serine has been researched along with Proteinuria in 7 studies
Serine: A non-essential amino acid occurring in natural form as the L-isomer. It is synthesized from GLYCINE or THREONINE. It is involved in the biosynthesis of PURINES; PYRIMIDINES; and other amino acids.
serine : An alpha-amino acid that is alanine substituted at position 3 by a hydroxy group.
Proteinuria: The presence of proteins in the urine, an indicator of KIDNEY DISEASES.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Administration of D-serine to rats induced acute necrosis of the proximal straight tubules, proteinuria, glucosuria, and aminoaciduria." | 7.65 | D-serine nephrotoxicity. The nature of proteinuria, glucosuria, and aminoaciduria in acute tubular necrosis. ( Carone, FA; Ganote, CE, 1975) |
| "Administration of D-serine to rats induced acute necrosis of the proximal straight tubules, proteinuria, glucosuria, and aminoaciduria." | 3.65 | D-serine nephrotoxicity. The nature of proteinuria, glucosuria, and aminoaciduria in acute tubular necrosis. ( Carone, FA; Ganote, CE, 1975) |
| " Alderely Park (Wistar-derived) rats were dosed with either D-serine (250 mg/kg ip) or vehicle (deionised water) and urine was collected at 0-12, 12-24, 24-36 and 36-48 h post-dosing." | 1.33 | D-Serine-induced nephrotoxicity: a HPLC-TOF/MS-based metabonomics approach. ( Lenz, EM; Lock, EA; Major, H; Williams, RE; Wilson, ID, 2005) |
| "In maleic acid-treated rats the site and extent of tubular necrosis and the nature of urinary loss of solutes were studied." | 1.27 | Urinary loss of glucose, phosphate, and protein by diffusion into proximal straight tubules injured by D-serine and maleic acid. ( Carone, FA; Goldman, B; Nakamura, S, 1985) |
| "In similarly treated rats, proteinuria and glucosuria developed at the onset of tubular necrosis and disappeared when the tubules were completely relined by epithelium suggesting that they are due to diffusion of protein and glucose from interstitium into tubular fluid across the denuded basement membranes and that epithelial cells, under normal conditions, act as a barrier to diffusion of certain substances between the interstitium and tubular fluid." | 1.25 | The nature of D-serine--induced nephrotoxicity. ( Carone, FA; Ganote, CE; Peterson, DR, 1974) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (71.43) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 1 (14.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tudpor, K | 1 |
| Laínez, S | 1 |
| Kwakernaak, AJ | 1 |
| Kovalevskaya, NV | 1 |
| Verkaart, S | 1 |
| van Genesen, S | 1 |
| van der Kemp, A | 1 |
| Navis, G | 1 |
| Bindels, RJ | 1 |
| Hoenderop, JG | 1 |
| Williams, RE | 1 |
| Major, H | 1 |
| Lock, EA | 1 |
| Lenz, EM | 1 |
| Wilson, ID | 1 |
| Carone, FA | 3 |
| Ganote, CE | 2 |
| Nakamura, S | 1 |
| Goldman, B | 1 |
| Peterson, DR | 1 |
| Rubin, HM | 1 |
| Giorgio, AJ | 1 |
| Macdonald, RR | 1 |
| Linarelli, LG | 1 |
| Cuppage, FE | 1 |
| Tate, A | 1 |
7 other studies available for serine and Proteinuria
| Article | Year |
|---|---|
Urinary plasmin inhibits TRPV5 in nephrotic-range proteinuria.
Topics: Amino Acid Sequence; Base Sequence; Calcium; Calcium Signaling; Calmodulin; Fibrinolysin; HEK293 Cel | 2012 |
D-Serine-induced nephrotoxicity: a HPLC-TOF/MS-based metabonomics approach.
Topics: Animals; Chromatography, High Pressure Liquid; Glycosuria; Kidney; Kidney Tubular Necrosis, Acute; M | 2005 |
D-serine nephrotoxicity. The nature of proteinuria, glucosuria, and aminoaciduria in acute tubular necrosis.
Topics: Acute Kidney Injury; Animals; Glycosuria; Kidney Tubular Necrosis, Acute; Kidney Tubules; Male; Pota | 1975 |
Urinary loss of glucose, phosphate, and protein by diffusion into proximal straight tubules injured by D-serine and maleic acid.
Topics: Acute Kidney Injury; Animals; Carbon Radioisotopes; Glomerular Filtration Rate; Glucose; Glycosuria; | 1985 |
The nature of D-serine--induced nephrotoxicity.
Topics: Acute Kidney Injury; Animals; Cytoplasm; Diffusion; Epithelial Cells; Epithelium; Glycosuria; Kidney | 1974 |
Selective malabsorption of vitamin B 12: report of a case with metabolic studies.
Topics: Alanine; Amino Acids; Anemia, Macrocytic; Child; Chromatography, Gas; Glycine; Hemoglobins; Histidin | 1974 |
Repair of the nephron in acute renal failure: comparative regeneration following various forms of acute tubular injury.
Topics: Acute Kidney Injury; Animals; Chromates; Creatinine; Ischemia; Kidney Function Tests; Kidney Tubules | 1968 |