Transporter | 2023 |
Repeated sevoflurane exposures inhibit neurogenesis by inducing the upregulation of glutamate transporter 1 in astrocytes.
Topics: Anesthetics, Inhalation; Animals; Astrocytes; Cognition Disorders; Excitatory Amino Acid Transporter | 2023 |
Repeated sevoflurane exposures inhibit neurogenesis by inducing the upregulation of glutamate transporter 1 in astrocytes.
Topics: Anesthetics, Inhalation; Animals; Astrocytes; Cognition Disorders; Excitatory Amino Acid Transporter | 2023 |
Repeated sevoflurane exposures inhibit neurogenesis by inducing the upregulation of glutamate transporter 1 in astrocytes.
Topics: Anesthetics, Inhalation; Animals; Astrocytes; Cognition Disorders; Excitatory Amino Acid Transporter | 2023 |
Sevoflurane Exposure Results in Sex-Specific Transgenerational Upregulation of Target IEGs in the Subiculum.
Topics: Anesthetics, Inhalation; Animals; Animals, Newborn; Cognition Disorders; Dendritic Spines; Genes, Im | 2020 |
Cognitive impairment and transcriptomic profile in hippocampus of young mice after multiple neonatal exposures to sevoflurane.
Topics: Anesthetics, Inhalation; Animals; Behavior, Animal; Class I Phosphatidylinositol 3-Kinases; Cognitio | 2019 |
Resting-state functional connectivity in early postanaesthesia recovery is characterised by globally reduced anticorrelations.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Anesthesia Recovery Period; Anesthesia, General; Brain; | 2020 |
[Violations of higher mental functions and their correction in patients undergoing video laparoscopic cholecystectomy under conditions of inhalation anesthesia with sevoflurane].
Topics: Anesthesia, Inhalation; Anesthetics, Inhalation; Cholecystectomy, Laparoscopic; Cognition Disorders; | 2020 |
lncRNAs Are Involved in Sevoflurane Anesthesia-Related Brain Function Modulation through Affecting Mitochondrial Function and Aging Process.
Topics: Aging; Anesthesia; Anesthetics; Animals; Brain; Brain Neoplasms; Cell Line, Tumor; Cognition Disorde | 2020 |
Tanshinone IIA Attenuates Sevoflurane Neurotoxicity in Neonatal Mice.
Topics: Abietanes; Anesthetics, Inhalation; Animals; Animals, Newborn; Anti-Inflammatory Agents, Non-Steroid | 2017 |
Coenzyme Q10 reduces sevoflurane-induced cognitive deficiency in young mice.
Topics: Anesthetics, Inhalation; Animals; Cognition Disorders; Disease Models, Animal; Female; Male; Mice; M | 2017 |
MicroRNA-27a-3p suppression of peroxisome proliferator-activated receptor-γ contributes to cognitive impairments resulting from sevoflurane treatment.
Topics: Anesthetics, Inhalation; Animals; Animals, Newborn; Apoptosis; Cells, Cultured; Cognition Disorders; | 2017 |
Effects of sevoflurane inhalation anesthesia on cognitive and immune function in elderly patients after abdominal operation.
Topics: Abdomen; Age Factors; Aged; Aged, 80 and over; Anesthetics, Inhalation; Anesthetics, Intravenous; Co | 2018 |
REM sleep deprivation-induced circadian clock gene abnormalities participate in hippocampal-dependent memory impairment by enhancing inflammation in rats undergoing sevoflurane inhalation.
Topics: Animals; Circadian Clocks; Cognition Disorders; Gene Expression; Gene Expression Regulation; Hippoca | 2019 |
[The dynamics of the state of higher mental functions after surgical reconstruction of carotid stenosis using different types of anesthesia].
Topics: Aged; Anesthesia, General; Anesthesia, Intravenous; Anesthetics, Intravenous; Carotid Arteries; Caro | 2013 |
[Influence of inhaled anesthesia on bispectral index of elderly patients with cognitive decline].
