serine has been researched along with Multiple System Atrophy Syndrome in 4 studies
Serine: A non-essential amino acid occurring in natural form as the L-isomer. It is synthesized from GLYCINE or THREONINE. It is involved in the biosynthesis of PURINES; PYRIMIDINES; and other amino acids.
serine : An alpha-amino acid that is alanine substituted at position 3 by a hydroxy group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Parkinson's disease (PD) and multiple system atrophy (MSA) are characterized pathologically by inclusions in the brain containing alpha-synuclein, which is phosphorylated at serine 129." | 7.73 | alpha-synuclein from platelets is not phosphorylated at serine 129 in Parkinson's disease and multiple system atrophy. ( Barrett, JM; Fontaine, D; Shults, CW, 2006) |
| "Increasing evidence suggests that phosphorylation may play an important role in the oligomerization, fibrillogenesis, Lewy body (LB) formation, and neurotoxicity of alpha-synuclein (alpha-syn) in Parkinson disease." | 3.76 | Phosphorylation at S87 is enhanced in synucleinopathies, inhibits alpha-synuclein oligomerization, and influences synuclein-membrane interactions. ( Aebischer, P; Chegini, F; Chiappe, D; Eliezer, D; Fernandez, CO; Gai, WP; Kim, HY; Lamberto, GR; Lashuel, HA; Masliah, E; Moniatte, M; Oueslati, A; Paleologou, KE; Rospigliosi, CC; Schmid, A; Schneider, BL; Shakked, G; Zweckstetter, M, 2010) |
| "Parkinson's disease (PD) and multiple system atrophy (MSA) are characterized pathologically by inclusions in the brain containing alpha-synuclein, which is phosphorylated at serine 129." | 3.73 | alpha-synuclein from platelets is not phosphorylated at serine 129 in Parkinson's disease and multiple system atrophy. ( Barrett, JM; Fontaine, D; Shults, CW, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Nagao, M | 1 |
| Hayashi, H | 1 |
| Paleologou, KE | 1 |
| Oueslati, A | 1 |
| Shakked, G | 1 |
| Rospigliosi, CC | 1 |
| Kim, HY | 1 |
| Lamberto, GR | 1 |
| Fernandez, CO | 1 |
| Schmid, A | 1 |
| Chegini, F | 1 |
| Gai, WP | 1 |
| Chiappe, D | 1 |
| Moniatte, M | 1 |
| Schneider, BL | 1 |
| Aebischer, P | 1 |
| Eliezer, D | 1 |
| Zweckstetter, M | 1 |
| Masliah, E | 1 |
| Lashuel, HA | 1 |
| Hasegawa, T | 1 |
| Baba, T | 1 |
| Kobayashi, M | 1 |
| Konno, M | 1 |
| Sugeno, N | 1 |
| Kikuchi, A | 1 |
| Itoyama, Y | 1 |
| Takeda, A | 1 |
| Shults, CW | 1 |
| Barrett, JM | 1 |
| Fontaine, D | 1 |
4 other studies available for serine and Multiple System Atrophy Syndrome
| Article | Year |
|---|---|
Glycogen synthase kinase-3beta is associated with Parkinson's disease.
Topics: Aged; Amino Acid Sequence; Biomarkers; Brain; Cytosol; Female; Glycogen Synthase Kinase 3; Glycogen | 2009 |
Phosphorylation at S87 is enhanced in synucleinopathies, inhibits alpha-synuclein oligomerization, and influences synuclein-membrane interactions.
Topics: alpha-Synuclein; Alzheimer Disease; Amino Acid Sequence; Animals; Brain; Cell Membrane; Creatine Kin | 2010 |
Role of TPPP/p25 on α-synuclein-mediated oligodendroglial degeneration and the protective effect of SIRT2 inhibition in a cellular model of multiple system atrophy.
Topics: alpha-Synuclein; Apoptosis; Gene Expression Regulation, Enzymologic; Glycogen Synthase Kinase 3; HEK | 2010 |
alpha-synuclein from platelets is not phosphorylated at serine 129 in Parkinson's disease and multiple system atrophy.
Topics: Adult; Aged; alpha-Synuclein; Animals; Arabidopsis Proteins; Blood Platelets; Blotting, Western; Car | 2006 |