sertraline has been researched along with Disease Models, Animal in 76 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (5.26) | 18.2507 |
| 2000's | 8 (10.53) | 29.6817 |
| 2010's | 55 (72.37) | 24.3611 |
| 2020's | 9 (11.84) | 2.80 |
| Authors | Studies |
|---|---|
| Bush, LR; Campbell, UC; Engel, SR; Hardy, LW; Hewitt, MC; Koch, P; Ma, J; Malcolm, SC; Saraswat, LD; Schreiber, R; Shao, L; Spear, KL; Spicer, NA; Varney, MA; Wang, F | 1 |
| Braisted, J; Dranchak, P; Earnest, TW; Gu, X; Hoon, MA; Inglese, J; Oliphant, E; Solinski, HJ | 1 |
| Abrams, RPM; Bachani, M; Balasubramanian, A; Brimacombe, K; Dorjsuren, D; Eastman, RT; Hall, MD; Jadhav, A; Lee, MH; Li, W; Malik, N; Nath, A; Padmanabhan, R; Simeonov, A; Steiner, JP; Teramoto, T; Yasgar, A; Zakharov, AV | 1 |
| Gormus, ZIS; Gunes, CE; Koca, RO; Kutlu, S; Solak, H | 1 |
| Bali, A; Hanifa, M; Sree, AB | 1 |
| Hamdi, H | 1 |
| Bolding, IJ; Boone, DR; Cardenas, C; DeWitt, DS; Falduto, MT; Hellmich, HL; Micci, MA; Prough, DS; Sell, SL; Torres, KEO; Weisz, HA; Willey, HE | 1 |
| Akkari, L; Beijersbergen, RL; Benedict, B; Bernards, R; de Oliveira, RL; du Chatinier, A; Evers, B; Gadiot, J; Gao, D; Jin, G; Jin, H; Jochems, F; Lieftink, C; Mainardi, S; Morris, B; Qin, W; Ramirez, C; Sanchez, AM; Schepers, A; Te Riele, H; Vegna, S; Wang, C; Wang, L; Wang, W; Xue, Z | 1 |
| Hasegawa, F; Karasawa, K; Moriyama, T; Nitta, K; Uchida, K | 1 |
| Ding, ZC; Fang, XX; Guo, Y; Jiang, XY; Li, YF; Ran, YH; Shang, C; Sun, LJ; Wang, HL; Yao, JQ; Zhang, LM | 1 |
| Barbosa, LRS; Cunha-Junior, E; da Costa-Silva, TA; Dias Ferreira, D; Galisteo, AJ; Guerra, JM; Pinto, EG; Romanelli, MM; Tempone, AG; Torres-Santos, EC | 1 |
| Sun, W; Wang, C; Wang, H; Zhang, F; Zhou, Y; Zhou, Z | 1 |
| Krishnamurthy, S; Prajapati, SK | 1 |
| Gasparyan, A; Manzanares, J; Navarrete, F | 1 |
| Girgis-Gabardo, A; Gwynne, WD; Hassell, JA; Shakeel, MS | 1 |
| Appt, SE; Carr, JJ; Groban, L; Justice, JN; Kitzman, DW; Register, TC; Shively, CA; Silverstein-Metzler, MG | 1 |
| Appt, SE; Clarkson, TB; Justice, JN; Kritchevsky, SB; Register, TC; Shively, CA; Silverstein-Metzler, MG; Uberseder, B | 1 |
| Hasegawa, S; Hida, H; Miyake, Y; Mouri, A; Nabeshima, T; Noda, Y; Ozaki, N; Yamada, K; Yoshimi, A | 1 |
| Becerril-García, MA; González, GM; Méndez-Galomo, KS; Montoya, AM; Robledo-Leal, ER; Solís-Villegas, EM; Treviño-Rangel, RJ; Villanueva-Lozano, H | 1 |
| Chang, L; Chen, J; Hashimoto, K; Ishima, T; Ma, M; Pu, Y; Ren, Q; Xiong, Z; Zhang, K | 1 |
| Cheng, JH; Jiang, T; Jin, L; Jin, XJ; Lu, Y; Ma, J; Piao, HN; Piao, LX; Xu, X; Zhao, XD | 1 |
| Hooker, BL; McFadden, SL | 1 |
| Brummelte, S; Kott, JM; Mooney-Leber, SM | 1 |
| Abman, SH; Delaney, C; Gien, J; Isenberg, N; Kailey, J; Roe, G | 1 |
| Faingold, CL; Randall, M | 1 |
| Hult Lundh, S; Kirik, D; Nilsson, N; Petersén, Å; Soylu, R | 1 |
| Haskell, SE; Hermann, GM; Peotta, VA; Reinking, BE; Roghair, RD | 1 |
| Groban, L; Kitzman, DW; Register, TC; Shively, CA | 1 |
| Erkoseoglu, I; Kadioglu, M; Kalyoncu, NI; Kesim, M; Pepeoglu, D; Yanik, MN; Yaris, E | 1 |
| Furuse, K; Hashimoto, E; Ishii, T; Kigawa, Y; Saito, T; Shirasaka, T; Tsujino, H; Ukai, W | 1 |
| Abdollahifar, MA; Asadi-Golshan, R; Karbalay-Doust, S; Noorafshan, A; Rashidian-Rashidabadi, A | 1 |
| Chen, HX; Li, YF; Liu, YQ; Qiu, ZK; Xu, JP; Yang, RF; Zhang, LM; Zhang, YZ; Zhao, N | 1 |
| Fang, WW; Guo, WZ; Li, BW; Li, YF; Liu, J; Liu, Y; Miao, YL; Shi, WZ; Wu, W | 1 |
| Chengfeng, S; Lei, W; Lingjia, Q; Rui, Z; Wei, L; Xinxing, W | 1 |
| Cai, H; Gong, H; Jiang, P; Li, H; Liu, Y; Tang, M; Zhang, L | 1 |
| Appt, SE; Clarkson, TB; Register, TC; Shively, CA | 1 |
