serine has been researched along with Stomach Neoplasms in 29 studies
Serine: A non-essential amino acid occurring in natural form as the L-isomer. It is synthesized from GLYCINE or THREONINE. It is involved in the biosynthesis of PURINES; PYRIMIDINES; and other amino acids.
serine : An alpha-amino acid that is alanine substituted at position 3 by a hydroxy group.
Stomach Neoplasms: Tumors or cancer of the STOMACH.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Further, the SGC7901 cell model of gastric cancer was employed to validate the efficacy and key targets of the herb pair." | 1.91 | [Mechanism of Astragali Radix-Curcumae Rhizoma in treating gastric cancer based on network pharmacology and experimental verification]. ( Gu, RX; Tan, XY; Tao, J; Zhang, Y, 2023) |
| "Gastric cancer is one of the malignant tumors in the world." | 1.72 | CORO1C, a novel PAK4 binding protein, recruits phospho-PAK4 at serine 99 to the leading edge and promotes the migration of gastric cancer cells. ( Chen, M; Li, F; Li, J; Li, X; Yuan, Y, 2022) |
| "The regulatory mechanisms underlying gastric cancer cell proliferation are largely unclear." | 1.51 | SCF ( Chen, M; Chen, R; Cui, B; Gao, D; Huang, J; Kuai, X; Li, J; Li, L; Qin, J; Wang, K; Wang, Z; Wei, W; Zhang, Y; Zhou, H; Zhu, H, 2019) |
| "In this study, FBXO31 inhibits gastric cancer progression by suppressing the epithelial-mesenchymal transition (EMT)." | 1.48 | FBXO31 Suppresses Gastric Cancer EMT by Targeting Snail1 for Proteasomal Degradation. ( Jia, J; Liu, Z; Ma, C; Xu, X; Yang, F; Zou, S, 2018) |
| "However, the role of Gln in gastric cancer (GC) metabolism is unknown and Gln-targeted therapy against GC remains scarce." | 1.48 | Targeting of glutamine transporter ASCT2 and glutamine synthetase suppresses gastric cancer cell growth. ( Chen, W; Huang, J; Huang, Q; Lin, X; Wang, J; Xu, J; Ye, J; Zhong, W, 2018) |
| "Further, histopathologically negative resection margins in several cancers have been associated with better prognosis of the disease." | 1.43 | p38-MAPK/MSK1-mediated overexpression of histone H3 serine 10 phosphorylation defines distance-dependent prognostic value of negative resection margin in gastric cancer. ( Amnekar, R; Barreto, SG; Gupta, S; Khade, B; Khan, SA; Ramadwar, M; Shrikhande, SV, 2016) |
| "However, how to regulate cortactin in gastric cancer remains largely unknown." | 1.40 | FBXL5 targets cortactin for ubiquitination-mediated destruction to regulate gastric cancer cell migration. ( Cen, G; Ding, HH; Liu, B; Wu, WD, 2014) |
| "DIF-1 inhibited proliferation of gastric cancer cells." | 1.32 | Differentiation-inducing factor-1 (DIF-1) inhibits STAT3 activity involved in gastric cancer cell proliferation via MEK-ERK-dependent pathway. ( Chiba, T; Izumi, Y; Kanai, M; Kanda, N; Konda, Y; Kubohara, Y; Nakajima, T; Nanakin, A, 2003) |
| "To investigate its association with stomach cancer risk and possible interactions with environmental factors, we conducted a case-control study of 101 stomach cancer cases and 198 controls using PCR-single-strand conformation polymorphism and a questionnaire approach." | 1.31 | hOGG1 Ser(326)Cys polymorphism and modification by environmental factors of stomach cancer risk in Chinese. ( Ding, JH; Gao, CM; Hu, X; Li, ZY; Liu, YT; Sugimura, H; Tajima, K; Takezaki, T; Wang, JD; Wu, JZ; Xu, TL, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (13.79) | 18.7374 |
