Page last updated: 2024-11-04

sevoflurane and Acute Kidney Failure

sevoflurane has been researched along with Acute Kidney Failure in 16 studies

Sevoflurane: A non-explosive inhalation anesthetic used in the induction and maintenance of general anesthesia. It does not cause respiratory irritation and may also prevent PLATELET AGGREGATION.
sevoflurane : An ether compound having fluoromethyl and 1,1,1,3,3,3-hexafluoroisopropyl as the two alkyl groups.

Research Excerpts

ExcerptRelevanceReference
"Propofol may help to protect against ischaemic acute kidney injury (AKI); however, research on this topic is sparse."7.91Effect of sevoflurane-based or propofol-based anaesthesia on the incidence of postoperative acute kidney injury: A retrospective propensity score-matched analysis. ( Han, S; Jheon, S; Ji, E; Kim, J; Kim, K; Oh, TK, 2019)
"To investigate the influence of intravenous nonselective cyclooxygenase inhibitor, ketoprofen (keto), on kidney histological changes and kidney cytokines, tumor necrosis factor-α (TNF-α) and interleukin-1 (IL-1), levels after hemorrhage of 30% of volemia (three times 10%, intervals of 10 min) in rats."7.78Renal histology and immunohistochemistry after acute hemorrhage in rats under sevoflurane and ketoprofen effect. ( Amorim, RL; Castiglia, YM; Cruz, DS; Guedes, FS; Rodrigues, MM; Silva, LM; Vianna, PT, 2012)
"Sevoflurane pretreatment were performed on WT and HIF-2α knockout mice before renal ischemia/reperfusion."5.42Sevoflurane pretreatment enhance HIF-2α expression in mice after renal ischemia/reperfusion injury. ( Chen, J; He, Z; Xu, H; Zhan, Q; Zheng, B, 2015)
"Sevoflurane pretreatment comprised exposure to 2."5.39Effects of sevoflurane pretreatment on renal Src and FAK expression in diabetic rats after renal ischemia/reperfusion injury. ( Liao, WT; Sun, L; Yang, LK; Zhou, SP, 2013)
"Sevoflurane has anti-inflammation properties, and renal ischemia/reperfusion under sevoflurane anesthesia resulted in drastic improvements in renal function."5.36Sevoflurane protects against acute kidney injury in a small-size liver transplantation model. ( He, Y; Kong, HY; Wang, LQ; Xie, HY; Zheng, SS; Zhu, SM, 2010)
"The anesthetic sevoflurane (SEV) has been shown to protect against organ's injury during sepsis."4.12Sevoflurane ameliorates LPS-induced inflammatory injury of HK-2 cells through Sirtuin1/NF-κB pathway. ( Miaomiao, Y; Peipei, W; Ping, W; Shuo, W, 2022)
"Propofol may help to protect against ischaemic acute kidney injury (AKI); however, research on this topic is sparse."3.91Effect of sevoflurane-based or propofol-based anaesthesia on the incidence of postoperative acute kidney injury: A retrospective propensity score-matched analysis. ( Han, S; Jheon, S; Ji, E; Kim, J; Kim, K; Oh, TK, 2019)
"To investigate the influence of intravenous nonselective cyclooxygenase inhibitor, ketoprofen (keto), on kidney histological changes and kidney cytokines, tumor necrosis factor-α (TNF-α) and interleukin-1 (IL-1), levels after hemorrhage of 30% of volemia (three times 10%, intervals of 10 min) in rats."3.78Renal histology and immunohistochemistry after acute hemorrhage in rats under sevoflurane and ketoprofen effect. ( Amorim, RL; Castiglia, YM; Cruz, DS; Guedes, FS; Rodrigues, MM; Silva, LM; Vianna, PT, 2012)
"Propofol has been shown to provide protection against renal ischemia/reperfusion injury experimentally, but clinical evidence is lacking."2.79Anesthetics influence the incidence of acute kidney injury following valvular heart surgery. ( Kwak, YL; Shim, JK; Song, Y; Yang, SY; Yoo, YC, 2014)
"The sevoflurane was administered with an expired fraction target of 2% during short-term procedural sedation."1.48Sevoflurane for procedural sedation in critically ill patients: A pharmacokinetic comparative study between burn and non-burn patients. ( Bazin, JE; Biboulet, C; Bourdeaux, D; Constantin, JM; Houze, P; Launay, JM; Legrand, M; Lenoire, A; Mebazaa, A; Perbet, S; Pereira, B; Plaud, B; Sadoune, M; Sautou, V, 2018)
"Sevoflurane pretreatment were performed on WT and HIF-2α knockout mice before renal ischemia/reperfusion."1.42Sevoflurane pretreatment enhance HIF-2α expression in mice after renal ischemia/reperfusion injury. ( Chen, J; He, Z; Xu, H; Zhan, Q; Zheng, B, 2015)
"Sevoflurane pretreatment comprised exposure to 2."1.39Effects of sevoflurane pretreatment on renal Src and FAK expression in diabetic rats after renal ischemia/reperfusion injury. ( Liao, WT; Sun, L; Yang, LK; Zhou, SP, 2013)
"The incidence of acute renal failure, initial dysfunction of the graft, reperfusion syndrome, rejection, and the transaminase peak depending value depending on the hypnotic used, were recorded."1.38[Retrospective comparative study between sevoflurane and propofol in maintaining anaesthesia during liver transplant: Effects on kidney and liver function]. ( Alonso Menárguez, B; Arribas Pérez, P; Gajate Martín, L; García Fernández, J; García Suárez, J; Martín Martín, A; Moreno Ballesteros, R, 2012)
"Sevoflurane has anti-inflammation properties, and renal ischemia/reperfusion under sevoflurane anesthesia resulted in drastic improvements in renal function."1.36Sevoflurane protects against acute kidney injury in a small-size liver transplantation model. ( He, Y; Kong, HY; Wang, LQ; Xie, HY; Zheng, SS; Zhu, SM, 2010)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (6.25)18.2507
2000's0 (0.00)29.6817
2010's12 (75.00)24.3611
2020's3 (18.75)2.80

