serine has been researched along with Neurofibromatosis 2 in 2 studies
Serine: A non-essential amino acid occurring in natural form as the L-isomer. It is synthesized from GLYCINE or THREONINE. It is involved in the biosynthesis of PURINES; PYRIMIDINES; and other amino acids.
serine : An alpha-amino acid that is alanine substituted at position 3 by a hydroxy group.
Neurofibromatosis 2: An autosomal dominant disorder characterized by a high incidence of bilateral acoustic neuromas as well as schwannomas (NEURILEMMOMA) of other cranial and peripheral nerves, and other benign intracranial tumors including meningiomas, ependymomas, spinal neurofibromas, and gliomas. The disease has been linked to mutations of the NF2 gene (GENES, NEUROFIBROMATOSIS 2) on chromosome 22 (22q12) and usually presents clinically in the first or second decade of life.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Merlin, the product of the Neurofibromatosis type 2 (NF2) tumor suppressor gene, belongs to the ezrin-radixin-moesin (ERM) subgroup of the protein 4." | 1.33 | Evolution and origin of merlin, the product of the Neurofibromatosis type 2 (NF2) tumor-suppressor gene. ( Akhmametyeva, EM; Blinov, A; Chang, LS; Golovnina, K; Omelyanchuk, LV, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Rong, R | 1 |
| Surace, EI | 1 |
| Haipek, CA | 1 |
| Gutmann, DH | 1 |
| Ye, K | 1 |
| Golovnina, K | 1 |
| Blinov, A | 1 |
| Akhmametyeva, EM | 1 |
| Omelyanchuk, LV | 1 |
| Chang, LS | 1 |
2 other studies available for serine and Neurofibromatosis 2
| Article | Year |
|---|---|
Serine 518 phosphorylation modulates merlin intramolecular association and binding to critical effectors important for NF2 growth suppression.
Topics: Animals; Carrier Proteins; Endosomal Sorting Complexes Required for Transport; Humans; Hyaluronan Re | 2004 |
Evolution and origin of merlin, the product of the Neurofibromatosis type 2 (NF2) tumor-suppressor gene.
Topics: Actins; Amino Acid Sequence; Animals; Binding Sites; Ciona intestinalis; Computational Biology; Dros | 2005 |