Page last updated: 2024-11-04

sevoflurane and Acute Respiratory Distress Syndrome

sevoflurane has been researched along with Acute Respiratory Distress Syndrome in 16 studies

Sevoflurane: A non-explosive inhalation anesthetic used in the induction and maintenance of general anesthesia. It does not cause respiratory irritation and may also prevent PLATELET AGGREGATION.
sevoflurane : An ether compound having fluoromethyl and 1,1,1,3,3,3-hexafluoroisopropyl as the two alkyl groups.

Research Excerpts

ExcerptRelevanceReference
"Compared with isoflurane, sevoflurane did not affect lung inflammation in ARDSexp, but it did reduce lung inflammation in ARDSp."7.85Sevoflurane, Compared With Isoflurane, Minimizes Lung Damage in Pulmonary but Not in Extrapulmonary Acute Respiratory Distress Syndrome in Rats. ( Araújo, MN; Cavalcanti, VCM; Cruz, FF; Felix, NS; Fernandes, FC; Heil, LBB; Morales, MM; Pelosi, P; Rocco, PRM; Samary, CS; Santos, CL; Silva, JD; Silva, PL; Villela, NR, 2017)
"The goal of this study was to confirm whether or not sevoflurane is more effective than propofol in ameliorating the inflammatory response in an animal model of acute respiratory distress syndrome."7.79Sevoflurane, but not propofol, reduces the lung inflammatory response and improves oxygenation in an acute respiratory distress syndrome model: a randomised laboratory study. ( Aguilar, G; Belda, FJ; Ferrando, C; Moreno, J; Piqueras, L; Soro, M, 2013)
"Sevoflurane has a stimulating effect on ENaC and Na(+) /K(+) -ATPase in vitro in LPS-injured AECII."5.38Sevoflurane reduces severity of acute lung injury possibly by impairing formation of alveolar oedema. ( Beck-Schimmer, B; Booy, C; Lachmann, RA; Leutert, AC; Schläpfer, M; Voigtsberger, S, 2012)
"Compared with isoflurane, sevoflurane did not affect lung inflammation in ARDSexp, but it did reduce lung inflammation in ARDSp."3.85Sevoflurane, Compared With Isoflurane, Minimizes Lung Damage in Pulmonary but Not in Extrapulmonary Acute Respiratory Distress Syndrome in Rats. ( Araújo, MN; Cavalcanti, VCM; Cruz, FF; Felix, NS; Fernandes, FC; Heil, LBB; Morales, MM; Pelosi, P; Rocco, PRM; Samary, CS; Santos, CL; Silva, JD; Silva, PL; Villela, NR, 2017)
"The goal of this study was to confirm whether or not sevoflurane is more effective than propofol in ameliorating the inflammatory response in an animal model of acute respiratory distress syndrome."3.79Sevoflurane, but not propofol, reduces the lung inflammatory response and improves oxygenation in an acute respiratory distress syndrome model: a randomised laboratory study. ( Aguilar, G; Belda, FJ; Ferrando, C; Moreno, J; Piqueras, L; Soro, M, 2013)
"An 82-year-old woman with amyotrophic lateral sclerosis (ALS) with bulbar paralysis, respiratory muscle paralysis, and arteriosclerosis obliterans (ASO) of the lower extremities, underwent uneventful general anesthesia with remifentanil and sevoflurane for bilateral below-knee amputation."3.74[Anesthetic management of an ALS patient with remifentanil]. ( Tagami, N; Umegaki, H, 2008)
"We conclude that the severity of remote lung injury was not different between sevoflurane and propofol anaesthesia in this porcine model of severe lower-body ischaemia and reperfusion injury."3.74Lung injury following thoracic aortic occlusion: comparison of sevoflurane and propofol anaesthesia. ( Annecke, T; Bittmann, I; Conzen, PF; Hilberath, JM; Kahr, S; Kemming, GI; Krombach, F; Kubitz, JC; Langer, K; Rehm, M, 2008)
"Sevoflurane has a stimulating effect on ENaC and Na(+) /K(+) -ATPase in vitro in LPS-injured AECII."1.38Sevoflurane reduces severity of acute lung injury possibly by impairing formation of alveolar oedema. ( Beck-Schimmer, B; Booy, C; Lachmann, RA; Leutert, AC; Schläpfer, M; Voigtsberger, S, 2012)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (25.00)29.6817
2010's6 (37.50)24.3611
2020's6 (37.50)2.80

