serine has been researched along with Leukemia, Myeloid, Acute in 20 studies
Serine: A non-essential amino acid occurring in natural form as the L-isomer. It is synthesized from GLYCINE or THREONINE. It is involved in the biosynthesis of PURINES; PYRIMIDINES; and other amino acids.
serine : An alpha-amino acid that is alanine substituted at position 3 by a hydroxy group.
Leukemia, Myeloid, Acute: Clonal expansion of myeloid blasts in bone marrow, blood, and other tissue. Myeloid leukemias develop from changes in cells that normally produce NEUTROPHILS; BASOPHILS; EOSINOPHILS; and MONOCYTES.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (5.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (20.00) | 29.6817 |
| 2010's | 8 (40.00) | 24.3611 |
| 2020's | 7 (35.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kramer, MH | 1 |
| Zhang, Q | 1 |
| Sprung, R | 1 |
| Day, RB | 1 |
| Erdmann-Gilmore, P | 1 |
| Li, Y | 1 |
| Xu, Z | 1 |
| Helton, NM | 1 |
| George, DR | 1 |
| Mi, Y | 1 |
| Westervelt, P | 1 |
| Payton, JE | 1 |
| Ramakrishnan, SM | 1 |
| Miller, CA | 1 |
| Link, DC | 1 |
| DiPersio, JF | 1 |
| Walter, MJ | 1 |
| Townsend, RR | 1 |
| Ley, TJ | 1 |
| Murray, HC | 1 |
| Miller, K | 1 |
| Brzozowski, JS | 1 |
| Kahl, RGS | 1 |
| Smith, ND | 1 |
| Humphrey, SJ | 1 |
| Dun, MD | 1 |
| Verrills, NM | 1 |
| Paredes, R | 1 |
| Kelly, JR | 1 |
| Geary, B | 1 |
| Almarzouq, B | 1 |
| Schneider, M | 1 |
| Pearson, S | 1 |
| Narayanan, P | 1 |
| Williamson, A | 1 |
| Lovell, SC | 1 |
| Wiseman, DH | 1 |
| Chadwick, JA | 1 |
| Jones, NJ | 1 |
| Kustikova, O | 1 |
| Schambach, A | 1 |
| Garner, T | 1 |
| Amaral, FMR | 1 |
| Pierce, A | 1 |
| Stevens, A | 1 |
| Somervaille, TCP | 1 |
| Whetton, AD | 1 |
| Meyer, S | 1 |
| Jeong, S | 1 |
| Savino, AM | 1 |
| Chirayil, R | 1 |
| Barin, E | 1 |
| Cheng, Y | 1 |
| Park, SM | 1 |
| Schurer, A | 1 |
| Mullarky, E | 1 |
| Cantley, LC | 1 |
| Kharas, MG | 1 |
| Keshari, KR | 1 |
| Bjelosevic, S | 1 |
| Gruber, E | 1 |
| Newbold, A | 1 |
| Shembrey, C | 1 |
| Devlin, JR | 1 |
| Hogg, SJ | 1 |
| Kats, L | 1 |
| Todorovski, I | 1 |
| Fan, Z | 1 |
| Abrehart, TC | 1 |
| Pomilio, G | 1 |
| Wei, A | 1 |
| Gregory, GP | 1 |
| Vervoort, SJ | 1 |
| Brown, KK | 1 |
| Johnstone, RW | 1 |
| Thacker, G | 1 |
| Mishra, M | 1 |
| Sharma, A | 1 |
| Singh, AK | 1 |
| Sanyal, S | 1 |
| Trivedi, AK | 1 |
| Di Marcantonio, D | 1 |
| Martinez, E | 1 |
| Kanefsky, JS | 1 |
| Huhn, JM | 1 |
| Gabbasov, R | 1 |
| Gupta, A | 1 |
| Krais, JJ | 1 |
| Peri, S | 1 |
| Tan, Y | 1 |
| Skorski, T | 1 |
| Dorrance, A | 1 |
| Garzon, R | 1 |
| Goldman, AR | 1 |
| Tang, HY | 1 |
| Johnson, N | 1 |
| Sykes, SM | 1 |
| Takami, M | 1 |
| Katayama, K | 1 |
| Noguchi, K | 1 |
| Sugimoto, Y | 1 |
| Yuan, LL | 1 |
| Green, AS | 2 |
| Bertoli, S | 1 |
| Grimal, F | 1 |
| Mansat-De Mas, V | 1 |
| Dozier, C | 1 |
| Tamburini, J | 2 |
| Récher, C | 2 |
| Didier, C | 1 |
| Manenti, S | 1 |
