Page last updated: 2024-11-08

serine and Muscle Contraction

serine has been researched along with Muscle Contraction in 71 studies

Serine: A non-essential amino acid occurring in natural form as the L-isomer. It is synthesized from GLYCINE or THREONINE. It is involved in the biosynthesis of PURINES; PYRIMIDINES; and other amino acids.
serine : An alpha-amino acid that is alanine substituted at position 3 by a hydroxy group.

Muscle Contraction: A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.

Research Excerpts

ExcerptRelevanceReference
"In the pulmonary artery isolated from 1-week hypoxia-induced pulmonary hypertensive rats, endothelial NO production stimulated by carbachol was decreased significantly in in situ visualization using diaminofluorescein-2 diacetate and also in cGMP content."3.71Decreased endothelial nitric-oxide synthase (eNOS) activity resulting from abnormal interaction between eNOS and its regulatory proteins in hypoxia-induced pulmonary hypertension. ( Hori, M; Karaki, H; Murata, T; Ozaki, H; Sato, K, 2002)
"We investigated the role of epithelium in smooth muscle contraction induced by leukotriene C4 (LTC4) in isolated human trachea."3.69Epithelial modulation of leukotriene-C4-induced human tracheal smooth muscle contraction. ( Hoshi, H; Sasaki, H; Sawai, T; Sekizawa, K; Yamauchi, K; Yamaya, M, 1995)
"Insulin sensitivity was measured by hyperinsulinemic euglycemic clamp (HEC) in mature female sheep (n = 7)."1.42Acute exercise increases insulin sensitivity in adult sheep: a new preclinical model. ( Falcão-Tebas, F; Gatford, KL; Hong, YH; Kaur, G; McConell, GK, 2015)
" L-Serine borate complex, 45 mM, used as an inhibitor of the degradation of LTC4 to LTD4 by the enzyme gamma-glutamyl transpeptidase, in paired airway segments (adjacent segments from the same branch), produced a small degree (about 3-fold) of shift to the right of the dose-response curve and reduction of the maximum response to LTC4."1.27Pharmacological evidence that human intralobar airways do not contain different receptors that mediate contractions to leukotriene C4 and leukotriene D4. ( Bernstein, PR; Buckner, CK; Coursin, DB; Krell, RD; Laravuso, RB; Will, JA, 1986)
"Cumulative dose-response curves to leukotriene C4 (LTC4) and leukotriene D4 (LTD)4 were obtained on indomethacin (5 microM) treated isolated guinea pig tracheal spiral strips."1.27Pharmacological comparison of L-serine borate and glutathione as inhibitors of metabolism of LTC4 to LTD4 by the isolated guinea pig trachea. ( Hand, JM; Schwalm, SF, 1987)
" With the exception of gamma-amino butyric acid and L-alanine benzyl ester all analogues which had appreciable activity gave dose-response curves parallel to L-alanine."1.25Isolation and identification of pharmacologically active amino acids in skin and their structure-activity relationship on the guinea-pig ileum. ( Lewis, GP; McMartin, C; Rosenthal, SR; Yates, C, 1972)

Research

Studies (71)

