sevoflurane has been researched along with Benign Neoplasms in 26 studies
Sevoflurane: A non-explosive inhalation anesthetic used in the induction and maintenance of general anesthesia. It does not cause respiratory irritation and may also prevent PLATELET AGGREGATION.
sevoflurane : An ether compound having fluoromethyl and 1,1,1,3,3,3-hexafluoroisopropyl as the two alkyl groups.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Based on animal data only, some clinicians have adopted propofol-based anesthesia for cancer surgery with the aim of increased survival." | 9.30 | Rationale and Design of the CAN Study: an RCT of Survival after Propofol- or Sevoflurane-based Anesthesia for Cancer Surgery. ( Bergkvist, L; Berglund, A; Enlund, A; Enlund, M, 2019) |
| "Sevoflurane is a new inhaled anesthetic, which has better physical properties than the existing inhalational anesthetics, rapid induction, less tissue uptake, and faster recovery." | 5.91 | Fgf2 and Ptpn11 play a role in cerebral injury caused by sevoflurane anesthesia. ( Xu, L; Zhang, L, 2023) |
| "Based on animal data only, some clinicians have adopted propofol-based anesthesia for cancer surgery with the aim of increased survival." | 5.30 | Rationale and Design of the CAN Study: an RCT of Survival after Propofol- or Sevoflurane-based Anesthesia for Cancer Surgery. ( Bergkvist, L; Berglund, A; Enlund, A; Enlund, M, 2019) |
| "In patients with previous or existing malignant disease, neither duration of anesthesia nor increased cumulative time with profound sevoflurane anesthesia was associated with an increased risk for new cancer or death within 5 years after surgery." | 3.80 | Cumulated time with low bispectral index values is not related to the risk of new cancer or death within 5 years after surgery in patients with previous or prevailing malignancy. ( Brudin, L; Lindholm, ML; Sandin, RH, 2014) |
| "anaesthesia might reduce cancer recurrence compared with volatile anaesthesia, but clinical information is observational only." | 3.30 | Long-term survival in older patients given propofol or sevoflurane anaesthesia for major cancer surgery: follow-up of a multicentre randomised trial. ( Ai, YQ; Cao, SJ; Guo, YQ; Jia, Z; Li, HJ; Li, XY; Liu, ZH; Ma, D; Ma, JH; Ouyang, W; Pan, LH; Sessler, DI; Sun, XD; Wang, DX; Wang, MR; Ye, QS; Yin, N; Yu, JB; Zhang, FX; Zhang, Y; Zhang, YX; Zhao, BJ; Zhao, W, 2023) |
| "Elderly patients who have solid organ cancer often receive surgery." | 2.84 | Impact of inhalational versus intravenous anaesthesia on early delirium and long-term survival in elderly patients after cancer surgery: study protocol of a multicentre, open-label, and randomised controlled trial. ( Ai, YQ; Guo, YQ; Jia, HQ; Jia, Z; Li, HJ; Liu, ZH; Ma, D; Ouyang, W; Pan, LH; Sun, XD; Tan, HY; Wang, DX; Yang, XD; Ye, QS; Yin, N; Yu, JB; Zhang, FX; Zhang, QG; Zhang, Y; Zhao, BJ, 2017) |
| "Propofol use is encouraged in cancers that appear to have a better prognosis after its use during surgery." | 2.66 | Effects of propofol on the development of cancer in humans. ( Jiang, W; Pan, S; Xu, Y; Xue, F; Zhu, X, 2020) |
| "Anaesthetics may modify colorectal cancer cell biology which potentially affects long-term survival." | 1.91 | The differential cancer growth associated with anaesthetics in a cancer xenograft model of mice: mechanisms and implications of postoperative cancer recurrence. ( Buggy, D; Hu, C; Ishikawa, M; Iwasaki, M; Ma, D; Saito, J; Sakamoto, A; Sherwin, A; Wu, L; Zhao, H, 2023) |
