serine and Lipidoses
serine has been researched along with Lipidoses in 6 studies
Serine: A non-essential amino acid occurring in natural form as the L-isomer. It is synthesized from GLYCINE or THREONINE. It is involved in the biosynthesis of PURINES; PYRIMIDINES; and other amino acids.
serine : An alpha-amino acid that is alanine substituted at position 3 by a hydroxy group.
Lipidoses: Conditions characterized by abnormal lipid deposition due to disturbance in lipid metabolism, such as hereditary diseases involving lysosomal enzymes required for lipid breakdown. They are classified either by the enzyme defect or by the type of lipid involved.
Research Excerpts
| Excerpt | Relevance | Reference |
|---|---|---|
| "N,N-Diethyl-2-[4-(phenylmethyl)phenoxy]ethanamine (DPPE, tesmilifene), a potent chemopotentiating drug currently in Phase III clinical trials of metastatic breast cancer, increases cytotoxicity of anthracyclines and taxanes in a variety of multi-drug resistance expressing (MDR+) tumor cell lines in vitro; inhibits binding of histamine to CYP3A4, a lipid/prostanoid-regulatory P450; and modulates serum levels of HDL/LDL cholesterol and phospholipids in vivo." | 3.74 | The phospholipidosis-lnducing potential of the chemopotentiating drug, N,N-Diethyl-2-[4-(phenylmethyl)phenoxy]ethanamine (DPPE, tesmilifene) correlates with its stimulation of phosphatidylserine synthesis and exposure on the plasma membrane in MCF-7 breas ( Brandes, L; Hatch, GM; Queen, G; Xu, FY, 2007) |
Research
Studies (6)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (50.00) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 2 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Xu, FY | 1 |
| Queen, G | 1 |
| Brandes, L | 1 |
| Hatch, GM | 1 |
| Miller, WL | 1 |
| Dai, ZQ | 1 |
| Yu, YG | 1 |
| Zhu, PP | 1 |
| Yuan, XJ | 1 |
| Xu, JY | 1 |
| Li, XY | 1 |
| Touster, O | 1 |
| Den, H | 1 |
| Kaufman, B | 1 |
| Roseman, S | 1 |
| Balint, JA | 1 |
| Kyriakides, EC | 1 |
Reviews
2 reviews available for serine and Lipidoses
| Article | Year |
|---|---|
Androgen biosynthesis from cholesterol to DHEA.
Topics: Adrenal Glands; Adrenal Hyperplasia, Congenital; Androgens; Animals; Cholesterol; Cholesterol Side-C | 2002 |
Some aspects of the cellular biochemistry of lysosomal and related glycosidases.
Topics: Animals; Carbohydrate Metabolism, Inborn Errors; Diffuse Cerebral Sclerosis of Schilder; Fucose; Gal | 1973 |
Other Studies
4 other studies available for serine and Lipidoses
| Article | Year |
|---|---|
The phospholipidosis-lnducing potential of the chemopotentiating drug, N,N-Diethyl-2-[4-(phenylmethyl)phenoxy]ethanamine (DPPE, tesmilifene) correlates with its stimulation of phosphatidylserine synthesis and exposure on the plasma membrane in MCF-7 breas
Topics: Antineoplastic Agents; Arachidonic Acid; Breast Neoplasms; Cell Line, Tumor; Cell Membrane; Drug Syn | 2007 |
Effect of L-4-oxalysine on ultrastructures of liver cells in mice.
Topics: Amino Acids, Dicarboxylic; Animals; Endoplasmic Reticulum; Female; Lipidoses; Liver; Mice; Mitochond | 1991 |
Properties of some glycosyltransferases in embryonic chicken brain.
Topics: Aging; Albumins; Amniotic Fluid; Animals; Brain; Carbon Isotopes; Chick Embryo; Cytosine Nucleotides | 1970 |
Studies of red cell stromal proteins in Tay-Sachs disease.
Topics: Adolescent; Adult; Amino Acids; Cell Membrane; Child, Preschool; Erythrocytes; Female; Glycoproteins | 1968 |