serine has been researched along with Reperfusion Injury in 28 studies
Serine: A non-essential amino acid occurring in natural form as the L-isomer. It is synthesized from GLYCINE or THREONINE. It is involved in the biosynthesis of PURINES; PYRIMIDINES; and other amino acids.
serine : An alpha-amino acid that is alanine substituted at position 3 by a hydroxy group.
Reperfusion Injury: Adverse functional, metabolic, or structural changes in tissues that result from the restoration of blood flow to the tissue (REPERFUSION) following ISCHEMIA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To observe the therapeutic time window of L-serine against focal cerebral ischemia/reperfusion injury in rats, and related mechanisms." | 7.76 | [Experimental study of therapeutic time window of L-serine against focal cerebral ischemia/reperfusion injury in rats]. ( Fan, XJ; Jiang, ZL; Shen, LH; Wang, GH; Zhang, XG, 2010) |
| " Using quantitative phosphoproteomics technology, we identified that SGK3 (serine/threonine-protein kinase 3) in the neonatal heart is highly expressed and activated after myocardial infarction." | 4.02 | Serine/Threonine-Protein Kinase 3 Facilitates Myocardial Repair After Cardiac Injury Possibly Through the Glycogen Synthase Kinase-3β/β-Catenin Pathway. ( Chen, BR; Chen, F; Du, C; Fan, Y; Gu, LF; Guo, XJ; Kong, XQ; Li, YF; Liu, L; Ma, Y; Shan, TK; Sun, JT; Sun, R; Wang, H; Wang, LS; Wang, ZM; Wei, TW; Wei, YY; Yang, TT, 2021) |
| "Chronic nicotine (Ch-NIC) exposure exacerbates ischemia/reperfusion (I/R)-induced oxidative stress and acute kidney injury (AKI), and mitochondrial production of reactive oxygen species (ROS) in cultured renal proximal tubule cells (RPTCs)." | 3.79 | Chronic nicotine exposure augments renal oxidative stress and injury through transcriptional activation of p66shc. ( Arany, I; Clark, J; Juncos, LA; Reed, DK, 2013) |
| "To observe the therapeutic time window of L-serine against focal cerebral ischemia/reperfusion injury in rats, and related mechanisms." | 3.76 | [Experimental study of therapeutic time window of L-serine against focal cerebral ischemia/reperfusion injury in rats]. ( Fan, XJ; Jiang, ZL; Shen, LH; Wang, GH; Zhang, XG, 2010) |
| "However, hypoxia within tumors is often transient and is inevitably followed by reoxygenation." | 1.32 | ATR/ATM targets are phosphorylated by ATR in response to hypoxia and ATM in response to reoxygenation. ( Dorie, MJ; Giaccia, AJ; Hammond, EM, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 10 (35.71) | 29.6817 |
