serine has been researched along with Xeroderma Pigmentosum in 4 studies
Serine: A non-essential amino acid occurring in natural form as the L-isomer. It is synthesized from GLYCINE or THREONINE. It is involved in the biosynthesis of PURINES; PYRIMIDINES; and other amino acids.
serine : An alpha-amino acid that is alanine substituted at position 3 by a hydroxy group.
Xeroderma Pigmentosum: A rare, pigmentary, and atrophic autosomal recessive disease. It is manifested as an extreme photosensitivity to ULTRAVIOLET RAYS as the result of a deficiency in the enzyme that permits excisional repair of ultraviolet-damaged DNA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Treatment with lactacystin (an inhibitor of the proteasome) or heat shock leads to similar levels of p53 accumulation in normal and AT fibroblasts, but the p53 protein lacks a phosphorylated serine 15." | 1.30 | Requirement of ATM in phosphorylation of the human p53 protein at serine 15 following DNA double-strand breaks. ( Nakagawa, K; Tamai, K; Taya, Y; Yamaizumi, M, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (50.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bito, T | 1 |
| Sumita, N | 1 |
| Masaki, T | 1 |
| Shirakawa, T | 1 |
| Ueda, M | 1 |
| Yoshiki, R | 1 |
| Tokura, Y | 1 |
| Nishigori, C | 1 |
| Valerie, K | 1 |
| Nakagawa, K | 1 |
| Taya, Y | 1 |
| Tamai, K | 1 |
| Yamaizumi, M | 1 |
| Ljungman, M | 1 |
| O'Hagan, HM | 1 |
| Paulsen, MT | 1 |
4 other studies available for serine and Xeroderma Pigmentosum
| Article | Year |
|---|---|
Ultraviolet light induces Stat3 activation in human keratinocytes and fibroblasts through reactive oxygen species and DNA damage.
Topics: Binding Sites; Cells, Cultured; DNA Damage; Fibroblasts; Humans; Keratinocytes; Phosphorylation; Rea | 2010 |
Replacing tryptophan-128 of T4 endonuclease V with a serine residue results in decreased enzymatic activity in vitro and in vivo.
Topics: Base Sequence; Cells, Cultured; Deoxyribonuclease (Pyrimidine Dimer); Deoxyribonuclease IV (Phage T4 | 1995 |
Requirement of ATM in phosphorylation of the human p53 protein at serine 15 following DNA double-strand breaks.
Topics: Acetylcysteine; Ataxia Telangiectasia; Ataxia Telangiectasia Mutated Proteins; Cell Cycle Proteins; | 1999 |
Induction of ser15 and lys382 modifications of p53 by blockage of transcription elongation.
Topics: Acetylation; Cell Nucleus; Cells, Cultured; Cockayne Syndrome; DNA Damage; Gene Expression Regulatio | 2001 |