sevoflurane has been researched along with Brain Ischemia in 62 studies
Sevoflurane: A non-explosive inhalation anesthetic used in the induction and maintenance of general anesthesia. It does not cause respiratory irritation and may also prevent PLATELET AGGREGATION.
sevoflurane : An ether compound having fluoromethyl and 1,1,1,3,3,3-hexafluoroisopropyl as the two alkyl groups.
Brain Ischemia: Localized reduction of blood flow to brain tissue due to arterial obstruction or systemic hypoperfusion. This frequently occurs in conjunction with brain hypoxia (HYPOXIA, BRAIN). Prolonged ischemia is associated with BRAIN INFARCTION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We aimed to study the influence of sevoflurane on the nucleotide-binding domain and Leucine-rich repeat protein 3 (NLRP3) pathways in rats with cerebral ischemia/reperfusion (I/R) injury." | 8.31 | Sevoflurane preconditioning improves neuroinflammation in cerebral ischemia/reperfusion induced rats through ROS-NLRP3 pathway. ( Shang, S; Shao, W; Sun, F; Wang, Z; Yi, X; Yu, J; Yu, L; Zhu, Y, 2023) |
| "To determine whether sevoflurane postconditioning protects against cerebral ischemia reperfusion (I/R) injury and its potential mechanism, we employed bioinformatic analysis, neurological assessments, and western blot analysis, as well as triphenyl tetrazolium chloride, hematoxylin and eosin, Nissl, and immunofluorescence staining." | 8.12 | Sevoflurane postconditioning ameliorates cerebral ischemia-reperfusion injury in rats via TLR4/MyD88/TRAF6 signaling pathway. ( Chi, F; Hou, Z; Li, Y; Ma, L; Wang, Q; Zhao, Z, 2022) |
| "Sevoflurane (SEV) has been reported to be an effective neuroprotective agent for cerebral ischemia/reperfusion injury (CIRI)." | 8.02 | Sevoflurane protects against cerebral ischemia/reperfusion injury via microrna-30c-5p modulating homeodomain-interacting protein kinase 1. ( Deng, M; Li, G; Qu, Y; Su, G, 2021) |
| "To investigate the expression of miR-203 by sevoflurane treatment and its effect on neuroinflammation induced by cerebral ischemia-reperfusion." | 7.96 | Sevoflurane Post-treatment Upregulated miR-203 Expression to Attenuate Cerebral Ischemia-Reperfusion-Induced Neuroinflammation by Targeting MyD88. ( Chen, H; Gu, C; Zhong, H, 2020) |
| "Objective To determine whether regulatory T cells (Tregs) are involved in sevoflurane preconditioning-induced brain protection against cerebral ischemia/reperfusion injury." | 7.91 | [Regulatory T cells are involved in sevoflurane preconditioning-induced mouse brain protection against cerebral ischemia injury]. ( Chen, J; Jia, W; Wang, S; Wei, H; Zhen, L, 2019) |
| "The aim of the study was to investigate the anti-inflammatory effect of sevoflurane post-conditioning on cerebral ischemia-reperfusion injury in rats." | 7.88 | Effects of sevoflurane post-conditioning in cerebral ischemia-reperfusion injury via TLR4/NF-κB pathway in rats. ( Ding, YB; Jin, FYJ; Li, KZ; Li, T; Ma, JH; Pan, WZ; Qiao, LY; Shi, CX, 2018) |
| "Potential additive effects of estrogens and sevoflurane against cerebral infarction after transient or permanent middle cerebral artery occlusion (MCAO) have not been addressed." | 7.83 | Protective effects of estrogen combined with sevoflurane in an experimental model of cerebral infarction and focal cerebral ischemia-reperfusion injury. ( Liu, JJ; Pan, SY, 2016) |
| "Postconditioning with sevoflurane has been shown to protect against focal cerebral ischemia and reperfusion injury." | 7.81 | Postconditioning with sevoflurane protects against focal cerebral ischemia and reperfusion injury involving mitochondrial ATP-dependent potassium channel and mitochondrial permeability transition pore. ( Liu, XZ; Wang, JK; Wu, HF; Yang, B; Zhou, H, 2015) |
| "These findings show that sevoflurane administration after ischemia does not provide neuroprotection in rats subjected to incomplete cerebral ischemia." | 7.76 | Sevoflurane-induced post-conditioning has no beneficial effects on neuroprotection after incomplete cerebral ischemia in rats. ( Choi, JH; DO, HS; Jee, DL; Kim, YW; Lee, DH; Lee, HM; Lee, SR; Park, SJ, 2010) |
| "Sevoflurane pretreatment can protect neuron on ischemia-reperfusion injury by attenuating neuronal apoptosis in rats." | 7.75 | [Protective effects of sevoflurane preconditioning on cerebral ischemia-reperfusion injury in rats]. ( Hu, ZY; Lin, HF; Zhu, ZR, 2009) |
| "The volatile anesthetic sevoflurane exhibits neuroprotective properties when assessed for motor function and histopathology after cerebral ischemia in rats." | 7.75 | Effects of sevoflurane on cognitive deficit, motor function, and histopathology after cerebral ischemia in rats. ( Blobner, M; Eberspächer, E; Eckel, B; Engelhard, K; Hoffman, WE; Müller, K; Werner, C, 2009) |