Authors

AuthorsStudies
Park, M1
Jung, K1
Cho, HS1
Min, JJ1
Peipei, W1
Ping, W1
Miaomiao, Y1
Shuo, W1
Zeng, B1
Liu, Y1
Xu, J1
Niu, L1
Wu, Y1
Zhang, D1
Tang, X1
Zhu, Z1
Chen, Y1
Hu, L1
Yu, S1
Yu, P1
Zhang, J1
Wang, W1
Nieuwenhuijs-Moeke, GJ1
Nieuwenhuijs, VB1
Seelen, MAJ1
Berger, SP1
van den Heuvel, MC1
Burgerhof, JGM1
Ottens, PJ1
Ploeg, RJ1
Leuvenink, HGD1
Struys, MMRF1
Ozturk, O1
Ustebay, S1
Eroglu, HA1
Günay, M1
Adali, Y1
Donmez, İ1
Erbas, M1
Perbet, S1
Bourdeaux, D1
Lenoire, A1
Biboulet, C1
Pereira, B1
Sadoune, M1
Plaud, B1
Launay, JM1
Bazin, JE1
Sautou, V1
Mebazaa, A1
Houze, P1
Constantin, JM1
Legrand, M1
Oh, TK1
Kim, J1
Han, S1
Kim, K1
Jheon, S1
Ji, E1
Zhou, SP1
Liao, WT1
Yang, LK1
Sun, L1
Yoo, YC1
Shim, JK1
Song, Y1
Yang, SY1
Kwak, YL1
Fernandes, A1
Ettinger, J1
Amaral, F1
Ramalho, MJ1
Alves, R1
Módolo, NS1
Zheng, B1
Zhan, Q1
Chen, J1
Xu, H1
He, Z1
Bang, JY1
Lee, J1
Oh, J1
Song, JG1
Hwang, GS1
Kong, HY1
Zhu, SM1
Wang, LQ1
He, Y1
Xie, HY1
Zheng, SS1
Guedes, FS1
Cruz, DS1
Rodrigues, MM1
Silva, LM1
Amorim, RL1
Vianna, PT1
Castiglia, YM1
Alonso Menárguez, B1
Gajate Martín, L1
García Suárez, J1
Martín Martín, A1
Moreno Ballesteros, R1
Arribas Pérez, P1
García Fernández, J1
Tung, A1
Jacobsohn, E1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
"Volatile Anesthetic Protection Of Renal Transplants: VAPOR-1-trail"[NCT01248871]120 participants (Actual)Interventional2010-09-30Completed
A Pharmacokinetic Study of Sevoflurane Inhalation in Burn ICU Patients[NCT02048683]Phase 224 participants (Actual)Interventional2013-12-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for sevoflurane and Acute Kidney Failure

ArticleYear
Future Directions in Optimizing Anesthesia to Reduce Perioperative Acute Kidney Injury.
    American journal of nephrology, 2023, Volume: 54, Issue:9-10

    Topics: Acute Kidney Injury; Anesthesia; Anesthetics; Humans; Propofol; Sevoflurane

2023

Trials

3 trials available for sevoflurane and Acute Kidney Failure

ArticleYear
Propofol-based anaesthesia versus sevoflurane-based anaesthesia for living donor kidney transplantation: results of the VAPOR-1 randomized controlled trial.
    British journal of anaesthesia, 2017, May-01, Volume: 118, Issue:5

    Topics: Acute Kidney Injury; Adolescent; Adult; Aged; Anesthesia, Inhalation; Anesthesia, Intravenous; Anest

