Page last updated: 2024-11-04

sevoflurane and Asystole

sevoflurane has been researched along with Asystole in 29 studies

Sevoflurane: A non-explosive inhalation anesthetic used in the induction and maintenance of general anesthesia. It does not cause respiratory irritation and may also prevent PLATELET AGGREGATION.
sevoflurane : An ether compound having fluoromethyl and 1,1,1,3,3,3-hexafluoroisopropyl as the two alkyl groups.

Research Excerpts

ExcerptRelevanceReference
"The addition of sufentanil, even at very low doses, during anesthesia induction with sevoflurane using a single breath technique, may be dangerous because of possible bradycardia and even asystole."9.11[Severe bradycardia and asystole with low dose sufentanil during induction with sevoflurane: a report of three cases]. ( Cardinal, V; Claprood, Y; Colas, MJ; Gagnon, L; Martin, R; Tétrault, JP, 2004)
"A multimodal sevoflurane-based sedation regimen together with targeted temperature management resulted in a lower incidence of delirium and a shorter duration for mechanical ventilation and ICU length of stay than did the treatment with intravenous sedation combined with the classical cooling protocol."8.02A multimodal sevoflurane-based sedation regimen in combination with targeted temperature management in post-cardiac arrest patients reduces the incidence of delirium: An observational propensity score-matched study. ( Algargoush, A; Bos, AT; Foudraine, NA; van Osch, FH, 2021)
"Clonidine is a frequently administered alpha2-adrenergic agonist which can decrease heart rate and blood pressure."5.34Cardiac arrest in a child with cerebral palsy undergoing sevoflurane induction of anesthesia after preoperative clonidine. ( Goldfinger, MM; Tripi, PA, 2007)
"The addition of sufentanil, even at very low doses, during anesthesia induction with sevoflurane using a single breath technique, may be dangerous because of possible bradycardia and even asystole."5.11[Severe bradycardia and asystole with low dose sufentanil during induction with sevoflurane: a report of three cases]. ( Cardinal, V; Claprood, Y; Colas, MJ; Gagnon, L; Martin, R; Tétrault, JP, 2004)
"A multimodal sevoflurane-based sedation regimen together with targeted temperature management resulted in a lower incidence of delirium and a shorter duration for mechanical ventilation and ICU length of stay than did the treatment with intravenous sedation combined with the classical cooling protocol."4.02A multimodal sevoflurane-based sedation regimen in combination with targeted temperature management in post-cardiac arrest patients reduces the incidence of delirium: An observational propensity score-matched study. ( Algargoush, A; Bos, AT; Foudraine, NA; van Osch, FH, 2021)
"Ischemic postconditioning (stutter CPR) and sevoflurane have been shown to mitigate the effects of reperfusion injury in cardiac tissue after 15min of ventricular fibrillation (VF) cardiac arrest."3.81Bundled postconditioning therapies improve hemodynamics and neurologic recovery after 17 min of untreated cardiac arrest. ( Bartos, JA; Bates, FS; Debaty, G; Lurie, KG; Matsuura, TR; McKnite, SH; Metzger, JM; Neumar, RW; Rees, JN; Riess, ML; Sarraf, M; Segal, N; Sloper, DT; Yannopoulos, D; Youngquist, ST, 2015)
" During sevoflurane induction, severe hypotension and laryngospasm resulted in cardiac arrest."3.77Transient cardiac arrest in patient with left ventricular noncompaction (spongiform cardiomyopathy). ( Ito, H; Kawaai, H; Yamazaki, S, 2011)