| "In this model of transient focal cerebral ischemia, sevoflurane preconditioning induced effective but transient neuroprotective effects." | 7.75 | Sevoflurane preconditioning against focal cerebral ischemia: inhibition of apoptosis in the face of transient improvement of neurological outcome. ( Bruder, NJ; Codaccioni, JL; Guillet, BA; Moubarik, C; Pisano, PS; Velly, LJ, 2009) |
| "4% sevoflurane, cerebral ischemia caused mild neuronal damage (HE-index of 0." | 7.74 | Sevoflurane affects neurogenesis after forebrain ischemia in rats. ( Eberspächer, E; Engelhard, K; Hollweck, R; Hutzler, P; Kluge, J; Kochs, E; Werner, C; Winkelheide, U; Winkler, J, 2007) |
| " Sevoflurane, a volatile anesthetic agent, improved neuronal recovery subsequent to 10 min of global cerebral ischemia when it was present for 1 h before the ischemia." | 7.74 | Sevoflurane immediate preconditioning alters hypoxic membrane potential changes in rat hippocampal slices and improves recovery of CA1 pyramidal cells after hypoxia and global cerebral ischemia. ( Cottrell, JE; Kass, IS; Lei, B; Meng, F; Popp, S; Wang, J, 2007) |
| "We compared the postischemic cerebral protective effects of sevoflurane and desflurane in rats with incomplete cerebral ischemia." | 7.73 | Effects of sevoflurane and desflurane in CA1 after incomplete cerebral ischemia in rats. ( Alici, HA; Cesur, M; Dogan, N; Erdem, AF; Erdogan, F; Kursad, H; Yuksek, MS, 2005) |
| "During incomplete cerebral ischemia, the neuroprotective anesthetics sevoflurane and propofol suppressed cerebral increases in norepinephrine and glutamate concentrations." | 7.72 | The effect of sevoflurane and propofol on cerebral neurotransmitter concentrations during cerebral ischemia in rats. ( Blobner, M; Engelhard, K; Hoffman, WE; Kochs, E; Matthes, B; Werner, C, 2003) |
| " We evaluated whether the effect of sevoflurane is similar to that of isoflurane or halothane on brain energy metabolism after cerebral ischemia followed by reperfusion using 31P-magnetic resonance spectroscopy." | 7.69 | The effects of sevoflurane on recovery of brain energy metabolism after cerebral ischemia in the rat: a comparison with isoflurane and halothane. ( Fujise, Y; Ikeda, K; Moriwaki, G; Nakajima, Y, 1997) |
| "We examined the effects of sevoflurane anesthesia with hypothermia on ischemic brain cellular respiration using Wistar strain rats." | 7.68 | [The effects of sevoflurane anesthesia with hypothermia on ischemic brain cellular respiration]. ( Kubota, N; Matsuo, R; Shibata, T; Takahashi, K; Yokoyama, H, 1993) |
| "Sevoflurane was discontinued and anesthesia continued with fentanyl/nitrous oxide for an additional 100 minutes." | 5.42 | Preischemic Administration of Sevoflurane Does not Exert Dose-dependent Effects on the Outcome of Severe Forebrain Ischemia in Rats. ( Kanazawa, K; Miura, Y; Nasu, I, 2015) |
| "Obesity is associated with increased infarct volumes and adverse outcomes following ischemic stroke." | 5.40 | Sevoflurane postconditioning against cerebral ischemic neuronal injury is abolished in diet-induced obesity: role of brain mitochondrial KATP channels. ( Chen, Y; Fang, X; Jiang, Y; Xu, J; Yang, Z; Zhang, Y, 2014) |
| "Focal cerebral ischemia was performed via 1h of middle cerebral artery occlusion (MCAO) followed by reperfusion." | 5.39 | Preconditioning with sevoflurane ameliorates spatial learning and memory deficit after focal cerebral ischemia-reperfusion in rats. ( Hu, X; Li, W; Li, Y; Liu, J; Zhang, Y, 2013) |
| "Sevoflurane pretreatment also suppressed the activation of astrocytes and microglias in ipsilateral cortex and corpus callosum." | 5.37 | Sevoflurane preconditioning protects blood-brain-barrier against brain ischemia. ( Chen, J; Chu, M; Gan, Y; Gao, H; Gao, Y; Li, P; Liang, W; Lu, S; Shi, H; Wang, H; Yu, Q, 2011) |
| "Various experimental studies have reported neuroprotective effects of sevoflurane postconditioning against cerebral ischemia-reperfusion injury." | 5.34 | Effect of Sevoflurane Postconditioning on the Incidence of Symptomatic Cerebral Hyperperfusion After Revascularization Surgery in Adult Patients with Moyamoya Disease. ( Cho, WS; Choi, H; Kim, JE; Lee, HC; Oh, H; Park, HP; Park, JW; Yoon, HK, 2020) |
| "88 MAC sevoflurane anesthesia in patients with ischemic cerebrovascular disease." | 5.07 | Effects of sevoflurane on cerebral circulation and metabolism in patients with ischemic cerebrovascular disease. ( Hayashi, Y; Kitaguchi, K; Kuro, M; Nakajima, T; Ohsumi, H, 1993) |
| "We aimed to study the influence of sevoflurane on the nucleotide-binding domain and Leucine-rich repeat protein 3 (NLRP3) pathways in rats with cerebral ischemia/reperfusion (I/R) injury." | 4.31 | Sevoflurane preconditioning improves neuroinflammation in cerebral ischemia/reperfusion induced rats through ROS-NLRP3 pathway. ( Shang, S; Shao, W; Sun, F; Wang, Z; Yi, X; Yu, J; Yu, L; Zhu, Y, 2023) |