| Antoniou, K; Dalla, C; Kafetzopoulos, V; Kokras, N; Mikail, HG; Papadopoulou-Daifoti, Z | 1 |
| Alvarado, G; Artigas, F; Bortolozzi, A; Campa, L; Caso, JR; Ferrés-Coy, A; Galofré, M; Leza, JC; Montefeltro, A; Paz, V; Pazos, Á; Pilar-Cuéllar, F; Ruiz-Bronchal, E; Valdizán, EM; Vidal, R | 1 |
| Berk, M; Collier, FM; Dodd, S; Ellis, M; Fraher, D; Gibert, Y; Hodge, JM; Kennedy, RL; McMillan, JS; Nicholson, GC; Pasco, JA; Walder, K; Williams, LJ | 1 |
| Antoniazzi, CT; Barcelos, RC; Burger, ME; Duarte, MM; Duarte, T; Freitas, D; Metz, VG; Segat, HJ; Vey, LT | 1 |
| Dunn-Meynell, A; Levin, BE; Otlivanchik, O; Sanders, NM | 1 |
| Cai, H; Dang, R; Guo, Y; Jiang, P; Liang, D; Lv, C; Yang, R; Zhang, L; Zhu, Y | 1 |
| Bali, A; Jaggi, AS; Singh, N; Verma, M | 1 |
| García-Juárez, J; González, GM; Hernández-Rodríguez, P; Martínez-Reséndez, MF; Rodríguez-Rocha, H; Treviño-Rangel, Rde J; Villanueva-Lozano, H | 1 |
| Audi, EA; Cuman, RK; Maraschin, JC; Rangel, MP; Sestile, CC | 1 |
| Bagmetova, VV; Chernysheva, YV; Ozerov, AA; Tyurenkov, IN | 1 |
| Imamura, Y; Mouri, A; Murakami, Y; Nabeshima, T; Saito, K; Tashiro, T; Yamamoto, Y | 1 |
| Amidfar, M; Arbabi, M; Kim, YK; Quevedo, J; Réus, GZ | 1 |
| Adebayo, AN; Onaolapo, AY; Onaolapo, OJ | 1 |
| Davoudi, S; Heydari, A | 1 |
| Deshmukh, R; Gill, JS; Jamwal, S; Kumar, P | 1 |
| Aksoz, E; Aksoz, T; Bilge, SS; Celik, S; Diren, HB; Ilkaya, F | 1 |
| Coe, JW; Guanowsky, V; Mineur, YS; Picciotto, MR; Rollema, H; Seymour, PA; Shrikhande, A | 1 |
| Gaur, V; Kumar, A | 1 |
| Gil-Ad, I; Korob, I; Taler, M; Weizman, A | 1 |
| Andreasen, JT; Bate, S; Christiansen, S; Henningsen, K; Wiborg, O | 1 |
| Chan, G; Chevarin, C; Du, X; Hannan, AJ; Lanfumey, L; Leang, L; Pang, TY; Renoir, T; Zajac, MS | 1 |
| Chevarin, C; Du, X; Hannan, AJ; Lanfumey, L; Leang, L; Pang, TY; Renoir, T; Zajac, MS | 1 |
| Alvarado, G; Artigas, F; Bortolozzi, A; Carmona, MC; Castañé, A; Cortés, R; Fernández, G; Ferrés-Coy, A; Montefeltro, A; Perales, JC; Santana, N; Semakova, J; Toth, M | 1 |
| Bisgaard, CF; Christensen, T; Wiborg, O | 1 |
| Frazer, A; Furmaga, H; Shah, A | 1 |
| Bilge, U; Erol, K | 1 |
| Dalla, C; Kafetzopoulos, V; Kokras, N; Mikail, HG; Papadopoulou-Daifoti, Z | 1 |
| Baharav, E; Bar, M; Gil-Ad, I; Karp, L; Taler, M; Weinberger, A; Weizman, A | 1 |
| Bak, S; Bisgaard, CF; Christensen, T; Enghild, JJ; Jensen, ON; Wiborg, O | 1 |
| Aldana, BI; Gómez, CD; Nekrassov, V; Sitges, M | 1 |
| Abdel-Salam, OM; El-Shenawy, SM; Nofal, SM | 1 |
| Flynn, DM; Hill, RJ; Knight, DR; Magee, WP; Oleynek, JJ; Smith, AH; Tracey, WR | 1 |
| Bonikovski, V; Futuro-Neto, HA; Pires, JG | 1 |
| Cohen, H; Kaplan, Z; Matar, MA; Zohar, J | 1 |
| Duan, W; Jiang, M; Li, Q; Masuda, N; Peng, Q; Ross, CA; Zhao, M | 1 |
| Cadet, JL; Duan, W; Ford, E; Ladenheim, B; Masuda, N; Peng, Q; Ross, CA; Tryggestad, E; Wong, J; Zhao, M | 1 |
| Overstreet, DH; Pucilowski, O | 1 |
| Bourin, M; Redrobe, JP | 1 |
| Connor, TJ; Dredge, K; Harkin, A; Kelly, JP; Leonard, BE; McNamara, M; Redmond, A | 1 |
| Kriete, M; Rapoport, JL; Ryland, DH | 1 |
2 review(s) available for sertraline and Disease Models, Animal
| Article | Year |
|---|---|
The Role of Serotonin in Breast Cancer Stem Cells.
Topics: Animals; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survival; Disease Models, Animal; Docetaxel; Epithelial-Mesenchymal Transition; Female; Humans; Mice; Neoplasm Metastasis; Neoplasm Recurrence, Local; Neoplasm Transplantation; Neoplastic Stem Cells; Phenotype; Receptors, Serotonin; Remission Induction; Serotonin; Sertraline; Signal Transduction | 2021 |
Forced swim test: What about females?
