serine has been researched along with Thrombocytopenia in 4 studies
Serine: A non-essential amino acid occurring in natural form as the L-isomer. It is synthesized from GLYCINE or THREONINE. It is involved in the biosynthesis of PURINES; PYRIMIDINES; and other amino acids.
serine : An alpha-amino acid that is alanine substituted at position 3 by a hydroxy group.
Thrombocytopenia: A subnormal level of BLOOD PLATELETS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The pharmacological mechanisms underlying the adverse effects of linezolid on thrombocytopenia have not been conclusively determined." | 8.12 | Identifying and Targeting Prediction of the PI3K-AKT Signaling Pathway in Drug-Induced Thrombocytopenia in Infected Patients Receiving Linezolid Therapy: A Network Pharmacology-Based Analysis. ( Chen, H; Feng, S; Li, Y; Liu, C; Wang, H; Xie, J; Zheng, X, 2022) |
| "The pharmacological mechanisms underlying the adverse effects of linezolid on thrombocytopenia have not been conclusively determined." | 4.12 | Identifying and Targeting Prediction of the PI3K-AKT Signaling Pathway in Drug-Induced Thrombocytopenia in Infected Patients Receiving Linezolid Therapy: A Network Pharmacology-Based Analysis. ( Chen, H; Feng, S; Li, Y; Liu, C; Wang, H; Xie, J; Zheng, X, 2022) |
| " Glycine 41, invariant throughout eukaryotes, is substituted by serine in a family with autosomal dominant thrombocytopenia caused by dysregulated platelet formation." | 3.74 | A mutation of human cytochrome c enhances the intrinsic apoptotic pathway but causes only thrombocytopenia. ( Bockett, NA; Capron, C; Cheesman, EJ; Cheong, PL; Coker, MS; Cramer Bordé, EM; da Silva Tatley, FM; Davies, SM; Fagerlund, RD; Fichelson, S; Holyoake, AJ; Hughes, G; Ledgerwood, EC; Lo, A; Ludgate, MW; Morison, IM; Pippig, DA; Smith, MP; Weeks, RJ; Wilbanks, SM, 2008) |
| "Platelet-type von Willebrand disease (plt-VWD) is a congenital bleeding disorder characterized by gain-of-function mutations of GPIbalpha." | 1.32 | Identification of a novel point mutation in platelet glycoprotein Ibalpha, Gly to Ser at residue 233, in a Japanese family with platelet-type von Willebrand disease. ( Ikeda, Y; Matsubara, Y; Murata, M; Sugita, K, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Xie, J | 1 |
| Chen, H | 1 |
| Li, Y | 1 |
| Liu, C | 1 |
| Zheng, X | 1 |
| Feng, S | 1 |
| Wang, H | 1 |
| Matsubara, Y | 1 |
| Murata, M | 1 |
| Sugita, K | 1 |
| Ikeda, Y | 1 |
| Morison, IM | 1 |
| Cramer Bordé, EM | 1 |
| Cheesman, EJ | 1 |
| Cheong, PL | 1 |
| Holyoake, AJ | 1 |
| Fichelson, S | 1 |
| Weeks, RJ | 1 |
| Lo, A | 1 |
| Davies, SM | 1 |
| Wilbanks, SM | 1 |
| Fagerlund, RD | 1 |
| Ludgate, MW | 1 |
| da Silva Tatley, FM | 1 |
| Coker, MS | 1 |
| Bockett, NA | 1 |
| Hughes, G | 1 |
| Pippig, DA | 1 |
| Smith, MP | 1 |
| Capron, C | 1 |
| Ledgerwood, EC | 1 |
| Kawatsu, M | 1 |
| Yamashita, T | 1 |
| Ishizuka, M | 1 |
| Takeuchi, T | 1 |
4 other studies available for serine and Thrombocytopenia
| Article | Year |
|---|---|
Identifying and Targeting Prediction of the PI3K-AKT Signaling Pathway in Drug-Induced Thrombocytopenia in Infected Patients Receiving Linezolid Therapy: A Network Pharmacology-Based Analysis.
Topics: ErbB Receptors; Humans; Interleukin-6; Linezolid; Network Pharmacology; Phosphatidylinositol 3-Kinas | 2022 |
Identification of a novel point mutation in platelet glycoprotein Ibalpha, Gly to Ser at residue 233, in a Japanese family with platelet-type von Willebrand disease.
Topics: Bleeding Time; Blood Platelets; Blood Proteins; Cell Line; Child, Preschool; Dose-Response Relations | 2003 |
A mutation of human cytochrome c enhances the intrinsic apoptotic pathway but causes only thrombocytopenia.
Topics: Apoptosis; Apoptotic Protease-Activating Factor 1; Cytochromes c; Female; Genetic Linkage; Humans; M | 2008 |
Effect of conagenin on thrombocytopenia induced by antitumor agents in mice.
Topics: Animals; Antineoplastic Agents; Bone Marrow; Cells, Cultured; Fluorouracil; Interleukin-2; Interleuk | 1994 |