serine has been researched along with Necrosis in 22 studies
Serine: A non-essential amino acid occurring in natural form as the L-isomer. It is synthesized from GLYCINE or THREONINE. It is involved in the biosynthesis of PURINES; PYRIMIDINES; and other amino acids.
serine : An alpha-amino acid that is alanine substituted at position 3 by a hydroxy group.
Necrosis: The death of cells in an organ or tissue due to disease, injury or failure of the blood supply.
| Excerpt | Relevance | Reference |
|---|---|---|
| "D-Serine causes selective necrosis to the straight portion of the rat renal proximal tubules." | 3.73 | Sodium benzoate attenuates D-serine induced nephrotoxicity in the rat. ( Lock, EA; Williams, RE, 2005) |
| " d-Serine injures the rat kidney, causing selective necrosis of the proximal straight tubules." | 3.72 | 1H NMR pattern recognition and 31P NMR studies with d-Serine in rat urine and kidney, time- and dose-related metabolic effects. ( Jacobsen, M; Lock, EA; Williams, RE, 2003) |
| "Co-treatment with calpain and serine/threonine phosphatase inhibitors restored pCREB levels and rescued neurons." | 1.31 | Oxidative stress induces neuronal death by recruiting a protease and phosphatase-gated mechanism. ( Loeffler, JP; Sée, V, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (18.18) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 8 (36.36) | 29.6817 |
| 2010's | 9 (40.91) | 24.3611 |
| 2020's | 1 (4.55) | 2.80 |
| Authors | Studies |
|---|---|
| Seo, J | 1 |
| Kim, Y | 1 |
| Ji, S | 1 |
| Kim, HB | 1 |
| Jung, H | 1 |
| Yi, EC | 1 |
| Lee, YH | 1 |
| Shin, I | 1 |
| Yang, WH | 1 |
| Cho, JW | 1 |
| Dondelinger, Y | 1 |
| Delanghe, T | 1 |
| Rojas-Rivera, D | 1 |
| Priem, D | 1 |
| Delvaeye, T | 1 |
| Bruggeman, I | 1 |
| Van Herreweghe, F | 1 |
| Vandenabeele, P | 1 |
| Bertrand, MJM | 1 |
| Zhan, L | 1 |
| Lu, Z | 1 |
| Zhu, X | 1 |
| Xu, W | 1 |
| Li, L | 1 |
| Li, X | 2 |
| Chen, S | 1 |
| Sun, W | 1 |
| Xu, E | 1 |
| Gong, W | 1 |
| Wang, H | 1 |
| Li, T | 1 |
| Attri, KS | 1 |
| Lewis, RE | 1 |
| Kalil, AC | 1 |
| Bhinderwala, F | 1 |
| Powers, R | 1 |
| Yin, G | 1 |
| Herring, LE | 1 |
| Asara, JM | 1 |
| Lei, YL | 1 |
| Yang, X | 1 |
| Rodriguez, DA | 1 |
| Yang, M | 1 |
| Green, DR | 1 |
| Singh, PK | 1 |
| Wen, H | 1 |
| Dashzeveg, N | 1 |
| Taira, N | 1 |
| Lu, ZG | 1 |
| Kimura, J | 1 |
| Yoshida, K | 1 |
| Joniova, J | 1 |
| Misuth, M | 1 |
| Sureau, F | 1 |
| Miskovsky, P | 1 |
| Nadova, Z | 1 |
| Zhang, Y | 1 |
| Su, SS | 1 |
| Zhao, S | 1 |
| Yang, Z | 1 |
| Zhong, CQ | 1 |
| Chen, X | 1 |
| Cai, Q | 1 |
| Yang, ZH | 1 |
| Huang, D | 1 |
| Wu, R | 1 |
| Han, J | 1 |
| Cook, N | 1 |
| Fraser, SA | 1 |