Topics: Animals; Antidepressive Agents; Depressive Disorder; Disease Models, Animal; Dose-Response Relationship, Drug; Estrogens; Estrous Cycle; Female; Male; Motor Activity; Progesterone; Rats, Wistar; Sertraline; Sex Characteristics; Swimming; Testosterone | 2015 |
1 trial(s) available for sertraline and Disease Models, Animal
| Article | Year |
|---|---|
Drug treatment of canine acral lick. An animal model of obsessive-compulsive disorder.
Topics: 1-Naphthylamine; Animals; Clomipramine; Dermatitis; Desipramine; Disease Models, Animal; Dog Diseases; Dogs; Double-Blind Method; Fenfluramine; Fluoxetine; Follow-Up Studies; Grooming; Humans; Neurotransmitter Uptake Inhibitors; Obsessive-Compulsive Disorder; Serotonin; Sertraline; Ulcer | 1992 |
73 other study(ies) available for sertraline and Disease Models, Animal
| Article | Year |
|---|---|
Synthesis and pharmacological evaluation of 4-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrahydronaphthalenyl amines as triple reuptake inhibitors.
Topics: Animals; Antidepressive Agents; Disease Models, Animal; Dopamine; Drug Evaluation, Preclinical; Mice; Naphthalenes; Neurotransmitter Uptake Inhibitors; Norepinephrine; Serotonin | 2011 |
Inhibition of natriuretic peptide receptor 1 reduces itch in mice.
Topics: Animals; Behavior, Animal; Cell-Free System; Dermatitis, Contact; Disease Models, Animal; Ganglia, Spinal; Humans; Mice, Inbred C57BL; Mice, Knockout; Neurons; Pruritus; Receptors, Atrial Natriuretic Factor; Reproducibility of Results; Signal Transduction; Small Molecule Libraries | 2019 |
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Drug Evaluation, Preclinical; High-Throughput Screening Assays; Immunocompetence; Inhibitory Concentration 50; Methacycline; Mice, Inbred C57BL; Protease Inhibitors; Quantitative Structure-Activity Relationship; Small Molecule Libraries; Vero Cells; Zika Virus; Zika Virus Infection | 2020 |
Does Sertraline Affect Hypothalamic Food Intake Peptides in the Rat Experimental Model of Chronic Mild Stress-Induced Depression?
Topics: Animals; Depression; Disease Models, Animal; Eating; Hypothalamus; Male; Models, Theoretical; Neural Stem Cells; Peptides; Rats; Rats, Wistar; Sertraline; Stress, Psychological; Swimming | 2022 |
Investigations on Rho/ROCK signaling in post-traumatic stress disorder-like behavior in mice.
Topics: Animals; Anxiety; Corticosterone; Disease Models, Animal; Mice; Sertraline; Stress Disorders, Post-Traumatic | 2023 |
The preventive role of wheat germ oil against sertraline-induced testicular damage in male albino rats.
Topics: Animals; Antidepressive Agents; Disease Models, Animal; DNA Damage; Humans; Lipid Peroxidation; Male; Necrosis; Oxidative Stress; Plant Oils; Rats; Reactive Oxygen Species; Sertraline; Testicular Diseases; Testis | 2019 |
MicroRNA profiling identifies a novel compound with antidepressant properties.
Topics: Animals; Antidepressive Agents; Brain Injuries, Traumatic; Computational Biology; Depression; Disease Models, Animal; Estradiol; Fluoxetine; Gene Expression Regulation; Hippocampus; Humans; Imipramine; MicroRNAs; Rats; Sertraline; Sulfonamides; Thiazoles | 2019 |
Inducing and exploiting vulnerabilities for the treatment of liver cancer.
Topics: Animals; Apoptosis; Cell Cycle Proteins; Cell Line, Tumor; Cellular Senescence; Disease Models, Animal; Female; Liver Neoplasms; Male; Mice; Mice, Inbred BALB C; Molecular Targeted Therapy; Mutation; Protein Serine-Threonine Kinases; Sertraline; Signal Transduction; TOR Serine-Threonine Kinases; Tumor Suppressor Protein p53 | 2019 |
Sertraline Reduces Albuminuria by Interfering with Caveolae-Mediated Endocytosis through Glomerular Endothelial and Epithelial Cells.
Topics: Albumins; Albuminuria; Animals; Caveolae; Caveolin 1; Cells, Cultured; Disease Models, Animal; Dynamins; Endocytosis; Endothelial Cells; Humans; Male; Mice; Nephrotic Syndrome; Podocytes; Primary Cell Culture; Puromycin Aminonucleoside; Sertraline | 2019 |
Rapid anti-PTSD-like activity of the TSPO agonist YL-IPA08: Emphasis on brain GABA, neurosteroids and HPA axis function.
Topics: Animals; Behavior, Animal; Carrier Proteins; Corticosterone; Disease Models, Animal; gamma-Aminobutyric Acid; Hippocampus; Hypothalamo-Hypophyseal System; Imidazoles; Male; Prefrontal Cortex; Pregnanolone; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Selective Serotonin Reuptake Inhibitors; Sertraline; Stress Disorders, Post-Traumatic | 2020 |
Sertraline Delivered in Phosphatidylserine Liposomes Is Effective in an Experimental Model of Visceral Leishmaniasis.
Topics: Animals; Antiprotozoal Agents; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Immunomodulation; Leishmania donovani; Leishmaniasis, Visceral; Liposomes; Liver; Macrophages; Mice; Mice, Inbred BALB C; Phosphatidylserines; Sertraline; Spleen | 2019 |
Ginsenoside Rg1 fails to rescue PTSD-like behaviors in a mice model of single-prolonged stress.
