sevoflurane has been researched along with Acute Confusional Senile Dementia in 17 studies
Sevoflurane: A non-explosive inhalation anesthetic used in the induction and maintenance of general anesthesia. It does not cause respiratory irritation and may also prevent PLATELET AGGREGATION.
sevoflurane : An ether compound having fluoromethyl and 1,1,1,3,3,3-hexafluoroisopropyl as the two alkyl groups.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Sevoflurane anesthesia enhanced ApoE mRNA, total ApoE, full-length ApoE, ApoE fragments, Tau phosphorylation (AT8 and PHF1), and cognitive impairment in young mice, but not in adult mice." | 8.12 | Effects of toxic apolipoprotein E fragments on Tau phosphorylation and cognitive impairment in neonatal mice under sevoflurane anesthesia. ( Pan, J; Yang, M; Yu, Y; Zhao, Y; Zhuang, X, 2022) |
| "We aimed to investigate the effects of recurrent sevoflurane anesthesia on cognitive functions in Alzheimer Disease." | 7.91 | Effects of recurrent sevoflurane anesthesia on cognitive functions with streptozotocin induced Alzheimer disease. ( Arslan, M; Dogan, HT; Erkent, FD; Guney, S; Isik, B; Kucuk, A; Neselioglu, S; Ozturk, L, 2019) |
| " Therefore, the authors set out to assess the effects of sevoflurane, the most commonly used inhalation anesthetic, on caspase activation, apoptosis, beta-amyloid protein levels, and neuroinflammation in the brain tissues of neonatal naïve and Alzheimer disease (AD) transgenic mice." | 7.76 | Anesthetic sevoflurane causes neurotoxicity differently in neonatal naïve and Alzheimer disease transgenic mice. ( Dong, Y; Lu, Y; Wu, X; Xie, Z; Xu, Z; Zhang, Y, 2010) |
| "Sevoflurane anesthesia enhanced ApoE mRNA, total ApoE, full-length ApoE, ApoE fragments, Tau phosphorylation (AT8 and PHF1), and cognitive impairment in young mice, but not in adult mice." | 4.12 | Effects of toxic apolipoprotein E fragments on Tau phosphorylation and cognitive impairment in neonatal mice under sevoflurane anesthesia. ( Pan, J; Yang, M; Yu, Y; Zhao, Y; Zhuang, X, 2022) |
| "We aimed to investigate the effects of recurrent sevoflurane anesthesia on cognitive functions in Alzheimer Disease." | 3.91 | Effects of recurrent sevoflurane anesthesia on cognitive functions with streptozotocin induced Alzheimer disease. ( Arslan, M; Dogan, HT; Erkent, FD; Guney, S; Isik, B; Kucuk, A; Neselioglu, S; Ozturk, L, 2019) |
| " Therefore, the authors set out to assess the effects of sevoflurane, the most commonly used inhalation anesthetic, on caspase activation, apoptosis, beta-amyloid protein levels, and neuroinflammation in the brain tissues of neonatal naïve and Alzheimer disease (AD) transgenic mice." | 3.76 | Anesthetic sevoflurane causes neurotoxicity differently in neonatal naïve and Alzheimer disease transgenic mice. ( Dong, Y; Lu, Y; Wu, X; Xie, Z; Xu, Z; Zhang, Y, 2010) |
| "These results suggest that inhalational anesthetic sevoflurane may promote Alzheimer disease neuropathogenesis." | 3.75 | The common inhalational anesthetic sevoflurane induces apoptosis and increases beta-amyloid protein levels. ( Crosby, G; Culley, DJ; Dong, Y; Marcantonio, ER; Moir, RD; Tanzi, RE; Xia, W; Xie, Z; Zhang, B; Zhang, G, 2009) |
| "The incidence of Alzheimer's disease (AD) in individuals >65 years of age is 13% and ~66 million individuals in this age group undergo surgery annually under anesthesia." | 2.52 | Effect of the inhaled anesthetics isoflurane, sevoflurane and desflurane on the neuropathogenesis of Alzheimer's disease (review). ( Jiang, H; Jiang, J, 2015) |
