serine has been researched along with Peutz-Jeghers Syndrome in 3 studies
Serine: A non-essential amino acid occurring in natural form as the L-isomer. It is synthesized from GLYCINE or THREONINE. It is involved in the biosynthesis of PURINES; PYRIMIDINES; and other amino acids.
serine : An alpha-amino acid that is alanine substituted at position 3 by a hydroxy group.
Peutz-Jeghers Syndrome: A hereditary disease caused by autosomal dominant mutations involving CHROMOSOME 19. It is characterized by the presence of INTESTINAL POLYPS, consistently in the JEJUNUM, and mucocutaneous pigmentation with MELANIN spots of the lips, buccal MUCOSA, and digits.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In this review, we summarize layers of evidence demonstrating that disordered metabolisms in glucose, glutamine, lipid, and serine caused by LKB1 deficiency promote carcinogenesis and non-neoplastic diseases." | 5.12 | LKB1 deficiency-induced metabolic reprogramming in tumorigenesis and non-neoplastic diseases. ( Meng, Q; Sun, Q; Wang, Y; Xu, ZX; Zhang, Y; Zhou, H, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Zhang, Y | 1 |
| Meng, Q | 1 |
| Sun, Q | 1 |
| Xu, ZX | 1 |
| Zhou, H | 1 |
| Wang, Y | 1 |
| Gao, Y | 1 |
| Zhang, FM | 1 |
| Huang, S | 1 |
| Wang, X | 1 |
| Zhang, P | 1 |
| Huang, XD | 1 |
| Ji, GZ | 1 |
| Fan, ZN | 1 |
| Sapkota, GP | 1 |
| Kieloch, A | 1 |
| Lizcano, JM | 1 |
| Lain, S | 1 |
| Arthur, JS | 1 |
| Williams, MR | 1 |
| Morrice, N | 1 |
| Deak, M | 1 |
| Alessi, DR | 1 |
1 review available for serine and Peutz-Jeghers Syndrome
| Article | Year |
|---|---|
LKB1 deficiency-induced metabolic reprogramming in tumorigenesis and non-neoplastic diseases.
Topics: AMP-Activated Protein Kinase Kinases; AMP-Activated Protein Kinases; Animals; Apoptosis; Carcinogene | 2021 |
2 other studies available for serine and Peutz-Jeghers Syndrome
| Article | Year |
|---|---|
A De Novo mutation of STK11 gene in a Chinese patient with Peutz-Jeghers syndrome.
Topics: Adult; Alleles; Amino Acid Substitution; AMP-Activated Protein Kinase Kinases; Biopsy; China; Codon; | 2010 |
Phosphorylation of the protein kinase mutated in Peutz-Jeghers cancer syndrome, LKB1/STK11, at Ser431 by p90(RSK) and cAMP-dependent protein kinase, but not its farnesylation at Cys(433), is essential for LKB1 to suppress cell vrowth.
Topics: AMP-Activated Protein Kinase Kinases; AMP-Activated Protein Kinases; Animals; Binding Sites; Calcium | 2001 |