Topics: Adrenocorticotropic Hormone; Animals; Behavior, Animal; Disease Models, Animal; Ginsenosides; Hippocampus; Male; Mice, Inbred C57BL; Neurogenesis; Sertraline; Stress Disorders, Post-Traumatic; Stress, Psychological | 2020 |
Development and treatment of cognitive inflexibility in sub-chronic stress-re-stress (SRS) model of PTSD.
Topics: Acetylcholine; Animals; Cholinesterase Inhibitors; Cognition Disorders; Disease Models, Animal; Donepezil; Hippocampus; Male; Prefrontal Cortex; Rats; Rats, Wistar; Selective Serotonin Reuptake Inhibitors; Sertraline; Stress Disorders, Post-Traumatic | 2021 |
The administration of sertraline plus naltrexone reduces ethanol consumption and motivation in a long-lasting animal model of post-traumatic stress disorder.
Topics: Alcohol Deterrents; Alcohol Drinking; Animals; Antidepressive Agents; Disease Models, Animal; Drug Therapy, Combination; Male; Mice; Mice, Inbred C57BL; Motivation; Naltrexone; Self Administration; Serotonin Plasma Membrane Transport Proteins; Sertraline; Stress Disorders, Post-Traumatic; Stress, Psychological; Time Factors | 2021 |
Long-term sertraline treatment and depression effects on carotid artery atherosclerosis in premenopausal female primates.
Topics: Animals; Carotid Artery Diseases; Carotid Artery, Common; Depression; Disease Models, Animal; Female; Hot Flashes; Humans; Longitudinal Studies; Macaca fascicularis; Premenopause; Primates; Random Allocation; Risk Factors; Selective Serotonin Reuptake Inhibitors; Sertraline | 2017 |
Relationships of depressive behavior and sertraline treatment with walking speed and activity in older female nonhuman primates.
Topics: Aged; Aging; Analysis of Variance; Animals; Antidepressive Agents; Depression; Disease Models, Animal; Female; Haplorhini; Humans; Random Allocation; Reference Values; Sertraline; Treatment Outcome; Walking Speed | 2017 |
Dysfunction of Serotonergic and Dopaminergic Neuronal Systems in the Antidepressant-Resistant Impairment of Social Behaviors Induced by Social Defeat Stress Exposure as Juveniles.
Topics: Animals; Antidepressive Agents; Aripiprazole; Brain; Depressive Disorder, Treatment-Resistant; Desipramine; Disease Models, Animal; Dominance-Subordination; Dopamine; Drug Therapy, Combination; Male; Mice, Inbred C57BL; Mice, Inbred ICR; Norepinephrine; Serotonin; Sertraline; Sexual Maturation; Social Behavior; Stress, Psychological | 2018 |
In vivo evaluation of the antifungal activity of sertraline against Aspergillus fumigatus.
Topics: Animals; Antifungal Agents; Aspergillosis; Aspergillus fumigatus; Colony Count, Microbial; Disease Models, Animal; Galactose; Histocytochemistry; Lepidoptera; Lung; Male; Mannans; Mice, Inbred BALB C; Sertraline; Survival Analysis; Treatment Outcome | 2019 |
Lack of rapid antidepressant effects of Kir4.1 channel inhibitors in a chronic social defeat stress model: Comparison with (R)-ketamine.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Depression; Depressive Disorder; Disease Models, Animal; Hippocampus; Ketamine; Male; Mice; Mice, Inbred C57BL; Mice, Inbred ICR; Potassium Channels, Inwardly Rectifying; Quinacrine; Sertraline; Stress, Psychological | 2019 |
Sertraline ameliorates inflammation in CUMS mice and inhibits TNF-α-induced inflammation in microglia cells.
Topics: Animals; Anti-Inflammatory Agents; Antidepressive Agents; Cell Line; Depression; Disease Models, Animal; Humans; Inflammation Mediators; Male; Mice; Mice, Inbred C57BL; Microglia; NF-kappa B; Receptors, Tumor Necrosis Factor; Sertraline; Signal Transduction; Transaminases; Tumor Necrosis Factor-alpha | 2019 |
Comparing Perika St. John's Wort and Sertraline for Treatment of Posttraumatic Stress Disorder in Mice.
Topics: Animals; Disease Models, Animal; Hypericum; Mice; Mice, Inbred C57BL; Phytotherapy; Plant Extracts; Reflex, Startle; Selective Serotonin Reuptake Inhibitors; Sertraline; Stress Disorders, Post-Traumatic | 2020 |
Developmental outcomes after gestational antidepressant treatment with sertraline and its discontinuation in an animal model of maternal depression.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Corticosterone; Depression; Depressive Disorder; Disease Models, Animal; Exploratory Behavior; Female; Male; Maternal Behavior; Postpartum Period; Pregnancy; Pregnancy Complications; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Sertraline; Sex Factors; Stress, Psychological | 2019 |
Serotonin contributes to high pulmonary vascular tone in a sheep model of persistent pulmonary hypertension of the newborn.
Topics: Adult; Animals; Cells, Cultured; Disease Models, Animal; Endothelial Cells; Familial Primary Pulmonary Hypertension; Fetus; Gene Expression; Humans; Hypertension, Pulmonary; Infant, Newborn; Ketanserin; Lung; Pulmonary Artery; Receptor, Serotonin, 5-HT2A; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin 5-HT2 Receptor Antagonists; Sertraline; Sheep, Domestic; Tryptophan Hydroxylase; Vascular Resistance | 2013 |
Effects of age, sex, and sertraline administration on seizure-induced respiratory arrest in the DBA/1 mouse model of sudden unexpected death in epilepsy (SUDEP).
Topics: Acoustic Stimulation; Aging; Animals; Death, Sudden; Disease Models, Animal; Dose-Response Relationship, Drug; Epilepsy, Reflex; Female; Male; Mice; Mice, Inbred DBA; Respiratory Insufficiency; Selective Serotonin Reuptake Inhibitors; Sertraline; Sex Characteristics | 2013 |
Hypothalamic expression of mutant huntingtin contributes to the development of depressive-like behavior in the BAC transgenic mouse model of Huntington's disease.