| "To determine whether sevoflurane postconditioning protects against cerebral ischemia reperfusion (I/R) injury and its potential mechanism, we employed bioinformatic analysis, neurological assessments, and western blot analysis, as well as triphenyl tetrazolium chloride, hematoxylin and eosin, Nissl, and immunofluorescence staining." | 4.12 | Sevoflurane postconditioning ameliorates cerebral ischemia-reperfusion injury in rats via TLR4/MyD88/TRAF6 signaling pathway. ( Chi, F; Hou, Z; Li, Y; Ma, L; Wang, Q; Zhao, Z, 2022) |
| "Sevoflurane (SEV) has been reported to be an effective neuroprotective agent for cerebral ischemia/reperfusion injury (CIRI)." | 4.02 | Sevoflurane protects against cerebral ischemia/reperfusion injury via microrna-30c-5p modulating homeodomain-interacting protein kinase 1. ( Deng, M; Li, G; Qu, Y; Su, G, 2021) |
| "To investigate the expression of miR-203 by sevoflurane treatment and its effect on neuroinflammation induced by cerebral ischemia-reperfusion." | 3.96 | Sevoflurane Post-treatment Upregulated miR-203 Expression to Attenuate Cerebral Ischemia-Reperfusion-Induced Neuroinflammation by Targeting MyD88. ( Chen, H; Gu, C; Zhong, H, 2020) |
| "Objective To determine whether regulatory T cells (Tregs) are involved in sevoflurane preconditioning-induced brain protection against cerebral ischemia/reperfusion injury." | 3.91 | [Regulatory T cells are involved in sevoflurane preconditioning-induced mouse brain protection against cerebral ischemia injury]. ( Chen, J; Jia, W; Wang, S; Wei, H; Zhen, L, 2019) |
| "The aim of the study was to investigate the anti-inflammatory effect of sevoflurane post-conditioning on cerebral ischemia-reperfusion injury in rats." | 3.88 | Effects of sevoflurane post-conditioning in cerebral ischemia-reperfusion injury via TLR4/NF-κB pathway in rats. ( Ding, YB; Jin, FYJ; Li, KZ; Li, T; Ma, JH; Pan, WZ; Qiao, LY; Shi, CX, 2018) |
| " It has demonstrated that sevoflurane has neuroprotective effects against ischemic stroke, but its effects on ischemia-induced formation of astrogliosis and glial scar are unknown." | 3.85 | Sevoflurane postconditioning attenuates reactive astrogliosis and glial scar formation after ischemia-reperfusion brain injury. ( Gao, X; Kent, TA; Li, W; Ni, Y; Qiao, SG; Wang, C; Xu, XX; Zhang, HL; Zhu, YM, 2017) |
| "Potential additive effects of estrogens and sevoflurane against cerebral infarction after transient or permanent middle cerebral artery occlusion (MCAO) have not been addressed." | 3.83 | Protective effects of estrogen combined with sevoflurane in an experimental model of cerebral infarction and focal cerebral ischemia-reperfusion injury. ( Liu, JJ; Pan, SY, 2016) |
| "Postconditioning with sevoflurane has been shown to protect against focal cerebral ischemia and reperfusion injury." | 3.81 | Postconditioning with sevoflurane protects against focal cerebral ischemia and reperfusion injury involving mitochondrial ATP-dependent potassium channel and mitochondrial permeability transition pore. ( Liu, XZ; Wang, JK; Wu, HF; Yang, B; Zhou, H, 2015) |
| "These findings show that sevoflurane administration after ischemia does not provide neuroprotection in rats subjected to incomplete cerebral ischemia." | 3.76 | Sevoflurane-induced post-conditioning has no beneficial effects on neuroprotection after incomplete cerebral ischemia in rats. ( Choi, JH; DO, HS; Jee, DL; Kim, YW; Lee, DH; Lee, HM; Lee, SR; Park, SJ, 2010) |
| "Sevoflurane pretreatment can protect neuron on ischemia-reperfusion injury by attenuating neuronal apoptosis in rats." | 3.75 | [Protective effects of sevoflurane preconditioning on cerebral ischemia-reperfusion injury in rats]. ( Hu, ZY; Lin, HF; Zhu, ZR, 2009) |
| "The volatile anesthetic sevoflurane exhibits neuroprotective properties when assessed for motor function and histopathology after cerebral ischemia in rats." | 3.75 | Effects of sevoflurane on cognitive deficit, motor function, and histopathology after cerebral ischemia in rats. ( Blobner, M; Eberspächer, E; Eckel, B; Engelhard, K; Hoffman, WE; Müller, K; Werner, C, 2009) |
| "In this model of transient focal cerebral ischemia, sevoflurane preconditioning induced effective but transient neuroprotective effects." | 3.75 | Sevoflurane preconditioning against focal cerebral ischemia: inhibition of apoptosis in the face of transient improvement of neurological outcome. ( Bruder, NJ; Codaccioni, JL; Guillet, BA; Moubarik, C; Pisano, PS; Velly, LJ, 2009) |
| " Sevoflurane, a volatile anesthetic agent, improved neuronal recovery subsequent to 10 min of global cerebral ischemia when it was present for 1 h before the ischemia." | 3.74 | Sevoflurane immediate preconditioning alters hypoxic membrane potential changes in rat hippocampal slices and improves recovery of CA1 pyramidal cells after hypoxia and global cerebral ischemia. ( Cottrell, JE; Kass, IS; Lei, B; Meng, F; Popp, S; Wang, J, 2007) |
| "4% sevoflurane, cerebral ischemia caused mild neuronal damage (HE-index of 0." | 3.74 | Sevoflurane affects neurogenesis after forebrain ischemia in rats. ( Eberspächer, E; Engelhard, K; Hollweck, R; Hutzler, P; Kluge, J; Kochs, E; Werner, C; Winkelheide, U; Winkler, J, 2007) |