2017
Anesthetics influence the incidence of acute kidney injury following valvular heart surgery.
    Kidney international, 2014, Volume: 86, Issue:2

    Topics: Acute Kidney Injury; Aged; Anesthetics, General; Anesthetics, Inhalation; Anesthetics, Intravenous;

2014
General anesthesia type does not influence serum levels of neutrophil gelatinase-associated lipocalin during the perioperative period in video laparoscopic bariatric surgery.
    Clinics (Sao Paulo, Brazil), 2014, Volume: 69, Issue:10

    Topics: Acute Kidney Injury; Acute-Phase Proteins; Adult; Anesthesia, General; Anesthesia, Intravenous; Anes

2014

Other Studies

12 other studies available for sevoflurane and Acute Kidney Failure

ArticleYear
Renal injury from sevoflurane in noncardiac surgery: a retrospective cohort study.
    British journal of anaesthesia, 2022, Volume: 129, Issue:2

    Topics: Acute Kidney Injury; Anesthetics, Inhalation; Cohort Studies; Humans; Kidney; Methyl Ethers; Retrosp

2022
Sevoflurane ameliorates LPS-induced inflammatory injury of HK-2 cells through Sirtuin1/NF-κB pathway.
    Allergologia et immunopathologia, 2022, Volume: 50, Issue:4

    Topics: Acute Kidney Injury; Epithelial Cells; Humans; Inflammation; Lipopolysaccharides; NF-kappa B; Sepsis

2022
An experimental study of ascorbic acid effects in acute renal failure under general anesthesia.
    Acta cirurgica brasileira, 2017, Volume: 32, Issue:10

    Topics: Acute Kidney Injury; Anesthesia, General; Anesthetics, Inhalation; Animals; Ascorbic Acid; Biomarker

2017
Sevoflurane for procedural sedation in critically ill patients: A pharmacokinetic comparative study between burn and non-burn patients.
    Anaesthesia, critical care & pain medicine, 2018, Volume: 37, Issue:6

    Topics: Acute Kidney Injury; Adult; Aged; Aged, 80 and over; Anesthetics, Inhalation; Burns; Conscious Sedat

2018
Effect of sevoflurane-based or propofol-based anaesthesia on the incidence of postoperative acute kidney injury: A retrospective propensity score-matched analysis.
    European journal of anaesthesiology, 2019, Volume: 36, Issue:9

    Topics: Acute Kidney Injury; Aged; Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intravenous; C

2019
Effects of sevoflurane pretreatment on renal Src and FAK expression in diabetic rats after renal ischemia/reperfusion injury.
    Molecular and cellular biochemistry, 2013, Volume: 384, Issue:1-2

    Topics: Acute Kidney Injury; Animals; Apoptosis; Blood Urea Nitrogen; Creatinine; Diabetes Mellitus, Experim

2013
Sevoflurane pretreatment enhance HIF-2α expression in mice after renal ischemia/reperfusion injury.
    International journal of clinical and experimental pathology, 2015, Volume: 8, Issue:10

    Topics: Acute Kidney Injury; Animals; Anti-Inflammatory Agents; Basic Helix-Loop-Helix Transcription Factors

2015
The Influence of Propofol and Sevoflurane on Acute Kidney Injury After Colorectal Surgery: A Retrospective Cohort Study.
    Anesthesia and analgesia, 2016, Volume: 123, Issue:2

    Topics: Acute Kidney Injury; Aged; Anesthetics, Inhalation; Anesthetics, Intravenous; Chi-Square Distributio

2016
Sevoflurane protects against acute kidney injury in a small-size liver transplantation model.
    American journal of nephrology, 2010, Volume: 32, Issue:4

    Topics: Acute Kidney Injury; Acute-Phase Proteins; Anesthetics, Inhalation; Animals; Creatinine; Fluorides;

2010
Renal histology and immunohistochemistry after acute hemorrhage in rats under sevoflurane and ketoprofen effect.
    Acta cirurgica brasileira, 2012, Volume: 27, Issue:1

    Topics: Acute Disease; Acute Kidney Injury; Anesthetics, Inhalation; Animals; Anti-Inflammatory Agents, Non-

2012
[Retrospective comparative study between sevoflurane and propofol in maintaining anaesthesia during liver transplant: Effects on kidney and liver function].
    Revista espanola de anestesiologia y reanimacion, 2012, Volume: 59, Issue:5

    Topics: Acute Kidney Injury; Anesthesia; Anesthetics, Inhalation; Anesthetics, Intravenous; Female; Humans;

2012
A case of nonoliguric renal failure after general anesthesia with sevoflurane and desflurane.
    Anesthesia and analgesia, 1997, Volume: 85, Issue:6

    Topics: Acute Kidney Injury; Adult; Anesthesia, General; Anesthetics, Inhalation; Desflurane; Ethers; Humans

1997