Page last updated: 2024-11-04

sevoflurane and Blood Poisoning

sevoflurane has been researched along with Blood Poisoning in 16 studies

Sevoflurane: A non-explosive inhalation anesthetic used in the induction and maintenance of general anesthesia. It does not cause respiratory irritation and may also prevent PLATELET AGGREGATION.
sevoflurane : An ether compound having fluoromethyl and 1,1,1,3,3,3-hexafluoroisopropyl as the two alkyl groups.

Research Excerpts

ExcerptRelevanceReference
" The inhalative anesthetic sevoflurane has been shown to elicit protective effects in various inflammatory studies, but its role in peritonitis-induced sepsis remains elusive."8.02Sevoflurane Exerts Protective Effects in Murine Peritonitis-induced Sepsis via Hypoxia-inducible Factor 1α/Adenosine A2B Receptor Signaling. ( Fabian, F; Fecher, D; Fuhr, A; Gamper-Tsigaras, J; Konrad, FM; Ngamsri, KC; Reutershan, J; Steinke, M; Straub, A; Walles, H, 2021)
"Objective We compared the effects of sevoflurane and isoflurane on systemic inflammation, sepsis-associated encephalopathy, and memory impairment in a rat sepsis model of cecal ligation and puncture (CLP)-induced polymicrobial peritonitis."7.88Sevoflurane exerts brain-protective effects against sepsis-associated encephalopathy and memory impairment through caspase 3/9 and Bax/Bcl signaling pathway in a rat model of sepsis. ( Bagriacik, EU; Bedirli, A; Bedirli, N; Cavunt Bayraktar, A; Kavutçu, M; Ozkose, Z; Yilmaz, G, 2018)
"We have shown that systemic attenuation of inflammation by the volatile anaesthetic sevoflurane did not translate into attenuated neuro-inflammation in this LPS-induced inflammation model."7.85Sevoflurane attenuates systemic inflammation compared with propofol, but does not modulate neuro-inflammation: A laboratory rat study. ( Baumann, L; Beck-Schimmer, B; Booy, C; Eugster, P; Hasler, M; Restin, T; Schläpfer, M, 2017)
"To observe the effects of preconditioning with different concentrations of sevoflurane on cariomyocyte apoptosis and myocardial inflammation in rats with sepsis and explore the possible mechanism of sevoflurane for myocardial protection."7.80[Effects of sevoflurane preconditioning on cardiomyocyte apoptosis and myocardial inflammation in rats with sepsis]. ( Chen, W; Lai, J; Lin, P; Wang, H; Zhang, L, 2014)
"Sevoflurane is an anesthetic agent which also participates in protective mechanisms in sepsis, likely due to anti-inflammatory properties."7.79Effects of sevoflurane postconditioning on cell death, inflammation and TLR expression in human endothelial cells exposed to LPS. ( Álvarez, J; Baluja, A; Brea, D; Rodríguez, A; Rodríguez, J; Rodríguez-González, R; Taboada, M; Veiras Del Río, S, 2013)
"It is unknown how ketamine anesthesia immunologically affects the outcome of patients with postoperative septicemia."7.76The effect of ketamine anesthesia on the immune function of mice with postoperative septicemia. ( Habu, Y; Kazama, T; Kinoshita, M; Ogura, T; Seki, S; Shono, S; Takahashi, T, 2010)
" Sevoflurane combined with oxygen is widely applied in the clinic, and our previous study indicated that this regimen significantly reduced sepsis-induced inflammatory responses and that inhibition of NF-κB pathway activation may contribute to this protection effect."5.56A subanesthetic dose of sevoflurane combined with oxygen exerts bactericidal effects and prevents lung injury through the nitric oxide pathway during sepsis. ( Hou, L; Hu, Y; Luo, D; Luo, Z; Ma, H; Zhang, E; Zhao, X, 2020)
"Sevoflurane was used as the sole anaesthetic agent."5.31Influence of sepsis on sevoflurane minimum alveolar concentration in a porcine model. ( Allaouchiche, B; Chassard, D; Debon, R; Duflo, F; Tournadre, JP, 2001)
"Sevoflurane, a widely used inhalation anesthetic, has been shown to be cardioprotective in individuals with sepsis and myocardial dysfunction."4.12Molecular Mechanism of Sevoflurane Preconditioning Based on Whole-transcriptome Sequencing of Lipopolysaccharide-induced Cardiac Dysfunction in Mice. ( Li, H; Li, J; Li, S; Li, Y; Xie, J, 2022)
"The anesthetic sevoflurane (SEV) has been shown to protect against organ's injury during sepsis."4.12Sevoflurane ameliorates LPS-induced inflammatory injury of HK-2 cells through Sirtuin1/NF-κB pathway. ( Miaomiao, Y; Peipei, W; Ping, W; Shuo, W, 2022)
" The inhalative anesthetic sevoflurane has been shown to elicit protective effects in various inflammatory studies, but its role in peritonitis-induced sepsis remains elusive."4.02Sevoflurane Exerts Protective Effects in Murine Peritonitis-induced Sepsis via Hypoxia-inducible Factor 1α/Adenosine A2B Receptor Signaling. ( Fabian, F; Fecher, D; Fuhr, A; Gamper-Tsigaras, J; Konrad, FM; Ngamsri, KC; Reutershan, J; Steinke, M; Straub, A; Walles, H, 2021)
