sevoflurane has been researched along with Allodynia in 14 studies
Sevoflurane: A non-explosive inhalation anesthetic used in the induction and maintenance of general anesthesia. It does not cause respiratory irritation and may also prevent PLATELET AGGREGATION.
sevoflurane : An ether compound having fluoromethyl and 1,1,1,3,3,3-hexafluoroisopropyl as the two alkyl groups.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Two hundred and fourteen women undergoing breast cancer surgery under remifentanil-based general anaesthesia were randomly included in this prospective and double-blind trial." | 9.14 | Maintenance anaesthetics during remifentanil-based anaesthesia might affect postoperative pain control after breast cancer surgery. ( Byeon, GJ; Cho, AR; Kim, HJ; Kim, KH; Kwon, JY; Lee, HJ; Shin, SW; Yoon, JW, 2010) |
| "Two hundred and fourteen women undergoing breast cancer surgery under remifentanil-based general anaesthesia were randomly included in this prospective and double-blind trial." | 5.14 | Maintenance anaesthetics during remifentanil-based anaesthesia might affect postoperative pain control after breast cancer surgery. ( Byeon, GJ; Cho, AR; Kim, HJ; Kim, KH; Kwon, JY; Lee, HJ; Shin, SW; Yoon, JW, 2010) |
| "Hyperalgesia was not detected 3 or 7 days after the administration of remifentanil." | 2.94 | Determination of acute tolerance and hyperalgesia to remifentanil constant rate infusion in dogs undergoing sevoflurane anaesthesia. ( Domínguez, JM; Fernández-Sarmiento, JA; Gómez-Villamandos, RJ; Granados, MM; Morgaz, J; Muñoz-Rascón, P; Navarrete-Calvo, R; Quirós-Carmona, S; Ruíz-López, P, 2020) |
| "Postoperative pain was managed by sufentanil titration in the postanesthetic care unit, followed by sufentanil infusion via patient-controlled analgesia." | 2.84 | Preoperative But Not Postoperative Flurbiprofen Axetil Alleviates Remifentanil-induced Hyperalgesia After Laparoscopic Gynecological Surgery: A Prospective, Randomized, Double-blinded, Trial. ( Li, Y; Shu, R; Wang, C; Wang, G; Wang, H; Yu, Y; Zhang, L; Zhao, Q, 2017) |
| "Opioid-induced hyperalgesia was defined as an increase in mechanical nociceptive thresholds after opioid administration." | 1.42 | Amitriptyline, minocycline and maropitant reduce the sevoflurane minimum alveolar concentration and potentiate remifentanil but do not prevent acute opioid tolerance and hyperalgesia in the rat: a randomised laboratory study. ( Abreu, M; Aguado, D; Benito, J; García-Fernández, J; Gómez de Segura, IA, 2015) |
| "Opioid-induced hyperalgesia was associated with an increase in the MAC in normal rats who had not undergone surgery." | 1.42 | Hyperalgesia and increased sevoflurane minimum alveolar concentration induced by opioids in the rat: a randomised experimental study. ( Abreu, M; Aguado, D; Benito, J; García-Fernández, J; Segura, IA, 2015) |
| "Tramadol-induced hyperalgesia in the rat lasted for several weeks and was associated with an increase in the MAC of sevoflurane." | 1.42 | Tramadol-induced hyperalgesia and its prevention by ketamine in rats: A randomised experimental study. ( Abreu, M; Aguado, D; Benito, J; García-Fernández, J; Gómez de Segura, IA, 2015) |
| "Hyperalgesia was considered to be a decrease in mechanical thresholds, whereas opioid tolerance was considered to be a decrease in sevoflurane MAC reduction by remifentanil." | 1.39 | Effects of naloxone on opioid-induced hyperalgesia and tolerance to remifentanil under sevoflurane anesthesia in rats. ( Abreu, M; Aguado, D; Benito, J; Garcia-Fernandez, J; Gómez de Segura, IA, 2013) |