| "Moreover, propofol protected cancer cells from RSL3-induced ferroptosis in vitro, as evidenced by decreases in intracellular levels of reactive oxygen species (ROS), lipid peroxide, and ferroptosis markers." | 1.91 | Anesthetic propofol inhibits ferroptosis and aggravates distant cancer metastasis via Nrf2 upregulation. ( Hou, Q; Li, S; Ma, Y; Sun, L; Wang, H; Yuan, J; Zhang, B; Zhang, X; Zhao, X; Zheng, H, 2023) |
| "Patients aged 65-90 yr undergoing major cancer surgery were randomised to either propofol-based anaesthesia or to sevoflurane-based anaesthesia." | 1.91 | Delirium in older patients given propofol or sevoflurane anaesthesia for major cancer surgery: a multicentre randomised trial. ( Ai, YQ; Cao, SJ; Guo, YQ; Jia, Z; Li, HJ; Li, XY; Liu, ZH; Ma, D; Ma, JH; Ouyang, W; Pan, LH; Sessler, DI; Sun, XD; Wang, DX; Wang, MR; Ye, QS; Yin, N; Yu, JB; Zhang, FX; Zhang, Y; Zhang, YX; Zhao, BJ; Zhao, W, 2023) |
| "Sevoflurane is a new inhaled anesthetic, which has better physical properties than the existing inhalational anesthetics, rapid induction, less tissue uptake, and faster recovery." | 1.91 | Fgf2 and Ptpn11 play a role in cerebral injury caused by sevoflurane anesthesia. ( Xu, L; Zhang, L, 2023) |
| "Sevoflurane anesthesia was identified as an independent risk factor for recurrence-free survival." | 1.62 | Long-term survival differences between sevoflurane and propofol use in general anesthesia for gynecologic cancer surgery. ( Amano, E; Hirao, M; Matsumoto, H; Miyo, M; Shibuya, H; Takeyama, E; Tatsumi, K, 2021) |
| "We investigated the incidence of cancer within 5 years after surgery in relation to duration of anesthesia (T(ANESTH)) and also by time with bispectral index (BIS) under 45 (T(BIS<45)) serving as a proxy for more profound anesthesia exposure." | 1.37 | Malignant disease within 5 years after surgery in relation to duration of sevoflurane anesthesia and time with bispectral index under 45. ( Eriksson, LI; Granath, F; Lindholm, ML; Sandin, R, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (3.85) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (3.85) | 29.6817 |
| 2010's | 10 (38.46) | 24.3611 |
| 2020's | 14 (53.85) | 2.80 |
| Authors | Studies |
|---|---|
| Iwasaki, M | 1 |
| Zhao, H | 1 |
| Hu, C | 1 |
| Saito, J | 1 |
| Wu, L | 1 |
| Sherwin, A | 1 |
| Ishikawa, M | 1 |
| Sakamoto, A | 1 |
| Buggy, D | 1 |
| Ma, D | 6 |
| Allison, DW | 1 |
| Hayworth, MK | 1 |
| Nader, R | 1 |
| Ballman, M | 1 |
| Sun, D | 1 |
| Ninan, R | 1 |
| Southern, E | 1 |
| Zhang, B | 1 |
| Hou, Q | 1 |
| Zhang, X | 1 |
| Ma, Y | 1 |
| Yuan, J | 1 |
| Li, S | 1 |
| Zhao, X | 1 |
| Sun, L | 1 |
| Wang, H | 1 |
| Zheng, H | 1 |
| Mincer, JS | 1 |
| Buggy, DJ | 1 |
| Cao, SJ | 3 |
| Zhang, Y | 4 |
| Zhang, YX | 3 |
| Zhao, W | 2 |
| Pan, LH | 3 |
| Sun, XD | 3 |
| Jia, Z | 3 |
| Ouyang, W | 3 |
| Ye, QS | 3 |
| Zhang, FX | 3 |
| Guo, YQ | 3 |
| Ai, YQ | 3 |
| Zhao, BJ | 3 |
| Yu, JB | 3 |
| Liu, ZH | 3 |
| Yin, N | 3 |
| Li, XY | 2 |
| Ma, JH | 2 |
| Li, HJ | 4 |
| Wang, MR | 2 |
| Sessler, DI | 2 |
| Wang, DX | 4 |
| Park, JY | 1 |
| Yu, J | 1 |
| Kim, CS | 1 |
| Baek, JW | 1 |
| Jo, Y | 1 |
| Kim, YK | 1 |
| Coeckelenbergh, S | 1 |
| Soucy-Proulx, M | 1 |
| Radtke, FM | 1 |
| Sun, Z | 1 |
| Sui, J | 1 |
| Zhang, L | 1 |
| Xu, L | 1 |
| Guo, L | 1 |
| Lin, F | 1 |
| Dai, H | 1 |
| Du, X | 1 |
| Yu, M | 1 |
| Zhang, J | 1 |
| Huang, H | 1 |
| Ge, W | 1 |
| Tao, G | 1 |
| Pan, L | 1 |
| Qureshi, MZ | 1 |
| Attar, R | 1 |
| Javed, A | 1 |
| Sabitaliyevich, UY | 1 |
| Adylova, A | 1 |
| Konysbayevna, KK | 1 |
| Buha, A | 1 |
| Sohail, MI | 1 |
