serine has been researched along with Retinal Degeneration in 13 studies
Serine: A non-essential amino acid occurring in natural form as the L-isomer. It is synthesized from GLYCINE or THREONINE. It is involved in the biosynthesis of PURINES; PYRIMIDINES; and other amino acids.
serine : An alpha-amino acid that is alanine substituted at position 3 by a hydroxy group.
Retinal Degeneration: A retrogressive pathological change in the retina, focal or generalized, caused by genetic defects, inflammation, trauma, vascular disease, or aging. Degeneration affecting predominantly the macula lutea of the retina is MACULAR DEGENERATION. (Newell, Ophthalmology: Principles and Concepts, 7th ed, p304)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Transgenic mice expressing the rhodopsin mutant Pro347Ser (Serine 6) display retinal degeneration through apoptosis that is characteristic of the disease retinitis pigmentosa." | 3.69 | Altered cAMP levels in retinas from transgenic mice expressing a rhodopsin mutant. ( Dickerson, CD; Hao, Y; Osawa, S; Shi, W; Weiss, ER; Wong, F; Zhang, L, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (23.08) | 18.7374 |
| 1990's | 5 (38.46) | 18.2507 |
| 2000's | 3 (23.08) | 29.6817 |
| 2010's | 1 (7.69) | 24.3611 |
| 2020's | 1 (7.69) | 2.80 |
| Authors | Studies |
|---|---|
| Sinha, T | 1 |
| Ikelle, L | 1 |
| Naash, MI | 1 |
| Al-Ubaidi, MR | 1 |
| Mali, RS | 1 |
| Zhang, XM | 1 |
| Chintala, SK | 1 |
| Schatz, P | 1 |
| Abrahamson, M | 1 |
| Eksandh, L | 1 |
| Ponjavic, V | 1 |
| Andréasson, S | 1 |
| Lee, D | 1 |
| Geller, S | 1 |
| Walsh, N | 1 |
| Valter, K | 1 |
| Yasumura, D | 1 |
| Matthes, M | 1 |
| LaVail, M | 1 |
| Stone, J | 1 |
| Gao, YQ | 1 |
| Danciger, M | 1 |
| Ozgul, RK | 1 |
| Gribanova, Y | 1 |
| Jacobson, S | 1 |
| Farber, DB | 1 |
| Heckenlively, J | 1 |
| Weiss, ER | 1 |
| Hao, Y | 1 |
| Dickerson, CD | 1 |
| Osawa, S | 1 |
| Shi, W | 1 |
| Zhang, L | 1 |
| Wong, F | 1 |
| Richards, SC | 1 |
| Creel, DJ | 1 |
| Nakazawa, M | 1 |
| Kikawa, E | 1 |
| Chida, Y | 1 |
| Wada, Y | 1 |
| Shiono, T | 1 |
| Tamai, M | 1 |
| Li, T | 1 |
| Snyder, WK | 1 |
| Olsson, JE | 1 |
| Dryja, TP | 1 |
| Fishman, GA | 1 |
| Stone, EM | 1 |
| Alexander, KR | 1 |
| Gilbert, LD | 1 |
| Derlacki, DJ | 1 |
| Butler, NS | 1 |
| Schmidt, SY | 1 |
| Berson, EL | 1 |
| Hayes, KC | 1 |
| Ionasescu, V | 1 |
| Stegink, L | 1 |
| Mueller, S | 1 |
| Weinstein, M | 1 |
1 review available for serine and Retinal Degeneration
| Article | Year |
|---|---|
The Intersection of Serine Metabolism and Cellular Dysfunction in Retinal Degeneration.
Topics: Humans; Retinal Degeneration; Serine | 2020 |
12 other studies available for serine and Retinal Degeneration
| Article | Year |
|---|---|
A decrease in phosphorylation of cAMP-response element-binding protein (CREBP) promotes retinal degeneration.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Amacrine Cells; Animals; Apoptosis; Blotting, Western; CREB-Bi | 2011 |
Macular appearance by means of OCT and electrophysiology in members of two families with different mutations in RDS (the peripherin/RDS gene).
Topics: Adult; Aged; Aged, 80 and over; Amino Acid Substitution; Arginine; Codon, Terminator; Electroretinog | 2003 |
Photoreceptor degeneration in Pro23His and S334ter transgenic rats.
Topics: Animals; Animals, Genetically Modified; Animals, Newborn; Apoptosis; Histidine; In Situ Nick-End Lab | 2003 |
Association of the Asn306Ser variant of the SP4 transcription factor and an intronic variant in the beta-subunit of transducin with digenic disease.
Topics: Adenine; Asparagine; Blindness; Cohort Studies; Exons; Genetic Variation; GTP-Binding Protein beta S | 2007 |
Possible syndrome of high myopia with retinal degeneration, cataract, manic depression, and elevated plasma amino acids.
Topics: Aged; Amino Acids; Bipolar Disorder; Cataract; Female; Humans; Lysine; Male; Middle Aged; Myopia; Or | 1980 |
Altered cAMP levels in retinas from transgenic mice expressing a rhodopsin mutant.
Topics: Animals; Apoptosis; Cyclic AMP; Guanosine 5'-O-(3-Thiotriphosphate); Mice; Mice, Transgenic; Mutatio | 1995 |
Pattern dystrophy and retinitis pigmentosa caused by a peripherin/RDS mutation.
Topics: Adult; Aged; Chromosome Aberrations; Chromosome Disorders; Chromosomes, Human, Pair 6; Eye Proteins; | 1995 |
Autosomal dominant cone-rod dystrophy associated with mutations in codon 244 (Asn244His) and codon 184 (Tyr184Ser) of the peripherin/RDS gene.
Topics: Adult; Aged; Amino Acid Sequence; Asparagine; Base Sequence; Codon; DNA; Electroretinography; Eye Pr | 1996 |
Transgenic mice carrying the dominant rhodopsin mutation P347S: evidence for defective vectorial transport of rhodopsin to the outer segments.
Topics: Animals; Electroretinography; Genes, Dominant; Humans; Mice; Mice, Transgenic; Microscopy, Confocal; | 1996 |
Serine-27-phenylalanine mutation within the peripherin/RDS gene in a family with cone dystrophy.
Topics: Adult; Aged; DNA; Electrophoresis, Agar Gel; Electroretinography; Eye Proteins; Fundus Oculi; Humans | 1997 |
Retinal degeneration in cats fed casein. I. Taurine deficiency.
Topics: Animals; Caseins; Cats; Cysteine; Dietary Proteins; DNA; Eating; Electroretinography; Glutamine; Gly | 1976 |
Amino acid abnormality in Sjögren-Larsson syndrome.
Topics: Adolescent; Amino Acid Metabolism, Inborn Errors; Dental Enamel Hypoplasia; Epilepsy; Ethylamines; G | 1973 |