| "We compared the postischemic cerebral protective effects of sevoflurane and desflurane in rats with incomplete cerebral ischemia." | 3.73 | Effects of sevoflurane and desflurane in CA1 after incomplete cerebral ischemia in rats. ( Alici, HA; Cesur, M; Dogan, N; Erdem, AF; Erdogan, F; Kursad, H; Yuksek, MS, 2005) |
| "To study the protective effect of volatile anesthetics, isoflurane and sevoflurane, on ischemic neurons after cerebral ischemia-reperfusion in rats and its possible molecular mechanism." | 3.73 | Protective effect of isoflurane and sevoflurane on ischemic neurons and expression of Bcl-2 and ICE genes in rat brain. ( Li, DZ; Wan, H; Zhai, J; Zhang, H; Zhang, SD, 2006) |
| "In the present study, we tested the ability of sevoflurane to induce early and late preconditioning against ischemic neuronal injury using an in vivo model of global cerebral ischemia in the rat." | 3.73 | Sevoflurane-induced preconditioning protects against cerebral ischemic neuronal damage in rats. ( Akca, O; Kehl, F; Payne, RS; Roewer, N; Schurr, A, 2005) |
| "During incomplete cerebral ischemia, the neuroprotective anesthetics sevoflurane and propofol suppressed cerebral increases in norepinephrine and glutamate concentrations." | 3.72 | The effect of sevoflurane and propofol on cerebral neurotransmitter concentrations during cerebral ischemia in rats. ( Blobner, M; Engelhard, K; Hoffman, WE; Kochs, E; Matthes, B; Werner, C, 2003) |
| " In order to select a suitable volatile anaesthetic from the standpoint of cytoskeletal protein breakdown during cerebral ischemia, we compared the effect of isoflurane, halothane and sevoflurane on MAP 2 degradation during 20 min of forebrain ischemia in the rat." | 3.69 | [Effects of volatile anesthetics on microtubule-associated protein 2 degradation during forebrain ischemia in the rat]. ( Fujita, T; Kitani, Y; Morita, T; Saito, S; Sugaya, T; Uehara, K, 1994) |
| " We evaluated whether the effect of sevoflurane is similar to that of isoflurane or halothane on brain energy metabolism after cerebral ischemia followed by reperfusion using 31P-magnetic resonance spectroscopy." | 3.69 | The effects of sevoflurane on recovery of brain energy metabolism after cerebral ischemia in the rat: a comparison with isoflurane and halothane. ( Fujise, Y; Ikeda, K; Moriwaki, G; Nakajima, Y, 1997) |
| "We examined the effects of sevoflurane anesthesia with hypothermia on ischemic brain cellular respiration using Wistar strain rats." | 3.68 | [The effects of sevoflurane anesthesia with hypothermia on ischemic brain cellular respiration]. ( Kubota, N; Matsuo, R; Shibata, T; Takahashi, K; Yokoyama, H, 1993) |
| "Sevoflurane was discontinued and anesthesia continued with fentanyl/nitrous oxide for an additional 100 minutes." | 1.42 | Preischemic Administration of Sevoflurane Does not Exert Dose-dependent Effects on the Outcome of Severe Forebrain Ischemia in Rats. ( Kanazawa, K; Miura, Y; Nasu, I, 2015) |
| "Obesity is associated with increased infarct volumes and adverse outcomes following ischemic stroke." | 1.40 | Sevoflurane postconditioning against cerebral ischemic neuronal injury is abolished in diet-induced obesity: role of brain mitochondrial KATP channels. ( Chen, Y; Fang, X; Jiang, Y; Xu, J; Yang, Z; Zhang, Y, 2014) |
| "Focal cerebral ischemia was performed via 1h of middle cerebral artery occlusion (MCAO) followed by reperfusion." | 1.39 | Preconditioning with sevoflurane ameliorates spatial learning and memory deficit after focal cerebral ischemia-reperfusion in rats. ( Hu, X; Li, W; Li, Y; Liu, J; Zhang, Y, 2013) |
| "Sevoflurane pretreatment also suppressed the activation of astrocytes and microglias in ipsilateral cortex and corpus callosum." | 1.37 | Sevoflurane preconditioning protects blood-brain-barrier against brain ischemia. ( Chen, J; Chu, M; Gan, Y; Gao, H; Gao, Y; Li, P; Liang, W; Lu, S; Shi, H; Wang, H; Yu, Q, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 7 (11.29) | 18.2507 |
| 2000's | 17 (27.42) | 29.6817 |
| 2010's | 30 (48.39) | 24.3611 |
| 2020's | 8 (12.90) | 2.80 |
| Authors | Studies |
|---|---|
| Su, G | 1 |
| Qu, Y | 1 |
| Li, G | 1 |
| Deng, M | 1 |
| Yang, L | 1 |
| Chen, H | 2 |
| Guan, L | 1 |
| Xu, Y | 1 |
| Zhao, Z | 1 |
| Li, Y | 6 |
| Chi, F | 1 |
| Ma, L | 2 |
| Hou, Z | 1 |
| Wang, Q | 4 |
| Liang, Z | 1 |
| Lei, S | 1 |
| Wu, X | 1 |
| Yuan, T | 1 |
| Ma, K | 1 |
| Chi, K | 1 |
| Shang, S | 1 |
| Sun, F | 1 |
| Zhu, Y | 1 |
| Yu, J | 2 |
| Yu, L | 1 |
| Shao, W | 1 |
| Wang, Z | 1 |
| Yi, X | 1 |
| Wu, Q | 1 |
| Qin, M | 1 |
| Zhang, K | 1 |
| Zhen, L | 1 |
| Jia, W | 1 |
| Wei, H | 1 |
| Wang, S | 5 |
| Chen, J | 3 |
| Yoon, HK | 1 |
| Oh, H | 1 |
| Lee, HC | 1 |
| Cho, WS | 1 |
| Kim, JE | 1 |
| Park, JW | 1 |
| Choi, H | 1 |
| Park, HP | 2 |
| Zhong, H | 1 |
| Gu, C | 1 |
| Deng, Y | 1 |
