serine has been researched along with Muscular Atrophy, Spinal in 5 studies
Serine: A non-essential amino acid occurring in natural form as the L-isomer. It is synthesized from GLYCINE or THREONINE. It is involved in the biosynthesis of PURINES; PYRIMIDINES; and other amino acids.
serine : An alpha-amino acid that is alanine substituted at position 3 by a hydroxy group.
Muscular Atrophy, Spinal: A group of disorders marked by progressive degeneration of motor neurons in the spinal cord resulting in weakness and muscular atrophy, usually without evidence of injury to the corticospinal tracts. Diseases in this category include Werdnig-Hoffmann disease and later onset SPINAL MUSCULAR ATROPHIES OF CHILDHOOD, most of which are hereditary. (Adams et al., Principles of Neurology, 6th ed, p1089)
| Excerpt | Relevance | Reference |
|---|---|---|
| " The response of the receptors to inhibitors of polyglutamine toxicity is altered by the amino acid exchanges suggesting that careful consideration is needed in the choice of potential therapies of disorders involving toxic polyQ species." | 1.35 | Specific N-terminal mutations in the human androgen receptor induce cytotoxicity. ( Cato, AC; Funderburk, SF; Mink, S; Shatkina, L; Weg-Remers, S; Weis, Q, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Palazzolo, I | 1 |
| Stack, C | 1 |
| Kong, L | 1 |
| Musaro, A | 1 |
| Adachi, H | 1 |
| Katsuno, M | 1 |
| Sobue, G | 1 |
| Taylor, JP | 1 |
| Sumner, CJ | 1 |
| Fischbeck, KH | 1 |
| Pennuto, M | 1 |
| LaFevre-Bernt, MA | 1 |
| Ellerby, LM | 1 |
| Marques, VD | 1 |
| Barreira, AA | 1 |
| Davis, MB | 1 |
| Abou-Sleiman, PM | 1 |
| Silva, WA | 1 |
| Zago, MA | 1 |
| Sobreira, C | 1 |
| Fazan, V | 1 |
| Marques, W | 1 |
| Cader, MZ | 1 |
| Ren, J | 1 |
| James, PA | 1 |
| Bird, LE | 1 |
| Talbot, K | 1 |
| Stammers, DK | 1 |
| Funderburk, SF | 1 |
| Shatkina, L | 1 |
| Mink, S | 1 |
| Weis, Q | 1 |
| Weg-Remers, S | 1 |
| Cato, AC | 1 |
5 other studies available for serine and Muscular Atrophy, Spinal
| Article | Year |
|---|---|
Overexpression of IGF-1 in muscle attenuates disease in a mouse model of spinal and bulbar muscular atrophy.
Topics: Animals; Behavior, Animal; Cell Line, Transformed; Chlorocebus aethiops; Class I Phosphatidylinosito | 2009 |
Kennedy's disease. Phosphorylation of the polyglutamine-expanded form of androgen receptor regulates its cleavage by caspase-3 and enhances cell death.
Topics: Alanine; Amino Acid Substitution; Base Sequence; Caspase 3; Caspases; Cell Death; Cell Line; DNA Pri | 2003 |
Expanding the phenotypes of the Pro56Ser VAPB mutation: proximal SMA with dysautonomia.
Topics: Adult; Autonomic Nervous System Diseases; Brazil; Electromyography; Female; Humans; Male; Middle Age | 2006 |
Crystal structure of human wildtype and S581L-mutant glycyl-tRNA synthetase, an enzyme underlying distal spinal muscular atrophy.
Topics: Amino Acid Substitution; Binding Sites; Crystallography, X-Ray; Dimerization; Distal Myopathies; Gly | 2007 |
Specific N-terminal mutations in the human androgen receptor induce cytotoxicity.
Topics: Amino Acid Sequence; Animals; Animals, Genetically Modified; Behavioral Symptoms; Butyrates; Chloroc | 2009 |