serine has been researched along with Myocardial Ischemia in 13 studies
Serine: A non-essential amino acid occurring in natural form as the L-isomer. It is synthesized from GLYCINE or THREONINE. It is involved in the biosynthesis of PURINES; PYRIMIDINES; and other amino acids.
serine : An alpha-amino acid that is alanine substituted at position 3 by a hydroxy group.
Myocardial Ischemia: A disorder of cardiac function caused by insufficient blood flow to the muscle tissue of the heart. The decreased blood flow may be due to narrowing of the coronary arteries (CORONARY ARTERY DISEASE), to obstruction by a thrombus (CORONARY THROMBOSIS), or less commonly, to diffuse narrowing of arterioles and other small vessels within the heart. Severe interruption of the blood supply to the myocardial tissue may result in necrosis of cardiac muscle (MYOCARDIAL INFARCTION).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Leonurine has been shown to have excellent anti-myocardial ischemia effects." | 8.12 | Cardioprotective Mechanism of Leonurine against Myocardial Ischemia through a Liver-Cardiac Crosstalk Metabolomics Study. ( Li, J; Lu, Q; Pan, D; Rong, W; Wang, A; Wang, L; Zhang, Y; Zhou, Q; Zhu, Q; Zhu, Y, 2022) |
| "Leonurine has been shown to have excellent anti-myocardial ischemia effects." | 4.12 | Cardioprotective Mechanism of Leonurine against Myocardial Ischemia through a Liver-Cardiac Crosstalk Metabolomics Study. ( Li, J; Lu, Q; Pan, D; Rong, W; Wang, A; Wang, L; Zhang, Y; Zhou, Q; Zhu, Q; Zhu, Y, 2022) |
| " Male Wistar rats (weighing 300-350 g) were assigned to the following groups: (1) sham, (2) myocardial ischemia vehicle-treated (MI-V), and (3) myocardial ischemia clofibrate-treated." | 3.81 | PPARα Stimulation Modulates Myocardial Ischemia-induced Activation of Renin-Angiotensin System. ( Cervantes-Pérez, LG; del Valle-Mondragón, L; Hong, E; Ibarra-Lara, L; Pastelín-Hernández, GS; Pérez-Severiano, F; Ramírez-Ortega, M; Sánchez-Aguilar, M; Sánchez-Mendoza, A; Soria-Castro, E; Torres-Narváez, JC, 2015) |
| "Treatment with rotigaptide significantly increased the time to ischemia-induced asystole and suppressed dephosphorylation of Ser297 and Ser368 at 30 min of ischemia." | 1.33 | Identification of ischemia-regulated phosphorylation sites in connexin43: A possible target for the antiarrhythmic peptide analogue rotigaptide (ZP123). ( Andersen, S; Axelsen, LN; Hennan, JK; Holstein-Rathlou, NH; Jensen, ON; Kjølbye, AL; Larsen, BD; Mohammed, S; Nielsen, MS; Stahlhut, M, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (7.69) | 18.2507 |
| 2000's | 6 (46.15) | 29.6817 |
| 2010's | 5 (38.46) | 24.3611 |
| 2020's | 1 (7.69) | 2.80 |
| Authors | Studies |
|---|---|
| Rong, W | 1 |
| Li, J | 1 |
| Pan, D | 1 |
| Zhou, Q | 1 |
| Zhang, Y | 2 |
| Lu, Q | 1 |
| Wang, L | 1 |
| Wang, A | 1 |
| Zhu, Y | 1 |
| Zhu, Q | 1 |
| Tang, B | 1 |
| Ma, J | 1 |
| Ha, X | 1 |
| Xing, Y | 1 |
| Ibarra-Lara, L | 1 |
| Sánchez-Aguilar, M | 1 |
| Hong, E | 1 |
| del Valle-Mondragón, L | 1 |
| Soria-Castro, E | 1 |
| Pérez-Severiano, F | 1 |
| Torres-Narváez, JC | 1 |
| Ramírez-Ortega, M | 1 |
| Pastelín-Hernández, GS | 1 |
| Cervantes-Pérez, LG | 1 |
| Sánchez-Mendoza, A | 1 |
| Borai, A | 1 |
| Livingstone, C | 1 |
| Ghayour-Mobarhan, M | 1 |
| Abuosa, A | 1 |
| Shafi, S | 1 |
| Mehta, S | 1 |
| Heidari, A | 1 |
| Emadzadeh, A | 1 |
| Wark, G | 1 |
| Ferns, G | 1 |
| Lv, L | 1 |
| Jiang, SS | 1 |
| Xu, J | 1 |
| Gong, JB | 1 |
| Cheng, Y | 1 |
| Respress, JL | 1 |
| van Oort, RJ | 1 |
| Li, N | 1 |
| Rolim, N | 1 |
| Dixit, SS | 1 |
| deAlmeida, A | 1 |
| Voigt, N | 1 |
| Lawrence, WS | 1 |
| Skapura, DG | 1 |
| Skårdal, K | 1 |
| Wisløff, U | 1 |
| Wieland, T | 1 |
| Ai, X | 1 |
| Pogwizd, SM | 1 |
| Dobrev, D | 1 |
| Wehrens, XH | 1 |
| Shi, Y | 1 |
| Baker, JE | 1 |
| Zhang, C | 1 |
| Tweddell, JS | 1 |
| Su, J | 1 |
| Pritchard, KA | 1 |
| Bonafé, M | 1 |
| Salvioli, S | 1 |
| Barbi, C | 1 |
| Trapassi, C | 1 |
| Tocco, F | 1 |
| Storci, G | 1 |
| Invidia, L | 1 |
| Vannini, I | 1 |
| Rossi, M | 1 |
| Marzi, E | 1 |
| Mishto, M | 1 |
| Capri, M | 1 |
| Olivieri, F | 1 |
| Antonicelli, R | 1 |
