Page last updated: 2024-11-08

serine and Porphyrias

serine has been researched along with Porphyrias in 3 studies

Serine: A non-essential amino acid occurring in natural form as the L-isomer. It is synthesized from GLYCINE or THREONINE. It is involved in the biosynthesis of PURINES; PYRIMIDINES; and other amino acids.
serine : An alpha-amino acid that is alanine substituted at position 3 by a hydroxy group.

Porphyrias: A diverse group of metabolic diseases characterized by errors in the biosynthetic pathway of HEME in the LIVER, the BONE MARROW, or both. They are classified by the deficiency of specific enzymes, the tissue site of enzyme defect, or the clinical features that include neurological (acute) or cutaneous (skin lesions). Porphyrias can be hereditary or acquired as a result of toxicity to the hepatic or erythropoietic marrow tissues.

Research Excerpts

ExcerptRelevanceReference
"Porphyria was induced in adult male Wistar rats starved for 24 hr by SC injection of 400 mg/kg allylisopropylacetamide (AIA)."3.67Endogenously formed norharman (beta-carboline) in platelet rich plasma obtained from porphyric rats. ( Bruinvels, J; Schouten, MJ, 1986)
"It was investigated whether an increased demand for glycine, as postulated to occur in patients who have suffered from episodic psychoses accompanied by multiple perceptual distortions, could evoke psychotic reactions."3.66Serine and glycine-induced catalepsy in porphyric rats: an animal model for psychosis? ( Bruinvels, J; Pepplinkhuizen, L; Schouten, MJ; Wilson, JH, 1983)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19903 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Pepplinkhuizen, L2
Bruinvels, J3
Blom, W1
Moleman, P1
Schouten, MJ2
Wilson, JH1

Other Studies

3 other studies available for serine and Porphyrias

ArticleYear
Schizophrenia-like psychosis caused by a metabolic disorder.
    Lancet (London, England), 1980, Mar-01, Volume: 1, Issue:8166

    Topics: Adolescent; Adult; Antipsychotic Agents; Diagnosis, Differential; Female; Glycine; Humans; Porphyria

1980
Serine and glycine-induced catalepsy in porphyric rats: an animal model for psychosis?
    Pharmacology, biochemistry, and behavior, 1983, Volume: 19, Issue:2

    Topics: Allylisopropylacetamide; Aminolevulinic Acid; Animals; Catalepsy; Disease Models, Animal; Glycine; H

1983
Endogenously formed norharman (beta-carboline) in platelet rich plasma obtained from porphyric rats.
    Pharmacology, biochemistry, and behavior, 1986, Volume: 24, Issue:5

    Topics: Alkaloids; Allylisopropylacetamide; Aminolevulinic Acid; Animals; Blood Platelets; Carbolines; Catal

1986