serine has been researched along with Leukodystrophy, Metachromatic in 3 studies
Serine: A non-essential amino acid occurring in natural form as the L-isomer. It is synthesized from GLYCINE or THREONINE. It is involved in the biosynthesis of PURINES; PYRIMIDINES; and other amino acids.
serine : An alpha-amino acid that is alanine substituted at position 3 by a hydroxy group.
Leukodystrophy, Metachromatic: An autosomal recessive metabolic disease caused by a deficiency of CEREBROSIDE-SULFATASE leading to intralysosomal accumulation of cerebroside sulfate (SULFOGLYCOSPHINGOLIPIDS) in the nervous system and other organs. Pathological features include diffuse demyelination, and metachromatically-staining granules in many cell types such as the GLIAL CELLS. There are several allelic and nonallelic forms with a variety of neurological symptoms.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Honke, K | 1 |
| Kobayashi, T | 1 |
| Fujii, T | 1 |
| Gasa, S | 1 |
| Xu, M | 1 |
| Takamaru, Y | 1 |
| Kondo, R | 1 |
| Tsuji, S | 1 |
| Makita, A | 1 |
| Kreysing, J | 1 |
| Bohne, W | 1 |
| Bösenberg, C | 1 |
| Marchesini, S | 1 |
| Turpin, JC | 1 |
| Baumann, N | 1 |
| von Figura, K | 1 |
| Gieselmann, V | 1 |
| Touster, O | 1 |
1 review available for serine and Leukodystrophy, Metachromatic
| Article | Year |
|---|---|
Some aspects of the cellular biochemistry of lysosomal and related glycosidases.
Topics: Animals; Carbohydrate Metabolism, Inborn Errors; Diffuse Cerebral Sclerosis of Schilder; Fucose; Gal | 1973 |
2 other studies available for serine and Leukodystrophy, Metachromatic
| Article | Year |
|---|---|
An adult-type metachromatic leukodystrophy caused by substitution of serine for glycine-122 in arylsulfatase A.
Topics: Adult; Animals; Base Sequence; Cell Line; Cerebroside-Sulfatase; Chlorocebus aethiops; DNA Mutationa | 1993 |
High residual arylsulfatase A (ARSA) activity in a patient with late-infantile metachromatic leukodystrophy.
Topics: Alleles; Animals; Base Sequence; Cells, Cultured; Cerebroside-Sulfatase; Cricetinae; DNA Mutational | 1993 |