| Aras, A | 1 |
| Xu, Y | 1 |
| Pan, S | 1 |
| Jiang, W | 1 |
| Xue, F | 1 |
| Zhu, X | 1 |
| Bai, Y | 1 |
| Li, CS | 1 |
| Lu, XH | 1 |
| Zhou, Y | 1 |
| Miao, CH | 1 |
| Takeyama, E | 1 |
| Miyo, M | 1 |
| Matsumoto, H | 1 |
| Tatsumi, K | 1 |
| Amano, E | 1 |
| Hirao, M | 1 |
| Shibuya, H | 1 |
| Soltanizadeh, S | 1 |
| Degett, TH | 1 |
| Gögenur, I | 1 |
| Jia, HQ | 1 |
| Yang, XD | 1 |
| Zhang, QG | 1 |
| Tan, HY | 1 |
| Shan, GJ | 1 |
| Zhu, SN | 1 |
| Enlund, M | 2 |
| Enlund, A | 2 |
| Berglund, A | 2 |
| Bergkvist, L | 2 |
| Lindholm, ML | 2 |
| Brudin, L | 1 |
| Sandin, RH | 1 |
| Andreasson, K | 1 |
| Cicek, C | 1 |
| Evans, DR | 1 |
| Fowler-Williams, C | 1 |
| Granath, F | 1 |
| Eriksson, LI | 1 |
| Sandin, R | 1 |
| Leslie, K | 1 |
| Short, TG | 1 |
| HELD, F | 1 |
| Glaisyer, HR | 1 |
| Sury, MRJ | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Impact of Inhalational Versus Intravenous Anesthesia Maintenance Methods on Long-term Survival in Elderly Patients After Cancer Surgery: a Randomized Controlled Trial[NCT02660411] | 1,228 participants (Actual) | Interventional | 2015-04-01 | Completed | |||
| Impact of Inhalational Versus Intravenous Anesthesia Maintenance Methods on Incidence of Postoperative Delirium in Elderly Patients After Cancer Surgery: An Open-label, Randomized Controlled Trial[NCT02662257] | 1,228 participants (Actual) | Interventional | 2015-04-01 | Completed | |||
| Comparison of Propofol and Sevoflurane Anesthesia on the Quality of Recovery After Ambulatory Surgery for Anal Fistula in Obese Patients: A Prospective, Randomized, Single-blinded, Controlled Clinical Trial[NCT05529875] | 0 participants (Actual) | Interventional | 2022-10-31 | Withdrawn (stopped due to In the early stage of the research, this research was limited by the application permission of research drugs and instruments, and the research will have to be interrupted, which is extremely regrettable.) | |||
| A Randomized, Open-label Study to Compare Propofol Anesthesia With Sevoflurane Anesthesia in Terms of Overall Survival in Patients With Surgical Intervention for Either Breast-, Colon- or Rectal Cancer[NCT01975064] | Phase 4 | 5,774 participants (Actual) | Interventional | 2013-11-30 | Completed | ||
| Impact of Inhalational Versus Intravenous Anesthesia Maintenance Methods on 5-year Survival in Elderly Patients After Cancer Surgery: a Randomized Controlled Trial[NCT05343260] | 1,228 participants (Actual) | Interventional | 2015-04-01 | Active, not recruiting | |||
| Cancer Mortality Affected by the Choice of Anesthetic Drugs?[NCT01418326] | 3,284 participants (Actual) | Observational | 2010-11-30 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 reviews available for sevoflurane and Benign Neoplasms
| Article | Year |
|---|---|
Focusing on the brighter side of Sevoflurane: Realizing true potential of an anesthetic agent as a regulator of cell signaling pathways and microRNAs in different cancers.
Topics: Anesthetics; Apoptosis; Humans; MicroRNAs; Neoplasms; PTEN Phosphohydrolase; rho-Associated Kinases; | 2019 |
Effects of propofol on the development of cancer in humans.
Topics: Anesthetics, Intravenous; Animals; Gene Expression Regulation, Neoplastic; Humans; Neoplasms; Propof | 2020 |
Outcomes of cancer surgery after inhalational and intravenous anesthesia: A systematic review.
Topics: Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthetics, Inhalation; Anesthetics, Intravenous; | 2017 |
Is Volatile Anesthesia During Cancer Surgery Likely to Increase the Metastatic Risk?