| Shi, C | 1 |
| Gu, Y | 1 |
| Yang, N | 1 |
| Xu, M | 2 |
| Xu, T | 1 |
| Guo, X | 1 |
| Zhu, YM | 1 |
| Gao, X | 1 |
| Ni, Y | 1 |
| Li, W | 2 |
| Kent, TA | 1 |
| Qiao, SG | 1 |
| Wang, C | 1 |
| Xu, XX | 1 |
| Zhang, HL | 1 |
| Shi, CX | 1 |
| Ding, YB | 1 |
| Jin, FYJ | 1 |
| Li, T | 1 |
| Ma, JH | 1 |
| Qiao, LY | 1 |
| Pan, WZ | 1 |
| Li, KZ | 1 |
| Hu, X | 2 |
| Wang, J | 2 |
| Zhang, L | 3 |
| Zhang, Q | 1 |
| Duan, X | 1 |
| Zhang, Y | 6 |
| Wei, J | 1 |
| Li, P | 3 |
| Yang, Q | 4 |
| Seo, JH | 1 |
| Jeon, YT | 1 |
| Lim, YJ | 1 |
| Nam, K | 1 |
| Hwang, JW | 1 |
| Liu, J | 2 |
| Cabezón, L | 1 |
| Nogueira, C | 1 |
| Ramos, L | 1 |
| Vázquez-Fidalgo, A | 1 |
| Li, D | 2 |
| Huang, B | 1 |
| Li, L | 3 |
| Li, X | 4 |
| Tong, L | 1 |
| Cai, M | 1 |
| Huang, Y | 1 |
| Zhang, H | 2 |
| Su, B | 1 |
| Li, Z | 1 |
| Dong, H | 5 |
| Yang, Z | 1 |
| Chen, Y | 1 |
| Jiang, Y | 1 |
| Fang, X | 1 |
| Xu, J | 1 |
| Luo, P | 1 |
| Wang, F | 1 |
| Zhao, M | 1 |
| Xiong, L | 3 |
| Dong, P | 1 |
| Zhao, J | 1 |
| Dong, J | 1 |
| Zhang, X | 2 |
| Yang, B | 2 |
| Lei, W | 1 |
| Wang, JK | 2 |
| Wu, HF | 1 |
| Zhou, H | 1 |
| Liu, XZ | 1 |
| Miura, Y | 2 |
| Kanazawa, K | 1 |
| Nasu, I | 1 |
| Ye, Z | 2 |
| Xia, P | 2 |
| Cheng, ZG | 1 |
| Guo, Q | 2 |
| Tian, SY | 2 |
| Li, YW | 1 |
| Yu, JB | 1 |
| Li, J | 1 |
| Chen, YY | 1 |
| Wang, YX | 2 |
| Liang, Y | 2 |
| Zhang, XS | 1 |
| Wang, WS | 2 |
| Liu, HG | 2 |
| Liu, JJ | 1 |
| Pan, SY | 1 |
| Saiyin, H | 1 |
| Xie, J | 1 |
| Xue, L | 1 |
| Wang, W | 1 |
| Liang, W | 3 |
| Yu, Q | 3 |
| Sigaut, S | 1 |
| Jannier, V | 1 |
| Rouelle, D | 1 |
| Gressens, P | 1 |
| Mantz, J | 1 |
| Dahmani, S | 1 |
| Eberspächer, E | 4 |
| Eckel, B | 1 |
| Engelhard, K | 5 |
| Müller, K | 1 |
| Hoffman, WE | 2 |
| Blobner, M | 3 |
| Werner, C | 5 |
| Codaccioni, JL | 1 |
| Velly, LJ | 1 |
| Moubarik, C | 1 |
| Bruder, NJ | 1 |
| Pisano, PS | 1 |
| Guillet, BA | 1 |
| Lee, HM | 2 |
| Lee, DH | 1 |
| Choi, JH | 1 |
| Lee, SR | 1 |
| Kim, YW | 1 |
| Jee, DL | 1 |
| DO, HS | 1 |
| Park, SJ | 1 |
| Adamczyk, S | 1 |
| Robin, E | 1 |
| Simerabet, M | 1 |
| Kipnis, E | 1 |
| Tavernier, B | 1 |
| Vallet, B | 1 |
| Bordet, R | 1 |
| Lebuffe, G | 1 |
| Lin, HF | 1 |
| Zhu, ZR | 1 |
| Hu, ZY | 1 |
| Yu, LN | 1 |
| Zhang, FJ | 1 |
| Yang, MJ | 1 |
| Yan, M | 1 |
| Chen, G | 1 |
| Zhang, HJ | 1 |
| Wang, ZP | 2 |
| Hu, SQ | 1 |
| Jiang, S | 2 |
| Wang, H | 2 |
| Lu, S | 2 |
| Gao, H | 2 |
| Gan, Y | 2 |
| Gao, Y | 2 |
| Deng, J | 1 |
| Ye, R | 1 |
| Hu, S | 1 |
| Chu, M | 1 |
| Shi, H | 1 |
| Wang, N | 1 |
| Wang, E | 1 |
| Yuan, Y | 1 |
| Zuo, Z | 1 |
| Yan, W | 1 |
| Hou, L | 1 |
| Hua, Z | 1 |
| Meng, C | 1 |
| Ma, YP | 1 |
| Wang, L | 1 |
| Amagasa, S | 1 |
| Matthes, B | 1 |
| Kochs, E | 3 |
| Pape, M | 2 |
| Hutzler, P | 3 |
| Payne, RS | 1 |
| Akca, O | 1 |
| Roewer, N | 1 |
| Schurr, A | 1 |
| Kehl, F | 1 |
| Erdem, AF | 1 |
| Cesur, M | 1 |
| Alici, HA | 1 |
| Erdogan, F | 1 |
| Dogan, N | 1 |
| Kursad, H | 1 |
| Yuksek, MS | 1 |
| Zhang, ZH | 1 |
| Zeng, YM | 1 |
| Wang, SQ | 1 |
| Hollweck, R | 2 |
| Kellermann, K | 1 |
| Zintner, S | 1 |
| Zhang, SD | 1 |
| Zhai, J | 1 |
| Wan, H | 1 |
| Li, DZ | 1 |
| Lei, B | 1 |
| Popp, S | 1 |
| Meng, F | 1 |
| Cottrell, JE | 1 |
| Kass, IS | 1 |
| Fernández Sánchez, LJ | 1 |
| Pérez González, R | 1 |
| Guasch Arévalo, E | 1 |
| Martín Reyes, R | 1 |
| Gilsanz Rodríguez, F | 1 |
| Winkelheide, U | 1 |
| Kluge, J | 1 |
| Winkler, J | 1 |
| Sugaya, T | 1 |
| Kitani, Y | 1 |
| Saito, S | 1 |
| Uehara, K | 1 |
| Morita, T | 1 |
| Fujita, T | 1 |
| Kitaguchi, K | 1 |
| Ohsumi, H | 1 |
| Kuro, M | 1 |
| Nakajima, T | 1 |
| Hayashi, Y | 1 |
| Yokoyama, H | 1 |
| Shibata, T | 1 |
| Kubota, N | 1 |
| Matsuo, R | 1 |
| Takahashi, K | 1 |
| Drummond, JC | 1 |
| Warner, DS | 1 |
| McFarlane, C | 1 |
| Todd, MM | 1 |
| Ludwig, P | 1 |
| McAllister, AM | 1 |
| Nakajima, Y | 1 |
| Moriwaki, G | 1 |
| Ikeda, K | 1 |
| Fujise, Y | 1 |
| Grady, RE | 1 |
| Weglinski, MR | 1 |
| Sharbrough, FW | 1 |
| Perkins, WJ | 1 |
| Toner, CC | 1 |
| Connelly, K | 1 |
| Whelpton, R | 1 |
| Bains, S | 1 |
| Michael-Titus, AT | 1 |
| McLaughlin, DP | 1 |
| Stamford, JA | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Delirium Reduction by Volatile Anesthesia in Cardiac Surgery: Prospective, Randomized, Single-blinded Study[NCT03729011] | Phase 4 | 672 participants (Anticipated) | Interventional | 2019-01-09 | Recruiting | ||
| Effect of Sevoflurane-induced Postconditioning on the Incidence of Postoperative Cerebral Hyperperfusion Syndrome After Revascularization Surgery in Adult Patients With Moyamoya Disease[NCT02510586] | 152 participants (Anticipated) | Interventional | 2015-08-31 | Not yet recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for sevoflurane and Brain Ischemia
| Article | Year |
|---|---|
[Perioperative cerebral ischemia and the possibility of neuroprotection by inhalational anesthetics].
