sevoflurane has been researched along with Cardiac Diseases in 22 studies
Sevoflurane: A non-explosive inhalation anesthetic used in the induction and maintenance of general anesthesia. It does not cause respiratory irritation and may also prevent PLATELET AGGREGATION.
sevoflurane : An ether compound having fluoromethyl and 1,1,1,3,3,3-hexafluoroisopropyl as the two alkyl groups.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Sevoflurane is associated with less tachycardia and coronary vasodilation than isoflurane and thus might be associated with less myocardial ischemia." | 9.08 | Myocardial ischemia and adverse cardiac outcomes in cardiac patients undergoing noncardiac surgery with sevoflurane and isoflurane. Sevoflurane Ischemia Study Group. ( Ebert, TJ; Kharasch, ED; Muzi, M; Rooke, GA; Shroff, A, 1997) |
| "A randomised controlled study in Caen University Hospital Centre, investigated whether the clinical cardio protective effects of administration sevoflurane before cardiopulmonary bypass during coronary artery bypass graft surgery (CABG) could translate into protected atrial trabeculae contractility against hypoxia-reoxygenation in vitro." | 5.27 | Sevoflurane-induced cardioprotection in coronary artery bypass graft surgery: Randomised trial with clinical and ex-vivo endpoints. ( Gérard, JL; Hanouz, JL; Lemoine, S; Zhu, L, 2018) |
| "To compare the safety of sevoflurane anesthesia with laryngeal mask and tracheal intubation in cesarean section in women with heart disease." | 5.27 | [Application of sevoflurane and laryngeal mask in cesarean section in women with heart disease]. ( Ma, J; Wang, S; Wang, ZP; Wei, JF; Xu, JD; Yu, LN, 2018) |
| "Sevoflurane is associated with less tachycardia and coronary vasodilation than isoflurane and thus might be associated with less myocardial ischemia." | 5.08 | Myocardial ischemia and adverse cardiac outcomes in cardiac patients undergoing noncardiac surgery with sevoflurane and isoflurane. Sevoflurane Ischemia Study Group. ( Ebert, TJ; Kharasch, ED; Muzi, M; Rooke, GA; Shroff, A, 1997) |
| "Sevoflurane, a widely used inhalation anesthetic, has been shown to be cardioprotective in individuals with sepsis and myocardial dysfunction." | 4.12 | Molecular Mechanism of Sevoflurane Preconditioning Based on Whole-transcriptome Sequencing of Lipopolysaccharide-induced Cardiac Dysfunction in Mice. ( Li, H; Li, J; Li, S; Li, Y; Xie, J, 2022) |
| "Sevoflurane may inhibit platelet activation, raising the possibility that administering it during CPB may reduce blood loss." | 2.82 | Low-Dose Sevoflurane May Reduce Blood Loss and Need for Blood Products After Cardiac Surgery: A Prospective, Randomized Pilot Study. ( Chen, H; Du, L; Li, J; Liu, T; Luo, M; Qin, Z; Tan, Z; Xiong, J; Zhou, J; Zhou, L, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (4.55) | 18.2507 |
| 2000's | 8 (36.36) | 29.6817 |
| 2010's | 12 (54.55) | 24.3611 |
| 2020's | 1 (4.55) | 2.80 |
| Authors | Studies |
|---|---|
| Xie, J | 1 |
| Li, H | 1 |
| Li, S | 1 |
| Li, J | 2 |
| Li, Y | 1 |
| Lemoine, S | 1 |
| Zhu, L | 1 |
| Gérard, JL | 1 |
| Hanouz, JL | 1 |
| Wang, ZP | 1 |
| Ma, J | 1 |
