serine has been researched along with Renal Insufficiency in 4 studies
Serine: A non-essential amino acid occurring in natural form as the L-isomer. It is synthesized from GLYCINE or THREONINE. It is involved in the biosynthesis of PURINES; PYRIMIDINES; and other amino acids.
serine : An alpha-amino acid that is alanine substituted at position 3 by a hydroxy group.
Renal Insufficiency: Conditions in which the KIDNEYS perform below the normal level in the ability to remove wastes, concentrate URINE, and maintain ELECTROLYTE BALANCE; BLOOD PRESSURE; and CALCIUM metabolism. Renal insufficiency can be classified by the degree of kidney damage (as measured by the level of PROTEINURIA) and reduction in GLOMERULAR FILTRATION RATE.
| Excerpt | Relevance | Reference |
|---|---|---|
| " No subjects experienced serious adverse events or discontinued treatment due to adverse events." | 1.72 | Safety and Pharmacokinetics of Taniborbactam (VNRX-5133) with Cefepime in Subjects with Various Degrees of Renal Impairment. ( Dowell, JA; Henkel, T; Marbury, TC; Smith, WB, 2022) |
| "Salt-induced hypertension is one of the major issues worldwide and one of the main factors involved in heart and kidney failure." | 1.72 | Benincasa hispida extracts positively regulated high salt-induced hypertension in Dahl salt-sensitive rats: Impact on biochemical profile and metabolic patterns. ( Ahmad, H; Ahmad, N; Chen, M; Du, J; Jin, Y; Khan, A; Li, X; Ouyang, Y; Tian, Z; Yang, P; Yang, Z; Zeng, L; Zhao, X; Zheng, X, 2022) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 3 (75.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dowell, JA | 1 |
| Marbury, TC | 1 |
| Smith, WB | 1 |
| Henkel, T | 1 |
| Ahmad, H | 1 |
| Zhao, X | 1 |
| Ahmad, N | 1 |
| Khan, A | 1 |
| Jin, Y | 1 |
| Du, J | 1 |
| Zheng, X | 1 |
| Zeng, L | 1 |
| Ouyang, Y | 1 |
| Yang, P | 1 |
| Chen, M | 1 |
| Li, X | 1 |
| Yang, Z | 1 |
| Tian, Z | 1 |
| Tseng, YS | 1 |
| Liao, CH | 1 |
| Wu, WB | 1 |
| Ma, MC | 1 |
| Rysz, J | 1 |
| Guga, P | 1 |
| Ciałkowska-Rysz, A | 1 |
| Grycewicz, T | 1 |
| Markuszewski, L | 1 |
| Kujawski, K | 1 |
| Błaszczak, R | 1 |
| Olszewski, R | 1 |
| Luciak, M | 1 |
| Banach, M | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Phase 1, Open-Label, Single-Dose Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of VNRX-5133 With VNRX-5022 in Subjects With Varying Degrees of Renal Impairment[NCT03690362] | Phase 1 | 33 participants (Actual) | Interventional | 2018-04-06 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 other studies available for serine and Renal Insufficiency
| Article | Year |
|---|---|
Safety and Pharmacokinetics of Taniborbactam (VNRX-5133) with Cefepime in Subjects with Various Degrees of Renal Impairment.
Topics: Anti-Bacterial Agents; beta-Lactamase Inhibitors; beta-Lactamases; Borinic Acids; Carboxylic Acids; | 2022 |
Benincasa hispida extracts positively regulated high salt-induced hypertension in Dahl salt-sensitive rats: Impact on biochemical profile and metabolic patterns.
Topics: Alanine; Amino Acids; Animals; Antihypertensive Agents; Antioxidants; Aspartic Acid; Cucurbitaceae; | 2022 |
Topics: Animals; Calcium; Disease Models, Animal; Excitatory Amino Acid Antagonists; Kidney Tubules, Proxima | 2021 |
[Blood serum and neutrophil amino acid concentrations during hemodialysis].
Topics: Adult; Arginine; Cysteine; Female; Humans; Male; Neutrophils; Renal Dialysis; Renal Insufficiency; S | 2005 |