| 2010's | 14 (50.00) | 24.3611 |
| 2020's | 4 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Li, YF | 1 |
| Wei, TW | 1 |
| Fan, Y | 1 |
| Shan, TK | 1 |
| Sun, JT | 1 |
| Chen, BR | 1 |
| Wang, ZM | 1 |
| Gu, LF | 1 |
| Yang, TT | 1 |
| Liu, L | 1 |
| Du, C | 1 |
| Ma, Y | 1 |
| Wang, H | 1 |
| Sun, R | 1 |
| Wei, YY | 1 |
| Chen, F | 1 |
| Guo, XJ | 1 |
| Kong, XQ | 1 |
| Wang, LS | 1 |
| Kalpage, HA | 1 |
| Vaishnav, A | 1 |
| Liu, J | 1 |
| Varughese, A | 1 |
| Wan, J | 1 |
| Turner, AA | 1 |
| Ji, Q | 1 |
| Zurek, MP | 1 |
| Kapralov, AA | 1 |
| Kagan, VE | 1 |
| Brunzelle, JS | 1 |
| Recanati, MA | 1 |
| Grossman, LI | 1 |
| Sanderson, TH | 1 |
| Lee, I | 1 |
| Salomon, AR | 1 |
| Edwards, BFP | 1 |
| Hüttemann, M | 1 |
| Qasim, W | 1 |
| Li, Y | 1 |
| Sun, RM | 1 |
| Feng, DC | 1 |
| Wang, ZY | 1 |
| Liu, DS | 1 |
| Yao, JH | 1 |
| Tian, XF | 1 |
| Ni, M | 2 |
| Zhou, H | 1 |
| Zhang, J | 1 |
| Jin, D | 1 |
| Lu, T | 2 |
| Busuttil, RW | 1 |
| Kupiec-Weglinski, JW | 1 |
| Wang, X | 3 |
| Zhai, Y | 1 |
| Hurst, S | 1 |
| Gonnot, F | 1 |
| Dia, M | 1 |
| Crola Da Silva, C | 1 |
| Gomez, L | 1 |
| Sheu, SS | 1 |
| Tang, B | 1 |
| Ma, J | 1 |
| Ha, X | 1 |
| Zhang, Y | 1 |
| Xing, Y | 1 |
| Nakade, Y | 1 |
| Iwata, Y | 1 |
| Furuichi, K | 1 |
| Mita, M | 2 |
| Hamase, K | 2 |
| Konno, R | 2 |
| Miyake, T | 1 |
| Sakai, N | 1 |
| Kitajima, S | 1 |
| Toyama, T | 1 |
| Shinozaki, Y | 1 |
| Sagara, A | 1 |
| Miyagawa, T | 1 |
| Hara, A | 1 |
| Shimizu, M | 1 |
| Kamikawa, Y | 1 |
| Sato, K | 1 |
| Oshima, M | 1 |
| Yoneda-Nakagawa, S | 1 |
| Yamamura, Y | 1 |
| Kaneko, S | 1 |
| Miyamoto, T | 1 |
| Katane, M | 1 |
| Homma, H | 1 |
| Morita, H | 1 |
| Suda, W | 1 |
| Hattori, M | 1 |
| Wada, T | 1 |
| Zou, Y | 1 |
| Zhou, X | 1 |
| Peng, W | 1 |
| Hu, Z | 1 |
| Chen, L | 1 |
| Luo, Z | 1 |
| Fu, W | 1 |
| Liao, X | 1 |
| Cui, Z | 1 |
| Zhou, J | 1 |
| Liu, CL | 1 |
| He, YY | 1 |
| Li, X | 1 |
| Li, RJ | 1 |
| He, KL | 1 |
| Wang, LL | 1 |
| Sasabe, J | 1 |
| Suzuki, M | 1 |
| Miyoshi, Y | 1 |
| Tojo, Y | 1 |
| Okamura, C | 1 |
| Ito, S | 1 |
| Aiso, S | 1 |
| Wei, XE | 1 |
| Zhang, FY | 1 |
| Wang, K | 1 |
| Zhang, QX | 1 |
| Rong, LQ | 1 |
| Song, H | 1 |
| Pu, J | 1 |
| Wang, L | 1 |
| Wu, L | 1 |
| Xiao, J | 1 |
| Liu, Q | 1 |
| Chen, J | 2 |
| Zhang, M | 1 |
| Liu, Y | 1 |
