Page last updated: 2024-11-08

serine and Severe Combined Immunodeficiency

serine has been researched along with Severe Combined Immunodeficiency in 3 studies

Serine: A non-essential amino acid occurring in natural form as the L-isomer. It is synthesized from GLYCINE or THREONINE. It is involved in the biosynthesis of PURINES; PYRIMIDINES; and other amino acids.
serine : An alpha-amino acid that is alanine substituted at position 3 by a hydroxy group.

Severe Combined Immunodeficiency: Group of rare congenital disorders characterized by impairment of both humoral and cell-mediated immunity, leukopenia, and low or absent antibody levels. It is inherited as an X-linked or autosomal recessive defect. Mutations occurring in many different genes cause human Severe Combined Immunodeficiency (SCID).

Research Excerpts

ExcerptRelevanceReference
"Patients with severe combined immune deficiency (SCID) suffer from defective T-cell Ca2+ signaling."1.35Increased hydrophobicity at the N terminus/membrane interface impairs gating of the severe combined immunodeficiency-related ORAI1 mutant. ( Bergsmann, J; Carugo, O; Derler, I; Eshaghi, S; Fahrner, M; Frischauf, I; Muik, M; Romanin, C; Schindl, R, 2009)
"We used mice with severe combined immunodeficiency (SCID mice) to study the role of antibody in protection from amoebic liver abscess, and to identify protective antigens of E."1.29Antibodies to the serine rich Entamoeba histolytica protein (SREHP) prevent amoebic liver abscess in severe combined immunodeficient (SCID) mice. ( Cieslak, PR; Foster, L; Kunz-Jenkins, C; Stanley, SL; Zhang, T, 1994)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (66.67)18.2507
2000's1 (33.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Derler, I1
Fahrner, M1
Carugo, O1
Muik, M1
Bergsmann, J1
Schindl, R1
Frischauf, I1
Eshaghi, S1
Romanin, C1
Zhang, T1
Cieslak, PR1
Foster, L1
Kunz-Jenkins, C1
Stanley, SL1
Sasaki, Y1
Iseki, M1
Yamaguchi, S1
Kurosawa, Y1
Yamamoto, T1
Moriwaki, Y1
Kenri, T1
Sasaki, T1
Yamashita, R1

Other Studies

3 other studies available for serine and Severe Combined Immunodeficiency

ArticleYear
Increased hydrophobicity at the N terminus/membrane interface impairs gating of the severe combined immunodeficiency-related ORAI1 mutant.
    The Journal of biological chemistry, 2009, Jun-05, Volume: 284, Issue:23

    Topics: Amino Acid Substitution; Calcium Channels; Cell Line; Cell Membrane; Cloning, Molecular; Computation

2009
Antibodies to the serine rich Entamoeba histolytica protein (SREHP) prevent amoebic liver abscess in severe combined immunodeficient (SCID) mice.
    Parasite immunology, 1994, Volume: 16, Issue:5

    Topics: Animals; Antibodies, Protozoan; Antigens, Protozoan; Cell Adhesion; CHO Cells; Cricetinae; Entamoeba

1994
Direct evidence of autosomal recessive inheritance of Arg24 to termination codon in purine nucleoside phosphorylase gene in a family with a severe combined immunodeficiency patient.
    Human genetics, 1998, Volume: 103, Issue:1

    Topics: Amino Acid Sequence; Arginine; Base Sequence; Child, Preschool; Chromosome Mapping; Chromosomes, Hum

1998