Topics: Anesthesia; Anesthetics, Inhalation; Humans; Isoflurane; Methyl Ethers; Neoplasm Metastasis; Neoplas | 2016 |
10 trials available for sevoflurane and Benign Neoplasms
| Article | Year |
|---|---|
Long-term survival in older patients given propofol or sevoflurane anaesthesia for major cancer surgery: follow-up of a multicentre randomised trial.
Topics: Aged; Anesthesia, Inhalation; Anesthetics, Intravenous; Cancer Survivors; Female; Follow-Up Studies; | 2023 |
Comparison of the effects of 5 and 10 L/minute fresh gas flow on emergence from sevoflurane anesthesia: A randomized clinical trial.
Topics: Anesthesia, Inhalation; Anesthesiology; Anesthetics, Inhalation; Humans; Methyl Ethers; Neoplasms; S | 2023 |
Delirium in older patients given propofol or sevoflurane anaesthesia for major cancer surgery: a multicentre randomised trial. Comment on Br J Anaesth 2023; 131: 253-65.
Topics: Aged; Anesthesia; Anesthetics, Inhalation; Anesthetics, Intravenous; Delirium; Humans; Methyl Ethers | 2023 |
Delirium in older patients given propofol or sevoflurane anaesthesia for major cancer surgery: a multicentre randomised trial. Comment on Br J Anaesth 2023; 131: 253-65.
Topics: Aged; Anesthesia; Anesthetics, Inhalation; Anesthetics, Intravenous; Delirium; Humans; Methyl Ethers | 2023 |
Impact of Sevoflurane Versus Propofol Anesthesia on Post-Operative Cognitive Dysfunction in Elderly Cancer Patients: A Double-Blinded Randomized Controlled Trial.
Topics: Aged; Anesthesia, Intravenous; Anesthetics, Intravenous; Double-Blind Method; Female; Follow-Up Stud | 2020 |
[Effects of desflurane and sevoflurane anesthesia on postoperative recovery after long-term tumor surgery].
Topics: Anesthesia Recovery Period; Anesthetics, Inhalation; Desflurane; Humans; Isoflurane; Methyl Ethers; | 2020 |
Impact of inhalational versus intravenous anaesthesia on early delirium and long-term survival in elderly patients after cancer surgery: study protocol of a multicentre, open-label, and randomised controlled trial.
Topics: Aged; Aged, 80 and over; Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intravenous; Chi | 2017 |
Impact of inhalational versus intravenous anaesthesia on early delirium and long-term survival in elderly patients after cancer surgery: study protocol of a multicentre, open-label, and randomised controlled trial.
Topics: Aged; Aged, 80 and over; Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intravenous; Chi | 2017 |
Impact of inhalational versus intravenous anaesthesia on early delirium and long-term survival in elderly patients after cancer surgery: study protocol of a multicentre, open-label, and randomised controlled trial.
Topics: Aged; Aged, 80 and over; Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intravenous; Chi | 2017 |
Impact of inhalational versus intravenous anaesthesia on early delirium and long-term survival in elderly patients after cancer surgery: study protocol of a multicentre, open-label, and randomised controlled trial.
Topics: Aged; Aged, 80 and over; Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intravenous; Chi | 2017 |
Propofol compared with sevoflurane general anaesthesia is associated with decreased delayed neurocognitive recovery in older adults.
Topics: Aged; Aged, 80 and over; Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intravenous; Cog | 2018 |
Rationale and Design of the CAN Study: an RCT of Survival after Propofol- or Sevoflurane-based Anesthesia for Cancer Surgery.
Topics: Anesthesia; Anesthetics, Inhalation; Anesthetics, Intravenous; Humans; Multicenter Studies as Topic; | 2019 |
Recovery after anesthesia for short pediatric oncology procedures: propofol and remifentanil compared with propofol, nitrous oxide, and sevoflurane.
Topics: Anesthesia Recovery Period; Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthetics, Inhalation | 2005 |
12 other studies available for sevoflurane and Benign Neoplasms
| Article | Year |
|---|---|
The differential cancer growth associated with anaesthetics in a cancer xenograft model of mice: mechanisms and implications of postoperative cancer recurrence.
Topics: Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Caco-2 Cells; Heterografts; Humans; Lipo | 2023 |
Intraoperative transabdominal MEPs: four case reports.
Topics: Evoked Potentials, Motor; Humans; Intraoperative Neurophysiological Monitoring; Muscle, Skeletal; Ne | 2023 |
Anesthetic propofol inhibits ferroptosis and aggravates distant cancer metastasis via Nrf2 upregulation.
