serine has been researched along with Polycystic Ovary Syndrome in 12 studies
Serine: A non-essential amino acid occurring in natural form as the L-isomer. It is synthesized from GLYCINE or THREONINE. It is involved in the biosynthesis of PURINES; PYRIMIDINES; and other amino acids.
serine : An alpha-amino acid that is alanine substituted at position 3 by a hydroxy group.
Polycystic Ovary Syndrome: A complex disorder characterized by infertility, HIRSUTISM; OBESITY; and various menstrual disturbances such as OLIGOMENORRHEA; AMENORRHEA; ANOVULATION. Polycystic ovary syndrome is usually associated with bilateral enlarged ovaries studded with atretic follicles, not with cysts. The term, polycystic ovary, is misleading.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The data demonstrated an interaction between testosterone and insulin on phosphorylation of intracellular signaling proteins, and suggests a link between a hyperandrogenic, hyperinsulinemic environment and the development of insulin resistance involving serine phosphorylation of IRS-1 Ser(636/639)." | 3.75 | Effect of testosterone on insulin stimulated IRS1 Ser phosphorylation in primary rat myotubes--a potential model for PCOS-related insulin resistance. ( Allemand, MC; Asmann, YW; Coddington, CC; Irving, BA; Klaus, KA; Nair, KS; Tatpati, L, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (16.67) | 18.2507 |
| 2000's | 6 (50.00) | 29.6817 |
| 2010's | 3 (25.00) | 24.3611 |
| 2020's | 1 (8.33) | 2.80 |
| Authors | Studies |
|---|---|
| Gao, L | 1 |
| Wang, S | 1 |
| Xu, J | 2 |
| Lu, D | 1 |
| Cui, Y | 1 |
| Fu, L | 1 |
| Zhang, Z | 1 |
| Zhang, A | 1 |
| Huang, X | 1 |
| Zheng, Q | 1 |
| Cao, Y | 1 |
| Wang, L | 1 |
| Du, J | 1 |
| Tepavčević, S | 1 |
| Milutinović, DV | 1 |
| Macut, D | 1 |
| Stanišić, J | 1 |
| Nikolić, M | 1 |
| Božić-Antić, I | 1 |
| Rodaljević, S | 1 |
| Bjekić-Macut, J | 1 |
| Matić, G | 1 |
| Korićanac, G | 1 |
| Allemand, MC | 1 |
| Irving, BA | 1 |
| Asmann, YW | 1 |
| Klaus, KA | 1 |
| Tatpati, L | 1 |
| Coddington, CC | 1 |
| Nair, KS | 1 |
| Hemmings, KE | 1 |
| Maruthini, D | 1 |
| Vyjayanthi, S | 1 |
| Hogg, JE | 1 |
| Balen, AH | 1 |
| Campbell, BK | 1 |
| Leese, HJ | 1 |
| Picton, HM | 1 |
| Miller, WL | 4 |
| Seow, KM | 1 |
| Juan, CC | 1 |
| Hsu, YP | 1 |
| Hwang, JL | 1 |
| Huang, LW | 1 |
| Ho, LT | 1 |
| Théron-Gérard, L | 1 |
| Pasquier, M | 1 |
| Czernichow, C | 1 |
| Cédrin-Durnerin, I | 1 |
| Hugues, JN | 1 |
| Bremer, AA | 1 |
| Zhang, LH | 1 |
| Rodriguez, H | 1 |
| Ohno, S | 1 |
| Moghrabi, N | 1 |
| Hughes, IA | 1 |
| Dunaif, A | 1 |
| Andersson, S | 1 |
4 reviews available for serine and Polycystic Ovary Syndrome
| Article | Year |
|---|---|
Androgen biosynthesis from cholesterol to DHEA.
Topics: Adrenal Glands; Adrenal Hyperplasia, Congenital; Androgens; Animals; Cholesterol; Cholesterol Side-C | 2002 |
Disorders of androgen synthesis--from cholesterol to dehydroepiandrosterone.
Topics: Adrenal Cortex; Adrenal Hyperplasia, Congenital; Androgens; Cholesterol; Cholesterol Side-Chain Clea | 2005 |
[Follicle-stimulating hormone receptor polymorphism and ovarian function].
Topics: Codon; Female; Follicle Stimulating Hormone; Gene Frequency; Humans; Infertility, Female; Ovary; Pol | 2007 |
The serine phosphorylation hypothesis of polycystic ovary syndrome: a unifying mechanism for hyperandrogenemia and insulin resistance.
Topics: Androgens; Female; Gonadotropins; Humans; Insulin Resistance; Phosphorylation; Polycystic Ovary Synd | 2008 |
8 other studies available for serine and Polycystic Ovary Syndrome
| Article | Year |
|---|---|
SET improved oocyte maturation by serine/threonine protein phosphatase 2A and inhibited oocyte apoptosis in mouse oocytes.
Topics: Animals; Apoptosis; Female; Humans; Mice; Mice, Inbred ICR; Oocytes; Polycystic Ovary Syndrome; Prot | 2022 |
Association study between FSHR Ala307Thr and Ser680Asn variants and polycystic ovary syndrome (PCOS) in Northern Chinese Han women.
Topics: Adult; Alanine; Amino Acid Substitution; Asian People; Asparagine; Case-Control Studies; China; Fema | 2013 |
Cardiac Nitric Oxide Synthases and Na⁺/K⁺-ATPase in the Rat Model of Polycystic Ovary Syndrome Induced by Dihydrotestosterone.
Topics: Animals; Cell Membrane; Dihydrotestosterone; Disease Models, Animal; Down-Regulation; Female; Myocar | 2015 |
Effect of testosterone on insulin stimulated IRS1 Ser phosphorylation in primary rat myotubes--a potential model for PCOS-related insulin resistance.
Topics: Animals; Cell Differentiation; Female; Insulin; Insulin Resistance; Muscle Fibers, Skeletal; Muscle, | 2009 |
Amino acid turnover by human oocytes is influenced by gamete developmental competence, patient characteristics and gonadotrophin treatment.
Topics: Age Factors; Alanine; Amino Acids; Arginine; Chorionic Gonadotropin; Chromatography, High Pressure L | 2013 |
Amelioration of insulin resistance in women with PCOS via reduced insulin receptor substrate-1 Ser312 phosphorylation following laparoscopic ovarian electrocautery.
Topics: Body Mass Index; Electrocoagulation; Female; Glucose Tolerance Test; Humans; Insulin Receptor Substr | 2007 |
Serine phosphorylation of human P450c17 increases 17,20-lyase activity: implications for adrenarche and the polycystic ovary syndrome.
Topics: Adrenal Cortex; Age Factors; Aldehyde-Lyases; Amino Acids; Cyclic AMP-Dependent Protein Kinases; Cyt | 1995 |
Deleterious missense mutations and silent polymorphism in the human 17beta-hydroxysteroid dehydrogenase 3 gene (HSD17B3).
Topics: 17-Hydroxysteroid Dehydrogenases; Adolescent; Base Composition; Child; Disorders of Sex Development; | 1998 |