| Brault, L | 1 |
| Rovó, A | 1 |
| Decker, S | 1 |
| Dierks, C | 1 |
| Tzankov, A | 1 |
| Schwaller, J | 1 |
| Natarajan, K | 1 |
| Xie, Y | 1 |
| Burcu, M | 1 |
| Linn, DE | 1 |
| Qiu, Y | 1 |
| Baer, MR | 1 |
| Huang, Y | 1 |
| Thoms, JA | 1 |
| Tursky, ML | 1 |
| Knezevic, K | 1 |
| Beck, D | 1 |
| Chandrakanthan, V | 1 |
| Suryani, S | 1 |
| Olivier, J | 1 |
| Boulton, A | 1 |
| Glaros, EN | 1 |
| Thomas, SR | 1 |
| Lock, RB | 1 |
| MacKenzie, KL | 1 |
| Bushweller, JH | 1 |
| Wong, JW | 1 |
| Pimanda, JE | 1 |
| Gallay, N | 1 |
| Dos Santos, C | 1 |
| Cuzin, L | 1 |
| Bousquet, M | 1 |
| Simmonet Gouy, V | 1 |
| Chaussade, C | 1 |
| Attal, M | 1 |
| Payrastre, B | 1 |
| Demur, C | 1 |
| Chapuis, N | 1 |
| Park, S | 1 |
| Leotoing, L | 1 |
| Verdier, F | 1 |
| Bardet, V | 1 |
| Willems, L | 1 |
| Agou, F | 1 |
| Ifrah, N | 1 |
| Dreyfus, F | 1 |
| Bismuth, G | 1 |
| Baud, V | 1 |
| Lacombe, C | 1 |
| Mayeux, P | 1 |
| Bouscary, D | 1 |
| Fragliasso, V | 1 |
| Chiodo, Y | 1 |
| Ferrari-Amorotti, G | 1 |
| Soliera, AR | 1 |
| Manzotti, G | 1 |
| Cattelani, S | 1 |
| Candini, O | 1 |
| Grisendi, G | 1 |
| Vergalli, J | 1 |
| Mariani, SA | 1 |
| Guerzoni, C | 1 |
| Calabretta, B | 1 |
| Radomska, HS | 2 |
| Alberich-Jordà, M | 1 |
| Will, B | 1 |
| Gonzalez, D | 1 |
| Delwel, R | 1 |
| Tenen, DG | 2 |
| Simone, F | 1 |
| Luo, RT | 1 |
| Polak, PE | 1 |
| Kaberlein, JJ | 1 |
| Thirman, MJ | 1 |
| Bassères, DS | 1 |
| Zheng, R | 1 |
| Zhang, P | 1 |
| Dayaram, T | 1 |
| Yamamoto, Y | 1 |
| Sternberg, DW | 1 |
| Lokker, N | 1 |
| Giese, NA | 1 |
| Bohlander, SK | 1 |
| Schnittger, S | 1 |
| Delmotte, MH | 1 |
| Davis, RJ | 1 |
| Small, D | 1 |
| Hiddemann, W | 1 |
| Gilliland, DG | 1 |
| Odgerel, T | 1 |
| Kikuchi, J | 1 |
| Wada, T | 1 |
| Shimizu, R | 1 |
| Futaki, K | 1 |
| Kano, Y | 1 |
| Furukawa, Y | 1 |
| Dimitrov, NV | 1 |
| Hansz, J | 1 |
| Toth, MA | 1 |
| Bartolotta, B | 1 |
20 other studies available for serine and Leukemia, Myeloid, Acute
| Article | Year |
|---|---|
Proteomic and phosphoproteomic landscapes of acute myeloid leukemia.
Topics: fms-Like Tyrosine Kinase 3; Histone Demethylases; Humans; Jumonji Domain-Containing Histone Demethyl | 2022 |
Synergistic Targeting of DNA-PK and KIT Signaling Pathways in KIT Mutant Acute Myeloid Leukemia.
Topics: Animals; Apoptosis; Cell Line, Tumor; Dasatinib; DNA; DNA-Activated Protein Kinase; Leukemia, Myeloi | 2023 |
EVI1 phosphorylation at S436 regulates interactions with CtBP1 and DNMT3A and promotes self-renewal.
Topics: Alcohol Oxidoreductases; Cell Self Renewal; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; D | 2020 |
High Fructose Drives the Serine Synthesis Pathway in Acute Myeloid Leukemic Cells.
Topics: Animals; Fructose; Humans; Leukemia, Myeloid, Acute; Mice; Mice, Congenic; Mice, Inbred NOD; Serine; | 2021 |
Serine Biosynthesis Is a Metabolic Vulnerability in FLT3-ITD-Driven Acute Myeloid Leukemia.