"Objective We compared the effects of sevoflurane and isoflurane on systemic inflammation, sepsis-associated encephalopathy, and memory impairment in a rat sepsis model of cecal ligation and puncture (CLP)-induced polymicrobial peritonitis."3.88Sevoflurane exerts brain-protective effects against sepsis-associated encephalopathy and memory impairment through caspase 3/9 and Bax/Bcl signaling pathway in a rat model of sepsis. ( Bagriacik, EU; Bedirli, A; Bedirli, N; Cavunt Bayraktar, A; Kavutçu, M; Ozkose, Z; Yilmaz, G, 2018)
"We have shown that systemic attenuation of inflammation by the volatile anaesthetic sevoflurane did not translate into attenuated neuro-inflammation in this LPS-induced inflammation model."3.85Sevoflurane attenuates systemic inflammation compared with propofol, but does not modulate neuro-inflammation: A laboratory rat study. ( Baumann, L; Beck-Schimmer, B; Booy, C; Eugster, P; Hasler, M; Restin, T; Schläpfer, M, 2017)
"To observe the effects of preconditioning with different concentrations of sevoflurane on cariomyocyte apoptosis and myocardial inflammation in rats with sepsis and explore the possible mechanism of sevoflurane for myocardial protection."3.80[Effects of sevoflurane preconditioning on cardiomyocyte apoptosis and myocardial inflammation in rats with sepsis]. ( Chen, W; Lai, J; Lin, P; Wang, H; Zhang, L, 2014)
"Sevoflurane is an anesthetic agent which also participates in protective mechanisms in sepsis, likely due to anti-inflammatory properties."3.79Effects of sevoflurane postconditioning on cell death, inflammation and TLR expression in human endothelial cells exposed to LPS. ( Álvarez, J; Baluja, A; Brea, D; Rodríguez, A; Rodríguez, J; Rodríguez-González, R; Taboada, M; Veiras Del Río, S, 2013)
"Mice (N = 12 per treatment group) were exposed to anesthetic concentrations of desflurane, isoflurane, and sevoflurane either during induction of sepsis or when the mice showed pronounced symptoms of inflammation."3.79Volatile anesthetics improve survival after cecal ligation and puncture. ( Beck-Schimmer, B; Castellon, M; Hasler, M; Herrmann, IK; Hu, G; Minshall, RD; Schwartz, DE; Urner, M, 2013)
"This study aimed to evaluate the differential protective effects of isoflurane or sevoflurane on lung inflammation in a rat model of cecal ligation and puncture (CLP) induced sepsis."3.78Volatile anesthetic preconditioning attenuated sepsis induced lung inflammation. ( Akkaya, T; Alper, M; Bedirli, A; Bedirli, N; Demirtas, CY; Pasaoglu, H; Salman, B, 2012)
"It is unknown how ketamine anesthesia immunologically affects the outcome of patients with postoperative septicemia."3.76The effect of ketamine anesthesia on the immune function of mice with postoperative septicemia. ( Habu, Y; Kazama, T; Kinoshita, M; Ogura, T; Seki, S; Shono, S; Takahashi, T, 2010)
"The current study demonstrates that pre-treatment with sevoflurane minimizes myocardial dysfunction and the incidence of reperfusion arrhythmia after brief ischaemic insults in septic hearts."3.71Sevoflurane preconditions stunned myocardium in septic but not healthy isolated rat hearts. ( Ai, K; Innami, Y; Kosugi, S; Kotake, Y; Morisaki, H; Morita, Y; Satoh, T; Serita, R; Takeda, J, 2002)
" Sevoflurane combined with oxygen is widely applied in the clinic, and our previous study indicated that this regimen significantly reduced sepsis-induced inflammatory responses and that inhibition of NF-κB pathway activation may contribute to this protection effect."1.56A subanesthetic dose of sevoflurane combined with oxygen exerts bactericidal effects and prevents lung injury through the nitric oxide pathway during sepsis. ( Hou, L; Hu, Y; Luo, D; Luo, Z; Ma, H; Zhang, E; Zhao, X, 2020)
"Myocardial dysfunction accompanied by severe sepsis could significantly increase the mortality rate of septic patients."1.51Sevoflurane Preconditioning Prevents Septic Myocardial Dysfunction in Lipopolysaccharide-Challenged Mice. ( Chen, Y; Li, H; Li, J; Li, Y; Liu, P; Qi, R; Wang, Y, 2019)
"Sevoflurane was used as the sole anaesthetic agent."1.31Influence of sepsis on sevoflurane minimum alveolar concentration in a porcine model. ( Allaouchiche, B; Chassard, D; Debon, R; Duflo, F; Tournadre, JP, 2001)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (12.50)29.6817
2010's9 (56.25)24.3611
2020's5 (31.25)2.80