| "Gabapentin has been shown to be effective in reducing postoperative narcotic usage, a reduction that may be associated with a reduction in opioid-induced tolerance and hyperalgesia." | 1.38 | The effects of gabapentin on acute opioid tolerance to remifentanil under sevoflurane anesthesia in rats. ( Abreu, M; Aguado, D; Benito, J; Garcia-Fernandez, J; Gómez de Segura, IA, 2012) |
| "Sevoflurane effects on opioid-induced hyperalgesia have not been yet evaluated in vivo." | 1.35 | Effects of sevoflurane on carrageenan- and fentanyl-induced pain hypersensitivity in Sprague-Dawley rats. ( Janvier, G; Laulin, JP; Maurette, P; Richebé, P; Rivalan, B; Rivat, C; Simonnet, G, 2009) |
| "However, halothane-induced hyperalgesia during learning clouds interpreting enhanced retention performance solely as a memory consolidation effect." | 1.33 | Memory enhancing effect of low-dose sevoflurane does not occur in basolateral amygdala-lesioned rats. ( Alkire, MT; McReynolds, JR; Nathan, SV, 2005) |
| "Opioid-induced hyperalgesia has been demonstrated in awake animals." | 1.32 | Questioning the cardiocirculatory excitatory effects of opioids under volatile anaesthesia. ( Boulanger, V; Collet, V; De Kock, M; Docquier, MA; Lavand'homme, P, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (28.57) | 29.6817 |
| 2010's | 8 (57.14) | 24.3611 |
| 2020's | 2 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Su, X | 1 |
| Zhu, W | 1 |
| Tian, Y | 1 |
| Tan, L | 1 |
| Wu, H | 1 |
| Wu, L | 1 |
| Ruíz-López, P | 1 |
| Navarrete-Calvo, R | 1 |
| Morgaz, J | 1 |
| Domínguez, JM | 1 |
| Quirós-Carmona, S | 1 |
| Muñoz-Rascón, P | 1 |
| Gómez-Villamandos, RJ | 1 |
| Fernández-Sarmiento, JA | 1 |
| Granados, MM | 1 |
| Aguado, D | 5 |
| Abreu, M | 5 |
| Benito, J | 6 |
| Garcia-Fernandez, J | 5 |
| Gómez de Segura, IA | 5 |
| Segura, IA | 1 |
| Zhang, L | 1 |
| Shu, R | 1 |
| Zhao, Q | 1 |
| Li, Y | 1 |
| Wang, C | 1 |
| Wang, H | 1 |
| Yu, Y | 1 |
| Wang, G | 1 |
| Ruiz-Pérez, D | 1 |
| Largo, C | 1 |
| Polo, G | 1 |
| Canfrán, S | 1 |
| Richebé, P | 1 |
| Rivalan, B | 1 |
| Rivat, C | 1 |
| Laulin, JP | 1 |
| Janvier, G | 1 |
| Maurette, P | 1 |
| Simonnet, G | 1 |
| Shin, SW | 1 |
| Cho, AR | 1 |
| Lee, HJ | 1 |
| Kim, HJ | 1 |
| Byeon, GJ | 1 |
| Yoon, JW | 1 |
| Kim, KH | 1 |
| Kwon, JY | 1 |
| Docquier, MA | 1 |
| Lavand'homme, P | 1 |
| Boulanger, V | 1 |
| Collet, V | 1 |
| De Kock, M | 1 |
| Weber, NC | 1 |
| Toma, O | 1 |
| Awan, S | 1 |
| Frässdorf, J | 1 |
| Preckel, B | 1 |
| Schlack, W | 1 |
| Alkire, MT | 1 |
| Nathan, SV | 1 |
| McReynolds, JR | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effect of Ultra-low Dose Naloxone on Remifentanil-Induced Hyperalgesia[NCT03066739] | Phase 2 | 105 participants (Anticipated) | Interventional | 2023-02-25 | Recruiting | ||
| A Prospective Study Comparing Total Intravenous Anesthesia With Propofol and Remifentanil vs. Propofol and Dexmedetomidine in Adolescent Idiopathic Scoliosis Patients Undergoing Posterior Spinal Fusion and Instrumentation[NCT06096181] | Phase 2 | 120 participants (Anticipated) | Interventional | 2023-12-31 | Not yet recruiting | ||
| [NCT02495363] | 50 participants (Actual) | Observational | 2015-03-31 | Completed | |||
| Development of Pharmacokinetic / Pharmacodynamic (pk/pd) Model of Propofol in Patients With Severe Burns[NCT03704285] | 15 participants (Actual) | Observational | 2018-09-29 | Terminated (stopped due to Outbreak COVID 19) | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 trials available for sevoflurane and Allodynia
| Article | Year |
|---|---|
Regulatory effects of propofol on high-dose remifentanil-induced hyperalgesia.
Topics: Adult; Analgesics, Opioid; Anesthetics, Inhalation; Anesthetics, Intravenous; Cholecystectomy, Lapar | 2020 |
Determination of acute tolerance and hyperalgesia to remifentanil constant rate infusion in dogs undergoing sevoflurane anaesthesia.
