sevoflurane has been researched along with Chemical and Drug Induced Liver Injury in 39 studies
Sevoflurane: A non-explosive inhalation anesthetic used in the induction and maintenance of general anesthesia. It does not cause respiratory irritation and may also prevent PLATELET AGGREGATION.
sevoflurane : An ether compound having fluoromethyl and 1,1,1,3,3,3-hexafluoroisopropyl as the two alkyl groups.
Chemical and Drug Induced Liver Injury: A spectrum of clinical liver diseases ranging from mild biochemical abnormalities to ACUTE LIVER FAILURE, caused by drugs, drug metabolites, herbal and dietary supplements and chemicals from the environment.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Propofol infusion syndrome is a rare condition that mainly affects critically ill patients who receive high doses of this hypnotic for a long time." | 7.96 | Propofol infusion syndrome; are high doses always required? ( Boliart de San Félix, Y; Fernández Morales, M; Sánchez Royo, E; Subirà González, A; Vila Lolo, C, 2020) |
| "Hepatic ischemia induced significant degree of I/R injuries in both isoflurane and sevoflurane non-IP groups." | 7.85 | Ischemic Preconditioning Produces Comparable Protection Against Hepatic Ischemia/Reperfusion Injury Under Isoflurane and Sevoflurane Anesthesia in Rats. ( Gwak, MS; Han, S; Jeong, JS; Kim, D; Kim, GS; Kim, KY; Ko, JS; Ryu, S; Shin, BS, 2017) |
| "Propofol infusion syndrome is a rare condition that mainly affects critically ill patients who receive high doses of this hypnotic for a long time." | 3.96 | Propofol infusion syndrome; are high doses always required? ( Boliart de San Félix, Y; Fernández Morales, M; Sánchez Royo, E; Subirà González, A; Vila Lolo, C, 2020) |
| "Hepatic ischemia induced significant degree of I/R injuries in both isoflurane and sevoflurane non-IP groups." | 3.85 | Ischemic Preconditioning Produces Comparable Protection Against Hepatic Ischemia/Reperfusion Injury Under Isoflurane and Sevoflurane Anesthesia in Rats. ( Gwak, MS; Han, S; Jeong, JS; Kim, D; Kim, GS; Kim, KY; Ko, JS; Ryu, S; Shin, BS, 2017) |
| "The liver of all rats given halothane (14% O(2)) had extensive centrilobular necrosis and denaturation." | 3.73 | Ca2+ cytochemical changes of hepatotoxicity caused by halothane and sevoflurane in enzyme-induced hypoxic rats. ( Li, Q; Liu, ZQ; Yang, LQ; Yu, WF; Zhou, MT, 2005) |
| "Sevoflurane is a volatile anesthetic agent that does not tend to cause clinically significant hepatotoxicity, but there are some reported hepatotoxicity cases in the literature." | 1.91 | Acute Fulminant Hepatic Failure Caused by Sevoflurane Linked to Influenza A. ( Arslan, G; Karaarslan, U; Koker, A; Köroğlu, T; Özden, Ö, 2023) |
| "Sevoflurane has rarely been related to this life-threatening complication." | 1.91 | Fatal hepatotoxicity due to sevoflurane use in a paediatric patient after aortic repair: reality or fiction? A case of pharmacovigilance. ( Adames, V; Pichardo, P; Pradegan, N; Sanchez, LV; Zovi, A, 2023) |
| "Two days after the operation, a hepatomegaly was diagnosed, and a considerable increase in liver enzymes was observed." | 1.32 | Hepatitis after sevoflurane exposure in an infant suffering from primary hyperoxaluria type 1. ( Brinkmann, OA; Bulla, M; Everding, AS; Reich, A; Van Aken, H, 2004) |