Topics: Anesthesia, General; Anesthetics, Inhalation; Animals; Brain; Brain Ischemia; Coronary Artery Bypass | 2003 |
3 trials available for sevoflurane and Brain Ischemia
| Article | Year |
|---|---|
Effect of Sevoflurane Postconditioning on the Incidence of Symptomatic Cerebral Hyperperfusion After Revascularization Surgery in Adult Patients with Moyamoya Disease.
Topics: Adult; Anesthetics, Inhalation; Brain Ischemia; Carbon Dioxide; Cerebral Revascularization; Female; | 2020 |
Effects of sevoflurane on cerebral circulation and metabolism in patients with ischemic cerebrovascular disease.
Topics: Adult; Anesthesia; Anesthetics; Blood Pressure; Brain; Brain Ischemia; Carbon Dioxide; Cerebrovascul | 1993 |
Correlation of regional cerebral blood flow with ischemic electroencephalographic changes during sevoflurane-nitrous oxide anesthesia for carotid endarterectomy.
Topics: Aged; Aged, 80 and over; Anesthetics, Inhalation; Brain Ischemia; Cerebrovascular Circulation; Dose- | 1998 |
58 other studies available for sevoflurane and Brain Ischemia
| Article | Year |
|---|---|
Sevoflurane protects against cerebral ischemia/reperfusion injury via microrna-30c-5p modulating homeodomain-interacting protein kinase 1.
Topics: Animals; Base Sequence; Brain Ischemia; Cell Line; Disease Models, Animal; Down-Regulation; Glucose; | 2021 |
Sevoflurane Offers Neuroprotection in a Cerebral Ischemia/Reperfusion Injury Rat Model Through the E2F1/EZH2/TIMP2 Regulatory Axis.
Topics: Animals; Apoptosis; Brain Ischemia; E2F1 Transcription Factor; Enhancer of Zeste Homolog 2 Protein; | 2022 |
Sevoflurane postconditioning ameliorates cerebral ischemia-reperfusion injury in rats via TLR4/MyD88/TRAF6 signaling pathway.
Topics: Animals; Brain Ischemia; Myeloid Differentiation Factor 88; Rats; Rats, Sprague-Dawley; Reperfusion | 2022 |
Sevoflurane Preconditioning Downregulates GRIA1 Expression to Attenuate Cerebral Ischemia-Reperfusion-Induced Neuronal Injury.
Topics: Animals; Apoptosis; Brain Ischemia; Cerebral Infarction; Glucose; Neurons; Neuroprotective Agents; O | 2023 |
Sevoflurane preconditioning improves neuroinflammation in cerebral ischemia/reperfusion induced rats through ROS-NLRP3 pathway.
Topics: Animals; Brain Ischemia; Caspase 1; Cerebral Infarction; Interleukin-18; Interleukin-6; Neuroinflamm | 2023 |
Synthesis of sevoflurane loaded reduced graphene oxide nanoparticles system for neuroprotective effects for preconditioning against focal cerebral ischaemia.
Topics: Animals; Brain; Brain Ischemia; Chemistry Techniques, Synthetic; Drug Carriers; Drug Liberation; Fas | 2019 |
[Regulatory T cells are involved in sevoflurane preconditioning-induced mouse brain protection against cerebral ischemia injury].
Topics: Animals; Brain; Brain Ischemia; Ischemic Preconditioning; Mice; Mice, Inbred C57BL; Reperfusion Inju | 2019 |
Sevoflurane Post-treatment Upregulated miR-203 Expression to Attenuate Cerebral Ischemia-Reperfusion-Induced Neuroinflammation by Targeting MyD88.
Topics: Animals; Brain Ischemia; Drug Delivery Systems; Gene Expression; Inflammation; Male; MicroRNAs; Myel | 2020 |
A study of optimal concentration range and time window of sevoflurane preconditioning for brain protection in MCAO rats.
Topics: Animals; Brain; Brain Ischemia; Dose-Response Relationship, Drug; Infarction, Middle Cerebral Artery | 2020 |
Sevoflurane postconditioning attenuates reactive astrogliosis and glial scar formation after ischemia-reperfusion brain injury.
Topics: Animals; Astrocytes; Brain Ischemia; Cells, Cultured; Disease Models, Animal; Glial Fibrillary Acidi | 2017 |
Effects of sevoflurane post-conditioning in cerebral ischemia-reperfusion injury via TLR4/NF-κB pathway in rats.
Topics: Animals; Brain Ischemia; Cytokines; Ischemic Postconditioning; Neuroprotective Agents; NF-kappa B; R | 2018 |
Postconditioning with sevoflurane ameliorates spatial learning and memory deficit via attenuating endoplasmic reticulum stress induced neuron apoptosis in a rat model of hemorrhage shock and resuscitation.
Topics: Animals; Apoptosis; Brain Ischemia; CA1 Region, Hippocampal; Disease Models, Animal; Endoplasmic Ret | 2018 |
Sevoflurane preconditioning induces tolerance to brain ischemia partially via inhibiting thioredoxin-1 nitration.
Topics: Administration, Inhalation; Animals; Brain Ischemia; Humans; Ischemic Preconditioning; Male; Nitrate | 2018 |
Combined treatment with celecoxib and sevoflurane after global cerebral ischaemia has no additive neuroprotective effects in rats.
