Page last updated: 2024-11-04

sevoflurane and Anoxia-Ischemia, Brain

sevoflurane has been researched along with Anoxia-Ischemia, Brain in 17 studies

Sevoflurane: A non-explosive inhalation anesthetic used in the induction and maintenance of general anesthesia. It does not cause respiratory irritation and may also prevent PLATELET AGGREGATION.
sevoflurane : An ether compound having fluoromethyl and 1,1,1,3,3,3-hexafluoroisopropyl as the two alkyl groups.

Research Excerpts

ExcerptRelevanceReference
"Sevoflurane can produce delayed protection against cerebral ischemia-reperfusion injury by down-regulating TNF-alpha, IL-1beta protein, and mRNA expression."3.75[Sevoflurane preconditioning induced delayed neuroprotection against focal cerebral ischemia in rats]. ( Guo, Q; Pan, Y; Shi, M; Wang, E; Ye, Z, 2009)
"Sevoflurane post-treatment decreased G9a and H3K9me2 levels, and G9a level was negatively correlated with NRF2 level."1.62Post-Treatment Sevoflurane Protects Against Hypoxic-Ischemic Brain Injury in Neonatal Rats by Downregulating Histone Methyltransferase G9a and Upregulating Nuclear Factor Erythroid 2-Related Factor 2 (NRF2). ( Li, X; Wang, H; Xu, Y; Zhang, H; Zhu, S, 2021)
"Williams-Beuren syndrome is the clinical manifestation of a congenital genetic disorder in the elastin gene, among others."1.48Cardiac arrest related to anaesthesia in Williams-Beuren syndrome. ( Castro Parga, L; Durán la Fuente, P; Gónzalez Rocafort, A; Lucena Delgado, J; Reinoso Barbero, F; Sanabria Carretero, P, 2018)
"Sevoflurane is a volatile anesthetic agent that reduces cerebral metabolism and thereby may reduce neuronal damage during energy deprivation."1.31Sevoflurane improves electrophysiological recovery of rat hippocampal slice CA1 pyramidal neurons after hypoxia. ( Cottrell, JE; Kass, IS; Matei, G; McCadden, T; Pavlik, R, 2002)

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (23.53)29.6817
2010's6 (35.29)24.3611
2020's7 (41.18)2.80

Authors

AuthorsStudies
Niu, J2
Wu, Z2
Xue, H4
Zhang, Y2
Gao, Q2
Li, C2
Zhao, P4
Shan, W1
Wu, Y1
Han, X1
Chen, Q1
Wu, J1
Zhang, YH1
Gao, QS1
Wu, ZY1
Niu, JY1
Peluso, L1
Legros, B1
Caroyer, S1
Taccone, FS1
Gaspard, N1
Çolak, R1
Celik, A1
Diniz, G1
Alkan Özdemir, S1
Yilmaz, O1
Calkavur, S1
Wang, H1
Xu, Y2
Zhu, S1
Li, X1
Zhang, H1
Lucena Delgado, J1
Sanabria Carretero, P1
Durán la Fuente, P1
Gónzalez Rocafort, A1
Castro Parga, L1
Reinoso Barbero, F1
Wang, S1
Ren, X1
Wang, Z1
Ma, H1
Zuo, Z1
Lin, EP1
Miles, L2
Hughes, EA1
McCann, JC1
Vorhees, CV2
McAuliffe, JJ2
Loepke, AW2
Lai, Z1
Zhang, L1
Su, J1
Cai, D1
Xu, Q1
Ye, Z1
Guo, Q1
Wang, E1
Shi, M1
Pan, Y1
Joseph, B1
Hughes, E1
Yang, T1
Zhuang, L1
Rei Fidalgo, AM1
Petrides, E1
Terrando, N1
Wu, X1
Sanders, RD1
Robertson, NJ1
Johnson, MR1
Maze, M1
Ma, D1
Matei, G1
Pavlik, R1
McCadden, T1
Cottrell, JE1
Kass, IS1
Kehl, F1
Payne, RS1
Roewer, N1
Schurr, A1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Delirium Reduction by Volatile Anesthesia in Cardiac Surgery: Prospective, Randomized, Single-blinded Study[NCT03729011]Phase 4672 participants (Anticipated)Interventional2019-01-09Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

17 other studies available for sevoflurane and Anoxia-Ischemia, Brain

ArticleYear
Sevoflurane post-conditioning alleviated hypoxic-ischemic brain injury in neonatal rats by inhibiting endoplasmic reticulum stress-mediated autophagy via IRE1 signalings.
    Neurochemistry international, 2021, Volume: 150

    Topics: Animals; Animals, Newborn; Autophagy; Endoplasmic Reticulum Stress; Hypoxia-Ischemia, Brain; Ischemi

2021
The mechanism of sevoflurane post-treatment alleviating hypoxic-ischemic encephalopathy by affecting histone methyltransferase G9a in rats.
    Bioengineered, 2021, Volume: 12, Issue:2

    Topics: Animals; Cerebral Cortex; Gene Expression Regulation, Enzymologic; Histone-Lysine N-Methyltransferas

2021
Sevoflurane Post-Conditioning Ameliorates Neuronal Deficits and Axon Demyelination After Neonatal Hypoxic Ischemic Brain Injury: Role of Microglia/Macrophage.
    Cellular and molecular neurobiology, 2021, Volume: 41, Issue:8