Topics: Aged; Aged, 80 and over; Anesthesia Recovery Period; Anesthesia, Inhalation; Cognition; Cognition Di | 2013 |
Involvement of the blood-brain barrier opening in cognitive decline in aged rats following orthopedic surgery and high concentration of sevoflurane inhalation.
Topics: Anesthetics, Inhalation; Animals; Blood-Brain Barrier; Cognition Disorders; Hippocampus; Male; Methy | 2014 |
Erythropoietin protects newborn rat against sevoflurane-induced neurotoxicity.
Topics: Anesthetics, Inhalation; Animals; Animals, Newborn; Apoptosis; Blood Gas Analysis; Brain; Cognition | 2014 |
Sevoflurane induces tau phosphorylation and glycogen synthase kinase 3β activation in young mice.
Topics: Aging; Anesthetics, Inhalation; Animals; Cognition Disorders; Enzyme Activation; Escape Reaction; Fe | 2014 |
Minocycline alleviates sevoflurane-induced cognitive impairment in aged rats.
Topics: Aging; Amyloid beta-Peptides; Animals; Apoptosis; Cognition Disorders; Hippocampus; Inflammation; Le | 2015 |
The gender difference in effect of sevoflurane exposure on cognitive function and hippocampus neuronal apoptosis in rats.
Topics: Anesthetics, Inhalation; Animals; Apoptosis; Caspase 3; Cognition; Cognition Disorders; Cyclic AMP R | 2015 |
Sevoflurane and Isoflurane induce structural changes in brain vascular endothelial cells and increase blood-brain barrier permeability: Possible link to postoperative delirium and cognitive decline.
Topics: Aging; Anesthetics, Inhalation; Animals; Blood-Brain Barrier; Capillary Permeability; Cognition Diso | 2015 |
Internalization of GluA2 and the underlying mechanisms of cognitive decline in aged rats following surgery and prolonged exposure to sevoflurane.
Topics: Aging; Anesthetics, Inhalation; Animals; Cognition Disorders; Conditioning, Psychological; Fear; Gen | 2015 |
Environmental Enrichment Ameliorates Neonatal Sevoflurane Exposure-Induced Cognitive and Synaptic Plasticity Impairments.
Topics: Anesthetics, Inhalation; Animals; Animals, Newborn; Cognition Disorders; Conditioning, Classical; De | 2015 |
Environmental Enrichment Attenuated Sevoflurane-Induced Neurotoxicity through the PPAR-γ Signaling Pathway.
Topics: Animals; Apoptosis; Cognition Disorders; Down-Regulation; Environment; Male; Memory Disorders; Methy | 2015 |
Decreased PSD95 expression in medial prefrontal cortex (mPFC) was associated with cognitive impairment induced by sevoflurane anesthesia.
Topics: Anesthetics, Inhalation; Animals; Cognition Disorders; Disks Large Homolog 4 Protein; Dose-Response | 2015 |
Neurobehavioural abnormalities induced by repeated exposure of neonatal rats to sevoflurane can be aggravated by social isolation and enrichment deprivation initiated after exposure to the anaesthetic.
Topics: Anesthetics, Inhalation; Animals; Animals, Newborn; Behavior, Animal; Brain-Derived Neurotrophic Fac | 2015 |
Sevoflurane aggregates cognitive dysfunction and hippocampal oxidative stress induced by β-amyloid in rats.
Topics: Amyloid beta-Peptides; Animals; Cognition Disorders; Hippocampus; Male; Methyl Ethers; Oxidative Str | 2015 |
Hypermethylation of Hippocampal Synaptic Plasticity-Related genes is Involved in Neonatal Sevoflurane Exposure-Induced Cognitive Impairments in Rats.
Topics: Anesthetics, Inhalation; Animals; Animals, Newborn; Azacitidine; Brain-Derived Neurotrophic Factor; | 2016 |
The role of the Wnt/β-catenin-Annexin A1 pathway in the process of sevoflurane-induced cognitive dysfunction.
