Page last updated: 2024-11-08

serine and Pulmonary Hypertension

serine has been researched along with Pulmonary Hypertension in 4 studies

Serine: A non-essential amino acid occurring in natural form as the L-isomer. It is synthesized from GLYCINE or THREONINE. It is involved in the biosynthesis of PURINES; PYRIMIDINES; and other amino acids.
serine : An alpha-amino acid that is alanine substituted at position 3 by a hydroxy group.

Research Excerpts

ExcerptRelevanceReference
" Parallel experiments were performed in rat lung sections and PASMCs and in rodent PAH models induced by the HIF-1α activator, cobalt, chronic hypoxia, and monocrotaline."3.78Dynamin-related protein 1-mediated mitochondrial mitotic fission permits hyperproliferation of vascular smooth muscle cells and offers a novel therapeutic target in pulmonary hypertension. ( Archer, SL; Chen, Y; Fang, YH; Hong, Z; Marsboom, G; Morrow, E; Piao, L; Pogoriler, J; Rehman, J; Ryan, JJ; Thenappan, T; Toth, PT; Weir, EK; Wu, X; Zhang, HJ, 2012)
"In the pulmonary artery isolated from 1-week hypoxia-induced pulmonary hypertensive rats, endothelial NO production stimulated by carbachol was decreased significantly in in situ visualization using diaminofluorescein-2 diacetate and also in cGMP content."3.71Decreased endothelial nitric-oxide synthase (eNOS) activity resulting from abnormal interaction between eNOS and its regulatory proteins in hypoxia-induced pulmonary hypertension. ( Hori, M; Karaki, H; Murata, T; Ozaki, H; Sato, K, 2002)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (25.00)29.6817
2010's3 (75.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Guo, D1
Gu, J1
Jiang, H1
Ahmed, A1
Zhang, Z1
Gu, Y1
Marsboom, G1
Toth, PT1
Ryan, JJ1
Hong, Z1
Wu, X1
Fang, YH1
Thenappan, T1
Piao, L1
Zhang, HJ1
Pogoriler, J1
Chen, Y1
Morrow, E1
Weir, EK1
Rehman, J1
Archer, SL1
Wojciak-Stothard, B1
Zhao, L1
Oliver, E1
Dubois, O1
Wu, Y1
Kardassis, D1
Vasilaki, E1
Huang, M1
Mitchell, JA1
Harrington, LS1
Louise, H1
Prendergast, GC1
Wilkins, MR1
Murata, T1
Sato, K1
Hori, M1
Ozaki, H1
Karaki, H1

Other Studies

4 other studies available for serine and Pulmonary Hypertension

ArticleYear
Inhibition of pyruvate kinase M2 by reactive oxygen species contributes to the development of pulmonary arterial hypertension.
    Journal of molecular and cellular cardiology, 2016, Volume: 91

    Topics: Acetophenones; Acetylcysteine; Animals; Apoptosis; Calcium; Calcium Channels, L-Type; Cell Prolifera

2016
Dynamin-related protein 1-mediated mitochondrial mitotic fission permits hyperproliferation of vascular smooth muscle cells and offers a novel therapeutic target in pulmonary hypertension.
    Circulation research, 2012, May-25, Volume: 110, Issue:11

    Topics: Animals; Antihypertensive Agents; Case-Control Studies; CDC2 Protein Kinase; Cell Cycle Checkpoints;

2012
Role of RhoB in the regulation of pulmonary endothelial and smooth muscle cell responses to hypoxia.
    Circulation research, 2012, May-25, Volume: 110, Issue:11

    Topics: Actomyosin; Animals; Capillary Permeability; Cell Hypoxia; Cell Movement; Cell Proliferation; Cells,

2012
Decreased endothelial nitric-oxide synthase (eNOS) activity resulting from abnormal interaction between eNOS and its regulatory proteins in hypoxia-induced pulmonary hypertension.
    The Journal of biological chemistry, 2002, Nov-15, Volume: 277, Issue:46

    Topics: Animals; Blotting, Western; Body Weight; Calcium; Carbachol; Cell Membrane; Cyclic GMP; Electrophore

2002