Authors

AuthorsStudies
Reins, J1
Balling, F1
Baader, C1
Böck, E1
Schöniger, W1
van Erp, R1
Eff, S1
Hafner, S1
Orser, BA1
Wang, DS1
Lu, WY1
Nieuwenhuijs-Moeke, GJ1
Jainandunsing, JS1
Struys, MMRF1
Jerath, A1
Ferguson, ND1
Cuthbertson, B1
Liang, Z1
Zhou, H1
Tang, R1
Zhang, S1
Chen, X1
Pei, L1
Qiu, Y1
Zhang, R1
Riché, A1
Adam, N1
Monsel, A1
Xia, J1
Langeron, O1
Rouby, JJ1
Blondonnet, R1
Godet, T1
Futier, E1
Bazin, JE1
Constantin, JM1
Jabaudon, M1
Ferrando, C1
Aguilar, G1
Piqueras, L1
Soro, M1
Moreno, J1
Belda, FJ1
Araújo, MN1
Santos, CL1
Samary, CS1
Heil, LBB1
Cavalcanti, VCM1
Cruz, FF1
Felix, NS1
Silva, JD1
Morales, MM1
Pelosi, P1
Fernandes, FC1
Villela, NR1
Silva, PL1
Rocco, PRM1
Umegaki, H1
Tagami, N1
Schläpfer, M1
Leutert, AC1
Voigtsberger, S1
Lachmann, RA1
Booy, C1
Beck-Schimmer, B1
Fuzaylov, G1
Cauley, BD1
Fatheree, RS1
Leighton, BL1
Sun, YH1
Zhang, Q1
Wang, JK1
Cui, Y1
Annecke, T1
Kubitz, JC1
Langer, K1
Hilberath, JM1
Kahr, S1
Krombach, F1
Bittmann, I1
Rehm, M1
Kemming, GI1
Conzen, PF1

Clinical Trials (5)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
AnaConDa-therapy in COVID-19 Patients[NCT05586126]42 participants (Actual)Observational2020-10-01Terminated (stopped due to Concerns about possible association between drug and increased ICU mortality)
A Phase 3, Multicenter, Randomized, Controlled, Open Label, Assessor-Blinded Study to Evaluate the Efficacy and Safety of Inhaled Isoflurane Delivered Via the Sedaconda ACD-S Compared to Intravenous Propofol for Sedation of Mechanically Ventilated Intensi[NCT05327296]Phase 3235 participants (Anticipated)Interventional2022-06-30Recruiting
A Phase 3, Multicenter, Randomized, Controlled, Open Label, Assessor-Blinded Study to Evaluate the Efficacy and Safety of Inhaled Isoflurane Delivered Via the Sedaconda ACD-S Compared to Intravenous Propofol for Sedation of Mechanically Ventilated Intensi[NCT05312385]Phase 3235 participants (Anticipated)Interventional2022-04-28Recruiting
Volatile Anesthetic Pharmacokinetics During Extracorporeal Membrane[NCT05680545]10 participants (Anticipated)Interventional2024-07-01Not yet recruiting
A Randomized Pilot Clinical Trial of the Effects in Oxygenation and Hypoxic Pulmonary Vasoconstriction of Sevoflurane in Patient's Whit ARDS Secondary to Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV2)[NCT04998253]Early Phase 124 participants (Actual)Interventional2020-10-01Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for sevoflurane and Acute Respiratory Distress Syndrome

ArticleYear
Inhalational volatile-based sedation for COVID-19 pneumonia and ARDS.
    Intensive care medicine, 2020, Volume: 46, Issue:8

    Topics: Algorithms; Anesthetics, Inhalation; Anesthetics, Intravenous; Betacoronavirus; Coronavirus Infectio

2020
Inhalational volatile-based sedation for COVID-19 pneumonia and ARDS.
    Intensive care medicine, 2020, Volume: 46, Issue:8

    Topics: Algorithms; Anesthetics, Inhalation; Anesthetics, Intravenous; Betacoronavirus; Coronavirus Infectio

2020
Inhalational volatile-based sedation for COVID-19 pneumonia and ARDS.
    Intensive care medicine, 2020, Volume: 46, Issue:8

    Topics: Algorithms; Anesthetics, Inhalation; Anesthetics, Intravenous; Betacoronavirus; Coronavirus Infectio

2020
Inhalational volatile-based sedation for COVID-19 pneumonia and ARDS.
    Intensive care medicine, 2020, Volume: 46, Issue:8

    Topics: Algorithms; Anesthetics, Inhalation; Anesthetics, Intravenous; Betacoronavirus; Coronavirus Infectio

2020
Inhalational volatile-based sedation for COVID-19 pneumonia and ARDS.
    Intensive care medicine, 2020, Volume: 46, Issue:8

    Topics: Algorithms; Anesthetics, Inhalation; Anesthetics, Intravenous; Betacoronavirus; Coronavirus Infectio

