serine has been researched along with Tuberculosis in 12 studies
Serine: A non-essential amino acid occurring in natural form as the L-isomer. It is synthesized from GLYCINE or THREONINE. It is involved in the biosynthesis of PURINES; PYRIMIDINES; and other amino acids.
serine : An alpha-amino acid that is alanine substituted at position 3 by a hydroxy group.
Tuberculosis: Any of the infectious diseases of man and other animals caused by species of MYCOBACTERIUM TUBERCULOSIS.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Herein, we demonstrated that the Mycobacterium tuberculosis EthR, a transcriptional repressor that regulates the activation process of the antitubercular drug ethionamide (ETH) is a specific substrate of the mycobacterial kinase PknF." | 7.80 | The Mycobacterium tuberculosis transcriptional repressor EthR is negatively regulated by Serine/Threonine phosphorylation. ( Baulard, A; Blondiaux, N; Carrère-Kremer, S; Dimala, MM; Kremer, L; Leiba, J; Molle, V; Wohlkönig, A, 2014) |
| " Herein, we demonstrated that the Mycobacterium tuberculosis EthR, a transcriptional repressor that regulates the activation process of the antitubercular drug ethionamide (ETH) is a specific substrate of the mycobacterial kinase PknF." | 3.80 | The Mycobacterium tuberculosis transcriptional repressor EthR is negatively regulated by Serine/Threonine phosphorylation. ( Baulard, A; Blondiaux, N; Carrère-Kremer, S; Dimala, MM; Kremer, L; Leiba, J; Molle, V; Wohlkönig, A, 2014) |
| "D-cycloserine (D-CS) is a second-line antibiotic for TB that inhibits bacterial cell wall synthesis." | 1.91 | Heterologous production of the D-cycloserine intermediate O-acetyl-L-serine in a human type II pulmonary cell model. ( Balaram, A; Conrad, WH; Dejneka, S; McMahon, M; Najibi, Z; Pawlowicz, P; Robbins, L, 2023) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 10 (83.33) | 24.3611 |
| 2020's | 2 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Babin, BM | 1 |
| Keller, LJ | 1 |
| Pinto, Y | 1 |
| Li, VL | 1 |
| Eneim, AS | 1 |
| Vance, SE | 1 |
| Terrell, SM | 1 |
| Bhatt, AS | 1 |
| Long, JZ | 1 |
| Bogyo, M | 1 |
| Robbins, L | 1 |
| Balaram, A | 1 |
| Dejneka, S | 1 |
| McMahon, M | 1 |
| Najibi, Z | 1 |
| Pawlowicz, P | 1 |
| Conrad, WH | 1 |
| Wipperman, MF | 1 |
| Heaton, BE | 1 |
| Nautiyal, A | 1 |
| Adefisayo, O | 1 |
| Evans, H | 1 |
| Gupta, R | 1 |
| van Ditmarsch, D | 1 |
| Soni, R | 1 |
| Hendrickson, R | 1 |
| Johnson, J | 1 |
| Krogan, N | 1 |
| Glickman, MS | 1 |
| Cho, HY | 1 |
| Kang, BS | 1 |
| Leiba, J | 1 |
| Carrère-Kremer, S | 1 |
| Blondiaux, N | 1 |
| Dimala, MM | 1 |
| Wohlkönig, A | 1 |
| Baulard, A | 1 |
| Kremer, L | 1 |
| Molle, V | 1 |
| Boshoff, HI | 1 |
| Pavlov, VA | 1 |
| Kotomtsev, VV | 1 |
| Doronin, AI | 1 |
| Sabadash, EV | 1 |
| Jang, J | 1 |
| Stella, A | 1 |
| Boudou, F | 1 |
| Levillain, F | 1 |
| Darthuy, E | 1 |
| Vaubourgeix, J | 1 |
| Wang, C | 1 |
| Bardou, F | 1 |
| Puzo, G | 1 |
| Gilleron, M | 1 |
| Burlet-Schiltz, O | 1 |
| Monsarrat, B | 1 |
| Brodin, P | 1 |
| Gicquel, B | 1 |
| Neyrolles, O | 1 |
| Miao, R | 1 |
| Li, J | 1 |
| Sun, Z | 1 |
| Xu, F | 1 |
| Shen, H | 1 |
| Bai, G | 1 |
| Schaak, DD | 1 |
| Smith, EA | 1 |
| McDonough, KA | 1 |
| Pilli, M | 1 |
| Arko-Mensah, J | 1 |
| Ponpuak, M | 1 |
| Roberts, E | 1 |
| Master, S | 1 |
| Mandell, MA | 1 |
| Dupont, N | 1 |
| Ornatowski, W | 1 |
| Jiang, S | 1 |
| Bradfute, SB | 1 |
| Bruun, JA | 1 |
| Hansen, TE | 1 |
| Johansen, T | 1 |
| Deretic, V | 1 |
| Rosado, LA | 1 |
| Caceres, RA | 1 |
| de Azevedo, WF | 1 |
| Basso, LA | 1 |
| Santos, DS | 1 |
1 review available for serine and Tuberculosis
| Article | Year |
|---|---|
Meta-analysis on the association of TIRAP S180L variant and tuberculosis susceptibility.
