serine has been researched along with Liver Steatosis in 6 studies
Serine: A non-essential amino acid occurring in natural form as the L-isomer. It is synthesized from GLYCINE or THREONINE. It is involved in the biosynthesis of PURINES; PYRIMIDINES; and other amino acids.
serine : An alpha-amino acid that is alanine substituted at position 3 by a hydroxy group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Sulpiride is an old antipsychotic still frequently used in many developing countries." | 5.48 | The antipsychotics sulpiride induces fatty liver in rats via phosphorylation of insulin receptor substrate-1 at Serine 307-mediated adipose tissue insulin resistance. ( Huang, X; Li, Y; Ren, L; Wang, C; Yu, Z; Zhou, X, 2018) |
| " In the methionine- and choline-deficient diet mouse model of steatohepatitis with CYP2E1 overexpression, insulin-induced IRS-1, IRS-2, and Akt phosphorylation were similarly decreased." | 3.73 | Hepatocyte CYP2E1 overexpression and steatohepatitis lead to impaired hepatic insulin signaling. ( Czaja, MJ; Rigoli, RM; Schattenberg, JM; Singh, R; Wang, Y, 2005) |
| "Sulpiride is an old antipsychotic still frequently used in many developing countries." | 1.48 | The antipsychotics sulpiride induces fatty liver in rats via phosphorylation of insulin receptor substrate-1 at Serine 307-mediated adipose tissue insulin resistance. ( Huang, X; Li, Y; Ren, L; Wang, C; Yu, Z; Zhou, X, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (33.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (33.33) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 1 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Yokobori, K | 1 |
| Gruzdev, A | 1 |
| Negishi, M | 1 |
| Zhou, X | 1 |
| Ren, L | 1 |
| Yu, Z | 1 |
| Huang, X | 1 |
| Li, Y | 1 |
| Wang, C | 1 |
| Dasarathy, S | 1 |
| Kasumov, T | 1 |
| Edmison, JM | 1 |
| Gruca, LL | 1 |
| Bennett, C | 1 |
| Duenas, C | 1 |
| Marczewski, S | 1 |
| McCullough, AJ | 1 |
| Hanson, RW | 1 |
| Kalhan, SC | 1 |
| Schattenberg, JM | 1 |
| Wang, Y | 1 |
| Singh, R | 1 |
| Rigoli, RM | 1 |
| Czaja, MJ | 1 |
| Aoyama, Y | 1 |
| Yasui, H | 1 |
| Ashida, K | 1 |
| Fallon, HJ | 1 |
| Pesch, LA | 1 |
| Klatskin, G | 1 |
6 other studies available for serine and Liver Steatosis
| Article | Year |
|---|---|
Mice blocking Ser347 phosphorylation of pregnane x receptor develop hepatic fasting-induced steatosis and hypertriglyceridemia.
Topics: Animals; Fasting; Fatty Liver; Hypertriglyceridemia; Liver; Mice; Phosphorylation; Pregnane X Recept | 2022 |
The antipsychotics sulpiride induces fatty liver in rats via phosphorylation of insulin receptor substrate-1 at Serine 307-mediated adipose tissue insulin resistance.
Topics: Adipose Tissue; Animals; Antipsychotic Agents; Fatty Liver; Insulin Receptor Substrate Proteins; Ins | 2018 |
Glycine and urea kinetics in nonalcoholic steatohepatitis in human: effect of intralipid infusion.
Topics: 3-Hydroxybutyric Acid; Adult; Aged; Case-Control Studies; Cystathionine; Fasting; Fat Emulsions, Int | 2009 |
Hepatocyte CYP2E1 overexpression and steatohepatitis lead to impaired hepatic insulin signaling.
Topics: Adenoviridae; Animals; Blotting, Northern; Blotting, Western; Cell Line; Choline; Cytochrome P-450 C | 2005 |
Effect of dietary protein and amino acids in a choline-deficient diet on lipid accumulation in rat liver.
Topics: Amino Acids; Animal Nutritional Physiological Phenomena; Animals; Body Composition; Body Weight; Cas | 1971 |
Alterations in phospholipid metabolism induced by ethanol administration.
Topics: Alkylation; Animals; Choline; Chromatography, Thin Layer; Ethanol; Fatty Liver; Formates; In Vitro T | 1965 |