| 1990's | 2 (6.90) | 18.2507 |
| 2000's | 6 (20.69) | 29.6817 |
| 2010's | 13 (44.83) | 24.3611 |
| 2020's | 4 (13.79) | 2.80 |
| Authors | Studies |
|---|---|
| Li, X | 3 |
| Chen, M | 2 |
| Yuan, Y | 1 |
| Li, J | 5 |
| Li, F | 3 |
| Chen, L | 3 |
| Chen, D | 3 |
| He, L | 3 |
| Chen, T | 3 |
| Song, D | 3 |
| Shan, S | 3 |
| Wang, J | 5 |
| Lu, X | 3 |
| Lu, B | 3 |
| Tan, XY | 1 |
| Tao, J | 1 |
| Zhang, Y | 2 |
| Gu, RX | 1 |
| Shi, Q | 1 |
| Ni, X | 1 |
| Lei, M | 1 |
| Xia, Q | 1 |
| Dong, Y | 1 |
| Zhang, Q | 2 |
| Wang, W | 2 |
| Zeng, S | 1 |
| Xie, X | 1 |
| Xiao, YF | 1 |
| Tang, B | 1 |
| Hu, CJ | 1 |
| Wang, SM | 1 |
| Wu, YY | 1 |
| Dong, H | 1 |
| Li, BS | 1 |
| Yang, SM | 1 |
| Zou, S | 1 |
| Ma, C | 1 |
| Yang, F | 1 |
| Xu, X | 1 |
| Jia, J | 1 |
| Liu, Z | 1 |
| Ye, J | 1 |
| Huang, Q | 1 |
| Xu, J | 2 |
| Huang, J | 2 |
| Zhong, W | 1 |
| Chen, W | 1 |
| Lin, X | 2 |
| Kuai, X | 1 |
| Li, L | 1 |
| Chen, R | 1 |
| Wang, K | 1 |
| Cui, B | 1 |
| Zhu, H | 1 |
| Zhou, H | 1 |
| Qin, J | 1 |
| Wang, Z | 2 |
| Wei, W | 1 |
| Gao, D | 1 |
| Guo, Q | 1 |
| Su, N | 1 |
| Zhang, J | 1 |
| Miao, Z | 2 |
| Wang, G | 2 |
| Cheng, M | 1 |
| Xu, H | 3 |
| Cao, L | 2 |
| Cen, G | 1 |
| Ding, HH | 1 |
| Liu, B | 1 |
| Wu, WD | 1 |
| Song, Y | 1 |
| Liu, T | 1 |
| Wang, C | 1 |
| Liu, F | 1 |
| Cai, X | 2 |
| Bian, Y | 1 |
| Zhao, W | 1 |
| Cao, H | 1 |
| Zhang, Z | 1 |
| Zhang, N | 1 |
| Chen, X | 1 |
| Jiang, M | 1 |
| Qiu, Z | 1 |
| Zhang, S | 1 |
| Fan, X | 1 |
| Xu, B | 1 |
| Zhou, J | 1 |
| Zhang, X | 1 |
| Chu, Y | 1 |
| Liang, J | 1 |
| Horvath, T | 1 |
| Yang, X | 1 |
| Wu, K | 1 |
| Nie, Y | 1 |
| Fan, D | 1 |
| Khan, SA | 1 |
| Amnekar, R | 1 |
| Khade, B | 1 |
| Barreto, SG | 1 |
| Ramadwar, M | 1 |
| Shrikhande, SV | 1 |
| Gupta, S | 1 |
| Zheng, HC | 1 |
| Xu, XY | 1 |
| Xia, P | 1 |
| Yu, M | 1 |
| Takahashi, H | 1 |
| Takano, Y | 1 |
| Busch, T | 1 |
| Armacki, M | 1 |
| Eiseler, T | 1 |
| Joodi, G | 1 |
| Temme, C | 1 |
| Jansen, J | 1 |
| von Wichert, G | 1 |
| Omary, MB | 2 |
| Spatz, J | 1 |
| Seufferlein, T | 1 |
| Kanai, M | 1 |
| Konda, Y | 1 |
| Nakajima, T | 1 |
| Izumi, Y | 1 |
| Kanda, N | 1 |
| Nanakin, A | 1 |
| Kubohara, Y | 1 |
| Chiba, T | 1 |
| Tao, GZ | 1 |
| Nakamichi, I | 1 |
| Ku, NO | 1 |
| Frolkis, M | 1 |
| Gong, X | 1 |
| Zhu, W | 1 |
| Pytela, R | 1 |
| Pühringer-Oppermann, F | 1 |
| Stahl, M | 1 |
| Keller, G | 1 |
| Sarbia, M | 1 |
| Kang, B | 1 |
| Guo, RF | 1 |
| Tan, XH | 1 |
| Zhao, M | 1 |
| Tang, ZB | 1 |
| Lu, YY | 1 |
| Gandino, L | 2 |
| Longati, P | 1 |
| Medico, E | 1 |
| Prat, M | 1 |
| Comoglio, PM | 2 |
| Takezaki, T | 1 |
| Gao, CM | 1 |
| Wu, JZ | 1 |
| Li, ZY | 1 |
| Wang, JD | 1 |
| Ding, JH | 1 |
| Liu, YT | 1 |
| Hu, X | 1 |
| Xu, TL | 1 |
| Tajima, K | 1 |
| Sugimura, H | 1 |
| Hori, K | 1 |
| Saito, S | 1 |
| Kubota, K | 1 |
| Kalinovskiĭ, VP | 1 |
| Parshin, AN | 1 |
| Di Renzo, MF | 1 |
| Giordano, S | 1 |
| Bussolino, F | 1 |
| Nishimura, M | 1 |
| Nakada, H | 1 |
| Kawamura, I | 1 |
| Mizota, T | 1 |
| Shimomura, K | 1 |
| Nakahara, K | 1 |
| Goto, T | 1 |
| Yamaguchi, I | 1 |
| Okuhara, M | 1 |
| Schrager, J | 1 |
| Oates, MD | 1 |
| Spellman, CM | 1 |
| Fottrell, PF | 1 |
29 other studies available for serine and Stomach Neoplasms
| Article | Year |
|---|---|
CORO1C, a novel PAK4 binding protein, recruits phospho-PAK4 at serine 99 to the leading edge and promotes the migration of gastric cancer cells.