Authors

AuthorsStudies
Xie, J1
Li, H2
Li, S1
Li, J2
Li, Y2
Peipei, W1
Ping, W1
Miaomiao, Y1
Shuo, W1
Liu, P1
Wang, Y1
Chen, Y1
Qi, R1
Zhang, E1
Zhao, X1
Ma, H1
Luo, D1
Hu, Y1
Hou, L1
Luo, Z1
Chen, H1
Peng, Y1
Wang, L1
Wang, X1
Ngamsri, KC1
Fabian, F1
Fuhr, A1
Gamper-Tsigaras, J1
Straub, A1
Fecher, D1
Steinke, M1
Walles, H1
Reutershan, J1
Konrad, FM1
Beck-Schimmer, B2
Baumann, L1
Restin, T1
Eugster, P1
Hasler, M2
Booy, C1
Schläpfer, M1
Bedirli, N2
Bagriacik, EU1
Yilmaz, G1
Ozkose, Z1
Kavutçu, M1
Cavunt Bayraktar, A1
Bedirli, A2
Rodríguez-González, R1
Baluja, A1
Veiras Del Río, S1
Rodríguez, A1
Rodríguez, J1
Taboada, M1
Brea, D1
Álvarez, J1
Herrmann, IK1
Castellon, M1
Schwartz, DE1
Urner, M1
Hu, G1
Minshall, RD1
Lai, J1
Zhang, L1
Wang, H1
Lin, P1
Chen, W1
Chen, P1
Sinha, A1
Takahashi, T1
Kinoshita, M1
Shono, S1
Habu, Y1
Ogura, T1
Seki, S1
Kazama, T1
Demirtas, CY1
Akkaya, T1
Salman, B1
Alper, M1
Pasaoglu, H1
Serita, R1
Morisaki, H1
Ai, K1
Morita, Y1
Innami, Y1
Satoh, T1
Kosugi, S1
Kotake, Y1
Takeda, J1
Allaouchiche, B1
Duflo, F1
Tournadre, JP1
Debon, R1
Chassard, D1

Other Studies

16 other studies available for sevoflurane and Blood Poisoning

ArticleYear
Molecular Mechanism of Sevoflurane Preconditioning Based on Whole-transcriptome Sequencing of Lipopolysaccharide-induced Cardiac Dysfunction in Mice.
    Journal of cardiovascular pharmacology, 2022, 06-01, Volume: 79, Issue:6

    Topics: Animals; Heart Diseases; Lipopolysaccharides; Mice; MicroRNAs; Mitogen-Activated Protein Kinases; Ne

2022
Sevoflurane ameliorates LPS-induced inflammatory injury of HK-2 cells through Sirtuin1/NF-κB pathway.
    Allergologia et immunopathologia, 2022, Volume: 50, Issue:4

    Topics: Acute Kidney Injury; Epithelial Cells; Humans; Inflammation; Lipopolysaccharides; NF-kappa B; Sepsis

