serine has been researched along with Skin Neoplasms in 27 studies
Serine: A non-essential amino acid occurring in natural form as the L-isomer. It is synthesized from GLYCINE or THREONINE. It is involved in the biosynthesis of PURINES; PYRIMIDINES; and other amino acids.
serine : An alpha-amino acid that is alanine substituted at position 3 by a hydroxy group.
Skin Neoplasms: Tumors or cancer of the SKIN.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Copy number gain of the D-3-phosphoglycerate dehydrogenase (PHGDH) gene, which encodes the first enzyme in serine biosynthesis, is found in some human cancers including a subset of melanomas." | 3.91 | Increased PHGDH expression promotes aberrant melanin accumulation. ( Bronson, RT; Fiske, BP; Lau, AN; Mattaini, KR; Sullivan, MR; Vander Heiden, MG, 2019) |
| "Two human skin cell lines: Hs 895." | 1.56 | Roles of N-methyl-D-aspartate receptors and D-amino acids in cancer cell viability. ( Alatrash, N; Armstrong, DW; Berthod, A; Du, S; MacDonnell, FM; Sung, YS; Wang, Y; Wey, M, 2020) |
| "During squamous cell carcinoma (SCC) invasion, there is a reduction in the number of HDs, which may facilitate dissemination." | 1.37 | Role of β4 integrin phosphorylation in human invasive squamous cell carcinoma: regulation of hemidesmosome stability modulates cell migration. ( Germain, E; Kashyap, T; Lyle, S; Rabinovitz, I; Roche, M, 2011) |
| "The putative metastasis suppressor genes, NME1(nm23-1) and NME2(nm23-2), were examined in a model system we developed to approximate the dissemination of melanoma from a primary skin tumor." | 1.29 | Differential expression and mutation of NME genes in autologous cultured human melanoma cells with different metastatic potentials. ( Backer, JM; Hamby, CV; Mendola, CE; Potla, L; Stafford, G, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (3.70) | 18.2507 |
| 2000's | 13 (48.15) | 29.6817 |
| 2010's | 10 (37.04) | 24.3611 |
| 2020's | 3 (11.11) | 2.80 |
| Authors | Studies |
|---|---|
| Lee, CJ | 1 |
| An, HJ | 1 |
| Kim, SM | 1 |
| Yoo, SM | 1 |
| Park, J | 1 |
| Lee, GE | 1 |
| Kim, WY | 1 |
| Kim, DJ | 1 |
| Kang, HC | 1 |
| Lee, JY | 1 |
| Lee, HS | 1 |
| Cho, SJ | 1 |
| Cho, YY | 2 |
| Najjar, S | 1 |
| Homan, S | 1 |
| Sheehan, C | 1 |
| Carlson, JA | 1 |
| Du, S | 1 |
| Sung, YS | 1 |
| Wey, M | 1 |
| Wang, Y | 1 |
| Alatrash, N | 1 |
| Berthod, A | 1 |
| MacDonnell, FM | 1 |
| Armstrong, DW | 1 |
| Kawamura, A | 1 |
| Kawamura, T | 1 |
| Riddell, M | 1 |
| Hikita, T | 1 |
| Yanagi, T | 1 |
| Umemura, H | 1 |
| Nakayama, M | 1 |
| Mattaini, KR | 1 |
| Sullivan, MR | 1 |
| Lau, AN | 1 |
| Fiske, BP | 1 |
| Bronson, RT | 1 |
| Vander Heiden, MG | 1 |
| Bernard, JJ | 1 |
