serine has been researched along with Liver Cirrhosis in 12 studies
Serine: A non-essential amino acid occurring in natural form as the L-isomer. It is synthesized from GLYCINE or THREONINE. It is involved in the biosynthesis of PURINES; PYRIMIDINES; and other amino acids.
serine : An alpha-amino acid that is alanine substituted at position 3 by a hydroxy group.
Liver Cirrhosis: Liver disease in which the normal microcirculation, the gross vascular anatomy, and the hepatic architecture have been variably destroyed and altered with fibrous septa surrounding regenerated or regenerating parenchymal nodules.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A selective mutation, an arginine-to-serine substitution in codon 249, of the p53 gene has been identified as a "hotspot" mutation in hepatocellular carcinoma (HCC)." | 3.70 | Ser-249 p53 mutations in plasma DNA of patients with hepatocellular carcinoma from The Gambia. ( Bréchot, C; Camus-Randon, AM; Goedert, JJ; Hainaut, P; Kirk, GD; Mendy, M; Merle, P; Montesano, R; Trépo, C, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (33.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (25.00) | 29.6817 |
| 2010's | 1 (8.33) | 24.3611 |
| 2020's | 4 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Nyamsuren, G | 1 |
| Rapp, G | 1 |
| Dihazi, H | 1 |
| Zeisberg, EM | 1 |
| Tampe, D | 1 |
| Tampe, B | 1 |
| Zeisberg, M | 1 |
| Creeden, JF | 1 |
| Kipp, ZA | 1 |
| Xu, M | 1 |
| Flight, RM | 1 |
| Moseley, HNB | 1 |
| Martinez, GJ | 1 |
| Lee, WH | 1 |
| Alganem, K | 1 |
| Imami, AS | 1 |
| McMullen, MR | 1 |
| Roychowdhury, S | 1 |
| Nawabi, AM | 1 |
| Hipp, JA | 1 |
| Softic, S | 1 |
| Weinman, SA | 1 |
| McCullumsmith, R | 1 |
| Nagy, LE | 1 |
| Hinds, TD | 1 |
| Du, ZX | 1 |
| Li, Y | 1 |
| Wang, ZJ | 1 |
| Zhou, DM | 1 |
| Yang, JH | 1 |
| Ise, H | 1 |
| Araki, Y | 1 |
| Song, I | 1 |
| Akatsuka, G | 1 |
| Moles, A | 1 |
| Sanchez, AM | 1 |
| Banks, PS | 1 |
| Murphy, LB | 1 |
| Luli, S | 1 |
| Borthwick, L | 1 |
| Fisher, A | 1 |
| O'Reilly, S | 1 |
| van Laar, JM | 1 |
| White, SA | 1 |
| Perkins, ND | 1 |
| Burt, AD | 1 |
| Mann, DA | 1 |
| Oakley, F | 1 |
| PLAUCHU, M | 1 |
| KNAUFF, HG | 1 |
| SEYBOLD, D | 1 |
| MILLER, B | 1 |
| Grossman, CE | 1 |
| Niland, B | 1 |
| Stancato, C | 1 |
| Verhoeven, NM | 1 |
| Van Der Knaap, MS | 1 |
| Jakobs, C | 1 |
| Brown, LM | 1 |
| Vajda, S | 1 |
| Banki, K | 1 |
| Perl, A | 1 |
| Shi, Y | 1 |
| Li, J | 1 |
| Liang, LC | 1 |
| Wu, YS | 1 |
| Zhou, YS | 1 |
| Chen, XY | 1 |
| Chen, DX | 1 |
| Wu, H | 1 |
| Kirk, GD | 1 |
| Camus-Randon, AM | 1 |
| Mendy, M | 1 |
| Goedert, JJ | 1 |
| Merle, P | 1 |
| Trépo, C | 1 |
| Bréchot, C | 1 |
| Hainaut, P | 1 |
| Montesano, R | 1 |
| Jenkins, DJ | 1 |
| Shapira, N | 1 |
| Greenberg, G | 1 |
| Jenkins, AL | 1 |
| Collier, GR | 1 |
| Poduch, C | 1 |
| Wolever, TM | 1 |
| Anderson, GH | 1 |
| Blendis, LM | 1 |
| Battesti, JP | 1 |
| Thuillier, A | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Pilot Study of Changes in Circulating Tumor-Specific DNA (ctDNA) in Patients With Non-Metastatic Non-Small Cell Lung Cancer[NCT03746262] | 40 participants (Actual) | Observational | 2016-05-13 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
12 other studies available for serine and Liver Cirrhosis
| Article | Year |
|---|---|
PP2A phosphatase inhibition is anti-fibrotic through Ser77 phosphorylation-mediated ARNT/ARNT homodimer formation.