| Memo, M | 1 |
| Uberti, D | 1 |
| Nacmias, B | 1 |
| Sorbi, S | 1 |
| Monti, D | 1 |
| Franceschi, C | 1 |
| Horman, S | 1 |
| Vertommen, D | 1 |
| Heath, R | 1 |
| Neumann, D | 1 |
| Mouton, V | 1 |
| Woods, A | 1 |
| Schlattner, U | 1 |
| Wallimann, T | 1 |
| Carling, D | 1 |
| Hue, L | 1 |
| Rider, MH | 1 |
| Axelsen, LN | 1 |
| Stahlhut, M | 1 |
| Mohammed, S | 1 |
| Larsen, BD | 1 |
| Nielsen, MS | 1 |
| Holstein-Rathlou, NH | 1 |
| Andersen, S | 1 |
| Jensen, ON | 1 |
| Hennan, JK | 1 |
| Kjølbye, AL | 1 |
| Lampe, PD | 1 |
| Cooper, CD | 1 |
| King, TJ | 1 |
| Burt, JM | 1 |
| Chen, ZP | 1 |
| Mitchelhill, KI | 1 |
| Michell, BJ | 1 |
| Stapleton, D | 1 |
| Rodriguez-Crespo, I | 1 |
| Witters, LA | 1 |
| Power, DA | 1 |
| Ortiz de Montellano, PR | 1 |
| Kemp, BE | 1 |
| MacGowan, GA | 1 |
| Du, C | 1 |
| Cowan, DB | 1 |
| Stamm, C | 1 |
| McGowan, FX | 1 |
| Solaro, RJ | 1 |
| Koretsky, AP | 1 |
| Del Nido, PJ | 1 |
13 other studies available for serine and Myocardial Ischemia
| Article | Year |
|---|---|
Cardioprotective Mechanism of Leonurine against Myocardial Ischemia through a Liver-Cardiac Crosstalk Metabolomics Study.
Topics: Amino Acids; Animals; Coronary Artery Disease; Fatty Acids; Glycine; Liver; Metabolomics; Myocardial | 2022 |
Tumor necrosis factor-alpha upregulated PHLPP1 through activating nuclear factor-kappa B during myocardial ischemia/reperfusion.
Topics: Animals; Animals, Newborn; Disease Models, Animal; Gene Expression Regulation; Heart Ventricles; Mal | 2018 |
PPARα Stimulation Modulates Myocardial Ischemia-induced Activation of Renin-Angiotensin System.
Topics: Angiotensin-Converting Enzyme 2; Animals; Bradykinin; Clofibrate; Disease Models, Animal; Enzyme Act | 2015 |
Serum insulin-like growth factor binding protein-1 (IGFBP-1) phosphorylation status in subjects with and without ischaemic heart disease.
Topics: Adult; Cardiovascular Diseases; Enzyme-Linked Immunosorbent Assay; Female; Glucose Tolerance Test; H | 2010 |
Protective effect of ligustrazine against myocardial ischaemia reperfusion in rats: the role of endothelial nitric oxide synthase.
Topics: Animals; Apoptosis; Cardiotonic Agents; Caspase 3; Enzyme Inhibitors; Male; Myocardial Infarction; M | 2012 |
Role of RyR2 phosphorylation at S2814 during heart failure progression.
Topics: Adult; Animals; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cardiomegaly; Cardiomyopathy, Di | 2012 |
Chronic hypoxia increases endothelial nitric oxide synthase generation of nitric oxide by increasing heat shock protein 90 association and serine phosphorylation.
Topics: Animals; Animals, Newborn; Benzoquinones; Blotting, Western; Chronic Disease; Enzyme Activation; Enz | 2002 |
The different apoptotic potential of the p53 codon 72 alleles increases with age and modulates in vivo ischaemia-induced cell death.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Alleles; Apoptosis; Arginine; bcl-X Protein; Blotting, | 2004 |
Insulin antagonizes ischemia-induced Thr172 phosphorylation of AMP-activated protein kinase alpha-subunits in heart via hierarchical phosphorylation of Ser485/491.
Topics: Adenosine Monophosphate; AMP-Activated Protein Kinase Kinases; AMP-Activated Protein Kinases; Animal | 2006 |
Identification of ischemia-regulated phosphorylation sites in connexin43: A possible target for the antiarrhythmic peptide analogue rotigaptide (ZP123).
Topics: Amino Acid Sequence; Animals; Connexin 43; Heart Arrest; Male; Molecular Sequence Data; Myocardial I | 2006 |
Analysis of Connexin43 phosphorylated at S325, S328 and S330 in normoxic and ischemic heart.
Topics: Animals; Cell Communication; Cells, Cultured; Connexin 43; Fibroblasts; Gap Junctions; Heart Ventric | 2006 |
AMP-activated protein kinase phosphorylation of endothelial NO synthase.
Topics: Amino Acid Sequence; AMP-Activated Protein Kinases; Animals; Aorta; Calmodulin; Cattle; Endothelium, | 1999 |
Ischemic dysfunction in transgenic mice expressing troponin I lacking protein kinase C phosphorylation sites.
Topics: Alanine; Animals; Binding Sites; Calcium; Feedback; Female; Homeostasis; In Vitro Techniques; Mice; | 2001 |