| Katerelos, M | 1 |
| Katsis, F | 1 |
| Gleich, K | 1 |
| Mount, PF | 1 |
| Steinberg, GR | 1 |
| Levidiotis, V | 1 |
| Kemp, BE | 1 |
| Power, DA | 1 |
| Qian, J | 1 |
| Ren, X | 1 |
| Wang, X | 1 |
| Zhang, P | 1 |
| Jones, WK | 1 |
| Molkentin, JD | 1 |
| Fan, GC | 1 |
| Kranias, EG | 1 |
| Linares-Palomino, J | 1 |
| Husainy, MA | 1 |
| Lai, VK | 1 |
| Dickenson, JM | 1 |
| Galiñanes, M | 1 |
| Rennier, K | 1 |
| Ji, JY | 1 |
| Lee, YS | 1 |
| Dayma, Y | 1 |
| Park, MY | 1 |
| Kim, KI | 1 |
| Yoo, SE | 1 |
| Kim, E | 1 |
| Cheng, WH | 1 |
| Zheng, X | 1 |
| Quimby, FR | 1 |
| Roneker, CA | 1 |
| Lei, XG | 1 |
| WACHSTEIN, M | 1 |
| BESEN, M | 1 |
| TAPP, E | 1 |
| CARROLL, R | 1 |
| KOVACS, K | 1 |
| Williams, RE | 2 |
| Jacobsen, M | 1 |
| Lock, EA | 2 |
| Hori, K | 1 |
| Saito, S | 1 |
| Sée, V | 1 |
| Loeffler, JP | 1 |
| Stoffel, M | 1 |
| Plesnila, N | 1 |
| Eriskat, J | 1 |
| Fürst, M | 1 |
| Baethmann, A | 1 |
| Kaltenbach, JP | 1 |
| Ganote, CE | 1 |
| Carone, FA | 1 |
| Samofalova, MS | 1 |
22 other studies available for serine and Necrosis
| Article | Year |
|---|---|
Topics: Animals; Apoptosis; Erythrocytes; Humans; Mice; Necroptosis; Necrosis; Receptor-Interacting Protein | 2023 |
MK2 phosphorylation of RIPK1 regulates TNF-mediated cell death.
Topics: Animals; Apoptosis; Cell Line; Cytosol; Disease Models, Animal; Enzyme Activation; Female; Fibroblas | 2017 |
Hypoxic preconditioning attenuates necroptotic neuronal death induced by global cerebral ischemia via Drp1-dependent signaling pathway mediated by CaMKIIα inactivation in adult rats.
Topics: Animals; Apoptosis; Brain Ischemia; CA1 Region, Hippocampal; Calcium-Calmodulin-Dependent Protein Ki | 2019 |
O-GlcNAc Transferase Suppresses Inflammation and Necroptosis by Targeting Receptor-Interacting Serine/Threonine-Protein Kinase 3.
Topics: Animals; Apoptosis; Cell Line; Glucose; Humans; Immunity, Innate; Inflammation; Mice; Mice, Inbred C | 2019 |
Palmdelphin, a novel target of p53 with Ser46 phosphorylation, controls cell death in response to DNA damage.
Topics: Adenosine Triphosphate; Apoptosis; Cell Line, Tumor; Cell Nucleus; DNA Damage; Gene Expression Regul | 2014 |
Effect of PKCα expression on Bcl-2 phosphorylation and cell death by hypericin.
Topics: Anthracenes; Apoptosis; Cell Line, Tumor; Cell Survival; Gene Expression; Humans; Mitochondria; Necr | 2014 |
RIP1 autophosphorylation is promoted by mitochondrial ROS and is essential for RIP3 recruitment into necrosome.
Topics: Animals; Apoptosis; Cell Line, Tumor; Cysteine; Humans; Mice; Mitochondria; Necrosis; NIH 3T3 Cells; | 2017 |
Low salt concentrations activate AMP-activated protein kinase in mouse macula densa cells.
