Page last updated: 2024-11-08

serine and Stroke

serine has been researched along with Stroke in 7 studies

Serine: A non-essential amino acid occurring in natural form as the L-isomer. It is synthesized from GLYCINE or THREONINE. It is involved in the biosynthesis of PURINES; PYRIMIDINES; and other amino acids.
serine : An alpha-amino acid that is alanine substituted at position 3 by a hydroxy group.

Stroke: A group of pathological conditions characterized by sudden, non-convulsive loss of neurological function due to BRAIN ISCHEMIA or INTRACRANIAL HEMORRHAGES. Stroke is classified by the type of tissue NECROSIS, such as the anatomic location, vasculature involved, etiology, age of the affected individual, and hemorrhagic vs. non-hemorrhagic nature. (From Adams et al., Principles of Neurology, 6th ed, pp777-810)

Research Excerpts

ExcerptRelevanceReference
" We show that modulation of the eNOS serine 1179 (S1179) phosphorylation site affects vascular reactivity and determines stroke size in vivo."3.74The phosphorylation state of eNOS modulates vascular reactivity and outcome of cerebral ischemia in vivo. ( Atochin, DN; Ayata, C; Critchlow, JD; Dantas, AP; Huang, PL; Liu, VW; Looft-Wilson, R; Michel, T; Moskowitz, MA; Murata, T; Salomone, S; Sessa, WC; Shin, HK; Wang, A, 2007)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (57.14)29.6817
2010's2 (28.57)24.3611
2020's1 (14.29)2.80

Authors

AuthorsStudies
Pegadraju, H1
Abby Thomas, J1
Kumar, R1
Lie, ME1
Gowing, EK1
Johansen, NB1
Dalby, NO1
Thiesen, L1
Wellendorph, P1
Clarkson, AN1
Liu, P2
Li, R1
Antonov, AA1
Wang, L2
Li, W1
Hua, Y1
Guo, H1
Chen, L1
Tian, Y1
Xu, F1
Zhang, Z1
Zhu, Y1
Huang, Y1
Stanton, PK1
Potter, PE1
Aguilar, J1
Decandia, M1
Moskal, JR1
Atochin, DN1
Wang, A1
Liu, VW1
Critchlow, JD1
Dantas, AP1
Looft-Wilson, R1
Murata, T1
Salomone, S1
Shin, HK1
Ayata, C1
Moskowitz, MA1
Michel, T1
Sessa, WC1
Huang, PL1
Hall, S1
Talmud, PJ1
Cook, DG1
Wicks, PD1
Rothwell, MJ1
Strazzullo, P1
Sagnella, GA1
Cappuccio, FP1
Van Aken, H1
Bode, C1
Darius, H1
Diehm, C1
Encke, A1
Gulba, DC1
Haas, S1
Hacke, W1
Puhl, W1
Quante, M1
Riess, H1
Scharf, R1
Schellong, S1
Schrör, T1
Schulte, KL1
Tebbe, U1

Reviews

2 reviews available for serine and Stroke

ArticleYear
Mechanistic and therapeutic role of Drp1 in the pathogenesis of stroke.
    Gene, 2023, Mar-01, Volume: 855

    Topics: Aged; Apoptosis; Dynamins; Humans; Mitochondria; Mitochondrial Proteins; Phosphorylation; Serine; St

2023
Anticoagulation: the present and future.
    Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis, 2001, Volume: 7, Issue:3

    Topics: Administration, Oral; Amino Acid Chloromethyl Ketones; Anticoagulants; Arginine; Azetidines; Benzyla

2001

Other Studies

5 other studies available for serine and Stroke

ArticleYear
GAT3 selective substrate l-isoserine upregulates GAT3 expression and increases functional recovery after a focal ischemic stroke in mice.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2019, Volume: 39, Issue:1

    Topics: Animals; Brain Ischemia; Dose-Response Relationship, Drug; GABA Plasma Membrane Transport Proteins;

2019
Discovery of Metabolite Biomarkers for Acute Ischemic Stroke Progression.
    Journal of proteome research, 2017, 02-03, Volume: 16, Issue:2

    Topics: Aged; Betaine; Biomarkers; Disease Progression; Early Diagnosis; Female; Humans; Isoleucine; Male; M

2017
Neuroprotection by a novel NMDAR functional glycine site partial agonist, GLYX-13.
    Neuroreport, 2009, Aug-26, Volume: 20, Issue:13

    Topics: Animals; Brain Ischemia; Carotid Artery Diseases; Cell Death; Cell Hypoxia; Female; Gerbillinae; Glu

2009
The phosphorylation state of eNOS modulates vascular reactivity and outcome of cerebral ischemia in vivo.
    The Journal of clinical investigation, 2007, Volume: 117, Issue:7

    Topics: Alanine; Animals; Aspartic Acid; Brain Ischemia; Cerebral Arteries; Disease Models, Animal; Gene Exp

2007
Frequency and allelic association of common variants in the lipoprotein lipase gene in different ethnic groups: the Wandsworth Heart and Stroke Study.
    Genetic epidemiology, 2000, Volume: 18, Issue:3

    Topics: Adult; Alleles; Asian People; Black People; Deoxyribonuclease HindIII; Female; Gene Frequency; Genet

2000