Topics: Amino Acid Sequence; Animals; Aryl Hydrocarbon Receptor Nuclear Translocator; Biomarkers; Disease Mo | 2021 |
Hepatic kinome atlas: An in-depth identification of kinase pathways in liver fibrosis of humans and rodents.
Topics: Animals; Collagen; Discoidin Domain Receptors; Fibrosis; Humans; Liver; Liver Cirrhosis; Liver Disea | 2022 |
[Bioinformatics analysis of differentially expressed genes associated with chronic schistosomiasis japonica-induced hepatic fibrosis].
Topics: Adenosine Monophosphate; Calcium; Coenzyme A; Computational Biology; Fatty Acids; Humans; Liver Cirr | 2022 |
N-acetylglucosamine-bearing polymers mimicking O-GlcNAc-modified proteins elicit anti-fibrotic activities in myofibroblasts and activated stellate cells.
Topics: Acetylglucosamine; Animals; Biomimetic Materials; Carbon Tetrachloride; Desmin; Hepatic Stellate Cel | 2023 |
Inhibition of RelA-Ser536 phosphorylation by a competing peptide reduces mouse liver fibrosis without blocking the innate immune response.
Topics: Adult; Animals; Carbon Tetrachloride Poisoning; Fibroblasts; Humans; I-kappa B Kinase; Immunity, Inn | 2013 |
[Prognostic value of the serum serine level in alcoholic cirrhosis. Attempted comparison with the prothrombin level].
Topics: Alcoholism; Hematologic Tests; Hemostatics; Humans; Liver Cirrhosis; Liver Cirrhosis, Alcoholic; Pro | 1960 |
[FREE PLASMA AMINO ACIDS IN LIVER CIRRHOSIS AND HEPATITIS].
Topics: Alanine; Amino Acids; Blood; Chromatography; Glutamine; Glycine; Hepatitis; Humans; Ion Exchange Res | 1964 |
Deletion of Ser-171 causes inactivation, proteasome-mediated degradation and complete deficiency of human transaldolase.
Topics: Cells, Cultured; Child; Enzyme Activation; Enzyme Inhibitors; Female; Fibroblasts; Gene Expression R | 2004 |
[Expression of K18, Ser-33 and Ser-52 phosphorylated K18 in HBV infected human liver disease and its significance].
Topics: Hepatitis B; Humans; Immunohistochemistry; Keratin-18; Liver Cirrhosis; Liver Diseases; Phosphorylat | 2007 |
Ser-249 p53 mutations in plasma DNA of patients with hepatocellular carcinoma from The Gambia.
Topics: Adult; Aflatoxins; Aged; Aged, 80 and over; Arginine; Black People; Carcinoma, Hepatocellular; Case- | 2000 |
Low glycemic index foods and reduced glucose, amino acid, and endocrine responses in cirrhosis.
Topics: Aged; Amino Acids; Blood Glucose; Dietary Carbohydrates; Female; Humans; Insulin; Leucine; Liver Cir | 1989 |
[Folic acid deficiencies. Etiology and biological diagnosis].
Topics: Alcoholic Intoxication; Anticonvulsants; Antimetabolites; Celiac Disease; Chromatography; Enterococc | 1968 |