| Lou, YR | 2 |
| Peng, QY | 2 |
| Li, T | 1 |
| Conney, AH | 2 |
| Lu, YP | 2 |
| Wang, Q | 1 |
| Beaumont, KA | 1 |
| Otte, NJ | 1 |
| Font, J | 1 |
| Bailey, CG | 1 |
| van Geldermalsen, M | 1 |
| Sharp, DM | 1 |
| Tiffen, JC | 1 |
| Ryan, RM | 1 |
| Jormakka, M | 1 |
| Haass, NK | 1 |
| Rasko, JE | 1 |
| Holst, J | 1 |
| Schrama, D | 1 |
| Hesbacher, S | 1 |
| Angermeyer, S | 1 |
| Schlosser, A | 1 |
| Haferkamp, S | 1 |
| Aue, A | 1 |
| Adam, C | 1 |
| Weber, A | 1 |
| Schmidt, M | 1 |
| Houben, R | 1 |
| Lee, DE | 1 |
| Lee, KW | 1 |
| Song, NR | 1 |
| Seo, SK | 1 |
| Heo, YS | 1 |
| Kang, NJ | 1 |
| Bode, AM | 2 |
| Lee, HJ | 1 |
| Dong, Z | 2 |
| Nghiem, P | 1 |
| Bachelor, MA | 1 |
| Lu, Y | 1 |
| Owens, DM | 1 |
| Kashyap, T | 1 |
| Germain, E | 1 |
| Roche, M | 1 |
| Lyle, S | 1 |
| Rabinovitz, I | 1 |
| Lee, BR | 1 |
| Matsuo, Y | 1 |
| Cashikar, AG | 1 |
| Kamitani, T | 1 |
| Sun, P | 1 |
| Wang, XQ | 1 |
| Lopatka, K | 1 |
| Bangash, S | 1 |
| Paller, AS | 1 |
| Leis, H | 1 |
| Segrelles, C | 1 |
| Ruiz, S | 1 |
| Santos, M | 1 |
| Paramio, JM | 1 |
| Melnikova, VO | 1 |
| Santamaria, AB | 1 |
| Bolshakov, SV | 1 |
| Ananthaswamy, HN | 1 |
| Matsumoto, M | 1 |
| Furihata, M | 1 |
| Kurabayashi, A | 1 |
| Ohtsuki, Y | 1 |
| Hoogervorst, EM | 1 |
| Bruins, W | 1 |
| Zwart, E | 1 |
| van Oostrom, CT | 1 |
| van den Aardweg, GJ | 1 |
| Beems, RB | 1 |
| van den Berg, J | 1 |
| Jacks, T | 1 |
| van Steeg, H | 1 |
| de Vries, A | 1 |
| Roesch, A | 1 |
| Becker, B | 1 |
| Schneider-Brachert, W | 1 |
| Hagen, I | 1 |
| Landthaler, M | 1 |
| Vogt, T | 1 |
| Tatsumi, Y | 1 |
| He, Z | 1 |
| Mizuno, H | 1 |
| Seok Choi, H | 1 |
| Vernez, M | 1 |
| Hutter, P | 1 |
| Monnerat, C | 1 |
| Halkic, N | 1 |
| Gugerli, O | 1 |
| Bouzourene, H | 1 |
| Sánchez-Laorden, BL | 1 |
| Jiménez-Cervantes, C | 1 |
| García-Borrón, JC | 1 |
| Mo, JS | 1 |
| Kim, MY | 1 |
| Han, SO | 1 |
| Kim, IS | 1 |
| Ann, EJ | 1 |
| Lee, KS | 1 |
| Seo, MS | 1 |
| Kim, JY | 1 |
| Lee, SC | 1 |
| Park, JW | 1 |
| Choi, EJ | 1 |
| Seong, JY | 1 |
| Joe, CO | 1 |
| Faessler, R | 1 |
| Park, HS | 1 |
| Li, C | 1 |
| Chen, K | 1 |
| Liu, Z | 1 |
| Wang, LE | 1 |
| Gershenwald, JE | 1 |
| Lee, JE | 1 |
| Prieto, VG | 1 |
| Duvic, M | 1 |
| Grimm, EA | 1 |
| Wei, Q | 1 |
| Lewis, DA | 1 |
| Yi, Q | 1 |
| Travers, JB | 1 |
| Spandau, DF | 1 |
| Hamby, CV | 1 |
| Mendola, CE | 1 |
| Potla, L | 1 |
| Stafford, G | 1 |
| Backer, JM | 1 |
| Omholt, K | 1 |
| Platz, A | 1 |
| Ringborg, U | 1 |
| Hansson, J | 1 |
27 other studies available for serine and Skin Neoplasms
| Article | Year |
|---|---|
FBXW7-mediated stability regulation of signal transducer and activator of transcription 2 in melanoma formation.
