serine has been researched along with Retinitis Pigmentosa in 10 studies
Serine: A non-essential amino acid occurring in natural form as the L-isomer. It is synthesized from GLYCINE or THREONINE. It is involved in the biosynthesis of PURINES; PYRIMIDINES; and other amino acids.
serine : An alpha-amino acid that is alanine substituted at position 3 by a hydroxy group.
Retinitis Pigmentosa: Hereditary, progressive degeneration of the retina due to death of ROD PHOTORECEPTORS initially and subsequent death of CONE PHOTORECEPTORS. It is characterized by deposition of pigment in the retina.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Transgenic mice expressing the rhodopsin mutant Pro347Ser (Serine 6) display retinal degeneration through apoptosis that is characteristic of the disease retinitis pigmentosa." | 3.69 | Altered cAMP levels in retinas from transgenic mice expressing a rhodopsin mutant. ( Dickerson, CD; Hao, Y; Osawa, S; Shi, W; Weiss, ER; Wong, F; Zhang, L, 1995) |
| "Night blindness was the first symptom to manifest, with onset between birth and age 16 years." | 1.32 | Phenotype of retinitis pigmentosa associated with the Ser50Thr mutation in the NRL gene. ( Bessant, DA; Bhattacharya, SS; Bird, AC; Fitzke, FW; Holder, GE; Payne, AM, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (30.00) | 18.7374 |
| 1990's | 3 (30.00) | 18.2507 |
| 2000's | 4 (40.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bessant, DA | 1 |
| Holder, GE | 1 |
| Fitzke, FW | 1 |
| Payne, AM | 1 |
| Bhattacharya, SS | 2 |
| Bird, AC | 1 |
| Tetreault, ML | 1 |
| Horrigan, DM | 1 |
| Kim, JA | 1 |
| Zimmerman, AL | 1 |
| Weiss, ER | 1 |
| Hao, Y | 1 |
| Dickerson, CD | 1 |
| Osawa, S | 1 |
| Shi, W | 1 |
| Zhang, L | 1 |
| Wong, F | 1 |
| Richards, SC | 1 |
| Creel, DJ | 1 |
| Saga, M | 1 |
| Mashima, Y | 1 |
| Akeo, K | 1 |
| Oguchi, Y | 1 |
| Kudoh, J | 1 |
| Shimizu, N | 1 |
| Trujillo, MJ | 1 |
| Garcia-Sandoval, B | 1 |
| Lorda-Sanchez, I | 1 |
| Gimenez, A | 1 |
| Sanz, R | 1 |
| Gonzalez-Gonzalez, MC | 1 |
| Ibañez, A | 1 |
| Ramos, C | 1 |
| Ayuso, C | 1 |
| Newbold, RJ | 1 |
| Deery, EC | 1 |
| Walker, CE | 1 |
| Wilkie, SE | 1 |
| Srinivasan, N | 1 |
| Hunt, DM | 1 |
| Warren, MJ | 1 |
| Hultberg, B | 1 |
| Ockerman, PA | 1 |
| Eriksson, O | 1 |
| Onisawa, J | 1 |
| Lee, TY | 1 |
| Taniguchi, N | 1 |
10 other studies available for serine and Retinitis Pigmentosa
| Article | Year |
|---|---|
Phenotype of retinitis pigmentosa associated with the Ser50Thr mutation in the NRL gene.
Topics: Adolescent; Adult; Basic-Leucine Zipper Transcription Factors; Child; Dark Adaptation; DNA-Binding P | 2003 |
Retinoids restore normal cyclic nucleotide sensitivity of mutant ion channels associated with cone dystrophy.
Topics: Animals; Asparagine; Cattle; Cyclic GMP; Cyclic Nucleotide-Gated Cation Channels; Humans; Ion Channe | 2006 |
Altered cAMP levels in retinas from transgenic mice expressing a rhodopsin mutant.
Topics: Animals; Apoptosis; Cyclic AMP; Guanosine 5'-O-(3-Thiotriphosphate); Mice; Mice, Transgenic; Mutatio | 1995 |
Pattern dystrophy and retinitis pigmentosa caused by a peripherin/RDS mutation.
Topics: Adult; Aged; Chromosome Aberrations; Chromosome Disorders; Chromosomes, Human, Pair 6; Eye Proteins; | 1995 |
A novel Cys-214-Ser mutation in the peripherin/RDS gene in a Japanese family with autosomal dominant retinitis pigmentosa.
Topics: Age of Onset; Base Sequence; Cysteine; DNA Mutational Analysis; DNA, Single-Stranded; Electrophoresi | 1993 |
Ser186Pro mutation of RHO gene in a Spanish autosomal dominant retinitis pigmentosa (ADRP) family.
Topics: Adult; DNA Mutational Analysis; Electroretinography; Female; Fundus Oculi; Genes, Dominant; Genotype | 2000 |
The destabilization of human GCAP1 by a proline to leucine mutation might cause cone-rod dystrophy.
Topics: Amino Acid Sequence; Animals; Calcium; Calcium-Binding Proteins; Cell Line; Circular Dichroism; Clon | 2001 |
Urinary amino acids in storage disorders: mucopolysaccharidosis, Gaucher's disease and metachromatic leucodystrophy.
Topics: Adolescent; Adult; Amino Acids; Carbohydrate Metabolism, Inborn Errors; Child; Child, Preschool; Dif | 1969 |
Biochemical studies of urinary acid mucopolysaccharide--peptide complexes in Hurler's syndrome.
Topics: Amino Acids; Aspartic Acid; Bone and Bones; Carbohydrate Metabolism, Inborn Errors; Child; Child, Pr | 1970 |
Age differences in the pattern of urinary glycosaminoglycan excretion in normal individuals.
Topics: Adolescent; Adult; Age Factors; Aged; Child; Child, Preschool; Chondroitin; Chromatography, Gas; Chr | 1972 |