serine has been researched along with Leucocythaemia in 27 studies
Serine: A non-essential amino acid occurring in natural form as the L-isomer. It is synthesized from GLYCINE or THREONINE. It is involved in the biosynthesis of PURINES; PYRIMIDINES; and other amino acids.
serine : An alpha-amino acid that is alanine substituted at position 3 by a hydroxy group.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (33.33) | 18.7374 |
| 1990's | 2 (7.41) | 18.2507 |
| 2000's | 8 (29.63) | 29.6817 |
| 2010's | 8 (29.63) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Berger, A | 1 |
| Hoelbl-Kovacic, A | 1 |
| Bourgeais, J | 1 |
| Hoefling, L | 1 |
| Warsch, W | 1 |
| Grundschober, E | 1 |
| Uras, IZ | 1 |
| Menzl, I | 1 |
| Putz, EM | 1 |
| Hoermann, G | 1 |
| Schuster, C | 1 |
| Fajmann, S | 2 |
| Leitner, E | 1 |
| Kubicek, S | 1 |
| Moriggl, R | 2 |
| Gouilleux, F | 2 |
| Sexl, V | 2 |
| Kuželová, K | 1 |
| Grebeňová, D | 1 |
| Holoubek, A | 1 |
| Röselová, P | 1 |
| Obr, A | 1 |
| Yin, T | 1 |
| Lallena, MJ | 1 |
| Kreklau, EL | 1 |
| Fales, KR | 1 |
| Carballares, S | 1 |
| Torrres, R | 1 |
| Wishart, GN | 1 |
| Ajamie, RT | 1 |
| Cronier, DM | 1 |
| Iversen, PW | 1 |
| Meier, TI | 1 |
| Foreman, RT | 1 |
| Zeckner, D | 1 |
| Sissons, SE | 1 |
| Halstead, BW | 1 |
| Lin, AB | 1 |
| Donoho, GP | 1 |
| Qian, Y | 1 |
| Li, S | 1 |
| Wu, S | 1 |
| Aggarwal, A | 1 |
| Ye, XS | 1 |
| Starling, JJ | 1 |
| Gaynor, RB | 1 |
| de Dios, A | 1 |
| Du, J | 1 |
| Yamagishi, N | 1 |
| Nakao, R | 1 |
| Kondo, R | 1 |
| Nishitsuji, M | 1 |
| Saito, Y | 1 |
| Kuga, T | 1 |
| Hatayama, T | 1 |
| Nakayama, Y | 1 |
| Polet, F | 1 |
| Corbet, C | 1 |
| Pinto, A | 1 |
| Rubio, LI | 1 |
| Martherus, R | 1 |
| Bol, V | 1 |
| Drozak, X | 1 |
| Grégoire, V | 1 |
| Riant, O | 1 |
| Feron, O | 1 |
| Huang, Y | 1 |
| Thoms, JA | 1 |
| Tursky, ML | 1 |
| Knezevic, K | 1 |
| Beck, D | 1 |
| Chandrakanthan, V | 1 |
| Suryani, S | 1 |
| Olivier, J | 1 |
| Boulton, A | 1 |
| Glaros, EN | 1 |
| Thomas, SR | 1 |
| Lock, RB | 1 |
| MacKenzie, KL | 1 |
| Bushweller, JH | 1 |
| Wong, JW | 1 |
| Pimanda, JE | 1 |
| Jang, SW | 1 |
| Yang, SJ | 1 |
| Ehlén, A | 1 |
| Dong, S | 1 |
| Khoury, H | 1 |
| Chen, J | 1 |
| Persson, JL | 1 |
| Ye, K | 1 |
| Tichý, A | 1 |
| Záskodová, D | 1 |
| Zoelzer, F | 1 |
| Vávrová, J | 1 |
| Sinkorová, Z | 1 |
| Pejchal, J | 1 |
| Osterreicher, J | 1 |
| Rezácová, M | 1 |
| Cao, J | 1 |
| Xu, D | 1 |
| Wang, D | 1 |
| Wu, R | 1 |
| Zhang, L | 1 |
| Zhu, H | 1 |
| He, Q | 1 |
| Yang, B | 1 |
| Friedbichler, K | 1 |
| Kerenyi, MA | 1 |
| Kovacic, B | 1 |
| Li, G | 1 |
| Hoelbl, A | 1 |
| Yahiaoui, S | 1 |
| Müllner, EW | 1 |
| Cerny-Reiterer, S | 1 |
| Valent, P | 1 |
| Beug, H | 1 |
| Bunting, KD | 1 |
| Tamaichi, H | 1 |
| Sato, M | 1 |
| Porter, AC | 1 |
| Shimizu, T | 1 |
| Mizutani, S | 1 |
| Takagi, M | 1 |
| Azuma, H | 1 |
| Takao, R | 1 |
| Niiro, H | 1 |
| Shikata, K | 1 |
| Tamagaki, S | 1 |
| Tachibana, T | 1 |
| Ogino, K | 1 |
| Sgarra, R | 1 |
| Diana, F | 1 |
| Rustighi, A | 1 |
| Manfioletti, G | 1 |
| Giancotti, V | 1 |
| Wilson, GM | 1 |
| Lu, J | 1 |
| Sutphen, K | 1 |
| Sun, Y | 1 |
| Huynh, Y | 1 |
| Brewer, G | 1 |