Topics: Anesthetics; Animals; Mice; Neoplasms; NF-E2-Related Factor 2; Propofol; Sevoflurane; Up-Regulation | 2023 |
Anaesthesia, analgesia, and cancer outcomes: time to think like oncologists?
Topics: Aged; Analgesia; Anesthesia, General; Anesthesiology; Anesthetics; Follow-Up Studies; Humans; Neopla | 2023 |
Delirium in older patients given propofol or sevoflurane anaesthesia for major cancer surgery: a multicentre randomised trial.
Topics: Aged; Anesthesia, General; Anesthetics, Inhalation; Emergence Delirium; Female; Follow-Up Studies; H | 2023 |
Fgf2 and Ptpn11 play a role in cerebral injury caused by sevoflurane anesthesia.
Topics: Anesthesia; Brain Injuries; Computational Biology; Fibroblast Growth Factor 2; Gene Expression Profi | 2023 |
Long-term survival differences between sevoflurane and propofol use in general anesthesia for gynecologic cancer surgery.
Topics: Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intravenous; Female; Humans; Methyl Ether | 2021 |
Cumulated time with low bispectral index values is not related to the risk of new cancer or death within 5 years after surgery in patients with previous or prevailing malignancy.
Topics: Adult; Aged; Anesthesia; Anesthesia, General; Anesthetics, Inhalation; Cohort Studies; Consciousness | 2014 |
The choice of anaesthetic--sevoflurane or propofol--and outcome from cancer surgery: a retrospective analysis.
Topics: Anesthetics, Inhalation; Anesthetics, Intravenous; Humans; Methyl Ethers; Neoplasms; Propofol; Retro | 2014 |
The choice of anaesthetic--sevoflurane or propofol--and outcome from cancer surgery: a retrospective analysis.
Topics: Anesthetics, Inhalation; Anesthetics, Intravenous; Humans; Methyl Ethers; Neoplasms; Propofol; Retro | 2014 |
The choice of anaesthetic--sevoflurane or propofol--and outcome from cancer surgery: a retrospective analysis.
Topics: Anesthetics, Inhalation; Anesthetics, Intravenous; Humans; Methyl Ethers; Neoplasms; Propofol; Retro | 2014 |
The choice of anaesthetic--sevoflurane or propofol--and outcome from cancer surgery: a retrospective analysis.
Topics: Anesthetics, Inhalation; Anesthetics, Intravenous; Humans; Methyl Ethers; Neoplasms; Propofol; Retro | 2014 |
The choice of anaesthetic--sevoflurane or propofol--and outcome from cancer surgery: a retrospective analysis.
Topics: Anesthetics, Inhalation; Anesthetics, Intravenous; Humans; Methyl Ethers; Neoplasms; Propofol; Retro | 2014 |
The choice of anaesthetic--sevoflurane or propofol--and outcome from cancer surgery: a retrospective analysis.
Topics: Anesthetics, Inhalation; Anesthetics, Intravenous; Humans; Methyl Ethers; Neoplasms; Propofol; Retro | 2014 |
The choice of anaesthetic--sevoflurane or propofol--and outcome from cancer surgery: a retrospective analysis.
Topics: Anesthetics, Inhalation; Anesthetics, Intravenous; Humans; Methyl Ethers; Neoplasms; Propofol; Retro | 2014 |
The choice of anaesthetic--sevoflurane or propofol--and outcome from cancer surgery: a retrospective analysis.
Topics: Anesthetics, Inhalation; Anesthetics, Intravenous; Humans; Methyl Ethers; Neoplasms; Propofol; Retro | 2014 |
The choice of anaesthetic--sevoflurane or propofol--and outcome from cancer surgery: a retrospective analysis.
Topics: Anesthetics, Inhalation; Anesthetics, Intravenous; Humans; Methyl Ethers; Neoplasms; Propofol; Retro | 2014 |
Malignant disease within 5 years after surgery in relation to duration of sevoflurane anesthesia and time with bispectral index under 45.
Topics: Adult; Aged; Anesthetics, Inhalation; Consciousness Monitors; Female; Humans; Incidence; Kaplan-Meie | 2011 |
The importance of being negative.
Topics: Anesthetics, Inhalation; Consciousness Monitors; Female; Humans; Male; Methyl Ethers; Monitoring, In | 2011 |
[The status in the field of malignant tumors in the Mongolian People's Republic (report on an educational sojourn in Ulan-Bator in October - November 1960)].
Topics: Biometry; Humans; Methyl Ethers; Neoplasms; Sevoflurane | 1961 |