TimeframeStudies, this research(%)All Research%
pre-199022 (30.99)18.7374
1990's11 (15.49)18.2507
2000's17 (23.94)29.6817
2010's21 (29.58)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Jacko, D1
Bersiner, K1
Hebchen, J1
de Marées, M1
Bloch, W1
Gehlert, S1
Artamonov, M1
Momotani, K1
Utepbergenov, D1
Franke, A1
Khromov, A1
Derewenda, ZS1
Somlyo, AV1
Riquelme, MA1
Cea, LA1
Vega, JL1
Boric, MP1
Monyer, H1
Bennett, MV1
Frank, M1
Willecke, K1
Sáez, JC1
Hanft, LM1
Biesiadecki, BJ1
McDonald, KS1
Dougherty, PJ1
Nepiyushchikh, ZV1
Chakraborty, S1
Wang, W1
Davis, MJ1
Zawieja, DC1
Muthuchamy, M1
Huang, H1
Larsen, MR1
Palmisano, G1
Dai, J1
Lametsch, R1
Nalli, AD1
Kumar, DP1
Al-Shboul, O1
Mahavadi, S1
Kuemmerle, JF1
Grider, JR1
Murthy, KS1
McConell, GK1
Kaur, G1
Falcão-Tebas, F1
Hong, YH1
Gatford, KL1
Chen, L1
Chen, Q1
Xie, B1
Quan, C1
Sheng, Y1
Zhu, S1
Rong, P1
Zhou, S1
Sakamoto, K4
MacKintosh, C1
Wang, HY1
Chen, S1
Li, J1
Wang, R1
Tang, DD1
d'Emmanuele di Villa Bianca, R1
Mitidieri, E1
Fusco, F1
Russo, A1
Pagliara, V1
Tramontano, T1
Donnarumma, E1
Mirone, V1
Cirino, G1
Russo, G1
Sorrentino, R1
Treebak, JT1
Taylor, EB1
Witczak, CA1
An, D1
Toyoda, T1
Koh, HJ1
Xie, J1
Feener, EP1
Wojtaszewski, JF3
Hirshman, MF5
Goodyear, LJ5
Kolnes, AJ1
Ingvaldsen, A1
Bolling, A1
Stuenaes, JT1
Kreft, M1
Zorec, R1
Shepherd, PR1
Jensen, J2
Lai, YC1
Zarrinpashneh, E1
Belke, DD1
Kiilerich, K1
Ringholm, S1
Biensø, RS1
Fisher, JP1
Iversen, N1
van Hall, G1
Saltin, B1
Lundby, C1
Calbet, JA1
Pilegaard, H1
Mamidi, R1
Gollapudi, SK1
Mallampalli, SL1
Chandra, M1
Schweitzer, GG1
Arias, EB1
Cartee, GD1
Ghasemi-Kasman, M1
Dehpour, AR1
Mani, AR1
Andersson, DC1
Betzenhauser, MJ1
Reiken, S1
Umanskaya, A1
Shiomi, T1
Marks, AR1
Lang, SE1
Robinson, DA1
Wu, HC1
Herron, TJ1
Wahr, PA1
Westfall, MV1
Murata, T1
Sato, K1
Hori, M2
Ozaki, H2
Karaki, H2
Nolte, LA1
Han, DH1
Hansen, PA1
Hucker, KA1
Holloszy, JO1
Yasuda, K1
Kim, YS1
Egawa, M1
Kanzaki, H1
Nakazawa, H1
Seto, M2
Somara, S1
Bitar, KN1
Fujii, N2
Boppart, MD1
Dufresne, SD2
Crowley, PF1
Jozsi, AC1
Yu, H1
Aschenbach, WG2
Kim, S1
Miyazaki, H1
Rui, L1
White, MF1
Donsmark, M1
Langfort, J1
Holm, C1
Ploug, T1
Galbo, H1
Pfitzer, G1
Wirth, A1
Lucius, C1
Brkic-Koric, D1
Manser, E1
de Lanerolle, P1
Arner, A1
Wooldridge, AA1
MacDonald, JA1
Erdodi, F1
Ma, C1
Borman, MA1
Hartshorne, DJ1
Haystead, TA1
Khapchaev, AY1
Krymsky, MA1
Sidorova, MV1
Bespalova, ZhD1
Wang, CL1
Shirinsky, VP1
Vorotnikov, AV1
Meeks, MK1
Ripley, ML1
Jin, Z1
Rembold, CM1
Iyer, D1
Chang, D1
Marx, J1
Wei, L1
Olson, EN1
Parmacek, MS1
Balasubramanyam, A1
Schwartz, RJ1
Arnolds, DE1
Kramer, HF1
Yayama, K1
Hiyoshi, H1
Imazu, D1
Okamoto, H1
Barton, B1
Ayer, G1
Maughan, DW1
Vigoreaux, JO1
Snyder, DW4
Krell, RD5
Aharony, D2
Dobson, P1
Tsai, BS1
Krilis, S1
Lewis, RA1
Corey, EJ1
Austen, KF1
Currie, MG1
Geller, DM1
Cole, BR1
Siegel, NR1
Fok, KF1
Adams, SP1
Eubanks, SR1
Galluppi, GR1
Needleman, P1
Yamaya, M1
Sekizawa, K1
Yamauchi, K1
Hoshi, H1
Sawai, T1
Sasaki, H1
Sweeney, HL1
Yang, Z1
Zhi, G1
Stull, JT1
Trybus, KM1
Zhang, R1
Zhao, J2
Potter, JD2
Uyama, Y1
Imaizumi, Y1
Watanabe, M1
Walsh, MP3
Parsons, B1
Szczesna, D1
Van Slooten, G1
Kerrick, WG1
Putkey, JA1
Mita, M1
Nagumo, H1
Sakurada, K1
Sasaki, Y1
Beall, A1
Bagwell, D1
Woodrum, D1
Stoming, TA1
Kato, K1
Suzuki, A1
Rasmussen, H1
Brophy, CM1
Higaki, Y1
Michael, MD1
Kahn, CR1
Bäck, M1
Kumlin, M1
Cotgreave, IA1
Dahlén, SE1
Haydon, CE1
Watt, PW1
Morrice, N1
Knebel, A1
Gaestel, M1
Cohen, P1
Fujiwara, H1
Inagaki, C1
Ikeda, Y1
Tanaka, C1
Fareed, J1
Kindel, G1
Messmore, HL1
Balis, JU1
Murakami, H1
Ishikawa, T1
Sato, T1
Sorrels, TL1
Bostock, E1
Fedyna, JS1
Redkar-Brown, D1
Charette, L1
Jones, TR1
Bdolah, A1
Wollberg, Z1
Fleminger, G1
Kochva, E1
Muccitelli, RM3
Tucker, SS4
Hay, DW3
Torphy, TJ3
Wasserman, MA3
Vickery-Clark, LM1
Wilson, KA2
Gleason, JG1
Hall, RF1
Buckner, CK1
Laravuso, RB1
Coursin, DB1
Bernstein, PR1
Will, JA1
Weichman, BM2
Hand, JM1
Schwalm, SF1
Lewis, GP1
McMartin, C1
Rosenthal, SR1
Yates, C1
Yamazaki, K1
Moriya, H1
Polácek, I1
Krejcí, I1
Nesvadba, H1
Rudinger, J1
Cuparencu, B1
Bârsan, ET1
Bârzu, T1
Klein, B1
Budzko, DB1
Bokisch, VA1
Müller-Eberhard, HJ1

