Page last updated: 2024-11-08

serine and Leukemia, Myeloid, Acute

serine has been researched along with Leukemia, Myeloid, Acute in 20 studies

Serine: A non-essential amino acid occurring in natural form as the L-isomer. It is synthesized from GLYCINE or THREONINE. It is involved in the biosynthesis of PURINES; PYRIMIDINES; and other amino acids.
serine : An alpha-amino acid that is alanine substituted at position 3 by a hydroxy group.

Leukemia, Myeloid, Acute: Clonal expansion of myeloid blasts in bone marrow, blood, and other tissue. Myeloid leukemias develop from changes in cells that normally produce NEUTROPHILS; BASOPHILS; EOSINOPHILS; and MONOCYTES.

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19901 (5.00)18.7374
1990's0 (0.00)18.2507
2000's4 (20.00)29.6817
2010's8 (40.00)24.3611
2020's7 (35.00)2.80

Authors

AuthorsStudies
Kramer, MH1
Zhang, Q1
Sprung, R1
Day, RB1
Erdmann-Gilmore, P1
Li, Y1
Xu, Z1
Helton, NM1
George, DR1
Mi, Y1
Westervelt, P1
Payton, JE1
Ramakrishnan, SM1
Miller, CA1
Link, DC1
DiPersio, JF1
Walter, MJ1
Townsend, RR1
Ley, TJ1
Murray, HC1
Miller, K1
Brzozowski, JS1
Kahl, RGS1
Smith, ND1
Humphrey, SJ1
Dun, MD1
Verrills, NM1
Paredes, R1
Kelly, JR1
Geary, B1
Almarzouq, B1
Schneider, M1
Pearson, S1
Narayanan, P1
Williamson, A1
Lovell, SC1
Wiseman, DH1
Chadwick, JA1
Jones, NJ1
Kustikova, O1
Schambach, A1
Garner, T1
Amaral, FMR1
Pierce, A1
Stevens, A1
Somervaille, TCP1
Whetton, AD1
Meyer, S1
Jeong, S1
Savino, AM1
Chirayil, R1
Barin, E1
Cheng, Y1
Park, SM1
Schurer, A1
Mullarky, E1
Cantley, LC1
Kharas, MG1
Keshari, KR1
Bjelosevic, S1
Gruber, E1
Newbold, A1
Shembrey, C1
Devlin, JR1
Hogg, SJ1
Kats, L1
Todorovski, I1
Fan, Z1
Abrehart, TC1
Pomilio, G1
Wei, A1
Gregory, GP1
Vervoort, SJ1
Brown, KK1
Johnstone, RW1
Thacker, G1
Mishra, M1
Sharma, A1
Singh, AK1
Sanyal, S1
Trivedi, AK1
Di Marcantonio, D1
Martinez, E1
Kanefsky, JS1
Huhn, JM1
Gabbasov, R1
Gupta, A1
Krais, JJ1
Peri, S1
Tan, Y1
Skorski, T1
Dorrance, A1
Garzon, R1
Goldman, AR1
Tang, HY1
Johnson, N1
Sykes, SM1
Takami, M1
Katayama, K1
Noguchi, K1
Sugimoto, Y1
Yuan, LL1
Green, AS2
Bertoli, S1
Grimal, F1
Mansat-De Mas, V1
Dozier, C1
Tamburini, J2
Récher, C2
Didier, C1
Manenti, S1
Brault, L1
Rovó, A1
Decker, S1
Dierks, C1
Tzankov, A1
Schwaller, J1
Natarajan, K1
Xie, Y1
Burcu, M1
Linn, DE1
Qiu, Y1
Baer, MR1
Huang, Y1
Thoms, JA1
Tursky, ML1
Knezevic, K1
Beck, D1
Chandrakanthan, V1
Suryani, S1
Olivier, J1
Boulton, A1
Glaros, EN1
Thomas, SR1
Lock, RB1
MacKenzie, KL1
Bushweller, JH1
Wong, JW1
Pimanda, JE1
Gallay, N1
Dos Santos, C1
Cuzin, L1
Bousquet, M1
Simmonet Gouy, V1
Chaussade, C1
Attal, M1
Payrastre, B1
Demur, C1
Chapuis, N1
Park, S1
Leotoing, L1
Verdier, F1
Bardet, V1
Willems, L1
Agou, F1
Ifrah, N1
Dreyfus, F1
Bismuth, G1
Baud, V1
Lacombe, C1
Mayeux, P1
Bouscary, D1
Fragliasso, V1
Chiodo, Y1
Ferrari-Amorotti, G1
Soliera, AR1
Manzotti, G1
Cattelani, S1
Candini, O1
Grisendi, G1
Vergalli, J1
Mariani, SA1
Guerzoni, C1
Calabretta, B1
Radomska, HS2
Alberich-Jordà, M1
Will, B1
Gonzalez, D1
Delwel, R1
Tenen, DG2
Simone, F1
Luo, RT1
Polak, PE1
Kaberlein, JJ1
Thirman, MJ1
Bassères, DS1
Zheng, R1
Zhang, P1
Dayaram, T1
Yamamoto, Y1
Sternberg, DW1
Lokker, N1
Giese, NA1
Bohlander, SK1
Schnittger, S1
Delmotte, MH1
Davis, RJ1
Small, D1
Hiddemann, W1
Gilliland, DG1
Odgerel, T1
Kikuchi, J1
Wada, T1
Shimizu, R1
Futaki, K1
Kano, Y1
Furukawa, Y1
Dimitrov, NV1
Hansz, J1
Toth, MA1
Bartolotta, B1