| "Isoflurane was included for comparative purposes." | 1.28 | Sevoflurane is biotransformed by guinea pig liver slices but causes minimal cytotoxicity. ( Brendel, K; Fernando, J; Gandolfi, AJ; Ghantous, HN, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 11 (28.21) | 18.2507 |
| 2000's | 10 (25.64) | 29.6817 |
| 2010's | 14 (35.90) | 24.3611 |
| 2020's | 4 (10.26) | 2.80 |
| Authors | Studies |
|---|---|
| Fourches, D | 1 |
| Barnes, JC | 1 |
| Day, NC | 1 |
| Bradley, P | 1 |
| Reed, JZ | 1 |
| Tropsha, A | 1 |
| Liu, Z | 1 |
| Shi, Q | 1 |
| Ding, D | 1 |
| Kelly, R | 1 |
| Fang, H | 1 |
| Tong, W | 1 |
| Koker, A | 1 |
| Arslan, G | 1 |
| Özden, Ö | 1 |
| Karaarslan, U | 1 |
| Köroğlu, T | 1 |
| Mizobe, T | 1 |
| Subirà González, A | 1 |
| Fernández Morales, M | 1 |
| Sánchez Royo, E | 1 |
| Boliart de San Félix, Y | 1 |
| Vila Lolo, C | 1 |
| Sanchez, LV | 1 |
| Pichardo, P | 1 |
| Adames, V | 1 |
| Zovi, A | 1 |
| Pradegan, N | 1 |
| Jeong, JS | 1 |
| Kim, D | 1 |
| Kim, KY | 1 |
| Ryu, S | 1 |
| Han, S | 1 |
| Shin, BS | 1 |
| Kim, GS | 1 |
| Gwak, MS | 1 |
| Ko, JS | 1 |
| Ma, L | 1 |
| Zhao, J | 1 |
| Xie, X | 1 |
| Bishop, B | 2 |
| Hannah, N | 1 |
| Doyle, A | 1 |
| Amico, F | 1 |
| Hockey, B | 3 |
| Moore, D | 3 |
| Sood, S | 2 |
| Gorelik, A | 2 |
| Liew, D | 2 |
| Njoku, D | 3 |
| Nicoll, A | 4 |
| Rajan, S | 1 |
| Garg, D | 1 |
| Cummings, KC | 1 |
| Krishnaney, AA | 1 |
| Laschtowitz, A | 1 |
| Sebode, M | 1 |
| Rattenberry, W | 1 |
| Levy, DM | 1 |
| Lin, J | 1 |
| Di Lernia, R | 1 |
| Huang, F | 1 |
| Li, S | 1 |
| Gan, X | 1 |
| Wang, R | 1 |
| Chen, Z | 1 |
| Alotaibi, WM | 1 |
| Yuan, Z | 1 |
| Liu, J | 1 |
| Liang, X | 1 |
| Lin, D | 1 |
| Mahboobi, N | 1 |
| Esmaeili, S | 1 |
| Safari, S | 1 |
| Habibollahi, P | 1 |
| Dabbagh, A | 1 |
| Alavian, SM | 1 |
| Chung, PC | 1 |
| Chiou, SC | 1 |
| Lien, JM | 1 |
| Li, AH | 1 |
| Wong, CH | 1 |
| Reich, A | 1 |
| Everding, AS | 1 |
| Bulla, M | 1 |
| Brinkmann, OA | 1 |
| Van Aken, H | 1 |
| Chidiac, EJ | 1 |
| Martin, JL | 1 |
| Yu, WF | 1 |
| Yang, LQ | 1 |
| Zhou, MT | 1 |
| Liu, ZQ | 1 |
| Li, Q | 1 |
| Jang, Y | 1 |
| Kim, I | 1 |
| Khalil, S | 1 |
| Glorimar, M | 1 |
| Tabrizi, HK | 1 |
| Fernández-Meré, LA | 1 |
| Muñoz González, F | 1 |
| Sopena Zubiria, LA | 1 |
| Alvarez Blanco, M | 1 |
| Kenna, JG | 1 |
| Jones, RM | 1 |
| Watanabe, K | 1 |
| Hatakenaka, S | 1 |
| Ikemune, K | 1 |
| Chigyo, Y | 1 |
| Kubozono, T | 1 |
| Arai, T | 1 |
| Bito, H | 2 |
| Ikeda, K | 1 |
| Russell, SC | 1 |
| Doyle, E | 1 |
| Eger, EI | 1 |
| Gong, D | 1 |
| Koblin, DD | 1 |
| Bowland, T | 1 |
| Ionescu, P | 1 |
| Laster, MJ | 1 |
| Weiskopf, RB | 1 |
| Kharasch, ED | 2 |
| Ebert, TJ | 1 |
| Frink, EJ | 1 |
| Uttamsingh, V | 1 |
| Iyer, RA | 1 |
| Baggs, RB | 1 |
| Anders, MW | 1 |
| Murat, I | 1 |
| Ghantous, HN | 1 |
| Fernando, J | 1 |
| Gandolfi, AJ | 1 |
| Brendel, K | 1 |
| Ogawa, M | 1 |
| Doi, K | 1 |
| Mitsufuji, T | 1 |
| Satoh, K | 1 |
| Takatori, T | 1 |
5 reviews available for sevoflurane and Chemical and Drug Induced Liver Injury
| Article | Year |
|---|---|
Halothane: how should it be used in a developing country?
