serine has been researched along with Polycystic Kidney, Autosomal Dominant in 2 studies
Serine: A non-essential amino acid occurring in natural form as the L-isomer. It is synthesized from GLYCINE or THREONINE. It is involved in the biosynthesis of PURINES; PYRIMIDINES; and other amino acids.
serine : An alpha-amino acid that is alanine substituted at position 3 by a hydroxy group.
Polycystic Kidney, Autosomal Dominant: Kidney disorders with autosomal dominant inheritance and characterized by multiple CYSTS in both KIDNEYS with progressive deterioration of renal function.
| Excerpt | Relevance | Reference |
|---|---|---|
| "ADPKD is associated with significant morbidity, and is a major underlying cause of end-stage renal failure (ESRF)." | 1.36 | Carboxy terminal tail of polycystin-1 regulates localization of TSC2 to repress mTOR. ( Dere, R; Sandford, RN; Walker, CL; Wilson, PD, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dere, R | 1 |
| Wilson, PD | 1 |
| Sandford, RN | 1 |
| Walker, CL | 1 |
| Chernova, MN | 1 |
| Vandorpe, DH | 1 |
| Clark, JS | 1 |
| Alper, SL | 1 |
2 other studies available for serine and Polycystic Kidney, Autosomal Dominant
| Article | Year |
|---|---|
Carboxy terminal tail of polycystin-1 regulates localization of TSC2 to repress mTOR.
Topics: 14-3-3 Proteins; Adult; Cell Line; Humans; Immunoblotting; Immunohistochemistry; Intracellular Signa | 2010 |
Expression of the polycystin-1 C-terminal cytoplasmic tail increases Cl channel activity in Xenopus oocytes.
Topics: Animals; Calcium; Cations; Cell Membrane; Chloride Channels; Chlorides; Cytoplasm; Membrane Proteins | 2005 |