"Williams-Beuren syndrome is the clinical manifestation of a congenital genetic disorder in the elastin gene, among others."1.48Cardiac arrest related to anaesthesia in Williams-Beuren syndrome. ( Castro Parga, L; Durán la Fuente, P; Gónzalez Rocafort, A; Lucena Delgado, J; Reinoso Barbero, F; Sanabria Carretero, P, 2018)
" In selected patients with meningitis, therapeutic hypothermia may still present a treatment option, and the long-term use of inhalational anesthetics could be appropriate with concomitant intracranial pressure monitoring."1.46Therapeutic hypothermia and inhalation anesthesia in a patient with severe pneumococcal meningitis and secondary cardiac arrest. ( Bukovnik, N; Markota, A; Rebol, J; Sinkovič, A; Velnar, T, 2017)
"Our asphyxia cardiac arrest (ACA) rat model is well established."1.43Anesthesia specific differences in a cardio-pulmonary resuscitation rat model; halothane versus sevoflurane. ( Ebmeyer, U; Esser, T; Keilhoff, G, 2016)
"Asystolic cardiac arrest for 8 minutes was induced in 73 rats with a mixture of potassium chloride and esmolol."1.42Do different anesthesia regimes affect hippocampal apoptosis and neurologic deficits in a rodent cardiac arrest model? ( Bendel, S; Grandgirard, D; Haenggi, M; Jakob, SM; Leib, SL; Pereira, A; Putzu, A; Schlickeiser, J; Springe, D; Takala, J, 2015)
"Successful resuscitation after cardiac arrest is typically associated with cerebral and myocardial ischemia/reperfusion (I/R)-injury."1.38Hypothermia and anesthetic postconditioning influence the expression and activity of small intestinal proteins possibly involved in ischemia/reperfusion-mediated events following cardiopulmonary resuscitation. ( Albrecht, M; Bein, B; Gruenewald, M; Meybohm, P; Scholz, J; Zacharowski, K; Zitta, K, 2012)
"Bupivacaine was intravenously infused at a rate of 1, 4, or 16 mg/kg/min (groups A, B, and C, respectively) until mean arterial pressure (MAP) dropped to 50% of initial value."1.37Influence of bupivacaine injection dose rate on cardiovascular depression, subsequent hemodynamic course, and related bupivacaine plasma levels in piglets. ( Bettschart-Wolfensberger, R; Dave, MH; Kutter, AP; Martin Jurado, O; Mauch, J; Spielmann, N; Weiss, M, 2011)
"Twenty-two pigs were subjected to cardiac arrest."1.37Pharmacological postconditioning with sevoflurane after cardiopulmonary resuscitation reduces myocardial dysfunction. ( Albrecht, M; Bein, B; Foesel, N; Gruenewald, M; Maracke, M; Meybohm, P; Müller, C; Scholz, J; Schrezenmeir, J; Tacke, S; Zitta, K, 2011)
"Acquired long QT syndrome is a rare condition whose diagnosis is of vital importance given the risk of torsade de pointes and sudden death."1.36[Perioperative acquired long QT syndrome: a case report]. ( Arizaga, A; Goitia, L; Pérez, P; Sebastián, P; Taibo, JM, 2010)
"Clonidine is a frequently administered alpha2-adrenergic agonist which can decrease heart rate and blood pressure."1.34Cardiac arrest in a child with cerebral palsy undergoing sevoflurane induction of anesthesia after preoperative clonidine. ( Goldfinger, MM; Tripi, PA, 2007)
"Deaths resulting from arrhythmia appeared to correlate with left ventricular mass indices >350 g x m(-2)."1.34Cardiac arrhythmias following anesthesia induction in infantile-onset Pompe disease: a case series. ( Corzo, D; Dearmey, SM; Kishnani, PS; Li, JS; Mackey, JF; Morgan, C; Ross, AK; Wang, LY; Worden, M, 2007)