Topics: Acetyl-CoA Carboxylase; AMP-Activated Protein Kinases; Animals; Apoptosis; Benzimidazoles; Bumetanid | 2009 |
Blockade of Hsp20 phosphorylation exacerbates cardiac ischemia/reperfusion injury by suppressed autophagy and increased cell death.
Topics: Alanine; Animals; Apoptosis; Autophagy; Base Sequence; Disease Models, Animal; Heart Failure; HSP20 | 2009 |
Selective blockade of protein kinase B protects the rat and human myocardium against ischaemic injury.
Topics: Adult; Aged; Aged, 80 and over; Animals; Apoptosis; Creatine Kinase; Dose-Response Relationship, Dru | 2010 |
Shear stress regulates expression of death-associated protein kinase in suppressing TNFα-induced endothelial apoptosis.
Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; Calcium-Calmodulin-Dependent Protein Kinases; Cas | 2012 |
Daxx is a key downstream component of receptor interacting protein kinase 3 mediating retinal ischemic cell death.
Topics: Animals; Carrier Proteins; Cell Line; Co-Repressor Proteins; Intracellular Signaling Peptides and Pr | 2013 |
Low levels of glutathione peroxidase 1 activity in selenium-deficient mouse liver affect c-Jun N-terminal kinase activation and p53 phosphorylation on Ser-15 in pro-oxidant-induced aponecrosis.
Topics: Animals; DNA; Enzyme Activation; Glutathione Peroxidase; Glutathione Peroxidase GPX1; Herbicides; JN | 2003 |
ELECTRON MICROSCOPY OF RENAL COAGULATIVE NECROSIS DUE TO DL-SERINE, WITH SPECIAL REFERENCE TO MITOCHONDRIAL PYKNOSIS.
Topics: Electrons; Injections, Intravenous; Kidney Diseases; Microscopy; Microscopy, Electron; Mitochondria; | 1964 |
TETRACYCLINE FLUORESCENCE IN EXPERIMENTAL RENAL LESIONS.
Topics: Ammonium Compounds; Chlorides; Fluorescence; Heparin Antagonists; Ischemia; Kidney; Kidney Diseases; | 1965 |
1H NMR pattern recognition and 31P NMR studies with d-Serine in rat urine and kidney, time- and dose-related metabolic effects.
Topics: Animals; Dose-Response Relationship, Drug; Kidney; Lactic Acid; Magnetic Resonance Spectroscopy; Mal | 2003 |
Induction of tumour blood flow stasis and necrosis: a new function for epinephrine similar to that of combretastatin A-4 derivative AVE8062 (AC7700).
Topics: Animals; Antineoplastic Agents, Phytogenic; Catecholamines; Epinephrine; Necrosis; Neoplasms, Experi | 2004 |
Sodium benzoate attenuates D-serine induced nephrotoxicity in the rat.
Topics: Animals; Creatinine; D-Amino-Acid Oxidase; Disease Models, Animal; Dose-Response Relationship, Drug; | 2005 |
Oxidative stress induces neuronal death by recruiting a protease and phosphatase-gated mechanism.
Topics: Animals; Apoptosis; Calcineurin; Calcium-Calmodulin-Dependent Protein Kinases; Calpain; Caspases; Cy | 2001 |
Release of excitatory amino acids in the penumbra of a focal cortical necrosis.
Topics: Alanine; Animals; Aspartic Acid; Cerebral Cortex; Excitatory Amino Acids; Glutamic Acid; Glycine; Ma | 2002 |
Renal tubular necrosis induced by compounds structurally related to D-serine.
Topics: Acute Kidney Injury; Animals; Kidney Tubular Necrosis, Acute; Kidney Tubules, Proximal; Male; Necros | 1979 |
[Levels of free amino acids in the blood and heart muscle in the human at various periods of myocardial infarct (clinical anatomical parallels)].
Topics: Alanine; Amino Acids; Arginine; Aspartic Acid; Chromatography; Erythrocytes; Glutamates; Glycine; Hi | 1968 |