serine has been researched along with Leukemia L 1210 in 13 studies
Serine: A non-essential amino acid occurring in natural form as the L-isomer. It is synthesized from GLYCINE or THREONINE. It is involved in the biosynthesis of PURINES; PYRIMIDINES; and other amino acids.
serine : An alpha-amino acid that is alanine substituted at position 3 by a hydroxy group.
| Excerpt | Relevance | Reference |
|---|---|---|
| " P247-71(ATCC 53709)produced a novel antibiotic eponemycin which exhibited specific in vivo antitumor effect against B16 melanoma." | 7.68 | Eponemycin, a new antibiotic active against B16 melanoma. I. Production, isolation, structure and biological activity. ( Hatori, M; Kamei, H; Konishi, M; Nishiyama, Y; Oki, T; Sugawara, K; Tomita, K, 1990) |
| " P247-71(ATCC 53709)produced a novel antibiotic eponemycin which exhibited specific in vivo antitumor effect against B16 melanoma." | 3.68 | Eponemycin, a new antibiotic active against B16 melanoma. I. Production, isolation, structure and biological activity. ( Hatori, M; Kamei, H; Konishi, M; Nishiyama, Y; Oki, T; Sugawara, K; Tomita, K, 1990) |
| " The concrete models of this reaction complex as well as methotrexate transport into the leukemia L 1210 and Ehrlich ascite tumour cells and the dynamic inhibition of the target enzyme--dihydrofolate reductase--by methotrexate have been described and investigated." | 3.66 | [Mathematical description and study of the folic acid cycle reactions]. ( Belousova, AK; Gerasimova, GK; Greshilov, MM; Vorontsov, IN, 1980) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (84.62) | 18.7374 |
| 1990's | 2 (15.38) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| OCHOA, M | 1 |
| WEINSTEIN, IB | 1 |
| Belousova, AK | 2 |
| Gerasimova, GK | 2 |
| Vorontsov, IN | 2 |
| Greshilov, MM | 2 |
| Scanlon, KJ | 2 |
| Cashmore, AR | 2 |
| Moroson, BA | 2 |
| Dreyer, RN | 2 |
| Bertino, JR | 2 |
| Zhao, R | 1 |
| Gao, F | 1 |
| Goldman, ID | 1 |
| Vistica, DT | 1 |
| Schuette, B | 1 |
| Kumar, PM | 1 |
| North, JA | 1 |
| Mangum, JH | 1 |
| Rao, NA | 1 |
| Sugawara, K | 1 |
| Hatori, M | 1 |
| Nishiyama, Y | 1 |
| Tomita, K | 1 |
| Kamei, H | 1 |
| Konishi, M | 1 |
| Oki, T | 1 |
| Kashani-Sabet, M | 1 |
| Pallai, M | 1 |
| Saketos, M | 1 |
| Jackson, RC | 1 |
| Harrap, KR | 1 |
| Groth, DP | 1 |
| D'Angelo, JM | 1 |
| Vogler, WR | 1 |
| Mingioli, ES | 1 |
| Betz, B | 1 |
| O'Brien, P | 1 |
| McCullough, JL | 1 |
| Gerchakov, S | 1 |
| Schultz, HP | 1 |
13 other studies available for serine and Leukemia L 1210
| Article | Year |
|---|---|
AMINO ACID CODING IN A SUBCELLULAR SYSTEM DERIVED FROM THE L1210 MOUSE ASCITES LEUKEMIA.
Topics: Adenine Nucleotides; Amino Acids; Animals; Ascites; Genetic Code; Isoleucine; Leucine; Leukemia L121 | 1964 |
[Evaluation of biochemical criteria for sensitivity of tumor cells to methotrexate by means of mathematic simulation].
Topics: Animals; Carcinoma, Ehrlich Tumor; Folic Acid; Kinetics; Leukemia L1210; Mathematics; Methionine; Me | 1980 |
[Mathematical description and study of the folic acid cycle reactions].
Topics: Animals; Biological Transport; Carcinoma, Ehrlich Tumor; Folic Acid; Humans; Kinetics; Leukemia L121 | 1980 |
Inhibition of serine metabolism by tetrahydrohomofolate in L1210 mouse leukemia cells.
Topics: Animals; Cell Division; Cells, Cultured; Folic Acid; Glycine Hydroxymethyltransferase; Leukemia L121 | 1981 |
Discrimination among reduced folates and methotrexate as transport substrates by a phenylalanine substitution for serine within the predicted eighth transmembrane domain of the reduced folate carrier.
Topics: Amino Acid Substitution; Animals; Antimetabolites, Antineoplastic; Biological Transport; Carrier Pro | 1999 |
Substrate specificity of a high-affinity, monovalent cation-dependent amino acid carrier.
Topics: Alanine; Amino Acids; Animals; Biological Transport; Leucine; Leukemia L1210; Lithium; Mice; Potassi | 1979 |
Cooperative interactions of tetrahydrofolate with purified pig kidney serine transhydroxymethylase and loss of this cooperativity in L1210 tumors and in tissues of mice bearing these tumors.
Topics: Allosteric Regulation; Allosteric Site; Animals; Binding Sites; Glycine Hydroxymethyltransferase; Ki | 1976 |
Eponemycin, a new antibiotic active against B16 melanoma. I. Production, isolation, structure and biological activity.
Topics: Amides; Animals; Antibiotics, Antineoplastic; DNA, Neoplasm; Fermentation; Humans; Leukemia L1210; L | 1990 |
Inhibition of methionine uptake by methotrexate in mouse leukemia L1210 cells.
Topics: Animals; Biological Transport, Active; Cell Line; Depression, Chemical; Leukemia L1210; Methionine; | 1987 |
Studies with a mathematical model of folate metabolism.
Topics: Animals; Cells, Cultured; Dose-Response Relationship, Drug; Floxuridine; Folic Acid; Formates; Glyci | 1973 |
Selective metabolic effects of 1,3-bis(2-chloroethyl)-1-nitrosourea upon de novo purine biosynthesis.
Topics: Acute Disease; Amino Acids; Animals; Antineoplastic Agents; Ascitic Fluid; Carbon Isotopes; Carcinom | 1971 |
Inhibition of growth of leukemia cells by enzymic folate depletion.
Topics: Animals; Carboxypeptidases; Carcinoma 256, Walker; Cell Line; Culture Media; Depression, Chemical; F | 1971 |
Quinoxaline studies. XIV. Potential anticancer agents. Some quinoxaline amino acid and dipeptide derivatives related to quinoxaline antibiotics.
Topics: Alanine; Amino Acids; Animals; Antineoplastic Agents; Chemical Phenomena; Chemistry; Dipeptides; Gly | 1969 |