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (6.90)18.2507
2000's10 (34.48)29.6817
2010's14 (48.28)24.3611
2020's3 (10.34)2.80

Authors

AuthorsStudies
Foudraine, NA1
Algargoush, A1
van Osch, FH1
Bos, AT1
Noordergraaf, GJ1
Hendriksen, E1
Peluso, L1
Legros, B1
Caroyer, S1
Taccone, FS1
Gaspard, N1
Lucena Delgado, J1
Sanabria Carretero, P1
Durán la Fuente, P1
Gónzalez Rocafort, A1
Castro Parga, L1
Reinoso Barbero, F1
Knapp, J1
Teschendorf, P1
Scholz, E1
Roewer, J1
Russ, N1
Böttiger, BW1
Popp, E1
Bartos, JA1
Matsuura, TR1
Sarraf, M1
Youngquist, ST1
McKnite, SH1
Rees, JN1
Sloper, DT1
Bates, FS1
Segal, N1
Debaty, G1
Lurie, KG1
Neumar, RW1
Metzger, JM1
Riess, ML1
Yannopoulos, D1
Bendel, S1
Springe, D1
Pereira, A1
Grandgirard, D1
Leib, SL1
Putzu, A1
Schlickeiser, J1
Jakob, SM1
Takala, J1
Haenggi, M1
Orr, TM1
Orr, DL1
Franzini, S1
Neri, S1
Esser, T1
Keilhoff, G1
Ebmeyer, U1
Bukovnik, N1
Markota, A1
Velnar, T1
Rebol, J1
Sinkovič, A1
Uejima, T1
Leclerc, C1
Rouaud, J1
Goitia, L1
Pérez, P1
Sebastián, P1
Taibo, JM1
Arizaga, A1
Haberstroh, J1
Eberspächer, E1
Becker, K1
Henke, J1
Sager, M1
Arras, M1
Yamazaki, S1
Ito, H1
Kawaai, H1
Mauch, J1
Kutter, AP1
Martin Jurado, O1
Spielmann, N1
Dave, MH1
Bettschart-Wolfensberger, R1
Weiss, M1
Albrecht, M2
Gruenewald, M2
Zitta, K2
Zacharowski, K1
Scholz, J2
Bein, B2
Meybohm, P2
Müller, C1
Foesel, N1
Maracke, M1
Tacke, S1
Schrezenmeir, J1
Saricaoğlu, F1
Dal, D1
Cardinal, V1
Martin, R1
Tétrault, JP1
Colas, MJ1
Gagnon, L1
Claprood, Y1
Somerville, NS1
Mearns, C1
Chin, C1
Blaney, S1
Anderson, D1
Girshin, M1
Mukherjee, J1
Clowney, R1
Singer, LP1
Wasnick, J1
Goldfinger, MM1
Tripi, PA1
Wang, LY1
Ross, AK1
Li, JS1
Dearmey, SM1
Mackey, JF1
Worden, M1
Corzo, D1
Morgan, C1
Kishnani, PS1
Gardner, JC1
Turner, CS1
Ririe, DG1
Hall, JE1
Oldham, TA1
Stewart, JI1
Harmer, M1
Wang, J1
Winship, S1
Russell, G1
Kurdi, O1
Deleuze, A1
Marret, E1
Bonnet, F1

Clinical Trials (4)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Randomized Triple-blind Placebo Controlled Trial of Influence of Morphine or Ketamine or Saline Applied During In-hospital Cardiopulmonary Resuscitation on Early Survival and Neurological Outcome[NCT04009759]Phase 1240 participants (Anticipated)Interventional2021-10-01Not yet recruiting
Digestive ENdoscopy afTeR Out-of-hospitAl Cardiac arresT[NCT02349074]221 participants (Actual)Interventional2014-11-12Completed
Low Dose Fentanyl/Midazolam Improves Sevoflurane Induction in Adults[NCT00723164]80 participants (Actual)Interventional2005-10-31Completed
Comparison of Intubation Conditions After Induction With Propofol Associated With a Dose of Remifentanil or Sufentanil in Surgical Tooth Extraction.[NCT01910285]Phase 470 participants (Actual)Interventional2013-06-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

2 trials available for sevoflurane and Asystole

ArticleYear
[Severe bradycardia and asystole with low dose sufentanil during induction with sevoflurane: a report of three cases].
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2004, Volume: 51, Issue:8

    Topics: Adult; Anesthetics, Combined; Anesthetics, Inhalation; Anesthetics, Intravenous; Atropine; Bradycard

2004
Comparison between halothane and sevoflurane for adult vital capacity induction.
    British journal of anaesthesia, 1997, Volume: 79, Issue:3

    Topics: Adolescent; Adult; Aged; Anesthesia, Inhalation; Anesthetics, Inhalation; Double-Blind Method; Ether

1997

Other Studies

27 other studies available for sevoflurane and Asystole

ArticleYear
A multimodal sevoflurane-based sedation regimen in combination with targeted temperature management in post-cardiac arrest patients reduces the incidence of delirium: An observational propensity score-matched study.
    Resuscitation, 2021, Volume: 159

    Topics: Delirium; Heart Arrest; Humans; Hypnotics and Sedatives; Hypothermia, Induced; Incidence; Intensive

2021
Not a whiff: Sevoflurane for post-ROSC sedation on the ICU. Try it, you might like it.
    Resuscitation, 2021, Volume: 159

    Topics: Delirium; Heart Arrest; Humans; Hypothermia, Induced; Incidence; Intensive Care Units; Methyl Ethers

2021
Falsely predictive EEG and clinical signs after post-anoxic brain injury under sevoflurane anesthesia.
    Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology, 2021, Volume: 132, Issue:5

    Topics: Adult; Anesthetics, Inhalation; Electroencephalography; Female; Heart Arrest; Humans; Hypoxia-Ischem

