Page last updated: 2024-11-08

serine and Proteinuria

serine has been researched along with Proteinuria in 7 studies

Serine: A non-essential amino acid occurring in natural form as the L-isomer. It is synthesized from GLYCINE or THREONINE. It is involved in the biosynthesis of PURINES; PYRIMIDINES; and other amino acids.
serine : An alpha-amino acid that is alanine substituted at position 3 by a hydroxy group.

Proteinuria: The presence of proteins in the urine, an indicator of KIDNEY DISEASES.

Research Excerpts

ExcerptRelevanceReference
"Administration of D-serine to rats induced acute necrosis of the proximal straight tubules, proteinuria, glucosuria, and aminoaciduria."7.65D-serine nephrotoxicity. The nature of proteinuria, glucosuria, and aminoaciduria in acute tubular necrosis. ( Carone, FA; Ganote, CE, 1975)
"Administration of D-serine to rats induced acute necrosis of the proximal straight tubules, proteinuria, glucosuria, and aminoaciduria."3.65D-serine nephrotoxicity. The nature of proteinuria, glucosuria, and aminoaciduria in acute tubular necrosis. ( Carone, FA; Ganote, CE, 1975)
" Alderely Park (Wistar-derived) rats were dosed with either D-serine (250 mg/kg ip) or vehicle (deionised water) and urine was collected at 0-12, 12-24, 24-36 and 36-48 h post-dosing."1.33D-Serine-induced nephrotoxicity: a HPLC-TOF/MS-based metabonomics approach. ( Lenz, EM; Lock, EA; Major, H; Williams, RE; Wilson, ID, 2005)
"In maleic acid-treated rats the site and extent of tubular necrosis and the nature of urinary loss of solutes were studied."1.27Urinary loss of glucose, phosphate, and protein by diffusion into proximal straight tubules injured by D-serine and maleic acid. ( Carone, FA; Goldman, B; Nakamura, S, 1985)
"In similarly treated rats, proteinuria and glucosuria developed at the onset of tubular necrosis and disappeared when the tubules were completely relined by epithelium suggesting that they are due to diffusion of protein and glucose from interstitium into tubular fluid across the denuded basement membranes and that epithelial cells, under normal conditions, act as a barrier to diffusion of certain substances between the interstitium and tubular fluid."1.25The nature of D-serine--induced nephrotoxicity. ( Carone, FA; Ganote, CE; Peterson, DR, 1974)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19905 (71.43)18.7374
1990's0 (0.00)18.2507
2000's1 (14.29)29.6817
2010's1 (14.29)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Tudpor, K1
LaĆ­nez, S1
Kwakernaak, AJ1
Kovalevskaya, NV1
Verkaart, S1
van Genesen, S1
van der Kemp, A1
Navis, G1
Bindels, RJ1
Hoenderop, JG1
Williams, RE1
Major, H1
Lock, EA1
Lenz, EM1
Wilson, ID1
Carone, FA3
Ganote, CE2
Nakamura, S1
Goldman, B1
Peterson, DR1
Rubin, HM1
Giorgio, AJ1
Macdonald, RR1
Linarelli, LG1
Cuppage, FE1
Tate, A1

Other Studies

7 other studies available for serine and Proteinuria

ArticleYear
Urinary plasmin inhibits TRPV5 in nephrotic-range proteinuria.
    Journal of the American Society of Nephrology : JASN, 2012, Volume: 23, Issue:11

    Topics: Amino Acid Sequence; Base Sequence; Calcium; Calcium Signaling; Calmodulin; Fibrinolysin; HEK293 Cel

2012
D-Serine-induced nephrotoxicity: a HPLC-TOF/MS-based metabonomics approach.
    Toxicology, 2005, Feb-14, Volume: 207, Issue:2

    Topics: Animals; Chromatography, High Pressure Liquid; Glycosuria; Kidney; Kidney Tubular Necrosis, Acute; M

2005
D-serine nephrotoxicity. The nature of proteinuria, glucosuria, and aminoaciduria in acute tubular necrosis.
    Archives of pathology, 1975, Volume: 99, Issue:12

    Topics: Acute Kidney Injury; Animals; Glycosuria; Kidney Tubular Necrosis, Acute; Kidney Tubules; Male; Pota

1975
Urinary loss of glucose, phosphate, and protein by diffusion into proximal straight tubules injured by D-serine and maleic acid.
    Laboratory investigation; a journal of technical methods and pathology, 1985, Volume: 52, Issue:6

    Topics: Acute Kidney Injury; Animals; Carbon Radioisotopes; Glomerular Filtration Rate; Glucose; Glycosuria;

1985
The nature of D-serine--induced nephrotoxicity.
    The American journal of pathology, 1974, Volume: 77, Issue:2

    Topics: Acute Kidney Injury; Animals; Cytoplasm; Diffusion; Epithelial Cells; Epithelium; Glycosuria; Kidney

1974
Selective malabsorption of vitamin B 12: report of a case with metabolic studies.
    American journal of diseases of children (1960), 1974, Volume: 127, Issue:5

    Topics: Alanine; Amino Acids; Anemia, Macrocytic; Child; Chromatography, Gas; Glycine; Hemoglobins; Histidin

1974
Repair of the nephron in acute renal failure: comparative regeneration following various forms of acute tubular injury.
    Pathologia et microbiologia, 1968, Volume: 32, Issue:6

    Topics: Acute Kidney Injury; Animals; Chromates; Creatinine; Ischemia; Kidney Function Tests; Kidney Tubules

1968