| Wang, S | 1 |
| Yu, LN | 1 |
| Wei, JF | 1 |
| Xu, JD | 1 |
| Zhou, HM | 1 |
| Ling, XY | 1 |
| Ni, YJ | 1 |
| Wu, C | 1 |
| Zhu, ZP | 1 |
| Banchs, R | 1 |
| Lerman, J | 1 |
| Wald, SH | 1 |
| Bonvini, JM | 1 |
| Beck-Schimmer, B | 1 |
| Kuhn, SJ | 1 |
| Graber, SM | 1 |
| Neff, TA | 1 |
| Schläpfer, M | 1 |
| Li, F | 1 |
| Yuan, Y | 1 |
| Yu, QB | 1 |
| Li, HM | 1 |
| Li, LL | 1 |
| Wang, SY | 1 |
| Wu, YB | 1 |
| Tan, Z | 1 |
| Zhou, L | 1 |
| Qin, Z | 1 |
| Luo, M | 1 |
| Chen, H | 1 |
| Xiong, J | 1 |
| Liu, T | 1 |
| Du, L | 1 |
| Zhou, J | 1 |
| Conghai, F | 1 |
| Fengchao, Z | 1 |
| Chengjing, S | 1 |
| Cheng, W | 1 |
| Yunji, W | 1 |
| Xiaobo, L | 1 |
| Wu, Y | 1 |
| Wang, J | 2 |
| Yu, X | 1 |
| Li, D | 1 |
| Han, X | 1 |
| Fan, L | 1 |
| Bouwman, RA | 2 |
| Vreden, MJ | 1 |
| Hamdani, N | 1 |
| Wassenaar, LE | 1 |
| Smeding, L | 1 |
| Loer, SA | 1 |
| Stienen, GJ | 1 |
| Lamberts, RR | 1 |
| Zheng, H | 1 |
| Chen, CL | 1 |
| Lu, W | 1 |
| Zhang, YQ | 1 |
| Julier, K | 2 |
| da Silva, R | 1 |
| Garcia, C | 2 |
| Bestmann, L | 3 |
| Frascarolo, P | 1 |
| Zollinger, A | 3 |
| Chassot, PG | 1 |
| Schmid, ER | 1 |
| Turina, MI | 1 |
| von Segesser, LK | 2 |
| Pasch, T | 2 |
| Spahn, DR | 2 |
| Zaugg, M | 3 |
| Müllenheim, J | 1 |
| Ebel, D | 1 |
| Bauer, M | 1 |
| Otto, F | 1 |
| Heinen, A | 1 |
| Frässdorf, J | 1 |
| Preckel, B | 1 |
| Schlack, W | 1 |
| de Ruijter, W | 1 |
| Musters, RJP | 1 |
| Boer, C | 2 |
| Stienen, GJM | 1 |
| Simonides, WS | 1 |
| de Lange, JJ | 2 |
| Musters, RJ | 1 |
| van Beek-Harmsen, BJ | 1 |
| De Hert, SG | 1 |
| Van der Linden, PJ | 1 |
| Cromheecke, S | 1 |
| Meeus, R | 1 |
| Nelis, A | 1 |
| Van Reeth, V | 1 |
| ten Broecke, PW | 1 |
| De Blier, IG | 1 |
| Stockman, BA | 1 |
| Rodrigus, IE | 1 |
| Djalali, AG | 1 |
| Sadovnikoff, N | 1 |
| Lucchinetti, E | 1 |
| Hofer, C | 1 |
| Hersberger, M | 1 |
| Feng, J | 1 |
| Zhu, M | 1 |
| Furrer, L | 1 |
| Schaub, MC | 1 |
| Tavakoli, R | 1 |
| Genoni, M | 1 |
| Ebert, TJ | 1 |
| Kharasch, ED | 1 |
| Rooke, GA | 1 |
| Shroff, A | 1 |
| Muzi, M | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Comparison Between the Effect of Target-controlled Infusion of Propofol and Sevoflurane as Maintenance of Anesthesia to Intraoperative Hemodynamic Profile of Renal Transplant Recipient[NCT03214653] | 23 participants (Actual) | Interventional | 2017-07-01 | Completed | |||
| A Comparison of Myocardial Protection Using Preconditioning With Sevoflurane Against High Thoracic Epidural Analgesia for CABG Surgery[NCT00244283] | Phase 4 | 150 participants | Interventional | 2006-01-31 | Not yet recruiting | ||
| Optimierung Der Kardioprotektion Durch Inhalative Anästhetika Eine Untersuchung Bei Patienten Mit Diabetes Mellitus während Off-pump Herzchirurgie[NCT02407626] | 2 participants (Actual) | Interventional | 2015-09-30 | Terminated (stopped due to Very low patient recruitment, changed insurance requirements) | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for sevoflurane and Cardiac Diseases
| Article | Year |
|---|---|
Meta-analysis of the cardioprotective effect of sevoflurane versus propofol during cardiac surgery.