2021
Cardiac arrest related to anaesthesia in Williams-Beuren syndrome.
    Revista espanola de anestesiologia y reanimacion, 2018, Volume: 65, Issue:4

    Topics: Anesthesia, Inhalation; Anesthetics, Inhalation; Aortic Stenosis, Supravalvular; Arteries; Bradycard

2018
Conductance catheter measurement and effect of different anesthetics in a rat model of postresuscitation myocardial dysfunction.
    Journal of the American Association for Laboratory Animal Science : JAALAS, 2014, Volume: 53, Issue:4

    Topics: Anesthetics; Animals; Cardiopulmonary Resuscitation; Disease Models, Animal; Heart Arrest; Heart Fun

2014
Bundled postconditioning therapies improve hemodynamics and neurologic recovery after 17 min of untreated cardiac arrest.
    Resuscitation, 2015, Volume: 87

    Topics: Anesthetics, Inhalation; Animals; Cardiopulmonary Resuscitation; Coronary Circulation; Disease Model

2015
Do different anesthesia regimes affect hippocampal apoptosis and neurologic deficits in a rodent cardiac arrest model?
    BMC anesthesiology, 2015, Jan-15, Volume: 15

    Topics: Anesthetics; Animals; Apoptosis; Fentanyl; Heart Arrest; Hippocampus; Ketamine; Male; Medetomidine;

2015
Pulseless Ventricular Tachycardia During Office-Based Anesthetic in a Four-Year-Old Child.
    Anesthesia progress, 2015,Winter, Volume: 62, Issue:4

    Topics: Advanced Cardiac Life Support; Anesthesia, Dental; Anesthesia, Inhalation; Anesthetics, Inhalation;

2015
Sevoflurane during CPR for intraoperative cardiac arrest: To discontinue or to maintain?
    Resuscitation, 2016, Volume: 106

    Topics: Adult; Cardiopulmonary Resuscitation; Child, Preschool; Female; Heart Arrest; Humans; Intraoperative

2016
Anesthesia specific differences in a cardio-pulmonary resuscitation rat model; halothane versus sevoflurane.
    Brain research, 2016, 12-01, Volume: 1652

    Topics: Anesthetics, Inhalation; Animals; Asphyxia; CA1 Region, Hippocampal; Cardiopulmonary Resuscitation;

2016
Therapeutic hypothermia and inhalation anesthesia in a patient with severe pneumococcal meningitis and secondary cardiac arrest.
    The American journal of emergency medicine, 2017, Volume: 35, Issue:4

    Topics: Adrenal Cortex Hormones; Anesthesia, Inhalation; Anesthetics, Inhalation; Anti-Bacterial Agents; Dra

2017
Sevoflurane for intubation of neonates.
    Paediatric anaesthesia, 2008, Volume: 18, Issue:9

    Topics: Anesthetics, Intravenous; Heart Arrest; Humans; Infant, Newborn; Infant, Premature; Intubation, Intr

2008
[Asystole and severe bradycardia induced by sevoflurane associated with alfentanil in adults].
    Annales francaises d'anesthesie et de reanimation, 2009, Volume: 28, Issue:4

    Topics: Adult; Alfentanil; Anesthesia, Dental; Anticonvulsants; Bradycardia; Drug Synergism; Epilepsy; Heart

2009
[Perioperative acquired long QT syndrome: a case report].
    Revista espanola de anestesiologia y reanimacion, 2010, Volume: 57, Issue:2

    Topics: Adjuvants, Anesthesia; Adrenergic beta-Antagonists; Amoxicillin-Potassium Clavulanate Combination; A

2010
Response of the Committee for Anaesthesia, Analgesia and Pain Prophylaxis of the Society for Laboratory Animal Science to 'Temporary inhalation anaesthesia in experimental pigs'.
    Laboratory animals, 2011, Volume: 45, Issue:2

    Topics: Analgesia; Anesthesia, Inhalation; Animals; Dose-Response Relationship, Drug; Heart Arrest; Hypercap

2011
Transient cardiac arrest in patient with left ventricular noncompaction (spongiform cardiomyopathy).
    Anesthesia progress, 2011,Spring, Volume: 58, Issue:1

    Topics: Anesthesia, Dental; Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intravenous; Cardiomy

2011
Influence of bupivacaine injection dose rate on cardiovascular depression, subsequent hemodynamic course, and related bupivacaine plasma levels in piglets.
    Journal of anesthesia, 2011, Volume: 25, Issue:5