Topics: Adult; Aged; Aged, 80 and over; Cell Line, Tumor; Cell Proliferation; F-Box-WD Repeat-Containing Pro | 2020 |
SERINE-910 Phosphorylated Focal Adhesion Kinase Expression Predicts Better Overall and Disease-free Survival in Melanoma.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Child; Child, Preschool; Cohort Studies; Disease-Free Su | 2020 |
Roles of N-methyl-D-aspartate receptors and D-amino acids in cancer cell viability.
Topics: Alanine; Amino Acids; Asparagine; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dizocilpine M | 2020 |
Regulation of programmed cell death ligand 1 expression by atypical protein kinase C lambda/iota in cutaneous angiosarcoma.
Topics: Aged; Aged, 80 and over; B7-H1 Antigen; Cell Line, Tumor; Female; Forkhead Box Protein O1; Gene Expr | 2019 |
Increased PHGDH expression promotes aberrant melanin accumulation.
Topics: Alleles; Animals; Cell Line; Doxycycline; Gene Expression; Hair Follicle; Humans; Melanins; Melanocy | 2019 |
Inverse relationship between p53 and phospho-Chk1 (Ser317) protein expression in UVB-induced skin tumors in SKH-1 mice.
Topics: Animals; Blotting, Western; Carcinoma, Squamous Cell; Checkpoint Kinase 1; Female; Mice; Mice, Hairl | 2014 |
Targeting glutamine transport to suppress melanoma cell growth.
Topics: Amino Acid Transport System ASC; Amino Acids, Cyclic; Benzyl Compounds; Biological Transport; Carrie | 2014 |
Serine 220 phosphorylation of the Merkel cell polyomavirus large T antigen crucially supports growth of Merkel cell carcinoma cells.
Topics: Active Transport, Cell Nucleus; Amino Acid Sequence; Antigens, Polyomavirus Transforming; Carcinoma, | 2016 |
7,3',4'-Trihydroxyisoflavone inhibits epidermal growth factor-induced proliferation and transformation of JB6 P+ mouse epidermal cells by suppressing cyclin-dependent kinases and phosphatidylinositol 3-kinase.
Topics: Animals; Anticarcinogenic Agents; Cell Line, Tumor; Cell Proliferation; Cyclin-Dependent Kinases; Ep | 2010 |
Caffeine decreases phospho-Chk1 (Ser317) and increases mitotic cells with cyclin B1 and caspase 3 in tumors from UVB-treated mice.
Topics: Administration, Topical; Animals; Apoptosis; Caffeine; Caspase 3; Central Nervous System Stimulants; | 2011 |
L-3-Phosphoserine phosphatase (PSPH) regulates cutaneous squamous cell carcinoma proliferation independent of L-serine biosynthesis.
Topics: Animals; Apoptosis; Base Sequence; Carcinoma, Squamous Cell; Cell Proliferation; Dimerization; DNA P | 2011 |
Role of β4 integrin phosphorylation in human invasive squamous cell carcinoma: regulation of hemidesmosome stability modulates cell migration.
Topics: Basement Membrane; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Movement; Drug Stability; Hemide | 2011 |
Role of Ser129 phosphorylation of α-synuclein in melanoma cells.
Topics: alpha-Synuclein; Amino Acid Sequence; Antibodies, Monoclonal; Cell Line, Tumor; Epitope Mapping; Hum | 2013 |
Ganglioside loss promotes survival primarily by activating integrin-linked kinase/Akt without phosphoinositide 3-OH kinase signaling.