    Topics: Animals; Animals, Newborn; Axons; Brain; Demyelinating Diseases; Female; Hypoxia-Ischemia, Brain; Is

2021
Falsely predictive EEG and clinical signs after post-anoxic brain injury under sevoflurane anesthesia.
    Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology, 2021, Volume: 132, Issue:5

    Topics: Adult; Anesthetics, Inhalation; Electroencephalography; Female; Heart Arrest; Humans; Hypoxia-Ischem

2021
Evaluation of the Neuroprotective Effect of Pycnogenol in a Hypoxic-Ischemic Brain Injury Model in Newborn Rats.
    American journal of perinatology, 2023, Volume: 40, Issue:6

    Topics: Animals; Animals, Newborn; Brain; Brain Injuries; Hypoxia-Ischemia, Brain; Neuroprotective Agents; R

2023
Post-Treatment Sevoflurane Protects Against Hypoxic-Ischemic Brain Injury in Neonatal Rats by Downregulating Histone Methyltransferase G9a and Upregulating Nuclear Factor Erythroid 2-Related Factor 2 (NRF2).
    Medical science monitor : international medical journal of experimental and clinical research, 2021, Jun-01, Volume: 27

    Topics: Animals; Animals, Newborn; Behavior, Animal; Cerebral Infarction; Disease Models, Animal; Gene Expre

2021
Sevoflurane Postconditioning Ameliorates Neuronal Migration Disorder Through Reelin/Dab1 and Improves Long-term Cognition in Neonatal Rats After Hypoxic-Ischemic Injury.
    Neurotoxicity research, 2021, Volume: 39, Issue:5

    Topics: Adaptor Proteins, Signal Transducing; Animals; Animals, Newborn; Cell Movement; Cognition; Hypoxia-I

2021
Cardiac arrest related to anaesthesia in Williams-Beuren syndrome.
    Revista espanola de anestesiologia y reanimacion, 2018, Volume: 65, Issue:4

    Topics: Anesthesia, Inhalation; Anesthetics, Inhalation; Aortic Stenosis, Supravalvular; Arteries; Bradycard

2018
Sevoflurane Postconditioning Inhibits Autophagy Through Activation of the Extracellular Signal-Regulated Kinase Cascade, Alleviating Hypoxic-Ischemic Brain Injury in Neonatal Rats.
    Neurochemical research, 2019, Volume: 44, Issue:2

    Topics: Animals; Autophagy; Brain; Brain Injuries; Extracellular Signal-Regulated MAP Kinases; Hypoxia-Ische

2019
Sevoflurane postconditioning provides neuroprotection against brain hypoxia-ischemia in neonatal rats.
    Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2014, Volume: 35, Issue:9

    Topics: Analysis of Variance; Animals; Animals, Newborn; Body Weight; Decanoic Acids; Dose-Response Relation

2014
A combination of mild hypothermia and sevoflurane affords long-term protection in a modified neonatal mouse model of cerebral hypoxia-ischemia.
    Anesthesia and analgesia, 2014, Volume: 119, Issue:5

    Topics: Anesthetics, Inhalation; Animals; Animals, Newborn; Brain; Cognition; Female; Hypothermia, Induced;

2014
Sevoflurane postconditioning improves long-term learning and memory of neonatal hypoxia-ischemia brain damage rats via the PI3K/Akt-mPTP pathway.
    Brain research, 2016, Jan-01, Volume: 1630

    Topics: Animals; Cell Death; Disease Models, Animal; Female; Hippocampus; Hypoxia-Ischemia, Brain; Ischemic

2016
[Sevoflurane preconditioning induced delayed neuroprotection against focal cerebral ischemia in rats].
    Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences, 2009, Volume: 34, Issue:2

    Topics: Animals; Hypoxia-Ischemia, Brain; Infarction, Middle Cerebral Artery; Interleukin-1beta; Ischemic Pr

2009
Desflurane, isoflurane, and sevoflurane provide limited neuroprotection against neonatal hypoxia-ischemia in a delayed preconditioning paradigm.
    Anesthesiology, 2009, Volume: 111, Issue:3

    Topics: Anesthetics, Inhalation; Animals; Animals, Newborn; Apomorphine; Behavior, Animal; Blood Gas Analysi

2009
Xenon and sevoflurane provide analgesia during labor and fetal brain protection in a perinatal rat model of hypoxia-ischemia.
    PloS one, 2012, Volume: 7, Issue:5

    Topics: Analgesia; Animals; Animals, Newborn; Apoptosis; Brain; Caspase 3; Cell Survival; Cohort Studies; Fe

2012
Sevoflurane improves electrophysiological recovery of rat hippocampal slice CA1 pyramidal neurons after hypoxia.
    Journal of neurosurgical anesthesiology, 2002, Volume: 14, Issue:4

    Topics: Anesthetics, Inhalation; Animals; Dose-Response Relationship, Drug; Electrophysiology; Evoked Potent

2002
Sevoflurane-induced preconditioning of rat brain in vitro and the role of KATP channels.
    Brain research, 2004, Sep-17, Volume: 1021, Issue:1

    Topics: Adenosine Triphosphate; Anesthetics, Inhalation; Animals; Decanoic Acids; Dose-Response Relationship

2004