    Topics: Anesthetics, Local; Animals; Blood Pressure; Bupivacaine; Cardiovascular System; Depression, Chemica

2011
Hypothermia and anesthetic postconditioning influence the expression and activity of small intestinal proteins possibly involved in ischemia/reperfusion-mediated events following cardiopulmonary resuscitation.
    Resuscitation, 2012, Volume: 83, Issue:1

    Topics: Anesthesia, Inhalation; Anesthetics, Inhalation; Animals; Biomarkers; Blotting, Western; Cardiopulmo

2012
Pharmacological postconditioning with sevoflurane after cardiopulmonary resuscitation reduces myocardial dysfunction.
    Critical care (London, England), 2011, Volume: 15, Issue:5

    Topics: Animals; Cardiopulmonary Resuscitation; Cardiotonic Agents; Disease Models, Animal; Heart Arrest; Me

2011
Cardiac arrest in a patient with Larsen syndrome under sevoflurane anesthesia.
    Paediatric anaesthesia, 2004, Volume: 14, Issue:10

    Topics: Abnormalities, Multiple; Anesthesia, Inhalation; Anesthetics, Inhalation; Child; Fatal Outcome; Hear

2004
Anesthetic management of the complications of previously undiagnosed ingested foreign body in a pediatric patient.
    Paediatric anaesthesia, 2004, Volume: 14, Issue:12

    Topics: Airway Obstruction; Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Local; Apnea; Atracur

2004
The postoperative cardiovascular arrest of a 5-year-old male: an initial presentation of Duchenne's muscular dystrophy.
    Paediatric anaesthesia, 2006, Volume: 16, Issue:2

    Topics: Anesthesia; Anesthetics, Inhalation; Anesthetics, Intravenous; Blood Gas Analysis; Cardiopulmonary R

2006
Cardiac arrest in a child with cerebral palsy undergoing sevoflurane induction of anesthesia after preoperative clonidine.
    Paediatric anaesthesia, 2007, Volume: 17, Issue:3

    Topics: Adrenergic alpha-Agonists; Anesthesia, General; Anesthetics, Inhalation; Cerebral Palsy; Child, Pres

2007
Cardiac arrhythmias following anesthesia induction in infantile-onset Pompe disease: a case series.
    Paediatric anaesthesia, 2007, Volume: 17, Issue:8

    Topics: alpha-Glucosidases; Anesthesia, General; Anesthetics, Intravenous; Arrhythmias, Cardiac; Clinical Tr

2007
Vagal hypertonia and anesthesia in Angelman syndrome.
    Paediatric anaesthesia, 2008, Volume: 18, Issue:4

    Topics: Adrenergic Agonists; Anaphylaxis; Androstanols; Anesthesia; Anesthetics, Inhalation; Anesthetics, In

2008
Induction of anaesthesia with sevoflurane and low-dose remifentanil: asystole following laryngoscopy.
    British journal of anaesthesia, 1998, Volume: 81, Issue:6

    Topics: Aged; Analgesics, Opioid; Anesthetics, Inhalation; Heart Arrest; Humans; Male; Methyl Ethers; Piperi

1998
Induction of anaesthesia with sevoflurane and low-dose remifentanil: asystole following laryngoscopy.
    British journal of anaesthesia, 1998, Volume: 81, Issue:6

    Topics: Aged; Analgesics, Opioid; Anesthetics, Inhalation; Heart Arrest; Humans; Male; Methyl Ethers; Piperi

1998
Induction of anaesthesia with sevoflurane and low-dose remifentanil: asystole following laryngoscopy.
    British journal of anaesthesia, 1998, Volume: 81, Issue:6

    Topics: Aged; Analgesics, Opioid; Anesthetics, Inhalation; Heart Arrest; Humans; Male; Methyl Ethers; Piperi

1998
Induction of anaesthesia with sevoflurane and low-dose remifentanil: asystole following laryngoscopy.
    British journal of anaesthesia, 1998, Volume: 81, Issue:6

    Topics: Aged; Analgesics, Opioid; Anesthetics, Inhalation; Heart Arrest; Humans; Male; Methyl Ethers; Piperi

1998
Asystole during anaesthetic induction with remifentanil and sevoflurane.
    British journal of anaesthesia, 2001, Volume: 87, Issue:6

    Topics: Aged; Anesthetics, Combined; Anesthetics, Inhalation; Anesthetics, Intravenous; Heart Arrest; Humans

2001