| Ito, K | 1 |
| Nakazato, T | 1 |
| Yamato, K | 1 |
| Miyakawa, Y | 1 |
| Yamada, T | 1 |
| Hozumi, N | 1 |
| Segawa, K | 1 |
| Ikeda, Y | 1 |
| Kizaki, M | 1 |
| Hara, T | 1 |
| Suzuki, Y | 1 |
| Semba, T | 1 |
| Hatanaka, M | 1 |
| Matsumoto, M | 1 |
| Seya, T | 1 |
| Ruvolo, PP | 1 |
| Deng, X | 1 |
| May, WS | 1 |
| Thorndike, J | 1 |
| Pelliniemi, TT | 1 |
| Beck, WS | 1 |
| Wiseman, C | 1 |
| McGregor, RF | 1 |
| McCredie, KB | 1 |
| Adler, V | 1 |
| Polotskaya, A | 1 |
| Wagner, F | 1 |
| Kraft, AS | 1 |
| Amson, RB | 1 |
| Marcelle, C | 1 |
| Telerman, A | 1 |
| Pizer, LI | 1 |
| Regan, JD | 1 |
| Jones, C | 1 |
| Wuthier, P | 1 |
| Kao, FT | 1 |
| Puck, TT | 1 |
| Bertino, JR | 1 |
| Hillcoat, BL | 1 |
| Groth, DP | 1 |
| D'Angelo, JM | 1 |
| Vogler, WR | 1 |
| Mingioli, ES | 1 |
| Betz, B | 1 |
| Zozuliakova, SV | 1 |
| Kolosova, NN | 1 |
| Grignani, F | 1 |
| Martelli, M | 1 |
| Tonato, M | 1 |
| Colonna, A | 1 |
2 reviews available for serine and Leucocythaemia
| Article | Year |
|---|---|
Phosphorylation of Bcl2 and regulation of apoptosis.
Topics: Animals; Apoptosis; Humans; Leukemia; Lymphoma; Phosphorylation; Protein Processing, Post-Translatio | 2001 |
Regulation of dihydrofolate reductase and other folate-requiring enzymes.
Topics: Alcohol Oxidoreductases; Animals; Enzyme Induction; Erythrocytes; Escherichia coli; Folic Acid; Foli | 1968 |
25 other studies available for serine and Leucocythaemia
| Article | Year |
|---|---|
PAK-dependent STAT5 serine phosphorylation is required for BCR-ABL-induced leukemogenesis.
Topics: Animals; Base Sequence; Cell Line, Tumor; Cell Nucleus; Cells, Cultured; DNA Primers; Fusion Protein | 2014 |
Group I PAK inhibitor IPA-3 induces cell death and affects cell adhesivity to fibronectin in human hematopoietic cells.
Topics: Actin Depolymerizing Factors; Apoptosis; Blood Cells; Cell Adhesion; Cell Proliferation; Disulfides; | 2014 |
A novel CDK9 inhibitor shows potent antitumor efficacy in preclinical hematologic tumor models.
Topics: Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cyclin-Dependent Kinase 9; Cyclohexylamines; Hum | 2014 |
Increased expression of sorcin is associated with multidrug resistance in leukemia cells via up-regulation of MDR1 expression through cAMP response element-binding protein.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily | 2014 |
Reducing the serine availability complements the inhibition of the glutamine metabolism to block leukemia cell growth.
Topics: Animals; Cell Line, Tumor; Cell Proliferation; Cell Survival; Electrophoresis, Gel, Two-Dimensional; | 2016 |
MAPK/ERK2 phosphorylates ERG at serine 283 in leukemic cells and promotes stem cell signatures and cell proliferation.
Topics: Binding Sites; Cell Line, Tumor; Cell Proliferation; Hematopoietic Stem Cells; Humans; Leukemia; Leu | 2016 |
Serine/arginine protein-specific kinase 2 promotes leukemia cell proliferation by phosphorylating acinus and regulating cyclin A1.
Topics: Bone Marrow; Cell Cycle; Cell Nucleus; Cell Proliferation; Cyclin A; Cyclin A1; Flow Cytometry; Fluo | 2008 |
Gamma-radiation-induced phosphorylation of p53 on serine 15 is dose-dependent in MOLT-4 leukaemia cells.
