sevoflurane has been researched along with Cerebral Palsy in 8 studies
Sevoflurane: A non-explosive inhalation anesthetic used in the induction and maintenance of general anesthesia. It does not cause respiratory irritation and may also prevent PLATELET AGGREGATION.
sevoflurane : An ether compound having fluoromethyl and 1,1,1,3,3,3-hexafluoroisopropyl as the two alkyl groups.
Cerebral Palsy: A heterogeneous group of nonprogressive motor disorders caused by chronic brain injuries that originate in the prenatal period, perinatal period, or first few years of life. The four major subtypes are spastic, athetoid, ataxic, and mixed cerebral palsy, with spastic forms being the most common. The motor disorder may range from difficulties with fine motor control to severe spasticity (see MUSCLE SPASTICITY) in all limbs. Spastic diplegia (Little disease) is the most common subtype, and is characterized by spasticity that is more prominent in the legs than in the arms. Pathologically, this condition may be associated with LEUKOMALACIA, PERIVENTRICULAR. (From Dev Med Child Neurol 1998 Aug;40(8):520-7)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The aim of this study was to evaluate the effects of a preoperative popliteal block on sevoflurane consumption, postoperative pain, and analgesic consumption in children with cerebral palsy (CP) following lower limb surgery." | 9.24 | Popliteal block for lower limb surgery in children with cerebral palsy: effect on sevoflurane consumption and postoperative pain (a randomized, double-blinded, controlled trial). ( Akkaya, T; Bakir, M; Gonen, E; Ozkan, D, 2017) |
| " In this randomized double-blinded study, we evaluated the effects of preoperative caudal block on sevoflurane requirements in children with cerebral palsy (CP) undergoing lower limb surgery while bispectral index (BIS) values were maintained between 45 and 55." | 9.15 | Effect of caudal block on sevoflurane requirement for lower limb surgery in children with cerebral palsy. ( Chang, CH; Chun, DH; Kim, SH; Kim, TW; Kim, YM; Shin, YS, 2011) |
| "This prospective study aimed to determine the optimum end-tidal sevoflurane concentration required for immobility during botulinum toxin injection in spontaneously breathing children with cerebral palsy (CP)." | 8.12 | 50% effective concentration of sevoflurane for immobility in cerebral palsy children undergoing botulinum toxin injection. ( Baek, J; Jung, SM; Kim, K; Lee, E, 2022) |
| "We concluded that it is necessary to consider the dosage and effect mechanisms of drugs used in children with CP to prevent overuse of anesthetics and emergence of anesthesia-related complications." | 5.51 | Comparison of bispectral index values and depth of sedation during deep sedation using sevoflurane anesthesia in healthy children versus children with cerebral palsy. ( Kip, G; Onal, P; Oztas, N, 2019) |
| "Clonidine is a frequently administered alpha2-adrenergic agonist which can decrease heart rate and blood pressure." | 5.34 | Cardiac arrest in a child with cerebral palsy undergoing sevoflurane induction of anesthesia after preoperative clonidine. ( Goldfinger, MM; Tripi, PA, 2007) |
| "The aim of this study was to evaluate the effects of a preoperative popliteal block on sevoflurane consumption, postoperative pain, and analgesic consumption in children with cerebral palsy (CP) following lower limb surgery." | 5.24 | Popliteal block for lower limb surgery in children with cerebral palsy: effect on sevoflurane consumption and postoperative pain (a randomized, double-blinded, controlled trial). ( Akkaya, T; Bakir, M; Gonen, E; Ozkan, D, 2017) |
| " In this randomized double-blinded study, we evaluated the effects of preoperative caudal block on sevoflurane requirements in children with cerebral palsy (CP) undergoing lower limb surgery while bispectral index (BIS) values were maintained between 45 and 55." | 5.15 | Effect of caudal block on sevoflurane requirement for lower limb surgery in children with cerebral palsy. ( Chang, CH; Chun, DH; Kim, SH; Kim, TW; Kim, YM; Shin, YS, 2011) |
| "This prospective study aimed to determine the optimum end-tidal sevoflurane concentration required for immobility during botulinum toxin injection in spontaneously breathing children with cerebral palsy (CP)." | 4.12 | 50% effective concentration of sevoflurane for immobility in cerebral palsy children undergoing botulinum toxin injection. ( Baek, J; Jung, SM; Kim, K; Lee, E, 2022) |
| "We concluded that it is necessary to consider the dosage and effect mechanisms of drugs used in children with CP to prevent overuse of anesthetics and emergence of anesthesia-related complications." | 1.51 | Comparison of bispectral index values and depth of sedation during deep sedation using sevoflurane anesthesia in healthy children versus children with cerebral palsy. ( Kip, G; Onal, P; Oztas, N, 2019) |
