serine has been researched along with Rhabdomyosarcoma, Alveolar in 2 studies
Serine: A non-essential amino acid occurring in natural form as the L-isomer. It is synthesized from GLYCINE or THREONINE. It is involved in the biosynthesis of PURINES; PYRIMIDINES; and other amino acids.
serine : An alpha-amino acid that is alanine substituted at position 3 by a hydroxy group.
Rhabdomyosarcoma, Alveolar: A form of RHABDOMYOSARCOMA occurring mainly in adolescents and young adults, affecting muscles of the extremities, trunk, orbital region, etc. It is extremely malignant, metastasizing widely at an early stage. Few cures have been achieved and the prognosis is poor. Alveolar refers to its microscopic appearance simulating the cells of the respiratory alveolus. (Holland et al., Cancer Medicine, 3d ed, p2188)
| Excerpt | Relevance | Reference |
|---|---|---|
| "ARMS is characterized by a t(2;13) chromosomal translocation resulting in the fusion of the 5' Pax3 sequences to the 3' FOXO1 sequences to encode the oncogenic fusion protein, Pax3-FOXO1." | 1.35 | Phosphorylation of serine 205 by the protein kinase CK2 persists on Pax3-FOXO1, but not Pax3, throughout early myogenic differentiation. ( Dietz, KN; Hollenbach, AD; Miller, PJ, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dietz, KN | 2 |
| Miller, PJ | 2 |
| Hollenbach, AD | 2 |
| Iyengar, AS | 1 |
| Loupe, JM | 1 |
2 other studies available for serine and Rhabdomyosarcoma, Alveolar
| Article | Year |
|---|---|
Phosphorylation of serine 205 by the protein kinase CK2 persists on Pax3-FOXO1, but not Pax3, throughout early myogenic differentiation.
Topics: Animals; Casein Kinase II; Cell Differentiation; Cell Line, Tumor; Cell Proliferation; Cells, Cultur | 2009 |
Identification of serines 201 and 209 as sites of Pax3 phosphorylation and the altered phosphorylation status of Pax3-FOXO1 during early myogenic differentiation.
Topics: Animals; Antibodies, Phospho-Specific; Casein Kinase II; Cell Line, Tumor; Child; Glycogen Synthase | 2011 |