2020
Inhalational volatile-based sedation for COVID-19 pneumonia and ARDS.
    Intensive care medicine, 2020, Volume: 46, Issue:8

    Topics: Algorithms; Anesthetics, Inhalation; Anesthetics, Intravenous; Betacoronavirus; Coronavirus Infectio

2020
Inhalational volatile-based sedation for COVID-19 pneumonia and ARDS.
    Intensive care medicine, 2020, Volume: 46, Issue:8

    Topics: Algorithms; Anesthetics, Inhalation; Anesthetics, Intravenous; Betacoronavirus; Coronavirus Infectio

2020
Inhalational volatile-based sedation for COVID-19 pneumonia and ARDS.
    Intensive care medicine, 2020, Volume: 46, Issue:8

    Topics: Algorithms; Anesthetics, Inhalation; Anesthetics, Intravenous; Betacoronavirus; Coronavirus Infectio

2020
Inhalational volatile-based sedation for COVID-19 pneumonia and ARDS.
    Intensive care medicine, 2020, Volume: 46, Issue:8

    Topics: Algorithms; Anesthetics, Inhalation; Anesthetics, Intravenous; Betacoronavirus; Coronavirus Infectio

2020

Other Studies

15 other studies available for sevoflurane and Acute Respiratory Distress Syndrome

ArticleYear
[Nephrogenic diabetes insipidus after inhalation sedation with sevoflurane in a patient with COVID-19-associated acute respiratory distress syndrome].
    Die Anaesthesiologie, 2023, Volume: 72, Issue:11

    Topics: Anesthetics, Inhalation; COVID-19; Diabetes Insipidus, Nephrogenic; Diabetes Mellitus; Humans; Pneum

2023
Sedating ventilated COVID-19 patients with inhalational anesthetic drugs.
    EBioMedicine, 2020, Volume: 55

    Topics: Betacoronavirus; Coronavirus Infections; COVID-19; Humans; Pandemics; Pilot Projects; Pneumonia, Vir

2020
Sevoflurane, a sigh of relief in COVID-19?
    British journal of anaesthesia, 2020, Volume: 125, Issue:2

    Topics: Anesthetics, Inhalation; Conscious Sedation; Coronavirus Infections; COVID-19; Humans; Pandemics; Pn

2020
Autologous transplantation of adipose-derived stromal cells combined with sevoflurane ameliorates acute lung injury induced by cecal ligation and puncture in rats.
    Scientific reports, 2020, 08-13, Volume: 10, Issue:1

    Topics: Acute Lung Injury; Adipose Tissue; Animals; Bronchoalveolar Lavage Fluid; Cecum; Cell- and Tissue-Ba

2020
Perioperative respiratory distress in a child due to plastic bronchitis triggered by allergic reaction to sevoflurane.
    BMJ case reports, 2020, Sep-18, Volume: 13, Issue:9

    Topics: Airway Obstruction; Anesthetics, Inhalation; Bronchitis; Bronchodilator Agents; Child, Preschool; Dr

2020
Sevoflurane in Acute Respiratory Distress Syndrome: Are Lung Protection and Anesthesia Depth Influenced by Pulmonary Morphology?
    American journal of respiratory and critical care medicine, 2018, 03-15, Volume: 197, Issue:6

    Topics: Anesthesia; Humans; Lung; Pilot Projects; Respiratory Distress Syndrome; Sevoflurane

2018
Reply to Riché et al.: Sevoflurane in Acute Respiratory Distress Syndrome: Are Lung Protection and Anesthesia Depth Influenced by Pulmonary Morphology?
    American journal of respiratory and critical care medicine, 2018, 03-15, Volume: 197, Issue:6

    Topics: Anesthesia; Humans; Lung; Pilot Projects; Respiratory Distress Syndrome; Sevoflurane

2018
Sevoflurane, but not propofol, reduces the lung inflammatory response and improves oxygenation in an acute respiratory distress syndrome model: a randomised laboratory study.
    European journal of anaesthesiology, 2013, Volume: 30, Issue:8

    Topics: Anesthesia; Anesthetics, Inhalation; Animals; Cell Membrane Permeability; Disease Models, Animal; He

2013
Sevoflurane, but not propofol, reduces the lung inflammatory response and improves oxygenation in an acute respiratory distress syndrome model: a randomised laboratory study.
    European journal of anaesthesiology, 2013, Volume: 30, Issue:8

    Topics: Anesthesia; Anesthetics, Inhalation; Animals; Cell Membrane Permeability; Disease Models, Animal; He

2013
Sevoflurane, but not propofol, reduces the lung inflammatory response and improves oxygenation in an acute respiratory distress syndrome model: a randomised laboratory study.
    European journal of anaesthesiology, 2013, Volume: 30, Issue:8