Topics: Animals; Annexin A1; beta Catenin; Cells, Cultured; Cerebellum; Cognition Disorders; Conditioning, C | 2016 |
Autophagy Is Involved in the Sevoflurane Anesthesia-Induced Cognitive Dysfunction of Aged Rats.
Topics: Anesthetics, Inhalation; Animals; Autophagy; Cognition Disorders; Male; Methyl Ethers; Rats; Rats, S | 2016 |
Early childhood exposure to short periods of sevoflurane is not associated with later, lasting cognitive deficits.
Topics: Adolescent; Anesthetics, Inhalation; Brain; Child; Child, Preschool; Cognition Disorders; Cohort Stu | 2016 |
The hippocampal cyclin D1 expression is involved in postoperative cognitive dysfunction after sevoflurane exposure in aged mice.
Topics: Aging; Anesthetics, Inhalation; Animals; Cognition Disorders; Cyclin D1; Hippocampus; Maze Learning; | 2016 |
Neonatal Repeated Exposure to Isoflurane not Sevoflurane in Mice Reversibly Impaired Spatial Cognition at Juvenile-Age.
Topics: Anesthetics, Inhalation; Animals; Animals, Newborn; Cognition Disorders; Isoflurane; Male; Maze Lear | 2017 |
Enhanced neuroinflammation mediated by DNA methylation of the glucocorticoid receptor triggers cognitive dysfunction after sevoflurane anesthesia in adult rats subjected to maternal separation during the neonatal period.
Topics: Anesthetics, Inhalation; Animals; Astrocytes; Cognition Disorders; Conditioning, Psychological; Cyto | 2017 |
Correspondence Letter to the Editor regarding 'Early childhood exposure to short periods of sevoflurane is not associated with later, lasting cognitive deficits'.
Topics: Cognition; Cognition Disorders; Humans; Methyl Ethers; Sevoflurane | 2017 |
Effects of sevoflurane on cognitive deficit, motor function, and histopathology after cerebral ischemia in rats.
Topics: Anesthesia; Anesthetics; Anesthetics, Intravenous; Animals; Blood Gas Analysis; Brain; Brain Ischemi | 2009 |
Neuroinflammation and postoperative cognitive dysfunction: can anaesthesia be therapeutic?
Topics: Aged; Anesthesia; Anesthetics, Inhalation; Animals; Cognition Disorders; Coronary Vessels; Humans; I | 2010 |
Postoperative cognitive decline: where art tau?
Topics: Anesthesia, General; Animals; Cognition Disorders; Female; Methyl Ethers; Sevoflurane; tau Proteins | 2012 |
Tau phosphorylation and sevoflurane anesthesia: an association to postoperative cognitive impairment.
Topics: Acute Disease; Anesthesia, General; Animals; Chronic Disease; Cognition Disorders; Female; Methyl Et | 2012 |
Parecoxib mitigates spatial memory impairment induced by sevoflurane anesthesia in aged rats.
Topics: Aging; Anesthetics, Intravenous; Animals; Blotting, Western; Cognition Disorders; Cyclooxygenase 2; | 2012 |
Selective anesthesia-induced neuroinflammation in developing mouse brain and cognitive impairment.
Topics: Age Factors; Anesthetics, Inhalation; Animals; Brain; Cognition Disorders; Desflurane; Drug Therapy, | 2013 |
The effects of general anaesthesia on children.
Topics: Anesthesia, General; Anesthetics, Inhalation; Child; Child Behavior Disorders; Cognition Disorders; | 2006 |
Sevoflurane anesthesia did not affect postoperative cognitive dysfunction in patients undergoing coronary artery bypass graft surgery.
Topics: Age Factors; Aged; Anesthesia, Inhalation; Anesthetics, Inhalation; Cognition Disorders; Coronary Ar | 2007 |