Topics: Animals; Cell Line, Tumor; Disease Models, Animal; fms-Like Tyrosine Kinase 3; Humans; Leukemia, Mye | 2021 |
CDK2-instigates C/EBPα degradation through SKP2 in Acute myeloid leukemia.
Topics: CCAAT-Enhancer-Binding Proteins; Cell Differentiation; Cell Line, Tumor; Cyclin-Dependent Kinase 2; | 2021 |
ATF3 coordinates serine and nucleotide metabolism to drive cell cycle progression in acute myeloid leukemia.
Topics: Activating Transcription Factor 3; Cell Cycle; Cell Line, Tumor; Humans; Leukemia, Myeloid, Acute; N | 2021 |
Protein kinase C alpha-mediated phosphorylation of PIM-1L promotes the survival and proliferation of acute myeloid leukemia cells.
Topics: Apoptosis; Cell Line, Tumor; Cell Proliferation; Humans; Leukemia, Myeloid, Acute; Phosphorylation; | 2018 |
Pim kinases phosphorylate Chk1 and regulate its functions in acute myeloid leukemia.
Topics: Cell Line, Tumor; Checkpoint Kinase 1; fms-Like Tyrosine Kinase 3; Gene Duplication; Humans; Intrace | 2014 |
CXCR4-SERINE339 regulates cellular adhesion, retention and mobilization, and is a marker for poor prognosis in acute myeloid leukemia.
Topics: Adult; Aged; Aged, 80 and over; Biomarkers; Cell Adhesion; Female; Humans; Leukemia, Myeloid, Acute; | 2014 |
Pim-1 kinase phosphorylates and stabilizes 130 kDa FLT3 and promotes aberrant STAT5 signaling in acute myeloid leukemia with FLT3 internal tandem duplication.
Topics: Animals; Apoptosis; Calnexin; Cell Line; Cell Proliferation; Endoplasmic Reticulum; fms-Like Tyrosin | 2013 |
MAPK/ERK2 phosphorylates ERG at serine 283 in leukemic cells and promotes stem cell signatures and cell proliferation.
Topics: Binding Sites; Cell Line, Tumor; Cell Proliferation; Hematopoietic Stem Cells; Humans; Leukemia; Leu | 2016 |
The level of AKT phosphorylation on threonine 308 but not on serine 473 is associated with high-risk cytogenetics and predicts poor overall survival in acute myeloid leukaemia.
Topics: Adolescent; Adult; Apoptosis; Cell Proliferation; Cytogenetic Analysis; Female; Humans; Leukemia, My | 2009 |
IκB kinase overcomes PI3K/Akt and ERK/MAPK to control FOXO3a activity in acute myeloid leukemia.
Topics: Apoptosis; Cell Nucleus; Cell Proliferation; Extracellular Signal-Regulated MAP Kinases; Forkhead Bo | 2010 |
Phosphorylation of serine 21 modulates the proliferation inhibitory more than the differentiation inducing effects of C/EBPα in K562 cells.
Topics: Amino Acid Substitution; Base Sequence; Benzamides; CCAAT-Enhancer-Binding Protein-alpha; Cell Diffe | 2012 |
Targeting CDK1 promotes FLT3-activated acute myeloid leukemia differentiation through C/EBPα.
Topics: Animals; Base Sequence; CCAAT-Enhancer-Binding Protein-alpha; CDC2 Protein Kinase; Cell Differentiat | 2012 |
ELL-associated factor 2 (EAF2), a functional homolog of EAF1 with alternative ELL binding properties.
Topics: Amino Acid Sequence; Animals; Aspartic Acid; Binding Sites; Blotting, Northern; Bone Marrow; Cell Nu | 2003 |
Block of C/EBP alpha function by phosphorylation in acute myeloid leukemia with FLT3 activating mutations.
Topics: Aged; CCAAT-Enhancer-Binding Protein-alpha; Cell Differentiation; Cell Line; Enzyme Activation; Fema | 2006 |
The FLT3 inhibitor PKC412 exerts differential cell cycle effects on leukemic cells depending on the presence of FLT3 mutations.
Topics: Apoptosis; bcl-Associated Death Protein; CDC2 Protein Kinase; Cell Cycle; Cell Line, Tumor; Cell Pro | 2008 |
Serine and aspartic acid metabolism in leukemic leukocytes: correlation to effectiveness of therapy.
Topics: Adult; Aged; Aspartic Acid; Blood Proteins; Carbon Dioxide; Carbon Isotopes; Female; Glycine; Humans | 1971 |