Other Studies

71 other studies available for serine and Muscle Contraction

ArticleYear
Phosphorylation of αB-crystallin and its cytoskeleton association differs in skeletal myofiber types depending on resistance exercise intensity and volume.
    Journal of applied physiology (Bethesda, Md. : 1985), 2019, 06-01, Volume: 126, Issue:6

    Topics: Adult; alpha-Crystallin B Chain; Cytoskeleton; Exercise; Humans; Male; Muscle Contraction; Muscle Fi

2019
The p90 ribosomal S6 kinase (RSK) is a mediator of smooth muscle contractility.
    PloS one, 2013, Volume: 8, Issue:3

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Calcium; Dose-Response

2013
The ATP required for potentiation of skeletal muscle contraction is released via pannexin hemichannels.
    Neuropharmacology, 2013, Volume: 75

    Topics: 4-Chloro-7-nitrobenzofurazan; Action Potentials; Adenosine Diphosphate; Adenosine Triphosphate; Anim

2013
Length dependence of striated muscle force generation is controlled by phosphorylation of cTnI at serines 23/24.
    The Journal of physiology, 2013, Sep-15, Volume: 591, Issue:18

    Topics: Animals; Cyclic AMP-Dependent Protein Kinases; Male; Muscle Contraction; Muscle Fibers, Slow-Twitch;

2013
PKC activation increases Ca²⁺ sensitivity of permeabilized lymphatic muscle via myosin light chain 20 phosphorylation-dependent and -independent mechanisms.
    American journal of physiology. Heart and circulatory physiology, 2014, Mar-01, Volume: 306, Issue:5

    Topics: Animals; Bacterial Toxins; Calcium Signaling; Calmodulin-Binding Proteins; Cell Membrane Permeabilit

2014
Quantitative phosphoproteomic analysis of porcine muscle within 24 h postmortem.
    Journal of proteomics, 2014, Jun-25, Volume: 106

    Topics: Amino Acid Motifs; Animals; Apoptosis; Chromatography, Liquid; Computational Biology; Databases, Pro

2014
Regulation of Gβγi-dependent PLC-β3 activity in smooth muscle: inhibitory phosphorylation of PLC-β3 by PKA and PKG and stimulatory phosphorylation of Gαi-GTPase-activating protein RGS2 by PKG.
    Cell biochemistry and biophysics, 2014, Volume: 70, Issue:2

    Topics: Adenosine; Animals; Calcium; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP-Dependent Protein Kina