Topics: Anesthetics, Inhalation; Attitude of Health Personnel; Chemical and Drug Induced Liver Injury; Costs | 2012 |
Desflurane vs. sevoflurane--a review.
Topics: Anesthesia, Inhalation; Anesthesiology; Anesthetics, Inhalation; Carbon Monoxide Poisoning; Central | 2004 |
The organ toxicity of inhaled anesthetics.
Topics: Anesthetics, Inhalation; Animals; Chemical and Drug Induced Liver Injury; Chloroform; Disease Models | 1995 |
Paediatric anaesthesia.
Topics: Anesthesia; Anesthesia, Local; Anesthetics, Inhalation; Chemical and Drug Induced Liver Injury; Ethe | 1997 |
[Metabolism and toxicity of anesthetics].
Topics: Anesthetics, Inhalation; Carbon Monoxide Poisoning; Chemical and Drug Induced Liver Injury; Enfluran | 1999 |
2 trials available for sevoflurane and Chemical and Drug Induced Liver Injury
| Article | Year |
|---|---|
A prospective study of the incidence of drug-induced liver injury by the modern volatile anaesthetics sevoflurane and desflurane.
Topics: Adult; Aged; Anesthetics, Inhalation; Chemical and Drug Induced Liver Injury; Cohort Studies; Desflu | 2019 |
Renal and hepatic function in surgical patients after low-flow sevoflurane or isoflurane anesthesia.
Topics: Adult; Aged; Alanine Transaminase; Anesthesia, General; Anesthetics, Inhalation; Aspartate Aminotran | 1996 |
32 other studies available for sevoflurane and Chemical and Drug Induced Liver Injury
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLI | 2010 |
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Chemical and Drug Induced Liver Injury; Da | 2011 |
Acute Fulminant Hepatic Failure Caused by Sevoflurane Linked to Influenza A.
Topics: Chemical and Drug Induced Liver Injury; Child, Preschool; Hepatitis; Humans; Influenza, Human; Liver | 2023 |
The halothane hepatitis that was not.
Topics: Anesthesia; Chemical and Drug Induced Liver Injury; Halothane; Humans; Sevoflurane | 2020 |
Propofol infusion syndrome; are high doses always required?
Topics: Adult; Anesthetics, Inhalation; Anesthetics, Intravenous; Anesthetics, Local; Bupivacaine; Chemical | 2020 |
Fatal hepatotoxicity due to sevoflurane use in a paediatric patient after aortic repair: reality or fiction? A case of pharmacovigilance.
Topics: Anesthetics, Inhalation; Chemical and Drug Induced Liver Injury; Child; Female; Humans; Infant; Meth | 2023 |
Ischemic Preconditioning Produces Comparable Protection Against Hepatic Ischemia/Reperfusion Injury Under Isoflurane and Sevoflurane Anesthesia in Rats.
Topics: Anesthetics, Inhalation; Animals; Chemical and Drug Induced Liver Injury; Ischemia; Ischemic Precond | 2017 |
Sevoflurane induces liver injury by modulating the expression of insulin-like growth factor 1 via miR-214.
Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; Chemical and Drug Induced Liver Injury; Down-Regu | 2018 |
Hepatotoxicity after sevoflurane anaesthesia: a new twist to an old story.
Topics: Anesthesia, Inhalation; Anesthetics, Inhalation; Chemical and Drug Induced Liver Injury; Humans; Lam | 2019 |
Editorial: post-operative elevation of liver enzymes and modern volatile anaesthetics-guilty as charged? Authors' reply.
Topics: Anesthetics; Chemical and Drug Induced Liver Injury; Desflurane; Humans; Incidence; Prospective Stud | 2019 |
Editorial: post-operative elevation of liver enzymes and modern volatile anaesthetics-guilty as charged?
Topics: Anesthetics; Chemical and Drug Induced Liver Injury; Desflurane; Humans; Incidence; Prospective Stud | 2019 |
Acute hepatic injury after prone surgery: was sevoflurane the cause? Comment on Br J Anaesth 2019; 122: e63-e71.
Topics: Anesthesia; Anesthesiology; Chemical and Drug Induced Liver Injury; Gastrointestinal Diseases; Human | 2019 |
Drug-induced hepatotoxicity: incidence of abnormal liver function tests consistent with volatile anaesthetic hepatitis in trauma patients.
Topics: Adult; Alanine Transaminase; Anesthesia; Anesthetics; Chemical and Drug Induced Liver Injury; Desflu | 2014 |
Propofol inhibits gap junctions by attenuating sevoflurane-induced cytotoxicity against rat liver cells in vitro.