2022
Sevoflurane Preconditioning Prevents Septic Myocardial Dysfunction in Lipopolysaccharide-Challenged Mice.
    Journal of cardiovascular pharmacology, 2019, Volume: 74, Issue:5

    Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Cytokines; Disease Models, Animal; Drug Administrat

2019
A subanesthetic dose of sevoflurane combined with oxygen exerts bactericidal effects and prevents lung injury through the nitric oxide pathway during sepsis.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2020, Volume: 127

    Topics: Acute Lung Injury; Anesthetics, Inhalation; Animals; Anti-Bacterial Agents; Bronchoalveolar Lavage F

2020
Sevoflurane attenuates cognitive dysfunction and NLRP3-dependent caspase-1/11-GSDMD pathway-mediated pyroptosis in the hippocampus
    Archives of physiology and biochemistry, 2022, Volume: 128, Issue:5

    Topics: Adaptor Proteins, Vesicular Transport; Animals; Caspase 1; Cognitive Dysfunction; Cytokines; Hippoca

2022
Sevoflurane Exerts Protective Effects in Murine Peritonitis-induced Sepsis via Hypoxia-inducible Factor 1α/Adenosine A2B Receptor Signaling.
    Anesthesiology, 2021, 07-01, Volume: 135, Issue:1

    Topics: Anesthetics, Inhalation; Animals; Disease Models, Animal; Hypoxia-Inducible Factor 1; Male; Mice; Mi

2021
Sevoflurane attenuates systemic inflammation compared with propofol, but does not modulate neuro-inflammation: A laboratory rat study.
    European journal of anaesthesiology, 2017, Volume: 34, Issue:11

    Topics: Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Inflammation; Inflammation Mediators; Li

2017
Sevoflurane exerts brain-protective effects against sepsis-associated encephalopathy and memory impairment through caspase 3/9 and Bax/Bcl signaling pathway in a rat model of sepsis.
    The Journal of international medical research, 2018, Volume: 46, Issue:7

    Topics: Anesthetics, Inhalation; Animals; Anti-Bacterial Agents; Apoptosis; bcl-2-Associated X Protein; Brai

2018
Effects of sevoflurane postconditioning on cell death, inflammation and TLR expression in human endothelial cells exposed to LPS.
    Journal of translational medicine, 2013, Apr-03, Volume: 11

    Topics: Cell Death; Cell Survival; Culture Media; Escherichia coli; Gene Expression Regulation; Human Umbili

2013
Volatile anesthetics improve survival after cecal ligation and puncture.
    Anesthesiology, 2013, Volume: 119, Issue:4

    Topics: Anesthetics, Inhalation; Animals; Cecum; Desflurane; Disease Models, Animal; Inflammation; Isofluran

2013
[Effects of sevoflurane preconditioning on cardiomyocyte apoptosis and myocardial inflammation in rats with sepsis].
    Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2014, Volume: 34, Issue:11

    Topics: Animals; Apoptosis; Male; Methyl Ethers; Myocarditis; Myocardium; Myocytes, Cardiac; Rats; Rats, Spr

2014
Anaesthetic management of a parturient with factor VII deficiency and sepsis.
    International journal of obstetric anesthesia, 2015, Volume: 24, Issue:4

    Topics: Adult; Anesthesia, General; Anesthetics, Inhalation; Cesarean Section; Factor VII Deficiency; Female

2015
The effect of ketamine anesthesia on the immune function of mice with postoperative septicemia.
    Anesthesia and analgesia, 2010, Volume: 111, Issue:4

    Topics: Anesthesia; Animals; Cytokines; Escherichia coli; Escherichia coli Infections; Ketamine; Laparotomy;

2010
Volatile anesthetic preconditioning attenuated sepsis induced lung inflammation.
    The Journal of surgical research, 2012, Volume: 178, Issue:1

    Topics: Anesthetics, Inhalation; Animals; Cecum; Disease Models, Animal; Intercellular Adhesion Molecule-1;

2012
Sevoflurane preconditions stunned myocardium in septic but not healthy isolated rat hearts.
    British journal of anaesthesia, 2002, Volume: 89, Issue:6

    Topics: Anesthetics, Inhalation; Animals; Arrhythmias, Cardiac; Cardiac Output; Heart; Ischemic Precondition

2002
Influence of sepsis on sevoflurane minimum alveolar concentration in a porcine model.
    British journal of anaesthesia, 2001, Volume: 86, Issue:6

    Topics: Analgesics; Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Ketamine; Methyl Ethers; Mod

2001