| Mo, J | 1 |
| Zheng, Y | 1 |
| Wan, D | 1 |
| Cai, X | 1 |
| Cao, Y | 1 |
| Xiao, W | 1 |
| Ye, L | 1 |
| Tu, E | 1 |
| Lin, Z | 1 |
| Wen, J | 1 |
| Lu, X | 1 |
| He, J | 1 |
| Peng, Y | 1 |
| Su, J | 1 |
| Zhang, H | 1 |
| Zhao, Y | 1 |
| Lin, M | 1 |
| Zhang, Z | 1 |
| Li, L | 1 |
| Zhi, D | 1 |
| Shen, Y | 1 |
| Liu, K | 1 |
| Li, H | 1 |
| Russo, R | 1 |
| Cavaliere, F | 1 |
| Berliocchi, L | 1 |
| Nucci, C | 1 |
| Gliozzi, M | 1 |
| Mazzei, C | 1 |
| Tassorelli, C | 1 |
| Corasaniti, MT | 1 |
| Rotiroti, D | 1 |
| Bagetta, G | 1 |
| Morrone, LA | 1 |
| Qian, J | 1 |
| Ren, X | 1 |
| Zhang, P | 1 |
| Jones, WK | 1 |
| Molkentin, JD | 2 |
| Fan, GC | 1 |
| Kranias, EG | 1 |
| Wang, GH | 1 |
| Jiang, ZL | 1 |
| Zhang, XG | 1 |
| Shen, LH | 1 |
| Fan, XJ | 1 |
| Xia, Y | 1 |
| Rao, J | 1 |
| Yao, A | 1 |
| Zhang, F | 1 |
| Li, G | 1 |
| Lu, L | 1 |
| Joiner, ML | 1 |
| Koval, OM | 1 |
| Li, J | 1 |
| He, BJ | 1 |
| Allamargot, C | 1 |
| Gao, Z | 1 |
| Luczak, ED | 1 |
| Hall, DD | 1 |
| Fink, BD | 1 |
| Chen, B | 1 |
| Yang, J | 1 |
| Moore, SA | 1 |
| Scholz, TD | 1 |
| Strack, S | 1 |
| Mohler, PJ | 1 |
| Sivitz, WI | 1 |
| Song, LS | 1 |
| Anderson, ME | 1 |
| Arany, I | 1 |
| Clark, J | 1 |
| Reed, DK | 1 |
| Juncos, LA | 1 |
| Hammond, EM | 1 |
| Dorie, MJ | 1 |
| Giaccia, AJ | 1 |
| Wang, J | 1 |
| Liu, S | 1 |
| Fu, Y | 1 |
| Wang, JH | 1 |
| Lu, Y | 1 |
| Kaiser, RA | 1 |
| Liang, Q | 1 |
| Bueno, O | 1 |
| Huang, Y | 1 |
| Lackey, T | 1 |
| Klevitsky, R | 1 |
| Hewett, TE | 1 |
| Ohi, N | 1 |
| Nishikawa, Y | 1 |
| Tokairin, T | 1 |
| Yamamoto, Y | 1 |
| Doi, Y | 1 |
| Omori, Y | 1 |
| Enomoto, K | 1 |
| Morioka, M | 1 |
| Kawano, T | 1 |
| Yano, S | 1 |
| Kai, Y | 1 |
| Tsuiki, H | 1 |
| Yoshinaga, Y | 1 |
| Matsumoto, J | 1 |
| Maeda, T | 1 |
| Hamada, J | 1 |
| Yamamoto, H | 1 |
| Fukunaga, K | 1 |
| Kuratsu, J | 1 |
| Stephanou, A | 1 |
| Scarabelli, TM | 1 |
| Brar, BK | 1 |
| Nakanishi, Y | 1 |
| Matsumura, M | 1 |
| Knight, RA | 1 |
| Latchman, DS | 1 |
| Friguls, B | 1 |
| Justicia, C | 1 |
| Pallàs, M | 1 |
| Planas, AM | 1 |
| Vittone, L | 1 |
| Mundiña-Weilenmann, C | 1 |
| Said, M | 1 |
| Ferrero, P | 1 |
| Mattiazzi, A | 1 |
28 other studies available for serine and Reperfusion Injury
| Article | Year |
|---|---|
Serine/Threonine-Protein Kinase 3 Facilitates Myocardial Repair After Cardiac Injury Possibly Through the Glycogen Synthase Kinase-3β/β-Catenin Pathway.