Topics: Animals; Anxiety; Behavior, Animal; Depression; Disease Models, Animal; Female; Humans; Huntingtin Protein; Huntington Disease; Hypothalamus; Male; Mice; Mice, Transgenic; Nerve Tissue Proteins; Neuropeptide Y; Receptors, Tachykinin; Sertraline; Vesicular Monoamine Transport Proteins | 2013 |
Impact of neonatal sertraline exposure on the post-myocardial infarction outcomes of adult male mice.
Topics: Animals; Animals, Newborn; Disease Models, Animal; Echocardiography; Hypoplastic Left Heart Syndrome; Male; Mice; Mice, Inbred C57BL; Myocardial Infarction; Selective Serotonin Reuptake Inhibitors; Sertraline; Survival Rate; Telemetry; Time Factors | 2013 |
Effect of depression and sertraline treatment on cardiac function in female nonhuman primates.
Topics: Analysis of Variance; Animals; Atherosclerosis; Body Weights and Measures; Comorbidity; Depression; Diet; Disease Models, Animal; Echocardiography; Female; Heart; Heart Failure; Heart Rate; Humans; Hydroxyindoleacetic Acid; Macaca fascicularis; Male; Myocardium; Placebos; Random Allocation; Selective Serotonin Reuptake Inhibitors; Sertraline | 2014 |
The evaluation of analgesic effects of milnacipran and sertraline in tail-flick test.
Topics: Analgesics; Animals; Cyclopropanes; Disease Models, Animal; Mice; Mice, Inbred BALB C; Milnacipran; Pain; Pain Measurement; Pain Threshold; Selective Serotonin Reuptake Inhibitors; Sertraline; Tail; Time Factors; Treatment Outcome | 2014 |
Stem cell therapy: a new approach to the treatment of refractory depression.
Topics: Animals; Antidepressive Agents; Brain; Combined Modality Therapy; Depressive Disorder, Treatment-Resistant; Disease Models, Animal; Disks Large Homolog 4 Protein; GABAergic Neurons; Intracellular Signaling Peptides and Proteins; Membrane Proteins; Neural Stem Cells; Parvalbumins; Rats, Wistar; Sertraline; Stem Cell Transplantation | 2014 |
Curcumin and sertraline prevent the reduction of the number of neurons and glial cells and the volume of rats' medial prefrontal cortex induced by stress.
Topics: Animals; Cell Count; Curcumin; Disease Models, Animal; Male; Neuroglia; Neurons; Neuroprotective Agents; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Sertraline; Statistics, Nonparametric; Stress, Psychological | 2014 |
Anxiolytic-like effects of YL-IPA08, a potent ligand for the translocator protein (18 kDa) in animal models of post-traumatic stress disorder.
Topics: Analysis of Variance; Animals; Anti-Anxiety Agents; Disease Models, Animal; Dose-Response Relationship, Drug; Electroshock; Freezing Reaction, Cataleptic; Imidazoles; Isoquinolines; Male; Mice; Mice, Inbred ICR; Motor Activity; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, GABA; Sertraline; Stress Disorders, Post-Traumatic | 2014 |
Midazolam ameliorates the behavior deficits of a rat posttraumatic stress disorder model through dual 18 kDa translocator protein and central benzodiazepine receptor and neurosteroidogenesis.
Topics: Animals; Anti-Anxiety Agents; Antidepressive Agents; Anxiety; Carrier Proteins; Disease Models, Animal; Fear; Male; Maze Learning; Midazolam; Neurotransmitter Agents; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Sertraline; Stress Disorders, Post-Traumatic | 2014 |
Hyperhomocysteinemia is a result, rather than a cause, of depression under chronic stress.
Topics: Animals; Behavior, Animal; Betaine-Homocysteine S-Methyltransferase; Chronic Disease; Depression; Disease Models, Animal; Homocysteine; Hyperhomocysteinemia; Male; Methionine; Rats, Wistar; Recombinant Proteins; Sertraline; Stress, Psychological | 2014 |
Antidepressant-like effect of n-3 PUFAs in CUMS rats: role of tPA/PAI-1 system.
Topics: Animals; Antidepressive Agents; Body Weight; Brain-Derived Neurotrophic Factor; Chronic Disease; Depressive Disorder; Disease Models, Animal; Fatty Acids, Omega-3; Hippocampus; Plasminogen Activator Inhibitor 1; Prefrontal Cortex; Random Allocation; Rats, Sprague-Dawley; Sertraline; Stress, Psychological; Tissue Plasminogen Activator | 2015 |
Effects of long-term sertraline treatment and depression on coronary artery atherosclerosis in premenopausal female primates.
Topics: Animals; Atherosclerosis; Behavior, Animal; Coronary Artery Disease; Coronary Vessels; Depressive Disorder; Disease Models, Animal; Female; Iliac Artery; Longitudinal Studies; Macaca fascicularis; Premenopause; Risk Factors; Selective Serotonin Reuptake Inhibitors; Sertraline | 2015 |
Therapeutic antidepressant potential of a conjugated siRNA silencing the serotonin transporter after intranasal administration.
Topics: Administration, Intranasal; Animals; Antidepressive Agents; Arabidopsis Proteins; Brain; Corticosterone; Depression; Disease Models, Animal; DNA, Antisense; Endocytosis; Exploratory Behavior; Fluoxetine; Gene Expression Regulation; Intramolecular Transferases; Male; Mice; Mice, Inbred C57BL; Neurons; Phosphopyruvate Hydratase; RNA, Small Interfering; Serotonin; Serotonin Plasma Membrane Transport Proteins; Sertraline; Time Factors | 2016 |
Citalopram and sertraline exposure compromises embryonic bone development.