Topics: Cell Line, Tumor; Cell Proliferation; Gamma Rays; Humans; Leukemia; Phosphorylation; Serine; Tumor S | 2009 |
ROS-driven Akt dephosphorylation at Ser-473 is involved in 4-HPR-mediated apoptosis in NB4 cells.
Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Chromones; Dose-Response Relationship, | 2009 |
Stat5a serine 725 and 779 phosphorylation is a prerequisite for hematopoietic transformation.
Topics: Adult; Aged; Animals; Blotting, Western; Bone Marrow Transplantation; Cell Lineage; Cell Proliferati | 2010 |
Ataxia telangiectasia mutated-dependent regulation of topoisomerase II alpha expression and sensitivity to topoisomerase II inhibitor.
Topics: Alanine; Antigens, Neoplasm; Ataxia Telangiectasia Mutated Proteins; Cell Cycle Proteins; Cell Line, | 2013 |
Total syntheses of symbioramide derivatives from l-serine and their antileukemic activities.
Topics: Animals; Antineoplastic Agents; Catalysis; Combinatorial Chemistry Techniques; HL-60 Cells; Humans; | 2003 |
Increase of HMGA1a protein methylation is a distinctive characteristic of leukaemic cells induced to undergo apoptosis.
Topics: Apoptosis; Chromatin; Chromatography, High Pressure Liquid; HMGA1a Protein; Humans; Leukemia; Methyl | 2003 |
Regulation of A + U-rich element-directed mRNA turnover involving reversible phosphorylation of AUF1.
Topics: Amino Acid Sequence; Base Sequence; Blotting, Western; Cell Adhesion; Cell Line; Cytoplasm; Dactinom | 2003 |
Induction of apoptosis in leukemic cells by homovanillic acid derivative, capsaicin, through oxidative stress: implication of phosphorylation of p53 at Ser-15 residue by reactive oxygen species.
Topics: Apoptosis; Capsaicin; Cell Division; Cell Line, Tumor; G1 Phase; Humans; Leukemia; Mitochondria; Oxi | 2004 |
High expression of membrane cofactor protein of complement (CD46) in human leukaemia cell lines: implication of an alternatively spliced form containing the STA domain in CD46 up-regulation.
Topics: Alternative Splicing; Amino Acid Sequence; Antibodies; Antibody Specificity; Antigens, CD; B-Lymphoc | 1995 |
Serine hydroxymethyltransferase activity and serine incorporation in leukocytes.
Topics: DNA; DNA, Neoplasm; Glycine Hydroxymethyltransferase; Granulocytes; Humans; Leukemia; Leukocytes; Ly | 1979 |
Urinary amino acid excretion in acute leukemia.
Topics: Amino Acids; Antineoplastic Agents; Aspartic Acid; Female; Humans; Leukemia; Male; Remission, Sponta | 1976 |
Affinity-purified c-Jun amino-terminal protein kinase requires serine/threonine phosphorylation for activity.
Topics: Cell Line; Chromatography, Affinity; Glutathione Transferase; Humans; Kinetics; Leukemia; Phosphopro | 1992 |
Identification of a 130 Kda bcr related gene product.
Topics: Amino Acids; Leukemia; Phosphorylation; Protein Kinases; Protein-Tyrosine Kinases; Proto-Oncogene Pr | 1989 |
Basis for the serine requirement in leukemic and normal human leukocytes. Reduced levels of the enzymes in the phosphorylated pathway.
Topics: Carbon Isotopes; Carcinoma; Cell Line; Fibroblasts; Glycerolphosphate Dehydrogenase; HeLa Cells; Hum | 1972 |
Genetics of somatic mammalian cells. XV. Evidence for linkage between human genes for lactic dehydrogenase B and serine hydroxymethylase.
Topics: Amniotic Fluid; Animals; Bone Marrow; Bone Marrow Cells; Cell Line; Clone Cells; Cricetinae; Electro | 1972 |
Selective metabolic effects of 1,3-bis(2-chloroethyl)-1-nitrosourea upon de novo purine biosynthesis.
Topics: Acute Disease; Amino Acids; Animals; Antineoplastic Agents; Ascitic Fluid; Carbon Isotopes; Carcinom | 1971 |
[Free serum amino acids in leukosis].
Topics: Adult; Amino Acids; Central Nervous System Diseases; Histidine; Humans; Leukemia; Leukemia, Lymphoid | 1969 |
Purification and properties of serine hydroxymethylase from human leukaemic leukocytes.
Topics: Humans; Leukemia; Leukocytes; Mixed Function Oxygenases; Pyridoxal Phosphate; Serine | 1965 |