2014
Acute exercise increases insulin sensitivity in adult sheep: a new preclinical model.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2015, Mar-15, Volume: 308, Issue:6

    Topics: Age Factors; Animals; Biopsy; Blood Glucose; Female; Glucose Clamp Technique; Insulin; Insulin Resis

2015
Disruption of the AMPK-TBC1D1 nexus increases lipogenic gene expression and causes obesity in mice via promoting IGF1 secretion.
    Proceedings of the National Academy of Sciences of the United States of America, 2016, 06-28, Volume: 113, Issue:26

    Topics: Adipocytes; Adipose Tissue; AMP-Activated Protein Kinases; Animals; Cells, Cultured; Chondrocytes; G

2016
Vimentin dephosphorylation at ser-56 is regulated by type 1 protein phosphatase in smooth muscle.
    Respiratory research, 2016, 07-25, Volume: 17, Issue:1

    Topics: Actins; Animals; Crk-Associated Substrate Protein; Dose-Response Relationship, Drug; Female; Male; M

2016
Urothelium muscarinic activation phosphorylates CBS(Ser227) via cGMP/PKG pathway causing human bladder relaxation through H2S production.
    Scientific reports, 2016, 08-11, Volume: 6

    Topics: Carbachol; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Cystathionine beta-Synthase; Humans; Hy

2016
Identification of a novel phosphorylation site on TBC1D4 regulated by AMP-activated protein kinase in skeletal muscle.
    American journal of physiology. Cell physiology, 2010, Volume: 298, Issue:2

    Topics: Adult; Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Androstadienes; Animals; Electric

2010
Caffeine and theophylline block insulin-stimulated glucose uptake and PKB phosphorylation in rat skeletal muscles.
    Acta physiologica (Oxford, England), 2010, Volume: 200, Issue:1

    Topics: Animals; Caffeine; Dantrolene; Dose-Response Relationship, Drug; Electric Stimulation; Glucose; Gluc

2010
Additive effect of contraction and insulin on glucose uptake and glycogen synthase in muscle with different glycogen contents.
    Journal of applied physiology (Bethesda, Md. : 1985), 2010, Volume: 108, Issue:5

    Topics: AMP-Activated Protein Kinases; Animals; Food Deprivation; Glucose; Glucose Transporter Type 4; Glyco

2010
Swim-exercised mice show a decreased level of protein O-GlcNAcylation and expression of O-GlcNAc transferase in heart.
    Journal of applied physiology (Bethesda, Md. : 1985), 2011, Volume: 111, Issue:1

    Topics: Acetylglucosamine; Adaptation, Physiological; Animals; Cardiomegaly; Down-Regulation; Gene Expressio

2011
Exercise-induced pyruvate dehydrogenase activation is not affected by 7 days of bed rest.
    Journal of applied physiology (Bethesda, Md. : 1985), 2011, Volume: 111, Issue:3

    Topics: Adult; Bed Rest; Biopsy; Blood Glucose; Enzyme Activation; Exercise; Exercise Test; Gene Expression

2011
Alanine or aspartic acid substitutions at serine23/24 of cardiac troponin I decrease thin filament activation, with no effect on crossbridge detachment kinetics.
    Archives of biochemistry and biophysics, 2012, Sep-01, Volume: 525, Issue:1

    Topics: Adenosine Triphosphatases; Alanine; Amino Acid Substitution; Animals; Aspartic Acid; Calcium; Cyclic

2012
Sustained postexercise increases in AS160 Thr642 and Ser588 phosphorylation in skeletal muscle without sustained increases in kinase phosphorylation.
    Journal of applied physiology (Bethesda, Md. : 1985), 2012, Dec-15, Volume: 113, Issue:12

    Topics: Animals; Binding Sites; GTPase-Activating Proteins; Male; Muscle Contraction; Phosphorylation; Phosp

2012
D-serine modulates non-adrenergic non-cholinergic contraction of lower esophageal sphincter in rats.
    European journal of pharmacology, 2012, Dec-05, Volume: 696, Issue:1-3

    Topics: Actins; Animals; D-Amino-Acid Oxidase; Esophageal Sphincter, Lower; In Vitro Techniques; Liver; Male

2012
Stress-induced increase in skeletal muscle force requires protein kinase A phosphorylation of the ryanodine receptor.
    The Journal of physiology, 2012, Dec-15, Volume: 590, Issue:24