Topics: Anesthetics, Inhalation; Anesthetics, Intravenous; Atrial Fibrillation; Cardiac Output; Cardiac Surg | 2015 |
Sevoflurane downregulates interleukin-6 and interleukin-8 levels in patients after cardiopulmonary bypass surgery: a meta-analysis.
Topics: Anti-Inflammatory Agents; Cardiopulmonary Bypass; Case-Control Studies; Down-Regulation; Heart Disea | 2015 |
10 trials available for sevoflurane and Cardiac Diseases
| Article | Year |
|---|---|
Sevoflurane-induced cardioprotection in coronary artery bypass graft surgery: Randomised trial with clinical and ex-vivo endpoints.
Topics: Aged; Aged, 80 and over; Anesthetics, Inhalation; Cardiotonic Agents; Coronary Artery Bypass; Female | 2018 |
[Application of sevoflurane and laryngeal mask in cesarean section in women with heart disease].
Topics: Anesthesia; Blood Pressure; Cesarean Section; Female; Heart Diseases; Heart Rate; Humans; Infant, Ne | 2018 |
Late Post-Conditioning with Sevoflurane after Cardiac Surgery--Are Surrogate Markers Associated with Clinical Outcome?
Topics: Aged; Anesthetics, Inhalation; Cardiac Surgical Procedures; Female; Follow-Up Studies; Heart Disease | 2015 |
Low-Dose Sevoflurane May Reduce Blood Loss and Need for Blood Products After Cardiac Surgery: A Prospective, Randomized Pilot Study.
Topics: Administration, Inhalation; Adult; Blood Loss, Surgical; Dose-Response Relationship, Drug; Erythrocy | 2016 |
Sevoflurane at 1 MAC provides optimal myocardial protection during off-pump CABG.
Topics: Administration, Inhalation; Adult; Aged; Analysis of Variance; Anesthetics, Inhalation; Biomarkers; | 2013 |
Preconditioning by sevoflurane decreases biochemical markers for myocardial and renal dysfunction in coronary artery bypass graft surgery: a double-blinded, placebo-controlled, multicenter study.
Topics: Adult; Aged; Aged, 80 and over; Anesthesia, Inhalation; Anesthetics, Inhalation; Biomarkers; Coronar | 2003 |
Preconditioning by sevoflurane decreases biochemical markers for myocardial and renal dysfunction in coronary artery bypass graft surgery: a double-blinded, placebo-controlled, multicenter study.
Topics: Adult; Aged; Aged, 80 and over; Anesthesia, Inhalation; Anesthetics, Inhalation; Biomarkers; Coronar | 2003 |
Preconditioning by sevoflurane decreases biochemical markers for myocardial and renal dysfunction in coronary artery bypass graft surgery: a double-blinded, placebo-controlled, multicenter study.
Topics: Adult; Aged; Aged, 80 and over; Anesthesia, Inhalation; Anesthetics, Inhalation; Biomarkers; Coronar | 2003 |
Preconditioning by sevoflurane decreases biochemical markers for myocardial and renal dysfunction in coronary artery bypass graft surgery: a double-blinded, placebo-controlled, multicenter study.
Topics: Adult; Aged; Aged, 80 and over; Anesthesia, Inhalation; Anesthetics, Inhalation; Biomarkers; Coronar | 2003 |
Cardioprotective properties of sevoflurane in patients undergoing coronary surgery with cardiopulmonary bypass are related to the modalities of its administration.