| "Clonidine is a frequently administered alpha2-adrenergic agonist which can decrease heart rate and blood pressure." | 1.34 | Cardiac arrest in a child with cerebral palsy undergoing sevoflurane induction of anesthesia after preoperative clonidine. ( Goldfinger, MM; Tripi, PA, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (12.50) | 18.2507 |
| 2000's | 3 (37.50) | 29.6817 |
| 2010's | 3 (37.50) | 24.3611 |
| 2020's | 1 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| Kim, K | 1 |
| Lee, E | 1 |
| Jung, SM | 1 |
| Baek, J | 1 |
| Onal, P | 1 |
| Oztas, N | 1 |
| Kip, G | 1 |
| Ozkan, D | 1 |
| Gonen, E | 1 |
| Akkaya, T | 1 |
| Bakir, M | 1 |
| Abdallah, C | 1 |
| Hannallah, R | 1 |
| Kim, SH | 1 |
| Chun, DH | 1 |
| Chang, CH | 1 |
| Kim, TW | 1 |
| Kim, YM | 1 |
| Shin, YS | 1 |
| Loyola-Rodriguez, JP | 1 |
| Aguilera-Morelos, AA | 1 |
| Santos-Diaz, MA | 1 |
| Zavala-Alonso, V | 1 |
| Davila-Perez, C | 1 |
| Olvera-Delgado, H | 1 |
| Patiño-Marin, N | 1 |
| De Leon-Cobian, I | 1 |
| Goldfinger, MM | 1 |
| Tripi, PA | 1 |
| Ogasawara, H | 1 |
| Shimodate, Y | 1 |
| Isozaki, K | 1 |
| Matsuki, A | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| 50% Effective Concentration of Sevoflurane for Immobility in Cerebral Palsy Children Undergoing Botulinum Toxin Injection[NCT03553446] | 23 participants (Actual) | Interventional | 2018-07-29 | Completed | |||
| "Postoperative Pain Management in Pediatric Patients With Cerebral Palsy - Comparative Observational Study"[NCT05252650] | 130 participants (Anticipated) | Observational | 2022-02-15 | Recruiting | |||
| Popliteal Block for Postoperative Pain in Knee-ankle Soft Tissue Surgery in Cerebral Palsy[NCT02507700] | 60 participants (Actual) | Interventional | 2015-06-30 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 trials available for sevoflurane and Cerebral Palsy
| Article | Year |
|---|---|
Popliteal block for lower limb surgery in children with cerebral palsy: effect on sevoflurane consumption and postoperative pain (a randomized, double-blinded, controlled trial).
Topics: Acetaminophen; Adolescent; Anesthesia, General; Bupivacaine; Cerebral Palsy; Child; Child, Preschool | 2017 |
Popliteal block for lower limb surgery in children with cerebral palsy: effect on sevoflurane consumption and postoperative pain (a randomized, double-blinded, controlled trial).
Topics: Acetaminophen; Adolescent; Anesthesia, General; Bupivacaine; Cerebral Palsy; Child; Child, Preschool | 2017 |
Popliteal block for lower limb surgery in children with cerebral palsy: effect on sevoflurane consumption and postoperative pain (a randomized, double-blinded, controlled trial).
Topics: Acetaminophen; Adolescent; Anesthesia, General; Bupivacaine; Cerebral Palsy; Child; Child, Preschool | 2017 |
Popliteal block for lower limb surgery in children with cerebral palsy: effect on sevoflurane consumption and postoperative pain (a randomized, double-blinded, controlled trial).
Topics: Acetaminophen; Adolescent; Anesthesia, General; Bupivacaine; Cerebral Palsy; Child; Child, Preschool | 2017 |
Effect of caudal block on sevoflurane requirement for lower limb surgery in children with cerebral palsy.
Topics: Achilles Tendon; Anesthesia, Caudal; Anesthesia, General; Anesthesia, Inhalation; Anesthetics, Inhal | 2011 |
6 other studies available for sevoflurane and Cerebral Palsy
| Article | Year |
|---|---|
50% effective concentration of sevoflurane for immobility in cerebral palsy children undergoing botulinum toxin injection.
Topics: Anesthetics, Inhalation; Botulinum Toxins, Type A; Cerebral Palsy; Child; Humans; Methyl Ethers; Oxy | 2022 |
Comparison of bispectral index values and depth of sedation during deep sedation using sevoflurane anesthesia in healthy children versus children with cerebral palsy.
Topics: Anesthesia, Dental; Anesthetics, Inhalation; Cerebral Palsy; Child; Child, Preschool; Consciousness; | 2019 |
Dystonic reaction after Botox injection under nitrous oxide/oxygen and sevoflurane anesthesia.
Topics: Adolescent; Anesthesia, Inhalation; Anesthetics, Inhalation; Botulinum Toxins, Type A; Cerebral Pals | 2009 |
Oral rehabilitation under dental general anesthesia, conscious sedation, and conventional techniques in patients affected by cerebral palsy.
Topics: Adolescent; Adolescent Behavior; Adult; Anesthesia Recovery Period; Anesthesia, Dental; Anesthesia, | 2004 |
Cardiac arrest in a child with cerebral palsy undergoing sevoflurane induction of anesthesia after preoperative clonidine.
Topics: Adrenergic alpha-Agonists; Anesthesia, General; Anesthetics, Inhalation; Cerebral Palsy; Child, Pres | 2007 |
[Sevoflurane anesthesia for a patient with cerebral palsy].
Topics: Adult; Anesthetics; Cerebral Palsy; Ethers; Humans; Male; Methyl Ethers; Retinal Detachment; Sevoflu | 1990 |