    Topics: Adrenergic beta-Agonists; Animals; Calcium Signaling; Cyclic AMP-Dependent Protein Kinases; Isoprote

2012
Myofilament incorporation and contractile function after gene transfer of cardiac troponin I Ser43/45Ala.
    Archives of biochemistry and biophysics, 2013, Jul-01, Volume: 535, Issue:1

    Topics: Adenoviridae; Alanine; Amino Acid Substitution; Animals; Blotting, Western; Calcium; Culture Media,

2013
Decreased endothelial nitric-oxide synthase (eNOS) activity resulting from abnormal interaction between eNOS and its regulatory proteins in hypoxia-induced pulmonary hypertension.
    The Journal of biological chemistry, 2002, Nov-15, Volume: 277, Issue:46

    Topics: Animals; Blotting, Western; Body Weight; Calcium; Carbachol; Cell Membrane; Cyclic GMP; Electrophore

2002
A peroxovanadium compound stimulates muscle glucose transport as powerfully as insulin and contractions combined.
    Diabetes, 2003, Volume: 52, Issue:8

    Topics: Androstadienes; Animals; Chromones; Enzyme Inhibitors; Glucose; Hypoglycemic Agents; Insulin; Insuli

2003
Possible role of the protein kinase C/CPI-17 pathway in the augmented contraction of human myometrium after gestation.
    British journal of pharmacology, 2003, Volume: 140, Issue:7

    Topics: Adult; Blotting, Western; Calcium; Carbazoles; Enzyme Activators; Enzyme Inhibitors; Female; Humans;

2003
Tropomyosin interacts with phosphorylated HSP27 in agonist-induced contraction of smooth muscle.
    American journal of physiology. Cell physiology, 2004, Volume: 286, Issue:6

    Topics: Acetylcholine; Amino Acid Sequence; Animals; Cells, Cultured; Glutathione Transferase; Heat-Shock Pr

2004
Overexpression or ablation of JNK in skeletal muscle has no effect on glycogen synthase activity.
    American journal of physiology. Cell physiology, 2004, Volume: 287, Issue:1

    Topics: Animals; Down-Regulation; Electroporation; Enzyme Activation; Gene Transfer Techniques; Glycogen Syn

2004
Contractions induce phosphorylation of the AMPK site Ser565 in hormone-sensitive lipase in muscle.
    Biochemical and biophysical research communications, 2004, Apr-09, Volume: 316, Issue:3

    Topics: AMP-Activated Protein Kinases; Animals; Binding Sites; Blotting, Western; Cyclic AMP-Dependent Prote

2004
Regulation of smooth muscle contraction by calcium, monomeric GTPases of the Rho subfamily and their effector kinases.
    Advances in experimental medicine and biology, 2003, Volume: 538

    Topics: Animals; Calcium; Carbachol; Chelating Agents; Diazonium Compounds; Female; Guinea Pigs; Light; Male

2003
Smooth muscle phosphatase is regulated in vivo by exclusion of phosphorylation of threonine 696 of MYPT1 by phosphorylation of Serine 695 in response to cyclic nucleotides.
    The Journal of biological chemistry, 2004, Aug-13, Volume: 279, Issue:33

    Topics: Animals; Apoptosis Regulatory Proteins; Binding Sites; Blotting, Western; Calcium; Calcium-Calmoduli

2004
Novel phosphospecific antibodies for monitoring phosphorylation of proteins encoded by the myosin light chain kinase genetic locus.
    Biochemistry. Biokhimiia, 2004, Volume: 69, Issue:7

    Topics: Amino Acid Sequence; Animals; Calcium; Colforsin; Cyclic AMP-Dependent Protein Kinases; Male; Mitoge

2004
Heat shock protein 20-mediated force suppression in forskolin-relaxed swine carotid artery.
    American journal of physiology. Cell physiology, 2005, Volume: 288, Issue:3

    Topics: Actins; Amino Acid Sequence; Animals; Carotid Arteries; Colforsin; Heat-Shock Proteins; HSP20 Heat-S

2005
Serum response factor MADS box serine-162 phosphorylation switches proliferation and myogenic gene programs.
    Proceedings of the National Academy of Sciences of the United States of America, 2006, Mar-21, Volume: 103, Issue:12

    Topics: Actins; Amino Acid Sequence; Amino Acid Substitution; Animals; Aspartic Acid; Cell Differentiation;