Topics: Aged; Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthetics, Inhalation; Anesthetics, Intrave | 2004 |
Preconditioning with sevoflurane decreases PECAM-1 expression and improves one-year cardiovascular outcome in coronary artery bypass graft surgery.
Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Inhalation; Cardiotonic Agents; Coronary Artery Bypass; | 2005 |
Gene regulatory control of myocardial energy metabolism predicts postoperative cardiac function in patients undergoing off-pump coronary artery bypass graft surgery: inhalational versus intravenous anesthetics.
Topics: Aged; Aged, 80 and over; Anesthetics, Inhalation; Anesthetics, Intravenous; Biomarkers; Coronary Art | 2007 |
Myocardial ischemia and adverse cardiac outcomes in cardiac patients undergoing noncardiac surgery with sevoflurane and isoflurane. Sevoflurane Ischemia Study Group.
Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Inhalation; Coronary Disease; Ethers; Female; Heart Dis | 1997 |
10 other studies available for sevoflurane and Cardiac Diseases
| Article | Year |
|---|---|
Molecular Mechanism of Sevoflurane Preconditioning Based on Whole-transcriptome Sequencing of Lipopolysaccharide-induced Cardiac Dysfunction in Mice.
Topics: Animals; Heart Diseases; Lipopolysaccharides; Mice; MicroRNAs; Mitogen-Activated Protein Kinases; Ne | 2022 |
Pre-cardiopulmonary bypass administration of dexmedetomidine decreases cardiac troponin I level following cardiac surgery with sevoflurane postconditioning.
Topics: Analgesics, Non-Narcotic; Anesthetics, Inhalation; Cardiopulmonary Bypass; Dexmedetomidine; Female; | 2019 |
The use of nitrous oxide as an adjuvant for inhalation inductions with sevoflurane: a pro-con debate.
Topics: Adolescent; Anesthetics, Inhalation; Apoptosis; Child; Child, Preschool; Drug Interactions; Environm | 2013 |
The Optimum Level of Sevoflurane in Pediatric Echocardiography.
Topics: Anesthetics, Inhalation; Blood Pressure; Child, Preschool; Echocardiography; Female; Heart Diseases; | 2015 |
Sevoflurane ameliorates doxorubicin-induced myocardial injury by affecting the phosphorylation states of proteins in PI3K/Akt/mTOR signaling pathway.
Topics: Animals; Apoptosis; Cardiotoxicity; Cell Line; Creatine Kinase, MB Form; Cytoprotection; Disease Mod | 2017 |
Effect of bupivacaine on sevoflurane-induced preconditioning in isolated rat hearts.
Topics: Anesthetics, Inhalation; Anesthetics, Local; Animals; Bupivacaine; Heart; Heart Diseases; In Vitro T | 2010 |
Sevoflurane confers additional cardioprotection after ischemic late preconditioning in rabbits.
Topics: Anesthetics, Inhalation; Animals; ATP-Binding Cassette Transporters; Blood Pressure; Coronary Vessel | 2003 |
The cardioprotective effect of sevoflurane depends on protein kinase C activation, opening of mitochondrial K(+)(ATP) channels, and the production of reactive oxygen species.
Topics: Anesthetics, Inhalation; Animals; ATP-Binding Cassette Transporters; Enzyme Activation; Enzyme Inhib | 2003 |
Reactive oxygen species precede protein kinase C-delta activation independent of adenosine triphosphate-sensitive mitochondrial channel opening in sevoflurane-induced cardioprotection.
Topics: Anesthetics, Inhalation; Animals; Enzyme Activation; Heart; Heart Diseases; Image Processing, Comput | 2004 |
Cardioprotective properties of sevoflurane in patients undergoing coronary surgery with cardiopulmonary bypass are related to the modalities of its administration.
Topics: Anesthetics, Inhalation; Cardiopulmonary Bypass; Heart Diseases; Humans; Methyl Ethers; Protective A | 2005 |