Topics: Anesthetics, Inhalation; Animals; Brain Ischemia; Celecoxib; Cyclooxygenase 2 Inhibitors; Drug Syner | 2013 |
Preconditioning with sevoflurane ameliorates spatial learning and memory deficit after focal cerebral ischemia-reperfusion in rats.
Topics: Animals; Brain Ischemia; Cholinergic Neurons; Hippocampus; Male; Maze Learning; Memory Disorders; Me | 2013 |
[General anesthesia for an urgent cesarean in a pregnant woman with an acute cerebrovascular accident].
Topics: Adult; Anesthesia, Obstetrical; Anesthetics, General; Balanced Anesthesia; Brain Ischemia; Carotid A | 2014 |
Decreased brain K(ATP) channel contributes to exacerbating ischemic brain injury and the failure of neuroprotection by sevoflurane post-conditioning in diabetic rats.
Topics: Animals; Base Sequence; Brain; Brain Ischemia; Diabetes Mellitus, Experimental; DNA Primers; KATP Ch | 2013 |
Activation of K(2)P channel-TREK1 mediates the neuroprotection induced by sevoflurane preconditioning.
Topics: Animals; Brain; Brain Ischemia; Carbon Monoxide; Cell Differentiation; Cell Hypoxia; Cell Survival; | 2014 |
Sevoflurane postconditioning against cerebral ischemic neuronal injury is abolished in diet-induced obesity: role of brain mitochondrial KATP channels.
Topics: Animals; Body Weight; Brain; Brain Injuries; Brain Ischemia; Decanoic Acids; Diazoxide; Diet, High-F | 2014 |
Inhibition of N-myc downstream-regulated gene-2 is involved in an astrocyte-specific neuroprotection induced by sevoflurane preconditioning.
Topics: Active Transport, Cell Nucleus; Anesthetics, Inhalation; Animals; Apoptosis; Astrocytes; Brain Ische | 2014 |
Aging causes exacerbated ischemic brain injury and failure of sevoflurane post-conditioning: role of B-cell lymphoma-2.
Topics: Age Factors; Aging; Animals; Apoptosis; Brain; Brain Ischemia; Disease Models, Animal; Ischemic Post | 2014 |
Postconditioning with sevoflurane protects against focal cerebral ischemia and reperfusion injury involving mitochondrial ATP-dependent potassium channel and mitochondrial permeability transition pore.
Topics: Animals; Apoptosis; Brain Edema; Brain Ischemia; Disease Models, Animal; Infarction, Middle Cerebral | 2015 |
Preischemic Administration of Sevoflurane Does not Exert Dose-dependent Effects on the Outcome of Severe Forebrain Ischemia in Rats.
Topics: Anesthetics, Inhalation; Animals; Brain Ischemia; Disease Models, Animal; Dose-Response Relationship | 2015 |
Neuroprotection induced by sevoflurane-delayed post-conditioning is attributable to increased phosphorylation of mitochondrial GSK-3β through the PI3K/Akt survival pathway.
Topics: Anesthetics, Inhalation; Animals; Brain Ischemia; Glycogen Synthase Kinase 3; Glycogen Synthase Kina | 2015 |
Sevoflurane preconditioning improving cerebral focal ischemia-reperfusion damage in a rat model via PI3K/Akt signaling pathway.
Topics: Animals; Antioxidants; Apoptosis; Brain Ischemia; Gene Expression Regulation; Methyl Ethers; Oncogen | 2015 |
Protective effects of estrogen combined with sevoflurane in an experimental model of cerebral infarction and focal cerebral ischemia-reperfusion injury.
Topics: Animals; Brain Ischemia; Cerebral Infarction; Estrogens; Female; Infarction, Middle Cerebral Artery; | 2016 |
Sevoflurane preconditioning induced endogenous neurogenesis against ischemic brain injury by promoting microglial activation.
Topics: Animals; Axons; Brain Injuries; Brain Ischemia; Brain-Derived Neurotrophic Factor; Cell Differentiat | 2017 |
The preconditioning effect of sevoflurane on the oxygen glucose-deprived hippocampal slice: the role of tyrosine kinases and duration of ischemia.
Topics: Actins; Anesthetics, Inhalation; Animals; Blood Gas Analysis; Brain Ischemia; Caspase 3; Cell Death; | 2009 |
Effects of sevoflurane on cognitive deficit, motor function, and histopathology after cerebral ischemia in rats.
Topics: Anesthesia; Anesthetics; Anesthetics, Intravenous; Animals; Blood Gas Analysis; Brain; Brain Ischemi | 2009 |
Sevoflurane preconditioning against focal cerebral ischemia: inhibition of apoptosis in the face of transient improvement of neurological outcome.
Topics: Anesthetics, Inhalation; Animals; Apoptosis; Behavior, Animal; Brain Ischemia; DNA Fragmentation; In | 2009 |
Sevoflurane-induced post-conditioning has no beneficial effects on neuroprotection after incomplete cerebral ischemia in rats.
Topics: Anesthetics, Inhalation; Animals; Behavior, Animal; Brain Ischemia; Cerebral Cortex; Coloring Agents | 2010 |
Sevoflurane pre- and post-conditioning protect the brain via the mitochondrial K ATP channel.
Topics: Anesthetics, Inhalation; Animals; Brain Ischemia; Carbon Dioxide; Cerebral Infarction; Hemodynamics; | 2010 |
[Protective effects of sevoflurane preconditioning on cerebral ischemia-reperfusion injury in rats].
Topics: Animals; Apoptosis; Brain; Brain Ischemia; Disease Models, Animal; Ischemic Preconditioning; Male; M | 2009 |
Postconditioning with sevoflurane protects against focal cerebral ischemia and reperfusion injury via PI3K/Akt pathway.
Topics: Analysis of Variance; Animals; Apoptosis; Blotting, Western; Brain Ischemia; Immunohistochemistry; I | 2010 |
[Neuroprotection of sevoflurane against the ischemia injury in hippocampal slices of rat].
