Page last updated: 2024-11-08

serine and Muscle Spasticity

serine has been researched along with Muscle Spasticity in 3 studies

Serine: A non-essential amino acid occurring in natural form as the L-isomer. It is synthesized from GLYCINE or THREONINE. It is involved in the biosynthesis of PURINES; PYRIMIDINES; and other amino acids.
serine : An alpha-amino acid that is alanine substituted at position 3 by a hydroxy group.

Muscle Spasticity: A form of muscle hypertonia associated with upper MOTOR NEURON DISEASE. Resistance to passive stretch of a spastic muscle results in minimal initial resistance (a free interval) followed by an incremental increase in muscle tone. Tone increases in proportion to the velocity of stretch. Spasticity is usually accompanied by HYPERREFLEXIA and variable degrees of MUSCLE WEAKNESS. (From Adams et al., Principles of Neurology, 6th ed, p54)

Research Excerpts

ExcerptRelevanceReference
"We report on two new cases of serine deficiency due respectively to 3-phosphoglycerate dehydrogenase (PHGDH) deficiency (Patient 1) and phosphoserine aminotransferase (PSAT1) deficiency (Patient 2), presenting with congenital microcephaly (<3rd centile at birth) and encephalopathy with spasticity."3.83Two new cases of serine deficiency disorders treated with l-serine. ( Bahi-Buisson, N; Boddaert, N; Brassier, A; de Lonlay, P; Desguerre, I; Habarou, F; Hubert, L; Kaminska, A; Ottolenghi, C; Valayannopoulos, V; Van Schaftingen, E; Wiame, E, 2016)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19901 (33.33)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (33.33)24.3611
2020's1 (33.33)2.80

Authors

AuthorsStudies
Tang, H1
Peng, T1
Yang, X1
Liu, L1
Xu, Y1
Zhao, Y1
Huang, S1
Fu, C1
Huang, Y1
Zhou, H1
Li, J1
He, L1
Wang, W1
Niu, H1
Xu, K1
Brassier, A1
Valayannopoulos, V1
Bahi-Buisson, N1
Wiame, E1
Hubert, L1
Boddaert, N1
Kaminska, A1
Habarou, F1
Desguerre, I1
Van Schaftingen, E1
Ottolenghi, C1
de Lonlay, P1
Ionasescu, V1
Stegink, L1
Mueller, S1
Weinstein, M1

Other Studies

3 other studies available for serine and Muscle Spasticity

ArticleYear
Plasma Metabolomic Changes in Children with Cerebral Palsy Exposed to Botulinum Neurotoxin.
    Journal of proteome research, 2022, 03-04, Volume: 21, Issue:3

    Topics: Botulinum Toxins, Type A; Cerebral Palsy; Child; Cysteine; Glycine; Humans; Injections, Intramuscula

2022
Two new cases of serine deficiency disorders treated with l-serine.
    European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society, 2016, Volume: 20, Issue:1

    Topics: Adult; Amino Acid Metabolism, Inborn Errors; Amino Acids; Carbohydrate Metabolism, Inborn Errors; Ch

2016
Amino acid abnormality in Sjögren-Larsson syndrome.
    Archives of neurology, 1973, Volume: 28, Issue:3

    Topics: Adolescent; Amino Acid Metabolism, Inborn Errors; Dental Enamel Hypoplasia; Epilepsy; Ethylamines; G

1973