Topics: Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Cell Line; Chemical and Drug Induced Liv | 2014 |
Severe hepatic dysfunction after sevoflurane exposure.
Topics: Anesthetics, Inhalation; Cerebellar Neoplasms; Chemical and Drug Induced Liver Injury; Child; Female | 2008 |
Serum biochemical indicators of hepatobiliary function in dogs following prolonged anaesthesia with sevoflurane or isoflurane.
Topics: Alanine Transaminase; Alkaline Phosphatase; Anesthetics, Inhalation; Animals; Aspartate Aminotransfe | 2012 |
Repeated exposure to modern volatile anaesthetics may cause chronic hepatitis as well as acute liver injury.
Topics: Acute Disease; Adult; Anesthetics; Chemical and Drug Induced Liver Injury; Female; Hepatitis; Hepati | 2012 |
Reproducible hepatic dysfunction following separate anesthesia with sevoflurane and desflurane.
Topics: Anesthetics, Inhalation; Chemical and Drug Induced Liver Injury; Desflurane; Humans; Isoflurane; Mal | 2003 |
Hepatitis after sevoflurane exposure in an infant suffering from primary hyperoxaluria type 1.
Topics: Anesthesia, General; Anesthetics, Inhalation; Biomarkers; Chemical and Drug Induced Liver Injury; He | 2004 |
[Volatile anesthetics and liver injury: a clinical update or what every anesthesiologist should know].
Topics: Anesthetics, Inhalation; Chemical and Drug Induced Liver Injury; Humans; Methyl Ethers; Occupational | 2005 |
Ca2+ cytochemical changes of hepatotoxicity caused by halothane and sevoflurane in enzyme-induced hypoxic rats.
Topics: Alanine Transaminase; Anesthetics, Inhalation; Animals; Calcium; Chemical and Drug Induced Liver Inj | 2005 |
Severe hepatotoxicity after sevoflurane anesthesia in a child with mild renal dysfunction.
Topics: Anesthesia, General; Anesthetics, Inhalation; Chemical and Drug Induced Liver Injury; Child; Female; | 2005 |
Sevoflurane-induced hepatotoxicity?
Topics: Anesthetics, Inhalation; Chemical and Drug Induced Liver Injury; Dilatation; Down Syndrome; Esophagu | 2006 |
[Sevoflurane and liver dysfunction].
Topics: Alanine Transaminase; Anesthetics, Inhalation; Aspartate Aminotransferases; Breast Implantation; Bre | 2008 |
[A case of suspected liver dysfunction induced by sevoflurane anesthesia].
Topics: Anesthesia, Inhalation; Anesthetics; Chemical and Drug Induced Liver Injury; Ethers; Hernia, Inguina | 1993 |
Dose-related biochemical markers of renal injury after sevoflurane versus desflurane anesthesia in volunteers.
Topics: Adult; Anesthesia, General; Anesthetics, Inhalation; Biomarkers; Chemical and Drug Induced Liver Inj | 1997 |
Pharmacovigilance and safety aspects of sevoflurane.
Topics: Adult; Adverse Drug Reaction Reporting Systems; Anesthetics, Inhalation; Chemical and Drug Induced L | 1997 |
Absence of biochemical evidence for renal and hepatic dysfunction after 8 hours of 1.25 minimum alveolar concentration sevoflurane anesthesia in volunteers.
Topics: Adult; Alanine Transaminase; Anesthetics, Inhalation; Body Temperature; Chemical and Drug Induced Li | 1998 |
Fate and toxicity of 2-(fluoromethoxy)-1,1,3,3,3-pentafluoro-1-propene (compound A)-derived mercapturates in male, Fischer 344 rats.
Topics: Acetylcysteine; Acyltransferases; Anesthetics, Inhalation; Animals; Biotransformation; Chemical and | 1998 |
Halothane: the last word?
Topics: Anesthetics, Inhalation; Chemical and Drug Induced Liver Injury; Child; Halothane; Humans; Infant; M | 2001 |
Sevoflurane is biotransformed by guinea pig liver slices but causes minimal cytotoxicity.
Topics: 1-Propanol; Anesthetics; Animals; Biotransformation; Chemical and Drug Induced Liver Injury; Ethers; | 1992 |
[Drug induced hepatitis following sevoflurane anesthesia in a child].
Topics: Anesthesia, Inhalation; Chemical and Drug Induced Liver Injury; Ethers; Humans; Infant; Liver; Methy | 1991 |