Topics: Animals; Apoptosis; Bone and Bones; Calcification, Physiologic; Cartilage; Cells, Cultured; Citalopram; Disease Models, Animal; Humans; Mesenchymal Stem Cells; Osteoblasts; Osteogenesis; Selective Serotonin Reuptake Inhibitors; Sertraline; Zebrafish | 2016 |
Neonatal tactile stimulation decreases depression-like and anxiety-like behaviors and potentiates sertraline action in young rats.
Topics: Age Factors; Analysis of Variance; Animals; Animals, Newborn; Anxiety; Corticosterone; Depression; Disease Models, Animal; Female; Hydrocortisone; Male; Maze Learning; Physical Stimulation; Pregnancy; Rats; Rats, Wistar; Selective Serotonin Reuptake Inhibitors; Sertraline; Swimming; Touch | 2015 |
Orexin signaling is necessary for hypoglycemia-induced prevention of conditioned place preference.
Topics: Animals; Arousal; Behavior, Animal; Benzoxazoles; Blood Glucose; Brain; Conditioning, Psychological; Disease Models, Animal; Feeding Behavior; Hypoglycemia; Male; Naphthyridines; Orexin Receptor Antagonists; Orexin Receptors; Orexins; Rats, Sprague-Dawley; Reward; Sertraline; Signal Transduction; Time Factors; Urea | 2016 |
Dysregulation of Neuregulin-1/ErbB signaling in the prefrontal cortex and hippocampus of rats exposed to chronic unpredictable mild stress.
Topics: Analysis of Variance; Animals; Antidepressive Agents; Corticosterone; Disease Models, Animal; Food Preferences; Hippocampus; Male; Neuregulin-1; Oncogene Proteins v-erbB; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Sertraline; Signal Transduction; Stress, Psychological; Swimming | 2016 |
Investigating the role of nisoldipine in foot-shock-induced post-traumatic stress disorder in mice.
Topics: Animals; Anxiety; Behavior, Animal; Corticosterone; Disease Models, Animal; Electroshock; Mice; Motor Activity; Nisoldipine; Sertraline; Stress Disorders, Post-Traumatic; Stress, Psychological | 2016 |
Activity of sertraline against Cryptococcus neoformans: in vitro and in vivo assays.
Topics: Animal Structures; Animals; Antifungal Agents; Colony Count, Microbial; Cryptococcosis; Cryptococcus neoformans; Disease Models, Animal; Fungemia; Histocytochemistry; Humans; Male; Mice; Sertraline; Treatment Outcome | 2016 |
Antidepressant-like Effect of Insulin in Streptozotocin-induced Type 2 Diabetes Mellitus Rats.
Topics: Animals; Antidepressive Agents; Blood Glucose; Diabetes Mellitus, Experimental; Disease Models, Animal; Glucose Intolerance; Insulin; Male; Rats; Rats, Wistar; Selective Serotonin Reuptake Inhibitors; Sertraline; Weight Gain | 2016 |
Comparison of the Efficiency of Adeprophen and Antidepressants of Various Groups on the Model of Reserpine-Induced Depression in Rats.
Topics: Adenine; Amitriptyline; Animals; Antidepressive Agents; Behavior, Animal; Depression; Disease Models, Animal; Fluoxetine; Food Preferences; Imipramine; Male; Motor Activity; Paroxetine; Rats; Reserpine; Sertraline; Venlafaxine Hydrochloride | 2016 |
Kynurenine 3-monooxygenase is implicated in antidepressants-responsive depressive-like behaviors and monoaminergic dysfunctions.
Topics: Animals; Antidepressive Agents; Biogenic Monoamines; Depressive Disorder, Major; Disease Models, Animal; Exploratory Behavior; Food Preferences; Hippocampus; Imipramine; Kynurenine; Kynurenine 3-Monooxygenase; Maze Learning; Mice; Mice, Inbred C57BL; Mice, Knockout; Sertraline; Sucrose; Swimming; Tryptophan | 2017 |
Effect of co-administration of memantine and sertraline on the antidepressant-like activity and brain-derived neurotrophic factor (BDNF) levels in the rat brain.
Topics: Animals; Antidepressive Agents; Brain; Brain-Derived Neurotrophic Factor; Depressive Disorder; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Therapy, Combination; Excitatory Amino Acid Antagonists; Male; Memantine; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Sertraline | 2017 |
Exogenous daytime melatonin modulates response of adolescent mice in a repeated unpredictable stress paradigm.
Topics: Age Factors; Animals; Anti-Anxiety Agents; Antioxidants; Behavior, Animal; Biomarkers; Brain; Chronic Disease; Corticosterone; Diazepam; Disease Models, Animal; Grooming; Male; Maze Learning; Melatonin; Memory, Short-Term; Mice; Motor Activity; Nitric Oxide; Oxidative Stress; Sertraline; Spatial Memory; Stress, Psychological; Superoxide Dismutase; Time Factors | 2017 |
The effect of sertraline and 8-OH-DPAT on the PTZ_induced seizure threshold: Role of the nitrergic system.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Analysis of Variance; Animals; Convulsants; Disease Models, Animal; Dose-Response Relationship, Drug; Male; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide; Pentylenetetrazole; Piperazines; Pyridines; Seizures; Selective Serotonin Reuptake Inhibitors; Serotonin Antagonists; Sertraline | 2017 |
Sertraline and venlafaxine improves motor performance and neurobehavioral deficit in quinolinic acid induced Huntington's like symptoms in rats: Possible neurotransmitters modulation.