Topics: Anesthetics, Inhalation; Animals; Brain Ischemia; Excitatory Amino Acid Antagonists; Hippocampus; In | 2008 |
Sevoflurane preconditioning confers neuroprotection via anti-inflammatory effects.
Topics: Animals; Anti-Inflammatory Agents; Blotting, Western; Brain Ischemia; DNA Primers; Enzyme-Linked Imm | 2011 |
Sevoflurane preconditioning induces neuroprotection through reactive oxygen species-mediated up-regulation of antioxidant enzymes in rats.
Topics: Animals; Antioxidants; Brain Ischemia; Cerebrovascular Circulation; Dose-Response Relationship, Drug | 2011 |
Sevoflurane preconditioning protects blood-brain-barrier against brain ischemia.
Topics: Anesthetics, Inhalation; Animals; Blood-Brain Barrier; Blotting, Western; Brain Ischemia; Disease Mo | 2011 |
Sevoflurane postconditioning involves an up-regulation of HIF-1α and HO-1 expression via PI3K/Akt pathway in a rat model of focal cerebral ischemia.
Topics: Androstadienes; Animals; Brain Ischemia; Disease Models, Animal; Gene Expression Regulation; Heme Ox | 2012 |
A novel mechanism for sevoflurane preconditioning-induced neuroprotection.
Topics: Animals; Brain Ischemia; Ischemic Preconditioning; Male; Methyl Ethers; Receptor, Notch1; Sevofluran | 2012 |
Activation of canonical notch signaling pathway is involved in the ischemic tolerance induced by sevoflurane preconditioning in mice.
Topics: Animals; Brain Ischemia; Ischemic Preconditioning; Male; Methyl Ethers; Mice; Mice, Inbred C57BL; Mi | 2012 |
Effect of Sevoflurane postconditioning on gene expression in brain tissue of the middle cerebral artery occlusion rat model.
Topics: Animals; bcl-2-Associated X Protein; Brain; Brain Ischemia; Caspase 3; Catalase; Disease Models, Ani | 2012 |
The effect of sevoflurane and propofol on cerebral neurotransmitter concentrations during cerebral ischemia in rats.
Topics: Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Aspartic Acid; Blood Gas Analysis; Blood | 2003 |
Sevoflurane and propofol influence the expression of apoptosis-regulating proteins after cerebral ischaemia and reperfusion in rats.
Topics: Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Apoptosis; bcl-2-Associated X Protein; B | 2004 |
Sevoflurane-induced preconditioning protects against cerebral ischemic neuronal damage in rats.
Topics: Action Potentials; Anesthetics, Inhalation; Animals; Brain Ischemia; Cell Death; Disease Models, Ani | 2005 |
Effects of sevoflurane and desflurane in CA1 after incomplete cerebral ischemia in rats.
Topics: Analysis of Variance; Anesthetics, Inhalation; Animals; Biopsy, Needle; Brain Ischemia; Cerebrovascu | 2005 |
[Protective effect of sevoflurane preconditioning on oxygen-glucose deprivation injury in rat hippocampal slices: the role of mitochondrial K(ATP) channels].
Topics: Animals; Brain Ischemia; Cell Hypoxia; Female; Glucose; Hippocampus; In Vitro Techniques; Ischemic P | 2006 |
The long-term effect of sevoflurane on neuronal cell damage and expression of apoptotic factors after cerebral ischemia and reperfusion in rats.
Topics: Anesthetics, Inhalation; Animals; Apoptosis Regulatory Proteins; Blood Flow Velocity; Brain Ischemia | 2006 |
Protective effect of isoflurane and sevoflurane on ischemic neurons and expression of Bcl-2 and ICE genes in rat brain.
Topics: Anesthetics, Inhalation; Animals; Apoptosis; Brain Ischemia; Caspase 1; Flow Cytometry; Hippocampus; | 2006 |
Sevoflurane immediate preconditioning alters hypoxic membrane potential changes in rat hippocampal slices and improves recovery of CA1 pyramidal cells after hypoxia and global cerebral ischemia.
Topics: Animals; Brain Ischemia; Carbon Dioxide; Female; Glucose; Hippocampus; Hydrogen-Ion Concentration; H | 2007 |
[Perioperative treatment of a pregnant woman with recent cerebral infarction secondary to noncompaction cardiomyopathy].
Topics: Adrenergic beta-Antagonists; Androstanols; Anesthesia, General; Anesthesia, Inhalation; Anesthesia, | 2006 |
Sevoflurane affects neurogenesis after forebrain ischemia in rats.
Topics: Anesthetics, Inhalation; Animals; Brain Ischemia; Cell Proliferation; Dentate Gyrus; Disease Models, | 2007 |
[Effects of volatile anesthetics on microtubule-associated protein 2 degradation during forebrain ischemia in the rat].
Topics: Anesthetics, Inhalation; Animals; Brain Ischemia; Electroencephalography; Ethers; Halothane; Isoflur | 1994 |
[The effects of sevoflurane anesthesia with hypothermia on ischemic brain cellular respiration].
Topics: Anesthesia, Inhalation; Anesthetics; Animals; Brain Ischemia; Energy Metabolism; Ethers; Hypothermia | 1993 |
Brain protection during anesthesia. A reader's guide.
Topics: Anesthetics; Animals; Brain Injuries; Brain Ischemia; Ethers; Halothane; Humans; Hypothermia, Induce | 1993 |
Sevoflurane and halothane reduce focal ischemic brain damage in the rat. Possible influence on thermoregulation.
Topics: Anesthesia, Inhalation; Anesthetics; Animals; Body Temperature Regulation; Brain Ischemia; Ethers; H | 1993 |
The effects of sevoflurane on recovery of brain energy metabolism after cerebral ischemia in the rat: a comparison with isoflurane and halothane.
Topics: Adenosine Triphosphate; Anesthetics, Inhalation; Animals; Brain; Brain Ischemia; Energy Metabolism; | 1997 |
Effects of sevoflurane on dopamine, glutamate and aspartate release in an in vitro model of cerebral ischaemia.
Topics: Anesthetics, Inhalation; Animals; Aspartic Acid; Brain Ischemia; Corpus Striatum; Culture Techniques | 2001 |