Other Studies

20 other studies available for serine and Leukemia, Myeloid, Acute

ArticleYear
Proteomic and phosphoproteomic landscapes of acute myeloid leukemia.
    Blood, 2022, 09-29, Volume: 140, Issue:13

    Topics: fms-Like Tyrosine Kinase 3; Histone Demethylases; Humans; Jumonji Domain-Containing Histone Demethyl

2022
Synergistic Targeting of DNA-PK and KIT Signaling Pathways in KIT Mutant Acute Myeloid Leukemia.
    Molecular & cellular proteomics : MCP, 2023, Volume: 22, Issue:3

    Topics: Animals; Apoptosis; Cell Line, Tumor; Dasatinib; DNA; DNA-Activated Protein Kinase; Leukemia, Myeloi

2023
EVI1 phosphorylation at S436 regulates interactions with CtBP1 and DNMT3A and promotes self-renewal.
    Cell death & disease, 2020, 10-20, Volume: 11, Issue:10

    Topics: Alcohol Oxidoreductases; Cell Self Renewal; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; D

2020
High Fructose Drives the Serine Synthesis Pathway in Acute Myeloid Leukemic Cells.
    Cell metabolism, 2021, 01-05, Volume: 33, Issue:1

    Topics: Animals; Fructose; Humans; Leukemia, Myeloid, Acute; Mice; Mice, Congenic; Mice, Inbred NOD; Serine;

2021
Serine Biosynthesis Is a Metabolic Vulnerability in FLT3-ITD-Driven Acute Myeloid Leukemia.
    Cancer discovery, 2021, Volume: 11, Issue:6

    Topics: Animals; Cell Line, Tumor; Disease Models, Animal; fms-Like Tyrosine Kinase 3; Humans; Leukemia, Mye

2021
CDK2-instigates C/EBPα degradation through SKP2 in Acute myeloid leukemia.
    Medical oncology (Northwood, London, England), 2021, May-17, Volume: 38, Issue:6

    Topics: CCAAT-Enhancer-Binding Proteins; Cell Differentiation; Cell Line, Tumor; Cyclin-Dependent Kinase 2;

2021
ATF3 coordinates serine and nucleotide metabolism to drive cell cycle progression in acute myeloid leukemia.
    Molecular cell, 2021, 07-01, Volume: 81, Issue:13

    Topics: Activating Transcription Factor 3; Cell Cycle; Cell Line, Tumor; Humans; Leukemia, Myeloid, Acute; N

2021
Protein kinase C alpha-mediated phosphorylation of PIM-1L promotes the survival and proliferation of acute myeloid leukemia cells.
    Biochemical and biophysical research communications, 2018, 09-10, Volume: 503, Issue:3

    Topics: Apoptosis; Cell Line, Tumor; Cell Proliferation; Humans; Leukemia, Myeloid, Acute; Phosphorylation;

