serine has been researched along with Long QT Syndrome in 9 studies
Serine: A non-essential amino acid occurring in natural form as the L-isomer. It is synthesized from GLYCINE or THREONINE. It is involved in the biosynthesis of PURINES; PYRIMIDINES; and other amino acids.
serine : An alpha-amino acid that is alanine substituted at position 3 by a hydroxy group.
Long QT Syndrome: A condition that is characterized by episodes of fainting (SYNCOPE) and varying degree of ventricular arrhythmia as indicated by the prolonged QT interval. The inherited forms are caused by mutation of genes encoding cardiac ion channel proteins. The two major forms are ROMANO-WARD SYNDROME and JERVELL-LANGE NIELSEN SYNDROME.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Congenital long QT syndrome is characterized by a prolongation of ventricular repolarization and recurrent episodes of life-threatening ventricular tachyarrhythmias, often leading to sudden death." | 1.35 | Congenital long QT syndrome caused by the F275S KCNQ1 mutation: mechanism of impaired channel function. ( Chen, XL; Du, R; Guan, SM; Kang, CL; Ke, QM; Li, W; Song, ZF; Tian, L; Wang, B; Wang, QF; Xu, QM; Yang, JG; Zhang, SY, 2009) |
| "Congenital long QT syndrome is a cardiac disorder characterized by prolongation of QT interval on the surface ECG associated with syncopal attacks and a high risk of sudden death." | 1.35 | The G314S KCNQ1 mutation exerts a dominant-negative effect on expression of KCNQ1 channels in oocytes. ( Du, R; Li, W; Song, ZF; Tian, L; Wang, QF; Yang, JG, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (22.22) | 18.2507 |
| 2000's | 6 (66.67) | 29.6817 |
| 2010's | 1 (11.11) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yamaguchi, Y | 1 |
| Nishide, K | 1 |
| Kato, M | 1 |
| Hata, Y | 1 |
| Mizumaki, K | 1 |
| Kinoshita, K | 1 |
| Nonobe, Y | 1 |
| Tabata, T | 1 |
| Sakamoto, T | 1 |
| Kataoka, N | 1 |
| Nakatani, Y | 1 |
| Ichida, F | 1 |
| Mori, H | 1 |
| Fukurotani, K | 1 |
| Inoue, H | 1 |
| Nishida, N | 1 |
| Li, W | 2 |
| Wang, QF | 2 |
| Du, R | 2 |
| Xu, QM | 1 |
| Ke, QM | 1 |
| Wang, B | 1 |
| Chen, XL | 1 |
| Tian, L | 2 |
| Zhang, SY | 1 |
| Kang, CL | 1 |
| Guan, SM | 1 |
| Yang, JG | 2 |
| Song, ZF | 2 |
| Huang, H | 1 |
| Millat, G | 1 |
| Rodriguez-Lafrasse, C | 1 |
| Rousson, R | 1 |
| Kugener, B | 1 |
| Chevalier, P | 1 |
| Chahine, M | 1 |
| Delisle, BP | 1 |
| Anderson, CL | 1 |
| Balijepalli, RC | 1 |
| Anson, BD | 1 |
| Kamp, TJ | 1 |
| January, CT | 1 |
| Bian, JS | 1 |
| Cui, J | 1 |
| Melman, Y | 1 |
| McDonald, TV | 1 |
| Tian, XL | 1 |
| Cheng, Y | 1 |
| Zhang, T | 1 |
| Liao, ML | 1 |
| Yong, SL | 1 |
| Wang, QK | 1 |
| Lai, LP | 1 |
| Deng, CL | 1 |
| Moss, AJ | 1 |
| Kass, RS | 1 |
| Liang, CS | 1 |
| Akimoto, K | 1 |
| Furutani, M | 1 |
| Imamura, S | 1 |
| Furutani, Y | 1 |
| Kasanuki, H | 1 |
| Takao, A | 1 |
| Momma, K | 1 |
| Matsuoka, R | 1 |
2 trials available for serine and Long QT Syndrome
| Article | Year |
|---|---|
Glycine/Serine polymorphism at position 38 influences KCNE1 subunit's modulatory actions on rapid and slow delayed rectifier K+ currents.
Topics: Amino Acid Substitution; Female; Glycine; HEK293 Cells; Humans; Ion Transport; Long QT Syndrome; Mal | 2014 |
Polymorphism of the gene encoding a human minimal potassium ion channel (minK).
Topics: Alleles; Animals; Base Sequence; Chromosomes, Human, Pair 11; Codon; DNA Primers; Genetic Carrier Sc | 1994 |
7 other studies available for serine and Long QT Syndrome
| Article | Year |
|---|---|
Congenital long QT syndrome caused by the F275S KCNQ1 mutation: mechanism of impaired channel function.
Topics: Animals; Cell Line; Endoplasmic Reticulum; Humans; KCNQ1 Potassium Channel; Long QT Syndrome; Mutati | 2009 |
Biophysical characterization of a new SCN5A mutation S1333Y in a SIDS infant linked to long QT syndrome.
Topics: Base Sequence; Cell Line; Electrophysiology; Humans; Infant; Ion Channel Gating; Long QT Syndrome; M | 2009 |
The G314S KCNQ1 mutation exerts a dominant-negative effect on expression of KCNQ1 channels in oocytes.
Topics: Action Potentials; Amino Acid Sequence; Animals; Electrophysiological Phenomena; Genes, Dominant; Gl | 2009 |
Thapsigargin selectively rescues the trafficking defective LQT2 channels G601S and F805C.
Topics: Amino Acid Substitution; Asparagine; Aspartic Acid; Cation Transport Proteins; Cell Line; Cell Membr | 2003 |
S641 contributes HERG K+ channel inactivation.
Topics: Amino Acid Sequence; Animals; Biophysics; CHO Cells; Cricetinae; Cricetulus; Electrophysiology; ERG1 | 2004 |
Optical mapping of ventricular arrhythmias in LQTS mice with SCN5A mutation N1325S.
Topics: Animals; Arrhythmias, Cardiac; Asparagine; Cardiac Complexes, Premature; Long QT Syndrome; Mexiletin | 2007 |
Novel missense mutation (G601S) of HERG in a Japanese long QT syndrome family.
Topics: Amino Acid Substitution; Cation Transport Proteins; Codon; DNA; DNA Mutational Analysis; DNA-Binding | 1998 |