| "Sevoflurane is a general anesthetic agent which is commonly used in clinical practice." | 1.72 | Sevoflurane Induces Neurotoxicity in the Animal Model with Alzheimer's Disease Neuropathology via Modulating Glutamate Transporter and Neuronal Apoptosis. ( Chang, RCC; Chu, JMT; Huang, C; Kwong, VSW; Liu, Y; Wong, GTC, 2022) |
| "Accumulation and spread of tau in Alzheimer's disease and other tauopathies occur in a prion-like manner." | 1.62 | The anesthetic sevoflurane induces tau trafficking from neurons to microglia. ( Dong, Y; Fang, F; Huang, L; Liang, F; Quan, Q; Tanzi, RE; Xie, Z; Yang, G; Zhang, Y, 2021) |
| "Sevoflurane is a common anesthetic widely used in clinical practice." | 1.51 | Transcriptomic analysis reveals the molecular mechanism of Alzheimer-related neuropathology induced by sevoflurane in mice. ( Chang, YZ; Gao, G; Ge, X; Israr, M; Li, B; Shi, Z; Yu, P; Zhang, Y; Zuo, Y, 2019) |
| "Increasingly more aged people with Alzheimer's disease (AD) must undergo surgery with general anesthesia for various reasons." | 1.40 | Smaller sized inhaled anesthetics have more potency on senescence-accelerated prone-8 mice compared with senescence-resistant-1 mice. ( Deng, Y; He, Z; Lu, B; Qi, B; Su, D; Tian, J; Wang, X; Xu, H; Zheng, B, 2014) |
| "Patients with Alzheimer's disease (AD) exhibit a failure in the clearance of amyloid β peptides (Aβ) from the central nervous system." | 1.39 | Sevoflurane alters the expression of receptors and enzymes involved in Aβ clearance in rats. ( Gao, M; Liu, Y; Ma, L; Pan, N; Zhang, L, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (5.88) | 29.6817 |
| 2010's | 10 (58.82) | 24.3611 |
| 2020's | 6 (35.29) | 2.80 |
| Authors | Studies |
|---|---|
| Han, F | 1 |
| Zhao, J | 1 |
| Zhao, G | 1 |
| Niikura, R | 1 |
| Miyazaki, T | 1 |
| Takase, K | 1 |
| Sasaguri, H | 1 |
| Saito, T | 1 |
| Saido, TC | 1 |
| Goto, T | 1 |
| Huang, C | 1 |
| Chu, JMT | 1 |
| Liu, Y | 2 |
| Kwong, VSW | 1 |
| Chang, RCC | 1 |
| Wong, GTC | 1 |
| Yu, Y | 2 |
| Yang, M | 1 |
| Zhuang, X | 1 |
| Pan, J | 1 |
| Zhao, Y | 1 |
| Erkent, FD | 1 |
| Isik, B | 1 |
| Kucuk, A | 1 |
| Ozturk, L | 1 |
| Neselioglu, S | 1 |
| Dogan, HT | 1 |
| Guney, S | 1 |
| Arslan, M | 1 |
| Dong, Y | 3 |
| Liang, F | 1 |
| Huang, L | 1 |
| Fang, F | 1 |
| Yang, G | 1 |
| Tanzi, RE | 2 |
| Zhang, Y | 3 |
| Quan, Q | 1 |
| Xie, Z | 3 |
| Cong, L | 1 |
| Cong, Y | 1 |
| Feng, N | 1 |
| Liang, W | 1 |
| Wu, Y | 1 |
| Ge, X | 1 |
| Zuo, Y | 1 |
| Israr, M | 1 |
| Li, B | 1 |
| Yu, P | 1 |
| Gao, G | 1 |
| Chang, YZ | 1 |
| Shi, Z | 1 |
| Gao, M | 1 |
| Ma, L | 1 |
| Zhang, L | 1 |
| Pan, N | 1 |
| Chen, CW | 1 |
| Lin, WY | 1 |
| Chen, KB | 1 |
| Wu, YS | 1 |
| Kuo, YC | 1 |
| Liu, HP | 1 |
| Li, CY | 1 |
| Xu, H | 1 |
| Lu, B | 1 |
| Zheng, B | 1 |
| Tian, J | 1 |
| Qi, B | 1 |
| Deng, Y | 1 |
| He, Z | 1 |
| Su, D | 1 |
| Wang, X | 1 |
| Jiang, J | 1 |
| Jiang, H | 1 |
| Zhang, G | 1 |
| Zhang, B | 1 |
| Moir, RD | 1 |
| Xia, W | 1 |
| Marcantonio, ER | 1 |
| Culley, DJ | 1 |
| Crosby, G | 1 |
| Bianchi, SL | 1 |
| Caltagarone, BM | 1 |
| Laferla, FM | 1 |
| Eckenhoff, RG | 2 |
| Kelz, MB | 1 |
| Lu, Y | 1 |
| Wu, X | 1 |
| Xu, Z | 1 |
| Marcos Vidal, JM | 1 |
| González de Castro, R | 1 |
| Higuera Miguélez, E | 1 |
| Soria Gulina, C | 1 |
| Ye, X | 1 |
| Lian, Q | 1 |
| Eckenhoff, MF | 1 |
| Pan, JZ | 1 |
1 review available for sevoflurane and Acute Confusional Senile Dementia
| Article | Year |
|---|---|
Effect of the inhaled anesthetics isoflurane, sevoflurane and desflurane on the neuropathogenesis of Alzheimer's disease (review).