Topics: Apoptosis; bcl-Associated Death Protein; Carcinoma, Squamous Cell; Carrier Proteins; Caspase 9; Casp | 2002 |
Expression, localization, and activity of glycogen synthase kinase 3beta during mouse skin tumorigenesis.
Topics: Animals; Blotting, Western; Cell Transformation, Neoplastic; Female; Glycogen Synthase Kinase 3; Gly | 2002 |
Mutant p53 is constitutively phosphorylated at Serine 15 in UV-induced mouse skin tumors: involvement of ERK1/2 MAP kinase.
Topics: Animals; Cell Nucleus; Female; Mice; Mice, Inbred C3H; Mitogen-Activated Protein Kinase 1; Mitogen-A | 2003 |
Phosphorylation state of tumor-suppressor gene p53 product overexpressed in skin tumors.
Topics: Bowen's Disease; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Gene Expression Regulation, Neopla | 2004 |
Lack of p53 Ser389 phosphorylation predisposes mice to develop 2-acetylaminofluorene-induced bladder tumors but not ionizing radiation-induced lymphomas.
Topics: 2-Acetylaminofluorene; Animals; Carcinogens; DNA Damage; Female; Genes, p53; Lymphoma; Male; Mice; M | 2005 |
Re-expression of the retinoblastoma-binding protein 2-homolog 1 reveals tumor-suppressive functions in highly metastatic melanoma cells.
Topics: Cell Division; Cell Line, Tumor; DNA-Binding Proteins; DNA, Complementary; G1 Phase; Gene Expression | 2006 |
Involvement of the paxillin pathway in JB6 Cl41 cell transformation.
Topics: Animals; Base Sequence; Cell Growth Processes; Cell Line; Cell Transformation, Neoplastic; Down-Regu | 2006 |
A case of Muir-Torre syndrome associated with mucinous hepatic cholangiocarcinoma and a novel germline mutation of the MSH2 gene.
Topics: Adenocarcinoma, Mucinous; Adenoma; Adult; Brain Neoplasms; Carcinoma; Cholangiocarcinoma; Colorectal | 2007 |
Regulation of human melanocortin 1 receptor signaling and trafficking by Thr-308 and Ser-316 and its alteration in variant alleles associated with red hair and skin cancer.
Topics: Amino Acid Sequence; Cell Line; Cyclic AMP; Genetic Variation; Hair Color; Humans; Models, Molecular | 2007 |
Integrin-linked kinase controls Notch1 signaling by down-regulation of protein stability through Fbw7 ubiquitin ligase.
Topics: Animals; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Cell Nucleus; Down-Regulation; Humans; Mel | 2007 |
Polymorphisms of TP53 Arg72Pro, but not p73 G4C14>A4TA4 and p21 Ser31Arg, contribute to risk of cutaneous melanoma.
Topics: Apoptosis; Arginine; Cyclin-Dependent Kinase Inhibitor p21; DNA Repair; DNA-Binding Proteins; Female | 2008 |
UVB-induced senescence in human keratinocytes requires a functional insulin-like growth factor-1 receptor and p53.
Topics: beta-Galactosidase; Caspase 3; Cells, Cultured; Cellular Senescence; Cyclin-Dependent Kinase Inhibit | 2008 |
Differential expression and mutation of NME genes in autologous cultured human melanoma cells with different metastatic potentials.
Topics: Amino Acid Sequence; Animals; Base Sequence; Cell Line; Clone Cells; DNA Primers; Gene Expression; G | 1995 |
Cytoplasmic and nuclear accumulation of beta-catenin is rarely caused by CTNNB1 exon 3 mutations in cutaneous malignant melanoma.
Topics: beta Catenin; Cell Nucleus; Codon; Cytoplasm; Cytoskeletal Proteins; DNA Mutational Analysis; Exons; | 2001 |