Topics: Animals; Corpus Striatum; Disease Models, Animal; gamma-Aminobutyric Acid; Glutamic Acid; Huntington Disease; Interleukin-1beta; Interleukin-6; Lipid Peroxidation; Male; Motor Activity; Neuroprotective Agents; Neurotransmitter Agents; Oxidative Stress; Quinolinic Acid; Rats; Rats, Wistar; Rotarod Performance Test; Sertraline; Tumor Necrosis Factor-alpha; Venlafaxine Hydrochloride | 2017 |
Antidepressant-like effects of echo-planar magnetic resonance imaging in mice determined using the forced swimming test.
Topics: Analysis of Variance; Animals; Antidepressive Agents; Behavior, Animal; Depression; Desipramine; Disease Models, Animal; Echo-Planar Imaging; Immobility Response, Tonic; Male; Mice; Mice, Inbred BALB C; Motor Activity; Sertraline; Swimming; Time Factors | 2008 |
Varenicline has antidepressant-like activity in the forced swim test and augments sertraline's effect.
Topics: Animals; Antidepressive Agents; Benzazepines; Depression; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Mice; Mice, Inbred C57BL; Mice, Inbred ICR; Nicotinic Agonists; Quinoxalines; Receptors, Nicotinic; Selective Serotonin Reuptake Inhibitors; Sertraline; Swimming; Varenicline | 2009 |
Behavioral, biochemical and cellular correlates in the protective effect of sertraline against transient global ischemia induced behavioral despair: possible involvement of nitric oxide-cyclic guanosine monophosphate study pathway.
Topics: Adult; Animals; Antidepressive Agents; Behavior, Animal; Cell Respiration; Cyclic GMP; Depression; Disease Models, Animal; Enzyme Inhibitors; Humans; Ischemic Attack, Transient; Mice; Motor Activity; Neuroprotective Agents; Neuropsychological Tests; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Oxidative Stress; Random Allocation; Reperfusion Injury; Sertraline | 2010 |
The immunomodulatory effect of the antidepressant sertraline in an experimental autoimmune encephalomyelitis mouse model of multiple sclerosis.
Topics: Animals; Antidepressive Agents; Cell Survival; Cytokines; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Female; Immunologic Factors; Lymphocytes; Mice; Mice, Inbred C57BL; Multiple Sclerosis; Selective Serotonin Reuptake Inhibitors; Sertraline | 2011 |
Nicotine reverses anhedonic-like response and cognitive impairment in the rat chronic mild stress model of depression: comparison with sertraline.
Topics: Anhedonia; Animals; Antidepressive Agents; Behavior, Animal; Cognition Disorders; Depression; Disease Models, Animal; Drug Therapy, Combination; Male; Nicotine; Nicotinic Agonists; Rats; Rats, Wistar; Sertraline; Stress, Psychological; Sucrose | 2011 |
Treatment of depressive-like behaviour in Huntington's disease mice by chronic sertraline and exercise.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Cell Proliferation; Depressive Disorder; Disease Models, Animal; Female; Gene Expression; Hippocampus; Huntington Disease; Mice; Mice, Transgenic; Physical Conditioning, Animal; Receptor, Serotonin, 5-HT1A; Receptor, Serotonin, 5-HT2A; Serotonin 5-HT1 Receptor Agonists; Serotonin 5-HT2 Receptor Agonists; Sertraline; Swimming | 2012 |
Sexually dimorphic serotonergic dysfunction in a mouse model of Huntington's disease and depression.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Behavior, Animal; Depression; Disease Models, Animal; Feeding Behavior; Female; Gene Expression Regulation; Huntington Disease; Hydroxyindoleacetic Acid; Hyperthermia, Induced; Male; Mice; Mutation; Raphe Nuclei; Receptor, Serotonin, 5-HT1A; Receptor, Serotonin, 5-HT2A; Serotonin; Sertraline; Sex Characteristics; Swimming | 2011 |
Selective siRNA-mediated suppression of 5-HT1A autoreceptors evokes strong anti-depressant-like effects.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Administration, Intranasal; Animals; Antidepressive Agents; Autoreceptors; Depression; Disease Models, Animal; Drug Combinations; Drug Design; Fluoxetine; Hippocampus; Hypothermia; Infusions, Intraventricular; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Prefrontal Cortex; Receptor, Serotonin, 5-HT1A; RNA, Small Interfering; Serotonergic Neurons; Sertraline | 2012 |
Biomarkers of anhedonic-like behavior, antidepressant drug refraction, and stress resilience in a rat model of depression.
Topics: Anhedonia; Animals; Biomarkers; Citalopram; Depression; Disease Models, Animal; Drug Resistance; Eating; Gene Expression Profiling; Hippocampus; Humans; Male; Rats; Rats, Wistar; Selective Serotonin Reuptake Inhibitors; Sertraline; Stress, Psychological; Sucrose | 2011 |
Serotonergic and noradrenergic pathways are required for the anxiolytic-like and antidepressant-like behavioral effects of repeated vagal nerve stimulation in rats.
Topics: 5,7-Dihydroxytryptamine; Adrenergic Agents; Adrenergic Uptake Inhibitors; Analysis of Variance; Animals; Anxiety; Autoradiography; Brain; Desipramine; Disease Models, Animal; Drug Delivery Systems; Exploratory Behavior; Feeding Behavior; Imipramine; Immobility Response, Tonic; Male; Neural Pathways; Norepinephrine; Oxidopamine; Protein Binding; Rats; Rats, Sprague-Dawley; Reaction Time; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Agents; Serotonin Antagonists; Sertraline; Swimming; Time Factors; Tritium; Vagus Nerve Stimulation | 2011 |
Effects of sertraline on experimental mouse models of psychosis.
Topics: Animals; Antidepressive Agents; Apomorphine; Catalepsy; Dextroamphetamine; Disease Models, Animal; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Haloperidol; Mice; Motor Activity; Psychotic Disorders; Selective Serotonin Reuptake Inhibitors; Sertraline; Time Factors | 2012 |
Sertraline behavioral response associates closer and dose-dependently with cortical rather than hippocampal serotonergic activity in the rat forced swim stress.