Topics: Alzheimer Disease; Amyloid beta-Peptides; Anesthetics, Inhalation; Caspases; Cognition; Desflurane; | 2015 |
16 other studies available for sevoflurane and Acute Confusional Senile Dementia
| Article | Year |
|---|---|
Prolonged Volatile Anesthetic Exposure Exacerbates Cognitive Impairment and Neuropathology in the 5xFAD Mouse Model of Alzheimer's Disease.
Topics: Alzheimer Disease; Anesthetics, Inhalation; Animals; Cognitive Dysfunction; Disease Models, Animal; | 2021 |
Assessments of prolonged effects of desflurane and sevoflurane on motor learning deficits in aged App
Topics: Aged; Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Desflurane; | 2022 |
Sevoflurane Induces Neurotoxicity in the Animal Model with Alzheimer's Disease Neuropathology via Modulating Glutamate Transporter and Neuronal Apoptosis.
Topics: Alzheimer Disease; Amino Acid Transport System X-AG; Anesthetics, Inhalation; Animals; Apoptosis; Di | 2022 |
Effects of toxic apolipoprotein E fragments on Tau phosphorylation and cognitive impairment in neonatal mice under sevoflurane anesthesia.
Topics: Alzheimer Disease; Anesthesia; Animals; Animals, Newborn; Apolipoprotein E2; Apolipoprotein E3; Apol | 2022 |
Effects of recurrent sevoflurane anesthesia on cognitive functions with streptozotocin induced Alzheimer disease.
Topics: Alzheimer Disease; Anesthesia; Anesthetics, Inhalation; Animals; Cognition; Maze Learning; Methyl Et | 2019 |
The anesthetic sevoflurane induces tau trafficking from neurons to microglia.
Topics: Alzheimer Disease; Anesthetics, Inhalation; Animals; Brain; Cognitive Dysfunction; Extracellular Ves | 2021 |
Up-regulated microRNA-132 reduces the cognition-damaging effect of sevoflurane on Alzheimer's disease rats by inhibiting FOXA1.
Topics: Alzheimer Disease; Animals; Apoptosis; Cognition; Hepatocyte Nuclear Factor 3-alpha; MicroRNAs; Rats | 2021 |
Transcriptomic analysis reveals the molecular mechanism of Alzheimer-related neuropathology induced by sevoflurane in mice.
Topics: Alzheimer Disease; Anesthetics; Animals; Cognitive Dysfunction; Computational Biology; Disease Model | 2019 |
Sevoflurane alters the expression of receptors and enzymes involved in Aβ clearance in rats.
Topics: Aging; Alzheimer Disease; Amyloid beta-Peptides; Anesthetics, Inhalation; Animals; Blood-Brain Barri | 2013 |
Inhalational anesthetic sevoflurane rescues retina function in Alzheimer's disease transgenic Drosophila.
Topics: Alzheimer Disease; Anesthetics, Inhalation; Animals; Animals, Genetically Modified; Brain; Drosophil | 2013 |
Smaller sized inhaled anesthetics have more potency on senescence-accelerated prone-8 mice compared with senescence-resistant-1 mice.
Topics: Aging; Alzheimer Disease; Analysis of Variance; Anesthetics, Inhalation; Animals; Desflurane; Diseas | 2014 |
The common inhalational anesthetic sevoflurane induces apoptosis and increases beta-amyloid protein levels.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid Precursor Protein Secretases; Anesthetics, Inhalat | 2009 |
Inhaled anesthetic potency in aged Alzheimer mice.
Topics: Alzheimer Disease; Anesthesia Recovery Period; Anesthetics, Inhalation; Animals; Dose-Response Relat | 2010 |
Anesthetic sevoflurane causes neurotoxicity differently in neonatal naïve and Alzheimer disease transgenic mice.
Topics: Alzheimer Disease; Anesthetics, Inhalation; Animals; Animals, Newborn; Apoptosis; Brain; Caspase 3; | 2010 |
[Sedation with sevoflurane in a procedure outside the operating theatre using the AnaConDa® device].
Topics: Aged, 80 and over; Alzheimer Disease; Angina Pectoris; Deep Sedation; Equipment Design; Filtration; | 2013 |
Differential general anesthetic effects on microglial cytokine expression.
Topics: Alzheimer Disease; Anesthetics; Cells, Cultured; Cytokines; Gene Expression Regulation; Humans; Infl | 2013 |