    Topics: Anesthesia; Anesthetics, Inhalation; Animals; Cell Membrane Permeability; Disease Models, Animal; He

2013
Sevoflurane, but not propofol, reduces the lung inflammatory response and improves oxygenation in an acute respiratory distress syndrome model: a randomised laboratory study.
    European journal of anaesthesiology, 2013, Volume: 30, Issue:8

    Topics: Anesthesia; Anesthetics, Inhalation; Animals; Cell Membrane Permeability; Disease Models, Animal; He

2013
Sevoflurane, but not propofol, reduces the lung inflammatory response and improves oxygenation in an acute respiratory distress syndrome model: a randomised laboratory study.
    European journal of anaesthesiology, 2013, Volume: 30, Issue:8

    Topics: Anesthesia; Anesthetics, Inhalation; Animals; Cell Membrane Permeability; Disease Models, Animal; He

2013
Sevoflurane, but not propofol, reduces the lung inflammatory response and improves oxygenation in an acute respiratory distress syndrome model: a randomised laboratory study.
    European journal of anaesthesiology, 2013, Volume: 30, Issue:8

    Topics: Anesthesia; Anesthetics, Inhalation; Animals; Cell Membrane Permeability; Disease Models, Animal; He

2013
Sevoflurane, but not propofol, reduces the lung inflammatory response and improves oxygenation in an acute respiratory distress syndrome model: a randomised laboratory study.
    European journal of anaesthesiology, 2013, Volume: 30, Issue:8

    Topics: Anesthesia; Anesthetics, Inhalation; Animals; Cell Membrane Permeability; Disease Models, Animal; He

2013
Sevoflurane, but not propofol, reduces the lung inflammatory response and improves oxygenation in an acute respiratory distress syndrome model: a randomised laboratory study.
    European journal of anaesthesiology, 2013, Volume: 30, Issue:8

    Topics: Anesthesia; Anesthetics, Inhalation; Animals; Cell Membrane Permeability; Disease Models, Animal; He

2013
Sevoflurane, but not propofol, reduces the lung inflammatory response and improves oxygenation in an acute respiratory distress syndrome model: a randomised laboratory study.
    European journal of anaesthesiology, 2013, Volume: 30, Issue:8

    Topics: Anesthesia; Anesthetics, Inhalation; Animals; Cell Membrane Permeability; Disease Models, Animal; He

2013
Sevoflurane, Compared With Isoflurane, Minimizes Lung Damage in Pulmonary but Not in Extrapulmonary Acute Respiratory Distress Syndrome in Rats.
    Anesthesia and analgesia, 2017, Volume: 125, Issue:2

    Topics: A549 Cells; Anesthetics; Animals; Escherichia coli; Female; Humans; Inflammation; Interleukin-6; Iso

2017
[Anesthetic management of an ALS patient with remifentanil].
    Masui. The Japanese journal of anesthesiology, 2008, Volume: 57, Issue:9

    Topics: Aged, 80 and over; Amputation, Surgical; Amyotrophic Lateral Sclerosis; Anesthesia, General; Arterio

2008
Sevoflurane reduces severity of acute lung injury possibly by impairing formation of alveolar oedema.
    Clinical and experimental immunology, 2012, Volume: 168, Issue:1

    Topics: Acute Lung Injury; Anesthetics; Animals; Biological Transport, Active; Cell Line; Cell Survival; Lip

2012
Spontaneous ventilation via facemask and laryngeal mask airway as bridge to extracorporeal membrane oxygenation during long-segment tracheal stenosis repair.
    Paediatric anaesthesia, 2012, Volume: 22, Issue:12

    Topics: Airway Management; Anesthesia, General; Anesthetics, Inhalation; Bronchoscopy; Carbon Dioxide; Extra

2012
Acute respiratory distress syndrome after an exothermic Baralyme-sevoflurane reaction.
    Anesthesiology, 2004, Volume: 101, Issue:2

    Topics: Absorption; Adult; Anesthetics, Inhalation; Barium Compounds; Calcium Hydroxide; Carbon Dioxide; Car

2004
[Effects of sevoflurane on membrane permeability of alveolar capillaries in rats with acute lung injury caused by endotoxin].
    Zhonghua wai ke za zhi [Chinese journal of surgery], 2004, Aug-22, Volume: 42, Issue:16

    Topics: Animals; Blood-Air Barrier; Bronchoalveolar Lavage Fluid; Capillary Permeability; Endotoxins; Female

2004
Lung injury following thoracic aortic occlusion: comparison of sevoflurane and propofol anaesthesia.
    Acta anaesthesiologica Scandinavica, 2008, Volume: 52, Issue:7

    Topics: Anesthesia; Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Aorta, Thoracic; Arterial Oc

2008