2018
Pim kinases phosphorylate Chk1 and regulate its functions in acute myeloid leukemia.
    Leukemia, 2014, Volume: 28, Issue:2

    Topics: Cell Line, Tumor; Checkpoint Kinase 1; fms-Like Tyrosine Kinase 3; Gene Duplication; Humans; Intrace

2014
CXCR4-SERINE339 regulates cellular adhesion, retention and mobilization, and is a marker for poor prognosis in acute myeloid leukemia.
    Leukemia, 2014, Volume: 28, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Biomarkers; Cell Adhesion; Female; Humans; Leukemia, Myeloid, Acute;

2014
Pim-1 kinase phosphorylates and stabilizes 130 kDa FLT3 and promotes aberrant STAT5 signaling in acute myeloid leukemia with FLT3 internal tandem duplication.
    PloS one, 2013, Volume: 8, Issue:9

    Topics: Animals; Apoptosis; Calnexin; Cell Line; Cell Proliferation; Endoplasmic Reticulum; fms-Like Tyrosin

2013
MAPK/ERK2 phosphorylates ERG at serine 283 in leukemic cells and promotes stem cell signatures and cell proliferation.
    Leukemia, 2016, Volume: 30, Issue:7

    Topics: Binding Sites; Cell Line, Tumor; Cell Proliferation; Hematopoietic Stem Cells; Humans; Leukemia; Leu

2016
The level of AKT phosphorylation on threonine 308 but not on serine 473 is associated with high-risk cytogenetics and predicts poor overall survival in acute myeloid leukaemia.
    Leukemia, 2009, Volume: 23, Issue:6

    Topics: Adolescent; Adult; Apoptosis; Cell Proliferation; Cytogenetic Analysis; Female; Humans; Leukemia, My

2009
IκB kinase overcomes PI3K/Akt and ERK/MAPK to control FOXO3a activity in acute myeloid leukemia.
    Blood, 2010, Nov-18, Volume: 116, Issue:20

    Topics: Apoptosis; Cell Nucleus; Cell Proliferation; Extracellular Signal-Regulated MAP Kinases; Forkhead Bo

2010
Phosphorylation of serine 21 modulates the proliferation inhibitory more than the differentiation inducing effects of C/EBPα in K562 cells.
    Journal of cellular biochemistry, 2012, Volume: 113, Issue:5

    Topics: Amino Acid Substitution; Base Sequence; Benzamides; CCAAT-Enhancer-Binding Protein-alpha; Cell Diffe

2012
Targeting CDK1 promotes FLT3-activated acute myeloid leukemia differentiation through C/EBPα.
    The Journal of clinical investigation, 2012, Volume: 122, Issue:8

    Topics: Animals; Base Sequence; CCAAT-Enhancer-Binding Protein-alpha; CDC2 Protein Kinase; Cell Differentiat

2012
ELL-associated factor 2 (EAF2), a functional homolog of EAF1 with alternative ELL binding properties.
    Blood, 2003, Mar-15, Volume: 101, Issue:6

    Topics: Amino Acid Sequence; Animals; Aspartic Acid; Binding Sites; Blotting, Northern; Bone Marrow; Cell Nu

2003
Block of C/EBP alpha function by phosphorylation in acute myeloid leukemia with FLT3 activating mutations.
    The Journal of experimental medicine, 2006, Feb-20, Volume: 203, Issue:2

    Topics: Aged; CCAAT-Enhancer-Binding Protein-alpha; Cell Differentiation; Cell Line; Enzyme Activation; Fema

2006
The FLT3 inhibitor PKC412 exerts differential cell cycle effects on leukemic cells depending on the presence of FLT3 mutations.
    Oncogene, 2008, May-15, Volume: 27, Issue:22

    Topics: Apoptosis; bcl-Associated Death Protein; CDC2 Protein Kinase; Cell Cycle; Cell Line, Tumor; Cell Pro

2008
Serine and aspartic acid metabolism in leukemic leukocytes: correlation to effectiveness of therapy.
    Blood, 1971, Volume: 38, Issue:5

    Topics: Adult; Aged; Aspartic Acid; Blood Proteins; Carbon Dioxide; Carbon Isotopes; Female; Glycine; Humans

1971