Topics: Carrier Proteins; Cell Line, Tumor; Cell Movement; Humans; p21-Activated Kinases; Phosphorylation; S | 2022 |
Ciclopirox drives growth arrest and autophagic cell death through STAT3 in gastric cancer cells.
Topics: Autophagic Cell Death; Ciclopirox; Humans; Phosphorylation; Serine; STAT3 Transcription Factor; Stom | 2022 |
Ciclopirox drives growth arrest and autophagic cell death through STAT3 in gastric cancer cells.
Topics: Autophagic Cell Death; Ciclopirox; Humans; Phosphorylation; Serine; STAT3 Transcription Factor; Stom | 2022 |
Ciclopirox drives growth arrest and autophagic cell death through STAT3 in gastric cancer cells.
Topics: Autophagic Cell Death; Ciclopirox; Humans; Phosphorylation; Serine; STAT3 Transcription Factor; Stom | 2022 |
Ciclopirox drives growth arrest and autophagic cell death through STAT3 in gastric cancer cells.
Topics: Autophagic Cell Death; Ciclopirox; Humans; Phosphorylation; Serine; STAT3 Transcription Factor; Stom | 2022 |
[Mechanism of Astragali Radix-Curcumae Rhizoma in treating gastric cancer based on network pharmacology and experimental verification].
Topics: Adenosine Triphosphate; Drugs, Chinese Herbal; ErbB Receptors; Humans; Molecular Docking Simulation; | 2023 |
Phosphorylation of islet-1 serine 269 by CDK1 increases its transcriptional activity and promotes cell proliferation in gastric cancer.
Topics: Adult; Aged; Amino Acid Sequence; Animals; CDC2 Protein Kinase; Female; Humans; LIM-Homeodomain Prot | 2021 |
Long noncoding RNA LINC00675 enhances phosphorylation of vimentin on Ser83 to suppress gastric cancer progression.
Topics: Adult; Aged; Animals; Cell Movement; Disease Progression; Female; Genes, Tumor Suppressor; Humans; M | 2018 |
FBXO31 Suppresses Gastric Cancer EMT by Targeting Snail1 for Proteasomal Degradation.
Topics: Animals; Cell Line, Tumor; Epithelial-Mesenchymal Transition; F-Box Proteins; Humans; Mice; Neoplasm | 2018 |
Targeting of glutamine transporter ASCT2 and glutamine synthetase suppresses gastric cancer cell growth.
Topics: Amino Acid Transport System ASC; Animals; Antineoplastic Combined Chemotherapy Protocols; Benzene; C | 2018 |
SCF
Topics: Animals; Carrier Proteins; Cell Proliferation; DNA-Binding Proteins; F-Box-WD Repeat-Containing Prot | 2019 |
PAK4 kinase-mediated SCG10 phosphorylation involved in gastric cancer metastasis.
Topics: Animals; cdc42 GTP-Binding Protein; Cell Line; Cell Line, Tumor; Cell Movement; Female; HEK293 Cells | 2014 |
FBXL5 targets cortactin for ubiquitination-mediated destruction to regulate gastric cancer cell migration.
Topics: Binding Sites; Blotting, Western; Cell Line, Tumor; Cell Movement; Cortactin; Extracellular Signal-R | 2014 |
PAK1-mediated MORC2 phosphorylation promotes gastric tumorigenesis.
Topics: Animals; Carcinogenesis; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cell Transformation, Neop | 2015 |
Elevated Rictor expression is associated with tumor progression and poor prognosis in patients with gastric cancer.