Topics: Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Hippocampus; Hydroxyindoleacetic Acid; Immobility Response, Tonic; Male; Prefrontal Cortex; Rats; Rats, Wistar; Serotonergic Neurons; Serotonin; Sertraline; Stress, Psychological; Swimming | 2012 |
Immunomodulatory effect of sertraline in a rat model of rheumatoid arthritis.
Topics: Analysis of Variance; Animals; Arthritis, Rheumatoid; Concanavalin A; Cyclooxygenase 2; Cytokines; Cytotoxicity Tests, Immunologic; Disability Evaluation; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Freund's Adjuvant; Immunologic Factors; Methotrexate; Rats; Rats, Inbred Lew; Sertraline; Spleen; Thymidine | 2012 |
Vesicular signalling and immune modulation as hedonic fingerprints: proteomic profiling in the chronic mild stress depression model.
Topics: Anhedonia; Animals; Citalopram; Depression; Disease Models, Animal; Hippocampus; Immune System; Laser Capture Microdissection; Male; Protein Processing, Post-Translational; Proteins; Proteomics; Rats; Rats, Wistar; Selective Serotonin Reuptake Inhibitors; Sertraline; Signal Transduction; Stress, Psychological; Tandem Mass Spectrometry; Two-Dimensional Difference Gel Electrophoresis | 2012 |
The antidepressant sertraline prevents the behavioral and EEG changes induced in two animal models of seizures.
Topics: 4-Aminopyridine; Animals; Anticonvulsants; Brain; Carbamazepine; Disease Models, Animal; Electroencephalography; Exploratory Behavior; Male; Pentylenetetrazole; Rats; Rats, Wistar; Seizures; Sertraline; Vocalization, Animal | 2012 |
Evaluation of the anti-inflammatory and anti-nociceptive effects of different antidepressants in the rat.
Topics: Amitriptyline; Analysis of Variance; Animals; Antidepressive Agents; Carrageenan; Clomipramine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Electroshock; Fluoxetine; Imipramine; Inflammation; Male; Pain; Pain Measurement; Rats; Rats, Sprague-Dawley; Sertraline; Trazodone | 2003 |
Novel N6-substituted adenosine 5'-N-methyluronamides with high selectivity for human adenosine A3 receptors reduce ischemic myocardial injury.
Topics: Adenosine; Adenosine A3 Receptor Agonists; Animals; CHO Cells; Cricetinae; Disease Models, Animal; Dose-Response Relationship, Drug; Furans; Humans; Iodine Radioisotopes; Isoxazoles; Myocardial Infarction; Myocardial Reperfusion Injury; Purines; Rabbits; Radioligand Assay; Receptor, Adenosine A3; Sertraline; Transfection | 2003 |
Acute effects of selective serotonin reuptake inhibitors on neuroleptic-induced catalepsy in mice.
Topics: Animals; Anti-Dyskinesia Agents; Catalepsy; Disease Models, Animal; Female; Fluoxetine; Haloperidol; Male; Mice; Paroxetine; Selective Serotonin Reuptake Inhibitors; Sertraline; Sex Factors; Time Factors | 2005 |
The effect of early poststressor intervention with sertraline on behavioral responses in an animal model of post-traumatic stress disorder.
Topics: Animals; Anxiety Disorders; Avoidance Learning; Behavior, Animal; Behavioral Symptoms; Brain; Disease Models, Animal; Drug Administration Schedule; Male; Predatory Behavior; Psychomotor Agitation; Rats; Rats, Sprague-Dawley; Reflex, Startle; Selective Serotonin Reuptake Inhibitors; Serotonin; Sertraline; Stress Disorders, Post-Traumatic; Stress, Psychological; Time Factors | 2006 |
The antidepressant sertraline improves the phenotype, promotes neurogenesis and increases BDNF levels in the R6/2 Huntington's disease mouse model.
Topics: Age Factors; Animals; Antidepressive Agents; Behavior, Animal; Brain; Brain-Derived Neurotrophic Factor; Bromodeoxyuridine; Cell Proliferation; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Huntington Disease; Male; Mice; Mice, Transgenic; Motor Activity; Nerve Tissue Proteins; Neurons; Phenotype; Sertraline | 2008 |
Sertraline slows disease progression and increases neurogenesis in N171-82Q mouse model of Huntington's disease.
Topics: Animals; Asparagine; Cell Differentiation; Cell Movement; Disease Models, Animal; Disease Progression; Glutamine; Huntington Disease; Male; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Transgenic; Neurons; Sertraline | 2008 |
Effect of chronic antidepressant treatment on responses to apomorphine in selectively bred rat strains.
Topics: 1-Naphthylamine; Animals; Apomorphine; Body Temperature Regulation; Breeding; Depressive Disorder; Desipramine; Disease Models, Animal; Male; Motor Activity; Parasympathetic Nervous System; Rats; Sertraline; Time Factors | 1993 |
Dose-dependent influence of buspirone on the activities of selective serotonin reuptake inhibitors in the mouse forced swimming test.
Topics: Animals; Antidepressive Agents; Buspirone; Citalopram; Depression; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Exercise Test; Fluoxetine; Fluvoxamine; Male; Mice; Motor Activity; Paroxetine; Selective Serotonin Reuptake Inhibitors; Sertraline; Swimming | 1998 |
Activity and onset of action of reboxetine and effect of combination with sertraline in an animal model of depression.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amygdala; Analgesics; Animals; Antidepressive Agents; Body Temperature; Clonidine; Depression; Disease Models, Animal; Drug Therapy, Combination; Exploratory Behavior; Hydroxyindoleacetic Acid; Male; Morpholines; Motor Activity; Olfactory Bulb; Rats; Rats, Sprague-Dawley; Reboxetine; Serotonin Receptor Agonists; Sertraline; Swimming | 1999 |