2006
Role of Akt2 in contraction-stimulated cell signaling and glucose uptake in skeletal muscle.
    American journal of physiology. Endocrinology and metabolism, 2006, Volume: 291, Issue:5

    Topics: Animals; Blood Glucose; Glycogen; Glycogen Synthase Kinase 3; Mice; Mice, Inbred C57BL; Mice, Mutant

2006
Angiotensin II stimulates endothelial NO synthase phosphorylation in thoracic aorta of mice with abdominal aortic banding via type 2 receptor.
    Hypertension (Dallas, Tex. : 1979), 2006, Volume: 48, Issue:5

    Topics: Angiotensin II; Animals; Aorta, Abdominal; Aorta, Thoracic; Cyclic AMP-Dependent Protein Kinases; En

2006
Site directed mutagenesis of Drosophila flightin disrupts phosphorylation and impairs flight muscle structure and mechanics.
    Journal of muscle research and cell motility, 2007, Volume: 28, Issue:4-5

    Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Animals, Genetically Modified; Binding Sites;

2007
Pharmacological evidence for a distinct leukotriene C4 receptor in guinea-pig trachea.
    The Journal of pharmacology and experimental therapeutics, 1984, Volume: 231, Issue:3

    Topics: Animals; Chromones; Cysteine; Guinea Pigs; In Vitro Techniques; Leukotriene E4; Male; Muscle Contrac

1984
Pharmacological and biochemical evidence for metabolism of peptide leukotrienes by guinea-pig airway smooth muscle in vitro.
    The Journal of pharmacology and experimental therapeutics, 1984, Volume: 231, Issue:2

    Topics: Aminopeptidases; Animals; Carbachol; Cysteine; Dose-Response Relationship, Drug; gamma-Glutamyltrans

1984
Bioconversion of C-6 sulfidopeptide leukotrienes by the responding guinea pig ileum determines the time course of its contraction.
    The Journal of clinical investigation, 1983, Volume: 71, Issue:4

    Topics: Animals; Cysteine; Depression, Chemical; Guinea Pigs; Ileum; Intestinal Mucosa; Leukotriene E4; Musc

1983
Purification and sequence analysis of bioactive atrial peptides (atriopeptins).
    Science (New York, N.Y.), 1984, Jan-06, Volume: 223, Issue:4631

    Topics: Amino Acid Sequence; Animals; Arginine; Chromatography, High Pressure Liquid; Chromatography, Ion Ex

1984
Epithelial modulation of leukotriene-C4-induced human tracheal smooth muscle contraction.
    American journal of respiratory and critical care medicine, 1995, Volume: 151, Issue:3 Pt 1

    Topics: Aged; Borates; Epithelium; gamma-Glutamyltransferase; Humans; In Vitro Techniques; Leukotriene C4; M

1995
Charge replacement near the phosphorylatable serine of the myosin regulatory light chain mimics aspects of phosphorylation.
    Proceedings of the National Academy of Sciences of the United States of America, 1994, Feb-15, Volume: 91, Issue:4

    Topics: Amino Acid Sequence; Animals; Gizzard, Avian; Humans; Models, Biological; Molecular Sequence Data; M

1994
Phosphorylation of both serine residues in cardiac troponin I is required to decrease the Ca2+ affinity of cardiac troponin C.
    The Journal of biological chemistry, 1995, Dec-22, Volume: 270, Issue:51

    Topics: Amino Acid Sequence; Animals; Base Sequence; Calcium; Cattle; Cyclic AMP-Dependent Protein Kinases;

1995
Inhibition by calponin of isometric force in demembranated vascular smooth muscle strips: the critical role of serine-175.
    The Biochemical journal, 1996, Oct-15, Volume: 319 ( Pt 2)

    Topics: Animals; Calcium-Binding Proteins; Calponins; Microfilament Proteins; Muscle Contraction; Muscle, Sm

1996
The effect of pH on the Ca2+ affinity of the Ca2+ regulatory sites of skeletal and cardiac troponin C in skinned muscle fibres.
    Journal of muscle research and cell motility, 1997, Volume: 18, Issue:5

    Topics: Amino Acid Substitution; Animals; Binding Sites; Calcium; Cysteine; Fluorescent Dyes; Heart; Hydroge

1997
alpha1-Adrenoceptor-mediated phosphorylation of myosin in rat-tail arterial smooth muscle.
    The Biochemical journal, 1997, Nov-01, Volume: 327 ( Pt 3)

    Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; An

1997
HA1077, a protein kinase inhibitor, inhibits calponin phosphorylation on Ser175 in porcine coronary artery.
    European journal of pharmacology, 1998, Nov-06, Volume: 360, Issue:2-3

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Arteries; Calcium-Binding Proteins; Calponin

1998
The small heat shock-related protein, HSP20, is phosphorylated on serine 16 during cyclic nucleotide-dependent relaxation.
    The Journal of biological chemistry, 1999, Apr-16, Volume: 274, Issue:16

    Topics: Amino Acid Sequence; Animals; Base Sequence; Cattle; Cyclic AMP; Cyclic AMP-Dependent Protein Kinase

1999
Exercise modulates postreceptor insulin signaling and glucose transport in muscle-specific insulin receptor knockout mice.
    The Journal of clinical investigation, 1999, Volume: 104, Issue:9

    Topics: Animals; Biological Transport; Deoxyglucose; Glucose; Glucose Tolerance Test; Glycogen; Glycogen Syn

1999
An alternative pathway for metabolism of leukotriene D(4): effects on contractions to cysteinyl-leukotrienes in the guinea-pig trachea.
    British journal of pharmacology, 2001, Volume: 133, Issue:7

    Topics: Animals; Borates; Cysteine; Dicarboxylic Acids; Dose-Response Relationship, Drug; Glutathione; Guine

2001
Identification of a phosphorylation site on skeletal muscle myosin light chain kinase that becomes phosphorylated during muscle contraction.
    Archives of biochemistry and biophysics, 2002, Jan-15, Volume: 397, Issue:2

    Topics: 14-3-3 Proteins; Actins; Amino Acid Sequence; Animals; Calcium-Calmodulin-Dependent Protein Kinases;

2002
Contraction regulation of Akt in rat skeletal muscle.
    The Journal of biological chemistry, 2002, Apr-05, Volume: 277, Issue:14

    Topics: Androstadienes; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Chromones; Electrophoresis, P

2002
[Synthesis of norepinephrine from 3,4-dihydroxyphenylserine by L-aromatic amino acid decarboxylase of the rat brain and kidneys].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1976, Volume: 72, Issue:7

    Topics: Animals; Aorta; Brain; Decarboxylation; Dopa Decarboxylase; Droxidopa; Female; Hydrogen-Ion Concentr

1976
Antagonism of the bradykinin induced contractile response of isolated smooth muscle preparations by low molecular weight synthetic chromogenic peptide substrates for serine proteases.
    Advances in the biosciences, 1978, Jul-22, Volume: 17

    Topics: Animals; Bradykinin; Female; Guinea Pigs; Ileum; Muscle Contraction; Muscle, Smooth; Oligopeptides;

1978
Influences of serine protease inhibitors on the relaxation in acetylcholine-contracture of anterior byssal retractor of Mytilus edulis.
    The Journal of Nihon University School of Dentistry, 1976, Volume: 18, Issue:4

    Topics: Acetylcholine; Animals; Bivalvia; In Vitro Techniques; Muscle Contraction; Muscle Relaxation; Protea

1976
Induction of feeding by 7-chlorokynurenic acid, a strychnine-insensitive glycine binding site antagonist.
    Brain research, 1992, Feb-14, Volume: 572, Issue:1-2

    Topics: Analysis of Variance; Animals; Ataxia; Dose-Response Relationship, Drug; Feeding Behavior; Glycine;

1992
Pharmacologic characterization of the contractile activity of peptide leukotrienes in guinea-pig pulmonary artery.
    Prostaglandins, 1990, Volume: 39, Issue:5

    Topics: Acetophenones; Animals; Borates; Drug Synergism; Endothelium, Vascular; Guinea Pigs; In Vitro Techni

1990
Effects of L-serine borate on antagonism of leukotriene C4-induced contractions of guinea-pig trachea.
    British journal of pharmacology, 1987, Volume: 91, Issue:1

    Topics: 1-Methyl-3-isobutylxanthine; Albuterol; Animals; Borates; Bucladesine; Guinea Pigs; In Vitro Techniq

1987
SRTX-d, a new native peptide of the endothelin/sarafotoxin family.
    FEBS letters, 1989, Oct-09, Volume: 256, Issue:1-2