Topics: Analgesics, Opioid; Anesthetics, Inhalation; Animals; Cross-Over Studies; Dog Diseases; Dogs; Drug T | 2020 |
Preoperative But Not Postoperative Flurbiprofen Axetil Alleviates Remifentanil-induced Hyperalgesia After Laparoscopic Gynecological Surgery: A Prospective, Randomized, Double-blinded, Trial.
Topics: Adult; Analgesics, Opioid; Anesthetics, Intravenous; Anti-Inflammatory Agents, Non-Steroidal; Female | 2017 |
Maintenance anaesthetics during remifentanil-based anaesthesia might affect postoperative pain control after breast cancer surgery.
Topics: Adult; Aged; Analgesics, Opioid; Anesthetics, Inhalation; Anesthetics, Intravenous; Breast Neoplasms | 2010 |
Maintenance anaesthetics during remifentanil-based anaesthesia might affect postoperative pain control after breast cancer surgery.
Topics: Adult; Aged; Analgesics, Opioid; Anesthetics, Inhalation; Anesthetics, Intravenous; Breast Neoplasms | 2010 |
Maintenance anaesthetics during remifentanil-based anaesthesia might affect postoperative pain control after breast cancer surgery.
Topics: Adult; Aged; Analgesics, Opioid; Anesthetics, Inhalation; Anesthetics, Intravenous; Breast Neoplasms | 2010 |
Maintenance anaesthetics during remifentanil-based anaesthesia might affect postoperative pain control after breast cancer surgery.
Topics: Adult; Aged; Analgesics, Opioid; Anesthetics, Inhalation; Anesthetics, Intravenous; Breast Neoplasms | 2010 |
10 other studies available for sevoflurane and Allodynia
| Article | Year |
|---|---|
Effects of naloxone on opioid-induced hyperalgesia and tolerance to remifentanil under sevoflurane anesthesia in rats.
Topics: Analgesics, Opioid; Anesthesia, Inhalation; Anesthetics, Inhalation; Animals; Behavior, Animal; Drug | 2013 |
Amitriptyline, minocycline and maropitant reduce the sevoflurane minimum alveolar concentration and potentiate remifentanil but do not prevent acute opioid tolerance and hyperalgesia in the rat: a randomised laboratory study.
Topics: Amitriptyline; Analgesics, Opioid; Anesthetics, Inhalation; Animals; Behavior, Animal; Dose-Response | 2015 |
Hyperalgesia and increased sevoflurane minimum alveolar concentration induced by opioids in the rat: a randomised experimental study.
Topics: Analgesics, Opioid; Anesthetics, Inhalation; Animals; Behavior, Animal; Buprenorphine; Hyperalgesia; | 2015 |
Tramadol-induced hyperalgesia and its prevention by ketamine in rats: A randomised experimental study.
Topics: Analgesics; Analgesics, Opioid; Anesthetics, Inhalation; Animals; Hyperalgesia; Ketamine; Male; Meth | 2015 |
Metamizole (dipyrone) effects on sevoflurane requirements and postoperative hyperalgesia in rats.
Topics: Animals; Dipyrone; Hyperalgesia; Male; Methyl Ethers; Nociception; Pain Threshold; Prospective Studi | 2017 |
Effects of sevoflurane on carrageenan- and fentanyl-induced pain hypersensitivity in Sprague-Dawley rats.
Topics: Analgesics, Opioid; Anesthetics, Inhalation; Animals; Carrageenan; Disease Models, Animal; Dose-Resp | 2009 |
The effects of gabapentin on acute opioid tolerance to remifentanil under sevoflurane anesthesia in rats.
Topics: Adjuvants, Anesthesia; Amines; Analgesics, Opioid; Anesthesia, General; Anesthetics, Inhalation; Ani | 2012 |
Questioning the cardiocirculatory excitatory effects of opioids under volatile anaesthesia.
Topics: Analgesics, Opioid; Anesthetics, Inhalation; Animals; Drug Interactions; Excitatory Amino Acid Antag | 2004 |
Effects of nitrous oxide on the rat heart in vivo: another inhalational anesthetic that preconditions the heart?
Topics: Amygdala; Anesthetics, Inhalation; Animals; Avoidance Learning; Desflurane; Excitatory Amino Acid Ag | 2005 |
Memory enhancing effect of low-dose sevoflurane does not occur in basolateral amygdala-lesioned rats.
Topics: Amygdala; Anesthetics, Inhalation; Animals; Avoidance Learning; Desflurane; Excitatory Amino Acid Ag | 2005 |