Topics: Animals; Apoptosis; beta Catenin; Glycogen Synthase Kinase 3 beta; Mice; Myocardial Infarction; Myoc | 2021 |
Serine-47 phosphorylation of cytochrome
Topics: Animals; Apoptosis; Brain; Caspase 3; Cell Respiration; Crystallography, X-Ray; Cytochromes c; Elect | 2019 |
PTEN-induced kinase 1-induced dynamin-related protein 1 Ser637 phosphorylation reduces mitochondrial fission and protects against intestinal ischemia reperfusion injury.
Topics: Animals; Apoptosis; Caco-2 Cells; Cell Hypoxia; Disease Models, Animal; Dynamins; Gene Knockdown Tec | 2020 |
Isoform- and Cell Type-Specific Roles of Glycogen Synthase Kinase 3 N-Terminal Serine Phosphorylation in Liver Ischemia Reperfusion Injury.
Topics: Animals; Autophagy; Cell Death; Glycogen Synthase Kinase 3; Hepatocytes; Immunity, Innate; Inflammat | 2020 |
Phosphorylation of cyclophilin D at serine 191 regulates mitochondrial permeability transition pore opening and cell death after ischemia-reperfusion.
Topics: Animals; Cell Death; Ischemia; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mitochondria; Mitocho | 2020 |
Tumor necrosis factor-alpha upregulated PHLPP1 through activating nuclear factor-kappa B during myocardial ischemia/reperfusion.
Topics: Animals; Animals, Newborn; Disease Models, Animal; Gene Expression Regulation; Heart Ventricles; Mal | 2018 |
Gut microbiota-derived D-serine protects against acute kidney injury.
Topics: Acute Kidney Injury; Administration, Oral; Animals; Biomarkers; Disease Models, Animal; Dysbiosis; F | 2018 |
The mechanism on phosphorylation of Hsp20Ser16 inhibit GA stress and ER stress during OGD/R.
Topics: Animals; Cell Line, Tumor; Endoplasmic Reticulum; Endoplasmic Reticulum Stress; Glucose; Golgi Appar | 2019 |
Detection of urinary metabolomics before and after Pringle maneuver-induced liver ischemia and reperfusion injury in rats using gas chromatography-mass spectrometry.
Topics: Alanine; Alanine Transaminase; Animals; Bilirubin; Gas Chromatography-Mass Spectrometry; Glycerophos | 2013 |
Inhibition of serine/threonine protein phosphatase PP1 protects cardiomyocytes from tunicamycin-induced apoptosis and I/R through the upregulation of p-eIF2α.
Topics: Animals; Apoptosis; Cell Survival; Eukaryotic Initiation Factor-2; Myocytes, Cardiac; Phosphoprotein | 2014 |
Ischemic acute kidney injury perturbs homeostasis of serine enantiomers in the body fluid in mice: early detection of renal dysfunction using the ratio of serine enantiomers.
Topics: Acute Kidney Injury; Acute-Phase Proteins; Animals; Creatinine; Cystatin C; D-Amino-Acid Oxidase; Hu | 2014 |
Fasudil hydrochloride protects neurons in rat hippocampal CA1 region through inhibiting GluR6-MLK3-JNKs signal pathway.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; CA1 Region, Hippocampal; Caspase 3; Cytoprot | 2014 |
ATG16L1 phosphorylation is oppositely regulated by CSNK2/casein kinase 2 and PPP1/protein phosphatase 1 which determines the fate of cardiomyocytes during hypoxia/reoxygenation.
Topics: Amino Acid Sequence; Animals; Apoptosis; Autophagy; Autophagy-Related Protein 5; Autophagy-Related P | 2015 |
Effects of CC-chemokine receptor 5 on ROCK2 and P-MLC2 expression after focal cerebral ischaemia-reperfusion injury in rats.