    Topics: Amino Acid Sequence; Animals; Aorta; Binding Sites; Chromatography, DEAE-Cellulose; Endothelins; End

1989
Is the guinea pig trachea a good in vitro model of human large and central airways? Comparison on leukotriene-, methacholine-, histamine- and antigen-induced contractions.
    The Journal of pharmacology and experimental therapeutics, 1987, Volume: 243, Issue:2

    Topics: Adult; Animals; Antigens; Borates; Bronchi; Child; Chromones; Dicarboxylic Acids; Female; Guinea Pig

1987
Pharmacologic profile of SK&F 104353: a novel, potent and selective peptidoleukotriene receptor antagonist in guinea pig and human airways.
    The Journal of pharmacology and experimental therapeutics, 1987, Volume: 243, Issue:2

    Topics: 2',3'-Cyclic-Nucleotide Phosphodiesterases; Adult; Animals; Borates; Bronchi; Child; Dicarboxylic Ac

1987
Pharmacological evidence that human intralobar airways do not contain different receptors that mediate contractions to leukotriene C4 and leukotriene D4.
    The Journal of pharmacology and experimental therapeutics, 1986, Volume: 237, Issue:2

    Topics: Arachidonic Acid; Arachidonic Acids; Borates; Chromones; Cysteine; Dose-Response Relationship, Drug;

1986
Differential rank order of potency for antagonism of LTC4- and LTD4-induced contractions of guinea pig trachea.
    Prostaglandins, leukotrienes, and medicine, 1986, Volume: 23, Issue:1

    Topics: Animals; Borates; Chromones; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Receptors,

1986
Pharmacology of peptide leukotrienes on ferret isolated airway smooth muscle.
    Prostaglandins, 1986, Volume: 32, Issue:2

    Topics: Animals; Borates; Carbachol; Chromones; Ferrets; In Vitro Techniques; Leukotriene E4; Muscle Contrac

1986
Differences in the ability of salbutamol to prevent and reverse LTC4-induced contractions of the guinea-pig isolated trachea: influence of l-serine borate.
    European journal of pharmacology, 1986, Jul-31, Volume: 126, Issue:3

    Topics: Albuterol; Animals; Borates; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smo

1986
Pharmacological comparison of L-serine borate and glutathione as inhibitors of metabolism of LTC4 to LTD4 by the isolated guinea pig trachea.
    Prostaglandins, 1987, Volume: 33, Issue:5

    Topics: Animals; Borates; Glutathione; Guinea Pigs; In Vitro Techniques; Indomethacin; Male; Muscle Contract

1987
Differentiation of the mechanisms by which leukotrienes C4 and D4 elicit contraction of the guinea pig trachea.
    Prostaglandins, 1985, Volume: 29, Issue:4

    Topics: Airway Resistance; Animals; Borates; Chromones; Guinea Pigs; In Vitro Techniques; Male; Muscle Contr

1985
Isolation and identification of pharmacologically active amino acids in skin and their structure-activity relationship on the guinea-pig ileum.
    British journal of pharmacology, 1972, Volume: 45, Issue:1

    Topics: Alanine; Amino Acids; Aminobutyrates; Animals; Atropine; Chromatography, Ion Exchange; Esters; Guine

1972
Properties of colostrokinin from bovine colostrum.
    Biochemical pharmacology, 1969, Volume: 18, Issue:10

    Topics: Acetone; Amino Acids; Animals; Blood; Bradykinin; Capillary Permeability; Cattle; Chromatography, Ge

1969
Action of (1,6-di-alanine)-oxytocin and (1,6-di-serine)-oxytocin on the rat uterus and mammary gland in vitro.
    European journal of pharmacology, 1970, Volume: 9, Issue:2

    Topics: Alanine; Animals; Calcium; Female; In Vitro Techniques; Magnesium; Mammary Glands, Animal; Muscle Co

1970
[Separation of some phosphatides from striated muscle with action on smooth muscle].
    Fiziologia normala si patologica, 1970, Volume: 16, Issue:6

    Topics: Animals; Choline; Ethylamines; Female; Muscle Contraction; Muscle, Smooth; Muscles; Phospholipids; P

1970
A fragment of the third component of human complement with anaphylatoxin activity.
    Biochemistry, 1971, Mar-30, Volume: 10, Issue:7

    Topics: Amino Acids; Animals; Arginine; Autoanalysis; Carboxypeptidases; Chromatography, Gel; Complement Sys

1971