serine has been researched along with Leukemia, Myelogenous, Chronic, BCR-ABL Positive in 7 studies
Serine: A non-essential amino acid occurring in natural form as the L-isomer. It is synthesized from GLYCINE or THREONINE. It is involved in the biosynthesis of PURINES; PYRIMIDINES; and other amino acids.
serine : An alpha-amino acid that is alanine substituted at position 3 by a hydroxy group.
Leukemia, Myelogenous, Chronic, BCR-ABL Positive: Clonal hematopoetic disorder caused by an acquired genetic defect in PLURIPOTENT STEM CELLS. It starts in MYELOID CELLS of the bone marrow, invades the blood and then other organs. The condition progresses from a stable, more indolent, chronic phase (LEUKEMIA, MYELOID, CHRONIC PHASE) lasting up to 7 years, to an advanced phase composed of an accelerated phase (LEUKEMIA, MYELOID, ACCELERATED PHASE) and BLAST CRISIS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Despite the use of targeted therapy, chronic myelogenous leukemia (CML) currently remains incurable with drug therapy, with patients requiring life-long treatment." | 1.40 | Serine and proline-rich ligands enriched via phage-display technology show preferential binding to BCR/ABL expressing cells. ( Jaymacker, J; Mowla, S; Njikan, S; Novitzky, N; Shankland, I; Shires, K, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (71.43) | 29.6817 |
| 2010's | 1 (14.29) | 24.3611 |
| 2020's | 1 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Yang, J | 1 |
| Cao, D | 1 |
| Zhang, Y | 1 |
| Ou, R | 1 |
| Yin, Z | 1 |
| Liu, Y | 1 |
| Huang, G | 1 |
| Gu, C | 1 |
| Chen, S | 1 |
| Fei, J | 1 |
| Shires, K | 1 |
| Shankland, I | 1 |
| Mowla, S | 1 |
| Njikan, S | 1 |
| Jaymacker, J | 1 |
| Novitzky, N | 1 |
| Müller-Tidow, C | 1 |
| Kiehl, M | 1 |
| Sindermann, JR | 1 |
| Probst, M | 1 |
| Banger, N | 1 |
| Zühlsdorf, M | 1 |
| Chou, TC | 1 |
| Berdel, WE | 1 |
| Serve, H | 1 |
| Koch, OM | 1 |
| Sawafuji, K | 1 |
| Miyakawa, Y | 1 |
| Weisberg, E | 1 |
| Griffin, JD | 1 |
| Ikeda, Y | 1 |
| Kizaki, M | 1 |
| Goldberg, Z | 1 |
| Levav, Y | 1 |
| Krichevsky, S | 1 |
| Fibach, E | 1 |
| Haupt, Y | 1 |
| Kaur, S | 1 |
| Parmar, S | 1 |
| Smith, J | 1 |
| Katsoulidis, E | 1 |
| Li, Y | 1 |
| Sassano, A | 1 |
| Majchrzak, B | 1 |
| Uddin, S | 1 |
| Tallman, MS | 1 |
| Fish, EN | 1 |
| Platanias, LC | 1 |
| Lin, F | 1 |
| Monaco, G | 1 |
| Sun, T | 1 |
| Liu, J | 1 |
| Lin, H | 1 |
| Stephens, C | 1 |
| Belmont, J | 1 |
| Arlinghaus, RB | 1 |
7 other studies available for serine and Leukemia, Myelogenous, Chronic, BCR-ABL Positive
| Article | Year |
|---|---|
The role of phosphorylation of MLF2 at serine 24 in BCR-ABL leukemogenesis.
Topics: Animals; Apoptosis; Carcinogenesis; Cell Proliferation; Colony-Forming Units Assay; Drug Resistance, | 2020 |
Serine and proline-rich ligands enriched via phage-display technology show preferential binding to BCR/ABL expressing cells.
Topics: Amino Acid Sequence; Animals; Cell Surface Display Techniques; Clone Cells; Fibroblasts; Fusion Prot | 2014 |
Synergistic growth inhibitory effects of interferon-alpha and lovastatin on bcr-abl positive leukemic cells.
Topics: Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Division; Cell Line, Tumor; DNA Fragmentation; Do | 2003 |
Aminopeptidase inhibitors inhibit proliferation and induce apoptosis of K562 and STI571-resistant K562 cell lines through the MAPK and GSK-3beta pathways.
Topics: Aminopeptidases; Anti-Bacterial Agents; Antineoplastic Agents; Apoptosis; Benzamides; Caspase 3; Cas | 2003 |
Treatment of chronic myeloid leukemia cells with imatinib (STI571) impairs p53 accumulation in response to DNA damage.
Topics: Antineoplastic Agents; Benzamides; Cell Line; Cell Line, Tumor; Checkpoint Kinase 1; Checkpoint Kina | 2004 |
Role of protein kinase C-delta (PKC-delta) in the generation of the effects of IFN-alpha in chronic myelogenous leukemia cells.
Topics: Cell Line, Tumor; DNA-Binding Proteins; Enzyme Activation; Humans; Immunoprecipitation; Interferon-a | 2005 |
BCR gene expression blocks Bcr-Abl induced pathogenicity in a mouse model.
Topics: Animals; Fusion Proteins, bcr-abl; Gene Expression Regulation; Humans; K562 Cells; Leukemia, Myeloge | 2001 |