serine has been researched along with Pheochromocytoma, Extra-Adrenal in 9 studies
Serine: A non-essential amino acid occurring in natural form as the L-isomer. It is synthesized from GLYCINE or THREONINE. It is involved in the biosynthesis of PURINES; PYRIMIDINES; and other amino acids.
serine : An alpha-amino acid that is alanine substituted at position 3 by a hydroxy group.
| Excerpt | Relevance | Reference |
|---|---|---|
| " We investigated the effect of LB1, a small molecule inhibitor of serine/threonine protein phosphatase 2A (PP2A), on its ability to inhibit a low growth fraction and highly drug-resistant solid neuroendocrine tumor, such as metastatic pheochromocytoma (PHEO)." | 3.77 | Pharmacologic modulation of serine/threonine phosphorylation highly sensitizes PHEO in a MPC cell and mouse model to conventional chemotherapy. ( Bernardo, M; Chiang, J; Lonser, R; Lu, J; Martiniova, L; Pacak, K; Zhuang, Z, 2011) |
| "S891A mutation caused medullary thyroid cancer (MTC) in 69." | 1.36 | The clinical spectrum of multiple endocrine neoplasia type 2a caused by the rare intracellular RET mutation S891A. ( Aylwin, S; Beck-Peccoz, P; Diaz-Cano, S; Dralle, H; Fugazzola, L; Izatt, L; Machens, A; McGregor, A; Schulte, KM; Talat, N, 2010) |
| "All MEN 2A affected family members suffered from medullary thyroid carcinoma and two of ten patients for pheochromocytoma." | 1.33 | Novel germline mutation in the transmembrane region of RET gene close to Cys634Ser mutation associated with MEN 2A syndrome. ( Altaner, C; Altanerova, V; Breza, J; Kostalova, L; Poturnajova, M, 2005) |
| "The observed constellation of microcephaly, deafness, cryptorchidism, developmental delay, hypertension, and bilateral pheochromocytoma in association with a VHL mutation A451G in a patient with negative family history has not previously been described in the literature." | 1.32 | Bilateral pheochromocytomas and congenital anomalies associated with a de novo germline mutation in the von Hippel-Lindau gene. ( Assadi, F; Brackbill, EL, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (22.22) | 18.7374 |
| 1990's | 3 (33.33) | 18.2507 |
| 2000's | 2 (22.22) | 29.6817 |
| 2010's | 2 (22.22) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Schulte, KM | 1 |
| Machens, A | 1 |
| Fugazzola, L | 1 |
| McGregor, A | 1 |
| Diaz-Cano, S | 1 |
| Izatt, L | 1 |
| Aylwin, S | 1 |
| Talat, N | 1 |
| Beck-Peccoz, P | 1 |
| Dralle, H | 1 |
| Martiniova, L | 1 |
| Lu, J | 1 |
| Chiang, J | 1 |
| Bernardo, M | 1 |
| Lonser, R | 1 |
| Zhuang, Z | 1 |
| Pacak, K | 1 |
| Assadi, F | 1 |
| Brackbill, EL | 1 |
| Poturnajova, M | 1 |
| Altanerova, V | 1 |
| Kostalova, L | 1 |
| Breza, J | 1 |
| Altaner, C | 1 |
| Haycock, JW | 1 |
| Mitchell, JP | 1 |
| Hardie, DG | 1 |
| Vulliet, PR | 1 |
| Miyasaka, T | 1 |
| Miyasaka, J | 1 |
| Saltiel, AR | 1 |
| Gonzalez, GA | 1 |
| Montminy, MR | 1 |
| Pigeon, D | 1 |
| Ferrara, P | 1 |
| Gros, F | 1 |
| Thibault, J | 1 |
9 other studies available for serine and Pheochromocytoma, Extra-Adrenal
| Article | Year |
|---|---|
The clinical spectrum of multiple endocrine neoplasia type 2a caused by the rare intracellular RET mutation S891A.
Topics: Adolescent; Adrenal Gland Neoplasms; Adult; Aged; Aged, 80 and over; Alanine; Amino Acid Substitutio | 2010 |
Pharmacologic modulation of serine/threonine phosphorylation highly sensitizes PHEO in a MPC cell and mouse model to conventional chemotherapy.
Topics: Adrenal Gland Neoplasms; Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; | 2011 |
Bilateral pheochromocytomas and congenital anomalies associated with a de novo germline mutation in the von Hippel-Lindau gene.
Topics: Adrenal Gland Neoplasms; Amino Acid Substitution; Child; Cryptorchidism; Developmental Disabilities; | 2003 |
Novel germline mutation in the transmembrane region of RET gene close to Cys634Ser mutation associated with MEN 2A syndrome.
Topics: Adrenal Gland Neoplasms; Carcinoma, Medullary; Cysteine; Exons; Female; Gene Frequency; Genetic Link | 2005 |
Phosphorylation of tyrosine hydroxylase in situ at serine 8, 19, 31, and 40.
Topics: Adrenal Gland Neoplasms; Amino Acid Sequence; Animals; Cell Line; Chromatography, High Pressure Liqu | 1990 |
Site-specific phosphorylation of tyrosine hydroxylase after KCl depolarization and nerve growth factor treatment of PC12 cells.
Topics: Adrenal Gland Neoplasms; Animals; Cell Line; Cell Membrane; Chromatography, High Pressure Liquid; Is | 1990 |
Okadaic acid stimulates the activity of microtubule associated protein kinase in PC-12 pheochromocytoma cells.
Topics: Adrenal Gland Neoplasms; Animals; Brain; Calcium-Calmodulin-Dependent Protein Kinases; Epidermal Gro | 1990 |
Cyclic AMP stimulates somatostatin gene transcription by phosphorylation of CREB at serine 133.
Topics: Adrenal Gland Neoplasms; Amino Acid Sequence; Animals; Base Sequence; Cell Line; Colforsin; Cyclic A | 1989 |
Rat pheochromocytoma tyrosine hydroxylase is phosphorylated on serine 40 by an associated protein kinase.
Topics: Amino Acid Sequence; Animals; Electrophoresis, Polyacrylamide Gel; Peptide Fragments; Pheochromocyto | 1987 |