Topics: Biomarkers, Tumor; Carrier Proteins; Disease Progression; Female; Humans; Male; Middle Aged; Prognos | 2015 |
Potential role of O-GlcNAcylation and involvement of PI3K/Akt1 pathway in the expression of oncogenic phenotypes of gastric cancer cells in vitro.
Topics: Acetylglucosamine; beta-N-Acetylhexosaminidases; Cell Line, Tumor; Cell Movement; Cell Proliferation | 2016 |
Elevated O-GlcNAcylation promotes gastric cancer cells proliferation by modulating cell cycle related proteins and ERK 1/2 signaling.
Topics: Acetylglucosamine; Animals; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cyclin D1; Cyclin-Depe | 2016 |
p38-MAPK/MSK1-mediated overexpression of histone H3 serine 10 phosphorylation defines distance-dependent prognostic value of negative resection margin in gastric cancer.
Topics: Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Histones; Humans; Male; MAP Kin | 2016 |
Involvement of inactive GSK3beta overexpression in tumorigenesis and progression of gastric carcinomas.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Biomarkers, Tumor; Cell Line, Tumor; Disease Progres | 2010 |
Keratin 8 phosphorylation regulates keratin reorganization and migration of epithelial tumor cells.
Topics: Cell Line, Tumor; Cell Movement; Cytoskeleton; Epithelial Cells; Extracellular Signal-Regulated MAP | 2012 |
Differentiation-inducing factor-1 (DIF-1) inhibits STAT3 activity involved in gastric cancer cell proliferation via MEK-ERK-dependent pathway.
Topics: Base Sequence; Caenorhabditis elegans Proteins; Carrier Proteins; Cell Division; DNA Primers; DNA-Bi | 2003 |
Bispecific and human disease-related anti-keratin rabbit monoclonal antibodies.
Topics: Animals; Antibodies, Bispecific; Antibodies, Monoclonal; Brain; Brain Chemistry; Cell Line; Colonic | 2006 |
Lack of prognostic impact of p53 gene mutation and p53 phosphorylation at serine 15 in multimodally treated adenocarcinomas of the gastroesophageal junction.
Topics: Adenocarcinoma; Base Sequence; Chromatography, High Pressure Liquid; Clinical Trials, Phase III as T | 2006 |
Expression status of ataxia-telangiectasia-mutated gene correlated with prognosis in advanced gastric cancer.
Topics: Adult; Aged; Aged, 80 and over; Ataxia Telangiectasia Mutated Proteins; Base Sequence; Biomarkers, T | 2008 |
Phosphorylation of serine 985 negatively regulates the hepatocyte growth factor receptor kinase.
Topics: Amino Acid Sequence; Calcimycin; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Consensus | 1994 |
hOGG1 Ser(326)Cys polymorphism and modification by environmental factors of stomach cancer risk in Chinese.
Topics: Adult; Aged; Aged, 80 and over; Alcohol Drinking; Alleles; China; Cysteine; DNA-Formamidopyrimidine | 2002 |
A novel combretastatin A-4 derivative, AC7700, strongly stanches tumour blood flow and inhibits growth of tumours developing in various tissues and organs.
Topics: Animals; Antineoplastic Agents, Phytogenic; Carcinoma; Drug Screening Assays, Antitumor; Heart Neopl | 2002 |
[Biosynthesis of soluble proteins and pepsinogen of the mucus membrane and cancer of the stomach in man].
Topics: Gastric Mucosa; Humans; Pepsinogens; Protein Biosynthesis; Serine; Stomach Neoplasms; Tyrosine | 1975 |
Protein kinase-c activation inhibits tyrosine phosphorylation of the c-met protein.
Topics: Animals; Diglycerides; Gene Amplification; Gene Expression; Humans; Phorbol Esters; Phosphorylation; | 1990 |
A new antitumor antibiotic, FR900840. III. Antitumor activity against experimental tumors.
Topics: Adenocarcinoma; Animals; Antibiotics, Antineoplastic; Carcinoma, Small Cell; Carcinoma, Squamous Cel | 1989 |
A comparative study of the major glycoprotein isolated from normal and neoplastic gastric mucosa.
Topics: Agglutination Tests; Amino Acids; Blood Group Antigens; Chromatography; Chromatography, Gel; Fucose; | 1973 |
Similarities between pyruvate kinase from human placenta and tumours.
Topics: Adenosine Triphosphate; Alanine; Carcinoma; Chromatography, Gel; Chromatography, Ion Exchange; Elect | 1973 |