Topics: Black People; Case-Control Studies; Confidence Intervals; Female; Genetic Predisposition to Disease; | 2011 |
11 other studies available for serine and Tuberculosis
| Article | Year |
|---|---|
Identification of covalent inhibitors that disrupt M. tuberculosis growth by targeting multiple serine hydrolases involved in lipid metabolism.
Topics: Humans; Hydrolases; Lipid Metabolism; Mycobacterium tuberculosis; Serine; Tuberculosis | 2022 |
Heterologous production of the D-cycloserine intermediate O-acetyl-L-serine in a human type II pulmonary cell model.
Topics: Acetyl Coenzyme A; Anti-Bacterial Agents; COVID-19; Cycloserine; Humans; Serine; Tuberculosis | 2023 |
Mycobacterial Mutagenesis and Drug Resistance Are Controlled by Phosphorylation- and Cardiolipin-Mediated Inhibition of the RecA Coprotease.
Topics: Adenosine Triphosphatases; Cardiolipins; DNA Damage; Drug Resistance, Bacterial; Humans; Mutagenesis | 2018 |
Serine 83 in DosR, a response regulator from Mycobacterium tuberculosis, promotes its transition from an activated, phosphorylated state to an inactive, unphosphorylated state.
Topics: Bacterial Proteins; DNA-Binding Proteins; Gene Expression Regulation, Bacterial; Humans; Models, Mol | 2014 |
The Mycobacterium tuberculosis transcriptional repressor EthR is negatively regulated by Serine/Threonine phosphorylation.
Topics: Amino Acid Sequence; Antitubercular Agents; Bacterial Proteins; Ethionamide; Humans; Molecular Seque | 2014 |
Uncovering the Serine Hydrolytic Landscape of Mycobacterium tuberculosis.
Topics: Antitubercular Agents; Bacterial Proteins; Hydrolases; Hydrolysis; Mycobacterium; Mycobacterium smeg | 2016 |
Antioxidant and Antimutagenic Metabolites in Animals with Opposite Sensitivity to Tuberculosis Mycobacteria and Mutagenic Xenobiotics.
Topics: Animals; Disease Susceptibility; Ethanolamine; Ethanolamines; Glutathione; Guinea Pigs; Liver; Methi | 2016 |
Functional characterization of the Mycobacterium tuberculosis serine/threonine kinase PknJ.
Topics: Amino Acid Sequence; Animals; Dimerization; Mice; Molecular Sequence Data; Mycobacterium tuberculosi | 2010 |
Dysregulation of serine biosynthesis contributes to the growth defect of a Mycobacterium tuberculosis crp mutant.
Topics: Animals; Bacterial Proteins; Base Sequence; Binding Sites; Cell Line; Cyclic AMP Receptor Protein; G | 2011 |
TBK-1 promotes autophagy-mediated antimicrobial defense by controlling autophagosome maturation.
Topics: Adaptor Proteins, Signal Transducing; Animals; Autophagy; Autophagy-Related Protein 7; Green Fluores | 2012 |
Role of Serine140 in the mode of action of Mycobacterium tuberculosis β-ketoacyl-ACP Reductase (MabA).
Topics: 3-Oxoacyl-(Acyl-Carrier-Protein) Reductase; Alcohol Oxidoreductases; Amino Acid Substitution; Bacter | 2012 |