serine has been researched along with Precursor T-Cell Lymphoblastic Leukemia-Lymphoma in 6 studies
Serine: A non-essential amino acid occurring in natural form as the L-isomer. It is synthesized from GLYCINE or THREONINE. It is involved in the biosynthesis of PURINES; PYRIMIDINES; and other amino acids.
serine : An alpha-amino acid that is alanine substituted at position 3 by a hydroxy group.
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma: A leukemia/lymphoma found predominately in children and young adults and characterized LYMPHADENOPATHY and THYMUS GLAND involvement. It most frequently presents as a lymphoma, but a leukemic progression in the bone marrow is common.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Here, using human cancer cells and patient-derived xenografts in mice, we show that the cyclin D3-CDK6 kinase phosphorylates and inhibits the catalytic activity of two key enzymes in the glycolytic pathway, 6-phosphofructokinase and pyruvate kinase M2." | 1.46 | The metabolic function of cyclin D3-CDK6 kinase in cancer cell survival. ( Chick, JM; Dyson, NJ; Gao, H; Gao, X; Geng, Y; Gerdemann, U; Gygi, SP; Haining, WN; Keibler, MA; Nicolay, BN; Polyak, K; Ren, H; Roberts, TM; Sicinska, E; Sicinski, P; Suski, JM; Wang, H; Williams, JA; Yang, G, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 6 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, H | 1 |
| Nicolay, BN | 1 |
| Chick, JM | 1 |
| Gao, X | 1 |
| Geng, Y | 1 |
| Ren, H | 1 |
| Gao, H | 1 |
| Yang, G | 1 |
| Williams, JA | 1 |
| Suski, JM | 1 |
| Keibler, MA | 1 |
| Sicinska, E | 1 |
| Gerdemann, U | 1 |
| Haining, WN | 1 |
| Roberts, TM | 1 |
| Polyak, K | 1 |
| Gygi, SP | 1 |
| Dyson, NJ | 1 |
| Sicinski, P | 1 |
| Kampen, KR | 1 |
| Fancello, L | 1 |
| Girardi, T | 1 |
| Rinaldi, G | 1 |
| Planque, M | 1 |
| Sulima, SO | 1 |
| Loayza-Puch, F | 1 |
| Verbelen, B | 1 |
| Vereecke, S | 1 |
| Verbeeck, J | 1 |
| Op de Beeck, J | 1 |
| Royaert, J | 1 |
| Vermeersch, P | 1 |
| Cassiman, D | 1 |
| Cools, J | 1 |
| Agami, R | 1 |
| Fiers, M | 1 |
| Fendt, SM | 1 |
| De Keersmaecker, K | 1 |
| Luca, VC | 1 |
| Jude, KM | 1 |
| Pierce, NW | 1 |
| Nachury, MV | 1 |
| Fischer, S | 1 |
| Garcia, KC | 1 |
| Huang, Y | 1 |
| Thoms, JA | 1 |
| Tursky, ML | 1 |
| Knezevic, K | 1 |
| Beck, D | 1 |
| Chandrakanthan, V | 1 |
| Suryani, S | 1 |
| Olivier, J | 1 |
| Boulton, A | 1 |
| Glaros, EN | 1 |
| Thomas, SR | 1 |
| Lock, RB | 1 |
| MacKenzie, KL | 1 |
| Bushweller, JH | 1 |
| Wong, JW | 1 |
| Pimanda, JE | 1 |
| Marín-Rubio, JL | 1 |
| de Arriba, MC | 1 |
| Cobos-Fernández, MA | 1 |
| González-Sánchez, L | 1 |
| Ors, I | 1 |
| Sastre, I | 1 |
| Fernández-Piqueras, J | 1 |
| Villa-Morales, M | 1 |
| Li, Y | 1 |
| Deng, C | 1 |
| Hu, X | 1 |
| Patel, B | 1 |
| Fu, X | 1 |
| Qiu, Y | 1 |
| Brand, M | 1 |
| Zhao, K | 1 |
| Huang, S | 1 |
6 other studies available for serine and Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
| Article | Year |
|---|---|
The metabolic function of cyclin D3-CDK6 kinase in cancer cell survival.
Topics: Aminopyridines; Animals; Apoptosis; Cell Cycle; Cell Line, Tumor; Cell Survival; Cyclin D3; Cyclin-D | 2017 |
Translatome analysis reveals altered serine and glycine metabolism in T-cell acute lymphoblastic leukemia cells.
Topics: Animals; Cell Line; Gene Expression Profiling; Glycine; Mice; Mutation; Phosphoric Monoester Hydrola | 2019 |
Structural biology. Structural basis for Notch1 engagement of Delta-like 4.
Topics: Alagille Syndrome; Amino Acid Sequence; Amino Acid Substitution; Animals; Cell Line; Conserved Seque | 2015 |
MAPK/ERK2 phosphorylates ERG at serine 283 in leukemic cells and promotes stem cell signatures and cell proliferation.
Topics: Binding Sites; Cell Line, Tumor; Cell Proliferation; Hematopoietic Stem Cells; Humans; Leukemia; Leu | 2016 |
Deregulated FADD expression and phosphorylation in T-cell lymphoblastic lymphoma.
Topics: Animals; Apoptosis; Biomarkers, Tumor; Casein Kinase Ialpha; Cell Proliferation; Cytoplasm; DNA, Com | 2016 |
Dynamic interaction between TAL1 oncoprotein and LSD1 regulates TAL1 function in hematopoiesis and leukemogenesis.
Topics: Basic Helix-Loop-Helix Transcription Factors; Cell Line; Cyclic AMP-Dependent Protein Kinases; DNA M | 2012 |