Topics: Analysis of Variance; Animals; Brain Infarction; Cardiac Myosins; Disease Models, Animal; In Situ Ni | 2016 |
Modulation of pro-survival and death-associated pathways under retinal ischemia/reperfusion: effects of NMDA receptor blockade.
Topics: Analysis of Variance; Androstadienes; Animals; bcl-Associated Death Protein; Cell Death; Chromones; | 2008 |
Blockade of Hsp20 phosphorylation exacerbates cardiac ischemia/reperfusion injury by suppressed autophagy and increased cell death.
Topics: Alanine; Animals; Apoptosis; Autophagy; Base Sequence; Disease Models, Animal; Heart Failure; HSP20 | 2009 |
[Experimental study of therapeutic time window of L-serine against focal cerebral ischemia/reperfusion injury in rats].
Topics: Animals; Brain Ischemia; Interleukin-6; Male; Neuroprotective Agents; Oxidative Stress; Rats; Rats, | 2010 |
Lithium exacerbates hepatic ischemia/reperfusion injury by inhibiting GSK-3β/NF-κB-mediated protective signaling in mice.
Topics: Animals; Apoptosis; CASP8 and FADD-Like Apoptosis Regulating Protein; Caspase 3; Disease Models, Ani | 2012 |
CaMKII determines mitochondrial stress responses in heart.
Topics: Animals; Apoptosis; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cyclosporine; Femal | 2012 |
Chronic nicotine exposure augments renal oxidative stress and injury through transcriptional activation of p66shc.
Topics: Acute Kidney Injury; Animals; Blotting, Western; Cells, Cultured; Cytochromes c; Hydrogen Peroxide; | 2013 |
ATR/ATM targets are phosphorylated by ATR in response to hypoxia and ATM in response to reoxygenation.
Topics: Ataxia Telangiectasia Mutated Proteins; Cell Cycle Proteins; Cell Line; DNA Damage; DNA-Activated Pr | 2003 |
Cdk5 activation induces hippocampal CA1 cell death by directly phosphorylating NMDA receptors.
Topics: Amino Acid Sequence; Animals; Brain Ischemia; Cell Death; Cyclin-Dependent Kinase 5; Cyclin-Dependen | 2003 |
Genetic inhibition or activation of JNK1/2 protects the myocardium from ischemia-reperfusion-induced cell death in vivo.
Topics: Animals; Apoptosis; Blotting, Western; Cell Death; Cell Size; Echocardiography; Heart; In Situ Nick- | 2005 |
Maintenance of Bad phosphorylation prevents apoptosis of rat hepatic sinusoidal endothelial cells in vitro and in vivo.
Topics: 14-3-3 Proteins; Animals; Apoptosis; bcl-Associated Death Protein; Caspase 3; Caspase 9; Caspases; C | 2006 |
Hyperphosphorylation at serine 199/202 of tau factor in the gerbil hippocampus after transient forebrain ischemia.
Topics: Animals; Apoptosis; Binding Sites; Brain Ischemia; Gerbillinae; Hippocampus; Male; Phosphorylation; | 2006 |
Induction of apoptosis and Fas receptor/Fas ligand expression by ischemia/reperfusion in cardiac myocytes requires serine 727 of the STAT-1 transcription factor but not tyrosine 701.
Topics: Animals; Animals, Newborn; Apoptosis; Blotting, Western; Cells, Cultured; DNA; DNA-Binding Proteins; | 2001 |
Focal cerebral ischemia causes two temporal waves of Akt activation.
Topics: Amino Acid Sequence; Animals; Apoptosis; bcl-Associated Death Protein; Brain Ischemia; Carrier Prote | 2001 |
Time course and mechanisms of phosphorylation of phospholamban residues in ischemia-reperfused rat hearts. Dissociation of phospholamban phosphorylation pathways.
Topics: Animals; Blotting, Western; Calcium; Calcium-Binding Proteins; Catecholamines; Cyclic AMP-Dependent | 2002 |